4C9Q
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![BU of 4c9q by Molmil](/molmil-images/mine/4c9q) | Structure of yeast mitochondrial ADP/ATP carrier isoform 3 inhibited by carboxyatractyloside (P21 crystal form) | Descriptor: | ADP, ATP CARRIER PROTEIN 3, CARDIOLIPIN, ... | Authors: | Ruprecht, J.J, Hellawell, A.M, Harding, M, Crichton, P.G, McCoy, A.J, Kunji, E.R.S. | Deposit date: | 2013-10-02 | Release date: | 2014-01-22 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structures of Yeast Mitochondrial Adp/ATP Carriers Support a Domain-Based Alternating-Access Transport Mechanism Proc.Natl.Acad.Sci.USA, 111, 2014
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2K28
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![BU of 2k28 by Molmil](/molmil-images/mine/2k28) | Solution NMR structure of the chromo domain of the chromobox protein homolog 4 | Descriptor: | E3 SUMO-protein ligase CBX4 | Authors: | Kaustov, L, Lemak, A, Quyang, H, Fares, C, Gutmanas, A, Ravichandran, M, Loppnau, P, Bountra, C, Weigelt, J, Edwards, A.M, Min, J, Arrowsmith, C.H, Structural Genomics Consortium (SGC) | Deposit date: | 2008-03-27 | Release date: | 2008-04-08 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of the chromo domain of the chromobox protein homolog 4. To be Published
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4BWQ
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![BU of 4bwq by Molmil](/molmil-images/mine/4bwq) | Crystal structure of U5-15kD in a complex with PQBP1 | Descriptor: | POLYGLUTAMINE-BINDING PROTEIN 1, THIOREDOXIN-LIKE PROTEIN 4A | Authors: | Mizuguchi, M, Obita, T, Serita, T, Kojima, R, Morimoto, T, Nabeshima, Y, Okazawa, H. | Deposit date: | 2013-07-04 | Release date: | 2014-04-30 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Mutations in the Pqbp1 Gene Prevent its Interaction with the Spliceosomal Protein U5-15Kd. Nat.Commun., 5, 2014
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1NCT
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![BU of 1nct by Molmil](/molmil-images/mine/1nct) | TITIN MODULE M5, N-TERMINALLY EXTENDED, NMR | Descriptor: | TITIN | Authors: | Pfuhl, M, Pastore, A. | Deposit date: | 1996-08-13 | Release date: | 1996-11-08 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | When a module is also a domain: the role of the N terminus in the stability and the dynamics of immunoglobulin domains from titin. J.Mol.Biol., 265, 1997
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3ZOR
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![BU of 3zor by Molmil](/molmil-images/mine/3zor) | Structure of BsUDG | Descriptor: | URACIL-DNA GLYCOSYLASE | Authors: | Banos-Sanz, J.I, Mojardin, L, Sanz-Aparicio, J, Gonzalez, B, Salas, M. | Deposit date: | 2013-02-22 | Release date: | 2013-05-22 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Crystal Structure and Functional Insights Into Uracil-DNA Glycosylase Inhibition by Phage Phi29 DNA Mimic Protein P56 Nucleic Acids Res., 41, 2013
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2JJC
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![BU of 2jjc by Molmil](/molmil-images/mine/2jjc) | Hsp90 alpha ATPase domain with bound small molecule fragment | Descriptor: | DIMETHYL SULFOXIDE, HEAT SHOCK PROTEIN HSP 90-ALPHA, PYRIMIDIN-2-AMINE | Authors: | Congreve, M, Chessari, G, Tisi, D, Woodhead, A.J. | Deposit date: | 2008-03-31 | Release date: | 2008-07-15 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Recent Developments in Fragment-Based Drug Discovery. J.Med.Chem., 51, 2008
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3ZOX
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![BU of 3zox by Molmil](/molmil-images/mine/3zox) | Crystal Structure of N64Del Mutant of Nitrosomonas europaea Cytochrome c552 (monoclinic space group) | Descriptor: | CYTOCHROME C-552, HEME C | Authors: | Hersleth, H.-P, Can, M, Krucinska, J, Zoppellaro, G, Andersen, N.H, Wedekind, J.E, Andersson, K.K, Bren, K.L. | Deposit date: | 2013-02-26 | Release date: | 2013-08-14 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural Characterization of Nitrosomonas Europaea Cytochrome C-552 Variants with Marked Differences in Electronic Structure. Chembiochem, 14, 2013
