4KJS
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![BU of 4kjs by Molmil](/molmil-images/mine/4kjs) | Structure of native YfkE | Descriptor: | cation exchanger YfkE | Authors: | Wu, M, Tong, S, Zheng, L. | Deposit date: | 2013-05-03 | Release date: | 2013-06-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Crystal structure of Ca2+/H+ antiporter protein YfkE reveals the mechanisms of Ca2+ efflux and its pH regulation. Proc.Natl.Acad.Sci.USA, 110, 2013
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8EFO
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![BU of 8efo by Molmil](/molmil-images/mine/8efo) | PZM21-bound mu-opioid receptor-Gi complex | Descriptor: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Zhuang, Y, Wang, Y, Guo, S, Zhou, X.E, Rao, Q, He, X, He, B, Liu, J, Zhou, Q, Wang, X, Liu, W, Jiang, X, Yang, D, Chen, X, Jiang, Y, Jiang, H, Shen, J, Melcher, K, Wang, M, Xie, X, Xu, H.E. | Deposit date: | 2022-09-08 | Release date: | 2022-11-09 | Last modified: | 2022-11-30 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Molecular recognition of morphine and fentanyl by the human mu-opioid receptor. Cell, 185, 2022
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5JKL
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1UWS
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![BU of 1uws by Molmil](/molmil-images/mine/1uws) | Structure of beta-glycosidase from Sulfolobus solfataricus in complex with 2-deoxy-2-fluoro-glucose | Descriptor: | 2-deoxy-2-fluoro-alpha-D-glucopyranose, ACETATE ION, BETA-GALACTOSIDASE | Authors: | Gloster, T.M, Roberts, S, Ducros, V.M.-A, Perugino, G, Rossi, M, Hoos, R, Moracci, M, Vasella, A, Davies, G.J. | Deposit date: | 2004-02-11 | Release date: | 2004-05-20 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural studies of the beta-glycosidase from Sulfolobus solfataricus in complex with covalently and noncovalently bound inhibitors. Biochemistry, 43, 2004
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8EFL
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![BU of 8efl by Molmil](/molmil-images/mine/8efl) | SR17018-bound mu-opioid receptor-Gi complex | Descriptor: | 5,6-dichloro-1-{1-[(4-chlorophenyl)methyl]piperidin-4-yl}-1,3-dihydro-2H-benzimidazol-2-one, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Zhuang, Y, Wang, Y, Guo, S, Zhou, X.E, Rao, Q, He, X, He, B, Liu, J, Zhou, Q, Wang, X, Liu, W, Jiang, X, Yang, D, Chen, X, Jiang, Y, Jiang, H, Shen, J, Melcher, K, Wang, M, Xie, X, Xu, H.E. | Deposit date: | 2022-09-08 | Release date: | 2022-11-09 | Last modified: | 2022-11-30 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Molecular recognition of morphine and fentanyl by the human mu-opioid receptor. Cell, 185, 2022
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4KM6
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![BU of 4km6 by Molmil](/molmil-images/mine/4km6) | Human folate receptor alpha (FOLR1) at acidic pH, orthorhombic form | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Folate receptor alpha | Authors: | Singh, M, Dann III, C.E. | Deposit date: | 2013-05-08 | Release date: | 2013-08-07 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structures of human folate receptors reveal biological trafficking states and diversity in folate and antifolate recognition. Proc.Natl.Acad.Sci.USA, 110, 2013
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6GXZ
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![BU of 6gxz by Molmil](/molmil-images/mine/6gxz) | Crystal structure of the human RPAP3(TPR2)-PIH1D1(CS) complex | Descriptor: | CALCIUM ION, PIH1 domain-containing protein 1, RNA polymerase II-associated protein 3 | Authors: | Henri, J, Quinternet, M, Manival, X, Chagot, M.-E, Charpentier, B, Meyer, P. | Deposit date: | 2018-06-27 | Release date: | 2018-08-08 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.965 Å) | Cite: | Deep Structural Analysis of RPAP3 and PIH1D1, Two Components of the HSP90 Co-chaperone R2TP Complex. Structure, 26, 2018
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5B3A
