5CFI
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6HZ0
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![BU of 6hz0 by Molmil](/molmil-images/mine/6hz0) | THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT K248A | Descriptor: | ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ... | Authors: | Hu, H.D, Delarue, M. | Deposit date: | 2018-10-22 | Release date: | 2018-12-19 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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2DXS
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![BU of 2dxs by Molmil](/molmil-images/mine/2dxs) | Crystal structure of HCV NS5B RNA polymerase complexed with a tetracyclic inhibitor | Descriptor: | Genome polyprotein, N-[(13-CYCLOHEXYL-6,7-DIHYDROINDOLO[1,2-D][1,4]BENZOXAZEPIN-10-YL)CARBONYL]-2-METHYL-L-ALANINE | Authors: | Adachi, T, Tsuruha, J, Doi, S, Murase, K, Ikegashira, K, Watanabe, S, Uehara, K, Orita, T, Nomura, A, Kamada, M. | Deposit date: | 2006-08-30 | Release date: | 2006-12-26 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Discovery of Conformationally Constrained Tetracyclic Compounds as Potent Hepatitis C Virus NS5B RNA Polymerase Inhibitors J.Med.Chem., 49, 2006
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6HZW
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![BU of 6hzw by Molmil](/molmil-images/mine/6hzw) | THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL 2.22 resolution | Descriptor: | ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ... | Authors: | Hu, H.D, Delarue, M. | Deposit date: | 2018-10-24 | Release date: | 2018-12-19 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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3OFM
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![BU of 3ofm by Molmil](/molmil-images/mine/3ofm) | Structure of a human CK2alpha prime, the paralog isoform of the catalytic subunit of protein kinase CK2 from Homo sapiens | Descriptor: | 3-(4,5,6,7-tetrabromo-1H-benzotriazol-1-yl)propan-1-ol, CHLORIDE ION, Casein kinase II subunit alpha' | Authors: | Bischoff, N, Olsen, B, Raaf, J, Bretner, M, Issinger, O.-G, Niefind, K. | Deposit date: | 2010-08-15 | Release date: | 2011-01-19 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis of the reduced affinity between the protein kinase CK2 subunits CK2alpha prime and CK2beta J.Mol.Biol., 407, 2011
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6GE7
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4LJD
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![BU of 4ljd by Molmil](/molmil-images/mine/4ljd) | Structure of a photobleached state of IrisFP under low intensity laser-light | Descriptor: | Green to red photoconvertible GPF-like protein EosFP, SULFATE ION, SULFITE ION | Authors: | Duan, C, Adam, V, Byrdin, M, Ridard, J, Kieffer-Jacquinod, S, Morlot, C, Arcizet, D, Demachy, I, Bourgeois, D. | Deposit date: | 2013-07-04 | Release date: | 2013-10-09 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural evidence for a two-regime photobleaching mechanism in a reversibly switchable fluorescent protein. J.Am.Chem.Soc., 135, 2013
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1L96
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![BU of 1l96 by Molmil](/molmil-images/mine/1l96) | STRUCTURE OF A HINGE-BENDING BACTERIOPHAGE T4 LYSOZYME MUTANT, ILE3-> PRO | Descriptor: | BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME | Authors: | Dixon, M, Shewchuk, L, Matthews, B.W. | Deposit date: | 1992-02-11 | Release date: | 1993-10-31 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of a hinge-bending bacteriophage T4 lysozyme mutant, Ile3-->Pro. J.Mol.Biol., 227, 1992
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3OG2
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![BU of 3og2 by Molmil](/molmil-images/mine/3og2) | Native crystal structure of Trichoderma reesei beta-galactosidase | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-galactosidase, ... | Authors: | Maksimainen, M, Rouvinen, J. | Deposit date: | 2010-08-16 | Release date: | 2011-03-16 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Crystal structures of Trichoderma reesei beta-galactosidase reveal conformational changes in the active site J.Struct.Biol., 174, 2011
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8AXC
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![BU of 8axc by Molmil](/molmil-images/mine/8axc) | Crystal structure of mouse Ces2c | Descriptor: | Acylcarnitine hydrolase, CHLORIDE ION, NICOTINAMIDE, ... | Authors: | Eisner, H, Riegler-Berket, L, Rodriguez Gamez, C, Sagmeister, T, Chalhoub, G, Darnhofer, B, Panikkaveetil Jawaharlal, J, Birner-Gruenberger, R, Pavkov-Keller, T, Haemmerle, G, Schoiswohl, G, Oberer, M. | Deposit date: | 2022-08-31 | Release date: | 2022-11-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.12 Å) | Cite: | The Crystal Structure of Mouse Ces2c, a Potential Ortholog of Human CES2, Shows Structural Similarities in Substrate Regulation and Product Release to Human CES1. Int J Mol Sci, 23, 2022
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6G10
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6I0U