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2JSB
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![BU of 2jsb by Molmil](/molmil-images/mine/2jsb) | Solution structure of arenicin-1 | Descriptor: | Arenicin-1 | Authors: | Jakovkin, I.B, Hecht, O, Gelhaus, C, Krasnosdembskaya, A.D, Fedders, H, Leippe, M, Groetzinger, J. | Deposit date: | 2007-07-02 | Release date: | 2008-02-05 | Last modified: | 2020-02-19 | Method: | SOLUTION NMR | Cite: | Structure and mode of action of the antimicrobial peptide arenicin Biochem.J., 410, 2008
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2JLL
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![BU of 2jll by Molmil](/molmil-images/mine/2jll) | Crystal structure of NCAM2 IgIV-FN3II | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ... | Authors: | Kulahin, N, Rasmussen, K, Kristensen, O, Kastrup, J, Berezin, V, Bock, E, Walmod, P, Gajhede, M. | Deposit date: | 2008-09-10 | Release date: | 2009-11-17 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural Model and Trans-Interaction of the Entire Ectodomain of the Olfactory Cell Adhesion Molecule. Structure, 19, 2011
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3ZUI
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![BU of 3zui by Molmil](/molmil-images/mine/3zui) | OMCI in complex with palmitoleic acid | Descriptor: | COMPLEMENT INHIBITOR, PALMITOLEIC ACID | Authors: | Roversi, P, Maillet, I, Togbe, D, Couillin, I, Quesniaux, V.F.J, Teixeira, M, Ahmat, N, Lissina, O, Boland, W, Ploss, K, Caesar, J.J.E, Leonhartsberger, S, Ryffel, B, Lea, S.M, Nunn, M.A. | Deposit date: | 2011-07-19 | Release date: | 2012-08-01 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | Bifunctional Lipocalin Ameliorates Murine Immune Complex-Induced Acute Lung Injury. J.Biol.Chem., 288, 2013
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3ZXD
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![BU of 3zxd by Molmil](/molmil-images/mine/3zxd) | wild-type lysenin | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, GLYCEROL, ... | Authors: | De Colibus, L, Sonnen, A.F.P, Morris, K.J, Siebert, C.A, Abrusci, P, Plitzko, J, Hodnik, V, Leippe, M, Volpi, E, Anderluh, G, Gilbert, R.J.C. | Deposit date: | 2011-08-09 | Release date: | 2012-09-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structures of Lysenin Reveal a Shared Evolutionary Origin for Pore-Forming Proteins and its Mode of Sphingomyelin Recognition. Structure, 20, 2012
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2JTW
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![BU of 2jtw by Molmil](/molmil-images/mine/2jtw) | |
3ZY6
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![BU of 3zy6 by Molmil](/molmil-images/mine/3zy6) | Crystal structure of POFUT1 in complex with GDP-fucose (crystal-form-II) | Descriptor: | GUANOSINE-5'-DIPHOSPHATE-BETA-L-FUCOPYRANOSE, PUTATIVE GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 1 | Authors: | Lira-Navarrete, E, Valero-Gonzalez, J, Villanueva, R, Martinez-Julvez, M, Tejero, T, Merino, P, Panjikar, S, Hurtado-Guerrero, R. | Deposit date: | 2011-08-17 | Release date: | 2011-09-14 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Structural Insights Into the Mechanism of Protein O-Fucosylation. Plos One, 6, 2011
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2K49
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![BU of 2k49 by Molmil](/molmil-images/mine/2k49) | Solution NMR structure of UPF0339 protein SO3888 from Shewanella oneidensis. Northeast Structural Genomics Consortium target SoR190 | Descriptor: | UPF0339 protein SO_3888 | Authors: | Tang, Y, Wang, D, Nwosu, C, Maglaqui, M, Xiao, R, Liu, J, Baran, M.C, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2008-05-31 | Release date: | 2008-07-08 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of UPF0339 protein SO3888 from Shewanella oneidensis. To be Published
