8K74
| A novel monooxygenase | Descriptor: | Alkanal monooxygenase alpha chain | Authors: | Ma, D, Feng, R. | Deposit date: | 2023-07-26 | Release date: | 2024-07-31 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Functional and structural analysis of monooxygenase in polyacrylamide degraded by Klebsiella sp. PCX To Be Published
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8X83
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8X84
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6BUG
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6BUH
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8X43
| human KCNQ2-CaM-Ebio1-S1 complex in the presence of PIP2 | Descriptor: | Calmodulin-1, N-(4-azanyl-1,2-dihydroacenaphthylen-5-yl)-4-fluoranyl-benzamide, Potassium voltage-gated channel subfamily KQT member 2 | Authors: | Ma, D, Guo, J. | Deposit date: | 2023-11-15 | Release date: | 2024-01-17 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | A small-molecule activation mechanism that directly opens the KCNQ2 channel. Nat.Chem.Biol., 20, 2024
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8X82
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6BUI
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1VRY
| Second and Third Transmembrane Domains of the Alpha-1 Subunit of Human Glycine Receptor | Descriptor: | Glycine receptor alpha-1 chain | Authors: | Ma, D, Liu, Z, Li, L, Tang, P, Xu, Y. | Deposit date: | 2005-07-20 | Release date: | 2005-07-26 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Structure and Dynamics of the Second and Third Transmembrane Domains of Human Glycine Receptor. Biochemistry, 44, 2005
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8JMI
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8JMH
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8JE0
| A novel amidohydrolase | Descriptor: | 1,2-ETHANEDIOL, Amidase, ZINC ION | Authors: | Ma, D, Feng, R. | Deposit date: | 2023-05-15 | Release date: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | A novel amidohydrolase catalyze the degradation of PAM by Klebsiella sp. PCX To Be Published
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8W4U
| human KCNQ2-CaM in complex with PIP2 and HN37 | Descriptor: | Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 2, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate, ... | Authors: | Ma, D, Li, X, Guo, J. | Deposit date: | 2023-08-25 | Release date: | 2023-12-13 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Ligand activation mechanisms of human KCNQ2 channel. Nat Commun, 14, 2023
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4DJK
| Structure of glutamate-GABA antiporter GadC | Descriptor: | Probable glutamate/gamma-aminobutyrate antiporter | Authors: | Ma, D, Lu, P.L, Yan, C.Y, Fan, C, Yin, P, Wang, J.W, Shi, Y.G. | Deposit date: | 2012-02-02 | Release date: | 2012-03-14 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.097 Å) | Cite: | Structure and mechanism of a glutamate-GABA antiporter Nature, 483, 2012
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4DJI
| Structure of glutamate-GABA antiporter GadC | Descriptor: | Probable glutamate/gamma-aminobutyrate antiporter | Authors: | Ma, D, Lu, P.L, Yan, C.Y, Fan, C, Yin, P, Wang, J.W, Shi, Y.G. | Deposit date: | 2012-02-02 | Release date: | 2012-03-14 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.187 Å) | Cite: | Structure and mechanism of a glutamate-GABA antiporter Nature, 483, 2012
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8I6N
| Crystal structure of Co-type nitrile hydratase mutant from Pseudomonas thermophila - L6T | Descriptor: | COBALT (II) ION, Cobalt-containing nitrile hydratase subunit alpha, Cobalt-containing nitrile hydratase subunit beta | Authors: | Ma, D, Cheng, Z.Y, Lai, Q.P, Hou, X.D, Yin, D.J, Rao, Y.J, Zhou, Z.M. | Deposit date: | 2023-01-29 | Release date: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of Co-type nitrile hydratase mutant L6T from Pseudomonas thermophila at 2.2 Angstroms resolution. To Be Published
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8JMA
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8J01
| Human KCNQ2-CaM in complex with CBD and PIP2 | Descriptor: | Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 2, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate, ... | Authors: | Ma, D, Li, X, Guo, J. | Deposit date: | 2023-04-09 | Release date: | 2023-12-13 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Ligand activation mechanisms of human KCNQ2 channel. Nat Commun, 14, 2023
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8J02
| Human KCNQ2(F104A)-CaM-PIP2-CBD complex in state II | Descriptor: | Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 2, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate, ... | Authors: | Ma, D, Li, X, Guo, J. | Deposit date: | 2023-04-09 | Release date: | 2023-12-13 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Ligand activation mechanisms of human KCNQ2 channel. Nat Commun, 14, 2023
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2K1E
| NMR studies of a channel protein without membranes: structure and dynamics of water-solubilized KcsA | Descriptor: | water soluble analogue of potassium channel, KcsA | Authors: | Ma, D, Xu, Y, Tillman, T, Tang, P, Meirovitch, E, Eckenhoff, R, Carnini, A. | Deposit date: | 2008-02-29 | Release date: | 2008-11-11 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | NMR studies of a channel protein without membranes: structure and dynamics of water-solubilized KcsA. Proc.Natl.Acad.Sci.Usa, 105, 2008
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8J03
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2KB1
| NMR studies of a channel protein without membrane: structure and dynamics of water-solubilized KcsA | Descriptor: | WSK3 | Authors: | Ma, D, Xu, Y, Tillman, T, Tang, P, Meirovitch, E, Eckenhoff, R, Carnini, A. | Deposit date: | 2008-11-19 | Release date: | 2008-12-09 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | NMR studies of a channel protein without membranes: structure and dynamics of water-solubilized KcsA Proc.Natl.Acad.Sci.USA, 105, 2008
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8IJK
| human KCNQ2-CaM-Ebio1 complex in the presence of PIP2 | Descriptor: | Calmodulin-1, N-(1,2-dihydroacenaphthylen-5-yl)-4-fluoranyl-benzamide, Potassium voltage-gated channel subfamily KQT member 2 | Authors: | Ma, D, Guo, J. | Deposit date: | 2023-02-27 | Release date: | 2024-01-17 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | A small-molecule activation mechanism that directly opens the KCNQ2 channel. Nat.Chem.Biol., 20, 2024
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7W3Y
| CryoEM structure of human Kv4.3 | Descriptor: | Isoform 2 of Potassium voltage-gated channel subfamily D member 3 | Authors: | Ma, D.M, Guo, J.T. | Deposit date: | 2021-11-26 | Release date: | 2022-11-02 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis for the gating modulation of Kv4.3 by auxiliary subunits. Cell Res., 32, 2022
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7W6S
| CryoEM structure of human KChIP2-Kv4.3 complex | Descriptor: | Isoform 2 of Potassium voltage-gated channel subfamily D member 3, Kv channel-interacting protein 2 | Authors: | Ma, D.M, Guo, J.T. | Deposit date: | 2021-12-02 | Release date: | 2022-11-02 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structural basis for the gating modulation of Kv4.3 by auxiliary subunits. Cell Res., 32, 2022
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