6BYJ
 
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1UPF
 | | STRUCTURE OF THE URACIL PHOSPHORIBOSYLTRANSFERASE, MUTANT C128V BOUND TO THE DRUG 5-FLUOROURACIL | | 分子名称: | 5-FLUOROURACIL, SULFATE ION, URACIL PHOSPHORIBOSYLTRANSFERASE | | 著者 | Schumacher, M.A, Carter, D, Scott, D, Roos, D, Ullman, B, Brennan, R.G. | | 登録日 | 1998-06-17 | | 公開日 | 1999-06-22 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structures of Toxoplasma gondii uracil phosphoribosyltransferase reveal the atomic basis of pyrimidine discrimination and prodrug binding.
EMBO J., 17, 1998
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5TZF
 | | Structure of the BldD CTD(D116A)-(c-di-GMP)2 intermediate, form 1 | | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), DNA-binding protein | | 著者 | Schumacher, M.A. | | 登録日 | 2016-11-21 | | 公開日 | 2017-04-19 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | The Streptomyces master regulator BldD binds c-di-GMP sequentially to create a functional BldD2-(c-di-GMP)4 complex.
Nucleic Acids Res., 45, 2017
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6BYK
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6BZD
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4YJ1
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8SVA
 | | Structure of the Rhodococcus sp. USK13 DarR-20 bp DNA complex | | 分子名称: | DNA (5'-D(*TP*AP*GP*AP*TP*AP*CP*TP*CP*CP*GP*GP*AP*GP*TP*AP*TP*CP*TP*A)-3'), PHOSPHATE ION, TetR/AcrR family transcriptional regulator | | 著者 | Schumacher, M.A. | | 登録日 | 2023-05-15 | | 公開日 | 2023-11-01 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.96 Å) | | 主引用文献 | Structures of the DarR transcription regulator reveal unique modes of second messenger and DNA binding.
Nat Commun, 14, 2023
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8SUA
 | | Structure of M. baixiangningiae DarR-ligand complex | | 分子名称: | 3-azanyl-3-(hydroxymethyl)-1,5,7,11-tetraoxa-6$l^{4}-boraspiro[5.5]undecan-9-ol, DarR | | 著者 | Schumacher, M.A. | | 登録日 | 2023-05-11 | | 公開日 | 2023-11-01 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structures of the DarR transcription regulator reveal unique modes of second messenger and DNA binding.
Nat Commun, 14, 2023
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7U02
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8TFK
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8TFB
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8UFJ
 | | Structure of M. mazei GS(R167L-A168G) apo form | | 分子名称: | Glutamine synthetase, MAGNESIUM ION | | 著者 | Schumacher, M.A. | | 登録日 | 2023-10-04 | | 公開日 | 2023-11-15 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | M. mazei glutamine synthetase and glutamine synthetase-GlnK1 structures reveal enzyme regulation by oligomer modulation.
Nat Commun, 14, 2023
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5HBU
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3MKY
 | | Structure of SopB(155-323)-18mer DNA complex, I23 form | | 分子名称: | DNA (5'-D(*CP*TP*GP*GP*GP*AP*CP*CP*AP*TP*GP*GP*TP*CP*CP*CP*AP*G)-3'), Protein sopB, SULFATE ION | | 著者 | Schumacher, M.A, Piro, K, Xu, W. | | 登録日 | 2010-04-15 | | 公開日 | 2010-05-05 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.86 Å) | | 主引用文献 | Insight into F plasmid DNA segregation revealed by structures of SopB and SopB-DNA complexes.
Nucleic Acids Res., 38, 2010
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3MKW
 | | Structure of sopB(155-272)-18mer complex, I23 form | | 分子名称: | DNA (5'-D(*CP*TP*GP*GP*GP*AP*CP*CP*AP*TP*GP*GP*TP*CP*CP*CP*AP*G)-3'), Protein sopB, SULFATE ION | | 著者 | Schumacher, M.A, Piro, K, Xu, W. | | 登録日 | 2010-04-15 | | 公開日 | 2010-05-05 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | | 主引用文献 | Insight into F plasmid DNA segregation revealed by structures of SopB and SopB-DNA complexes.
Nucleic Acids Res., 38, 2010
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8SUK
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8SV6
 | | Structure of the M. smegmatis DarR protein | | 分子名称: | Fatty acid metabolism regulator protein | | 著者 | Schumacher, M.A. | | 登録日 | 2023-05-15 | | 公開日 | 2023-11-01 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.56 Å) | | 主引用文献 | Structures of the DarR transcription regulator reveal unique modes of second messenger and DNA binding.
Nat Commun, 14, 2023
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1LII
 | | STRUCTURE OF T. GONDII ADENOSINE KINASE BOUND TO ADENOSINE 2 AND AMP-PCP | | 分子名称: | ADENOSINE, CHLORIDE ION, MAGNESIUM ION, ... | | 著者 | Schumacher, M.A, Scott, D.M, Mathews, I.I, Ealick, S.E, Roos, D.S, Ullman, B, Brennan, R.G. | | 登録日 | 2002-04-17 | | 公開日 | 2002-05-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Crystal structures of Toxoplasma gondii adenosine kinase reveal a novel catalytic mechanism and prodrug binding.