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4GV1
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![BU of 4gv1 by Molmil](/molmil-images/mine/4gv1) | PKB alpha in complex with AZD5363 | Descriptor: | 4-amino-N-[(1S)-1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide, GLYCEROL, RAC-alpha serine/threonine-protein kinase | Authors: | Addie, M, Ballard, P, Bird, G, Buttar, D, Currie, G, Davies, B, Debreczeni, J, Dry, H, Dudley, P, Greenwood, R, Hatter, G, Jestel, A, Johnson, P.D, Kettle, J.G, Lane, C, Lamont, G, Leach, A, Luke, R.W.A, Ogilvie, D, Page, K, Pass, M, Steinbacher, S, Steuber, H, Pearson, S, Ruston, L. | Deposit date: | 2012-08-30 | Release date: | 2013-02-27 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | Discovery of 4-Amino-N-[(1S)-1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide (AZD5363), an Orally Bioavailable, Potent Inhibitor of Akt Kinases. J.Med.Chem., 56, 2013
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3ZZJ
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![BU of 3zzj by Molmil](/molmil-images/mine/3zzj) | Structure of an engineered aspartate aminotransferase | Descriptor: | ASPARTATE AMINOTRANSFERASE, BETA-MERCAPTOETHANOL, DI(HYDROXYETHYL)ETHER, ... | Authors: | Fernandez, F.J, deVries, D, Pena-Soler, E, Coll, M, Christen, P, Gehring, H, Vega, M.C. | Deposit date: | 2011-09-01 | Release date: | 2011-12-28 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure and Mechanism of a Cysteine Sulfinate Desulfinase Engineered on the Aspartate Aminotransferase Scaffold. Biocim.Biophys.Acta, 1824, 2011
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3ZV9
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![BU of 3zv9 by Molmil](/molmil-images/mine/3zv9) | 3C protease of Enterovirus 68 complexed with Michael receptor inhibitor 74 | Descriptor: | 3C PROTEASE, ETHYL (4R)-4-[(TERT-BUTOXYCARBONYL)AMINO]-5-[(3S)-2-OXOPYRROLIDIN-3-YL]PENTANOATE | Authors: | Tan, J, Perbandt, M, Mesters, J.R, Hilgenfeld, R. | Deposit date: | 2011-07-24 | Release date: | 2012-08-08 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | 3C Protease of Enterovirus 68: Structure-Based Design of Michael Acceptor Inhibitors and Their Broad-Spectrum Antiviral Effects Against Picornaviruses. J.Virol., 87, 2013
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2JRL
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![BU of 2jrl by Molmil](/molmil-images/mine/2jrl) | Solution structure of the beryllofluoride-activated NtrC4 receiver domain dimer | Descriptor: | Transcriptional regulator (NtrC family) | Authors: | Lee, C, Hong, E, Doucleff, M, Pelton, J.G, Wemmer, D.E, Berkeley Structural Genomics Center (BSGC) | Deposit date: | 2007-06-27 | Release date: | 2008-07-01 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution Structure of the Beryllofluoride-Activated NtrC4 Receiver Domain Dimer. To be Published
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3ZWP
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![BU of 3zwp by Molmil](/molmil-images/mine/3zwp) | Crystal structure of ADP ribosyl cyclase complexed with ara-2'F-ADP- ribose at 2.1 angstrom | Descriptor: | ADP-RIBOSYL CYCLASE, GLYCEROL, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl [(2R,3R,4R)-4-fluoro-3-hydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate | Authors: | Kotaka, M, Graeff, R, Zhang, L.H, Lee, H.C, Hao, Q. | Deposit date: | 2011-08-02 | Release date: | 2011-11-30 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | Structural Studies of Intermediates Along the Cyclization Pathway of Aplysia Adp-Ribosyl Cyclase. J.Mol.Biol., 415, 2012
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3ZUO