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![BU of 5b3a by Molmil](/molmil-images/mine/5b3a) | Crystal Structure of O-Phoshoserine Sulfhydrylase from Aeropyrum pernix in Complexed with the alpha-Aminoacrylate Intermediate | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid, Protein CysO | Authors: | Nakamura, T, Takeda, E, Kawai, Y, Kataoka, M, Ishikawa, K. | Deposit date: | 2016-02-12 | Release date: | 2016-03-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Role of F225 in O-phosphoserine sulfhydrylase from Aeropyrum pernix K1 Extremophiles, 20, 2016
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8EFB
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![BU of 8efb by Molmil](/molmil-images/mine/8efb) | Oliceridine-bound mu-opioid receptor-Gi complex | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | Zhuang, Y, Wang, Y, Guo, S, Zhou, X.E, Rao, Q, He, X, He, B, Liu, J, Zhou, Q, Wang, X, Liu, W, Jiang, X, Yang, D, Chen, X, Jiang, Y, Jiang, H, Shen, J, Melcher, K, Wang, M, Xie, X, Xu, H.E. | Deposit date: | 2022-09-08 | Release date: | 2022-11-09 | Last modified: | 2022-11-30 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Molecular recognition of morphine and fentanyl by the human mu-opioid receptor. Cell, 185, 2022
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1AVM
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8EFQ
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![BU of 8efq by Molmil](/molmil-images/mine/8efq) | DAMGO-bound mu-opioid receptor-Gi complex | Descriptor: | DAMGO, ETHANOLAMINE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Zhuang, Y, Wang, Y, Guo, S, Zhou, X.E, Rao, Q, He, X, He, B, Liu, J, Zhou, Q, Wang, X, Liu, W, Jiang, X, Yang, D, Chen, X, Jiang, Y, Jiang, H, Shen, J, Melcher, K, Wang, M, Xie, X, Xu, H.E. | Deposit date: | 2022-09-08 | Release date: | 2022-11-09 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Molecular recognition of morphine and fentanyl by the human mu-opioid receptor. Cell, 185, 2022
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3OP4
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![BU of 3op4 by Molmil](/molmil-images/mine/3op4) | Crystal structure of putative 3-ketoacyl-(acyl-carrier-protein) reductase from Vibrio cholerae O1 biovar eltor str. N16961 in complex with NADP+ | Descriptor: | 3-oxoacyl-[acyl-carrier protein] reductase, ACETATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Hou, J, Chruszcz, M, Onopriyenko, O, Grimshaw, S, Porebski, P, Zheng, H, Savchenko, A, Anderson, W, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2010-08-31 | Release date: | 2010-09-22 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Dissecting the Structural Elements for the Activation of beta-Ketoacyl-(Acyl Carrier Protein) Reductase from Vibrio cholerae. J.Bacteriol., 198, 2015
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8B6Z
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1JE1
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![BU of 1je1 by Molmil](/molmil-images/mine/1je1) | 5'-DEOXY-5'-METHYLTHIOADENOSINE PHOSPHORYLASE COMPLEX WITH GUANOSINE AND SULFATE | Descriptor: | 5'-METHYLTHIOADENOSINE PHOSPHORYLASE, GUANOSINE, SULFATE ION | Authors: | Appleby, T.C, Mathews, I.I, Porcelli, M, Cacciapuoti, G, Ealick, S.E. | Deposit date: | 2001-06-15 | Release date: | 2001-10-26 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Three-dimensional structure of a hyperthermophilic 5'-deoxy-5'-methylthioadenosine phosphorylase from Sulfolobus solfataricus. J.Biol.Chem., 276, 2001
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4NBQ
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![BU of 4nbq by Molmil](/molmil-images/mine/4nbq) | Structure of the polynucleotide phosphorylase (CBU_0852) from Coxiella burnetii | Descriptor: | Polyribonucleotide nucleotidyltransferase, SULFATE ION | Authors: | Rudolph, M.J, Cheung, J, Franklin, M.C, Cassidy, M, Gary, E, Burshteyn, F, Love, J. | Deposit date: | 2013-10-23 | Release date: | 2015-06-17 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.9138 Å) | Cite: | Structural genomics for drug design against the pathogen Coxiella burnetii. Proteins, 83, 2015