J.Mol.Biol., 298, 2000
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1LIJ
 | | STRUCTURE OF T. GONDII ADENOSINE KINASE BOUND TO PRODRUG 2 7-IODOTUBERCIDIN AND AMP-PCP | | 分子名称: | 2-RIBOFURANOSYL-3-IODO-2,3-DIHYDRO-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YLAMINE, CHLORIDE ION, MAGNESIUM ION, ... | | 著者 | Schumacher, M.A, Scott, D.M, Mathews, I.I, Ealick, S.E, Roos, D.S, Ullman, B, Brennan, R.G. | | 登録日 | 2002-04-17 | | 公開日 | 2002-05-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Crystal structures of Toxoplasma gondii adenosine kinase reveal a novel catalytic mechanism and prodrug binding.
J.Mol.Biol., 298, 2000
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7RMW
 | | Crystal structure of B. subtilis PurR bound to ppGpp | | 分子名称: | GUANOSINE-5',3'-TETRAPHOSPHATE, Pur operon repressor | | 著者 | Schumacher, M.A. | | 登録日 | 2021-07-28 | | 公開日 | 2021-12-22 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | The nucleotide messenger (p)ppGpp is an anti-inducer of the purine synthesis transcription regulator PurR in Bacillus.
Nucleic Acids Res., 50, 2022
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1LIK
 | | STRUCTURE OF T. GONDII ADENOSINE KINASE BOUND TO ADENOSINE | | 分子名称: | ADENOSINE, CHLORIDE ION, SULFATE ION, ... | | 著者 | Schumacher, M.A, Scott, D.M, Mathews, I.I, Ealick, S.E, Roos, D.S, Ullman, B, Brennan, R.G. | | 登録日 | 2002-04-17 | | 公開日 | 2002-05-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Crystal structures of Toxoplasma gondii adenosine kinase reveal a novel catalytic mechanism and prodrug binding.
J.Mol.Biol., 298, 2000
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1LIO
 | | STRUCTURE OF APO T. GONDII ADENOSINE KINASE | | 分子名称: | adenosine kinase | | 著者 | Schumacher, M.A, Scott, D.M, Mathews, I.I, Ealick, S.E, Brennan, R.G. | | 登録日 | 2002-04-17 | | 公開日 | 2002-06-12 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structures of Toxoplasma gondii adenosine kinase reveal a novel catalytic mechanism and prodrug binding.
J.Mol.Biol., 298, 2000
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8TP8
 | | Structure of the C. crescentus WYL-activator, DriD, bound to ssDNA and cognate DNA | | 分子名称: | DNA (5'-D(*AP*TP*AP*CP*GP*AP*CP*AP*GP*TP*AP*AP*CP*TP*GP*TP*CP*GP*TP*AP*T)-3'), DNA (5'-D(*AP*TP*AP*CP*GP*AP*CP*AP*GP*TP*TP*AP*CP*TP*GP*TP*CP*GP*TP*AP*T)-3'), DNA (5'-D(P*GP*TP*C)-3'), ... | | 著者 | Schumacher, M.A. | | 登録日 | 2023-08-04 | | 公開日 | 2023-11-29 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | | 主引用文献 | Structure of the WYL-domain containing transcription activator, DriD, in complex with ssDNA effector and DNA target site.
Nucleic Acids Res., 52, 2024
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1WET
 | | STRUCTURE OF THE PURR-GUANINE-PURF OPERATOR COMPLEX | | 分子名称: | DNA (5'-D(*AP*AP*CP*GP*AP*AP*AP*AP*CP*GP*TP*TP*TP*TP*CP*GP*T )-3'), GUANINE, PROTEIN (PURINE REPRESSOR) | | 著者 | Schumacher, M.A, Glasfeld, A, Zalkin, H, Brennan, R.G. | | 登録日 | 1997-04-27 | | 公開日 | 1997-11-21 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The X-ray structure of the PurR-guanine-purF operator complex reveals the contributions of complementary electrostatic surfaces and a water-mediated hydrogen bond to corepressor specificity and binding affinity.
J.Biol.Chem., 272, 1997
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5E1L
 | | Structural and functional analysis of the E. coli FtsZ interacting protein, ZapC, reveals insight into molecular properties of a novel Z ring stabilizing protein | | 分子名称: | Cell division protein ZapC | | 著者 | Schumacher, M.A, Huang, K.-H, Tchorzewski, L, Zeng, W, Janakiraman, A. | | 登録日 | 2015-09-29 | | 公開日 | 2015-12-23 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structural and Functional Analyses Reveal Insights into the Molecular Properties of the Escherichia coli Z Ring Stabilizing Protein, ZapC.
J.Biol.Chem., 291, 2016
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