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![BU of 3zuo by Molmil](/molmil-images/mine/3zuo) | OMCI in complex with leukotriene B4 | Descriptor: | COMPLEMENT INHIBITOR, LEUKOTRIENE B4 | Authors: | Roversi, P, Maillet, I, Togbe, D, Couillin, I, Quesniaux, V.F.J, Teixeira, M, Ahmat, N, Lissina, O, Boland, W, Ploss, K, Caesar, J.J.E, Leonhartsberger, S, Ryffel, B, Lea, S.M, Nunn, M.A. | Deposit date: | 2011-07-19 | Release date: | 2012-08-01 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Bifunctional Lipocalin Ameliorates Murine Immune Complex-Induced Acute Lung Injury. J.Biol.Chem., 288, 2013
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2VKQ
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![BU of 2vkq by Molmil](/molmil-images/mine/2vkq) | Crystal structure of human cytosolic 5'-nucleotidase III (cN-III, NT5C3) in complex with beryllium trifluoride | Descriptor: | BERYLLIUM TRIFLUORIDE ION, CYTOSOLIC 5'-NUCLEOTIDASE III, MAGNESIUM ION | Authors: | Wallden, K, Moche, M, Arrowsmith, C.H, Berglund, H, Busam, R, Collins, R, Dahlgren, L.G, Edwards, A, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Herman, M.D, Johansson, A, Johansson, I, Kallas, A, Karlberg, T, Kotenyova, T, Lehtio, L, Nilsson, M.E, Nyman, T, Persson, C, Sagemark, J, Thorsell, A.G, Tresaugues, L, van den Berg, S, Weigelt, J, Welin, M, Nordlund, P, Structural Genomics Consortium (SGC) | Deposit date: | 2007-12-21 | Release date: | 2008-01-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal Structure of Human Cytosolic 5'- Nucleotidase III To be Published
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3ZHV
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![BU of 3zhv by Molmil](/molmil-images/mine/3zhv) | Crystal structure of the SucA domain of Mycobacterium smegmatis KGD, post-decarboxylation intermediate from pyruvate (2-hydroxyethyl-ThDP) | Descriptor: | 2-[3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-2-[(1S)-1-oxidanylethyl]-1,3-thiazol-3-ium-5-yl]ethyl phosphono hydrogen phosphate, CALCIUM ION, MAGNESIUM ION, ... | Authors: | Wagner, T, Barilone, N, Bellinzoni, M, Alzari, P.M. | Deposit date: | 2012-12-24 | Release date: | 2013-11-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | A Dual Conformation of the Post-Decarboxylation Intermediate is Associated with Distinct Enzyme States in Mycobacterial Alpha-Ketoglutarate Decarboxylase (Kgd). Biochem.J., 457, 2014
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3ZZ0
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![BU of 3zz0 by Molmil](/molmil-images/mine/3zz0) | |
3ZXL
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![BU of 3zxl by Molmil](/molmil-images/mine/3zxl) | Engineering the active site of a GH43 glycoside hydrolase generates a biotechnologically significant enzyme that displays both endo- xylanase and exo-arabinofuranosidase activity | Descriptor: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, HIAXHD3 | Authors: | McKee, L.S, Pena, M.J, Rogowski, A, Jackson, A, Lewis, R.J, York, W.S, Krogh, K.B.R.M, Vikso-Nielsen, A, Skjot, M, Gilbert, H.J, Marles-Wright, J. | Deposit date: | 2011-08-11 | Release date: | 2012-04-18 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.871 Å) | Cite: | Introducing Endo-Xylanase Activity Into an Exo-Acting Arabinofuranosidase that Targets Side Chains. Proc.Natl.Acad.Sci.USA, 109, 2012
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2NNY
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![BU of 2nny by Molmil](/molmil-images/mine/2nny) | Crystal structure of the Ets1 dimer DNA complex. | Descriptor: | 5'-D(*A*CP*TP*CP*CP*AP*GP*GP*AP*AP*GP*TP*GP*CP*TP*TP*CP*CP*TP*GP*TP*CP*T)-3', 5'-D(*T*AP*GP*AP*CP*AP*GP*GP*AP*AP*GP*CP*AP*CP*TP*TP*CP*CP*TP*GP*GP*AP*G)-3', C-ets-1 protein | Authors: | Lamber, E.P, Kachalova, G.S, Wilmanns, M. | Deposit date: | 2006-10-24 | Release date: | 2008-03-04 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.58 Å) | Cite: | Regulation of the transcription factor Ets-1 by DNA-mediated homo-dimerization. Embo J., 27, 2008
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