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1B1C
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![BU of 1b1c by Molmil](/molmil-images/mine/1b1c) | CRYSTAL STRUCTURE OF THE FMN-BINDING DOMAIN OF HUMAN CYTOCHROME P450 REDUCTASE AT 1.93A RESOLUTION | Descriptor: | CALCIUM ION, FLAVIN MONONUCLEOTIDE, PROTEIN (NADPH-CYTOCHROME P450 REDUCTASE) | Authors: | Zhao, Q, Modi, S, Smith, G, Paine, M, Mcdonagh, P.D, Wolf, C.R, Tew, D, Lian, L.-Y, Roberts, G.C.K, Driessen, H.P.C. | Deposit date: | 1998-11-19 | Release date: | 1999-11-24 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Crystal structure of the FMN-binding domain of human cytochrome P450 reductase at 1.93 A resolution. Protein Sci., 8, 1999
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4TKW
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4TL4
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1T3M
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![BU of 1t3m by Molmil](/molmil-images/mine/1t3m) | Structure of the isoaspartyl peptidase with L-asparaginase activity from E. coli | Descriptor: | NITRATE ION, Putative L-asparaginase, SODIUM ION | Authors: | Prahl, A, Pazgier, M, Hejazi, M, Lockau, W, Lubkowski, J. | Deposit date: | 2004-04-27 | Release date: | 2004-07-13 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structure of the isoaspartyl peptidase with L-asparaginase activity from Escherichia coli. Acta Crystallogr.,Sect.D, 60, 2004
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5BOU
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2P39
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![BU of 2p39 by Molmil](/molmil-images/mine/2p39) | Crystal structure of human FGF23 | Descriptor: | 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, Fibroblast growth factor 23 | Authors: | Mohammadi, M. | Deposit date: | 2007-03-08 | Release date: | 2007-04-10 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members. Mol.Cell.Biol., 27, 2007
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3P8Y
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8B6L
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![BU of 8b6l by Molmil](/molmil-images/mine/8b6l) | Subtomogram average of the human Sec61-TRAP-OSTA-translocon | Descriptor: | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2, ... | Authors: | Gemmer, M, Fedry, J.M.M, Forster, F.G. | Deposit date: | 2022-09-27 | Release date: | 2022-12-07 | Last modified: | 2023-02-08 | Method: | ELECTRON MICROSCOPY (7.6 Å) | Cite: | Visualization of translation and protein biogenesis at the ER membrane. Nature, 614, 2023
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6H67
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![BU of 6h67 by Molmil](/molmil-images/mine/6h67) | Yeast RNA polymerase I elongation complex stalled by cyclobutane pyrimidine dimer (CPD) | Descriptor: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | Authors: | Sanz-Murillo, M, Xu, J, Gil-Carton, D, Wang, D, Fernandez-Tornero, C. | Deposit date: | 2018-07-26 | Release date: | 2018-08-29 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural basis of RNA polymerase I stalling at UV light-induced DNA damage. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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4N3M
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![BU of 4n3m by Molmil](/molmil-images/mine/4n3m) | Joint neutron/X-ray structure of urate oxidase in complex with 8-azaxanthine | Descriptor: | 8-AZAXANTHINE, CHLORIDE ION, SODIUM ION, ... | Authors: | Oksanen, E, Blakeley, M.P, Budayova-Spano, M. | Deposit date: | 2013-10-07 | Release date: | 2014-02-05 | Last modified: | 2018-06-13 | Method: | NEUTRON DIFFRACTION (1.919 Å), X-RAY DIFFRACTION | Cite: | The neutron structure of urate oxidase resolves a long-standing mechanistic conundrum and reveals unexpected changes in protonation. Plos One, 9, 2014
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