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![BU of 6i0u by Molmil](/molmil-images/mine/6i0u) | Crystal structure of DmTailor in complex with U6 RNA | Descriptor: | MAGNESIUM ION, RNA (5'-R(*UP*UP*UP*U)-3'), Terminal uridylyltransferase Tailor | Authors: | Kroupova, A, Ivascu, A, Jinek, M. | Deposit date: | 2018-10-26 | Release date: | 2018-12-05 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.001 Å) | Cite: | Structural basis for acceptor RNA substrate selectivity of the 3' terminal uridylyl transferase Tailor. Nucleic Acids Res., 47, 2019
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6HL1
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![BU of 6hl1 by Molmil](/molmil-images/mine/6hl1) | Crystal Structure of Farnesoid X receptor (FXR) with bound NCoA-2 peptide and CDCA | Descriptor: | Bile acid receptor, CHENODEOXYCHOLIC ACID, NCoA-2 peptide (Nuclear receptor coactivator 2), ... | Authors: | Kudlinzki, D, Merk, D, Linhard, V.L, Saxena, K, Schubert-Zsilavecz, M, Schwalbe, H. | Deposit date: | 2018-09-10 | Release date: | 2019-05-29 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.599 Å) | Cite: | Molecular tuning of farnesoid X receptor partial agonism. Nat Commun, 10, 2019
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3K2I
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![BU of 3k2i by Molmil](/molmil-images/mine/3k2i) | Human Acyl-coenzyme A thioesterase 4 | Descriptor: | Acyl-coenzyme A thioesterase 4, CHLORIDE ION, NICKEL (II) ION | Authors: | Siponen, M.I, Moche, M, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Karlberg, T, Kraulis, P, Kotenyova, T, Kotzsch, A, Markova, N, Nielsen, T.K, Nordlund, P, Nyman, T, Persson, C, Roos, A.K, Schutz, P, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Wahlberg, E, Weigelt, J, Welin, M, Wisniewska, M, Schuler, H, Structural Genomics Consortium (SGC) | Deposit date: | 2009-09-30 | Release date: | 2009-10-20 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Human Acyl-coenzyme A thioesterase 4 To be Published
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1LK0
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![BU of 1lk0 by Molmil](/molmil-images/mine/1lk0) | Disulfide intermediate of C89L Arsenate reductase from pI258 | Descriptor: | CHLORIDE ION, POTASSIUM ION, arsenate reductase | Authors: | Messens, J, Martins, J.C, Van Belle, K, Brosens, E, Desmyter, A, De Gieter, M, Wieruszeski, J.M, Willem, R, Wyns, L, Zegers, I. | Deposit date: | 2002-04-23 | Release date: | 2002-08-07 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | All intermediates of the arsenate reductase mechanism, including an intramolecular dynamic disulfide cascade. Proc.Natl.Acad.Sci.USA, 99, 2002
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3OGV
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![BU of 3ogv by Molmil](/molmil-images/mine/3ogv) | Complex structure of beta-galactosidase from Trichoderma reesei with PETG | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-phenylethyl 1-thio-beta-D-galactopyranoside, ... | Authors: | Maksimainen, M, Rouvinen, J. | Deposit date: | 2010-08-17 | Release date: | 2011-03-16 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Crystal structures of Trichoderma reesei beta-galactosidase reveal conformational changes in the active site J.Struct.Biol., 174, 2011
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6G18
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![BU of 6g18 by Molmil](/molmil-images/mine/6g18) | Cryo-EM structure of a late human pre-40S ribosomal subunit - State C | Descriptor: | 40S ribosomal protein S11, 40S ribosomal protein S12, 40S ribosomal protein S13, ... | Authors: | Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. | Deposit date: | 2018-03-20 | Release date: | 2018-06-06 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Visualizing late states of human 40S ribosomal subunit maturation. Nature, 558, 2018
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6HLL
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![BU of 6hll by Molmil](/molmil-images/mine/6hll) | Crystal structure of the Neurokinin 1 receptor in complex with the small molecule antagonist CP-99,994 | Descriptor: | (2~{S},3~{S})-~{N}-[(2-methoxyphenyl)methyl]-2-phenyl-piperidin-3-amine, Substance-P receptor,GlgA glycogen synthase,Substance-P receptor | Authors: | Schoppe, J, Ehrenmann, J, Klenk, C, Rucktooa, P, Schutz, M, Dore, A.S, Pluckthun, A. | Deposit date: | 2018-09-11 | Release date: | 2019-01-16 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.27 Å) | Cite: | Crystal structures of the human neurokinin 1 receptor in complex with clinically used antagonists. Nat Commun, 10, 2019
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3OD9
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![BU of 3od9 by Molmil](/molmil-images/mine/3od9) | Crystal structure of PliI-Ah, periplasmic lysozyme inhibitor of I-type lysozyme from Aeromonas hydrophyla | Descriptor: | POTASSIUM ION, Putative exported protein, SODIUM ION | Authors: | Leysen, S, Van Herreweghe, J.M, Callewaert, L, Heirbaut, M, Buntinx, P, Michiels, C.W, Strelkov, S.V. | Deposit date: | 2010-08-11 | Release date: | 2010-12-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.411 Å) | Cite: | Molecular Basis of Bacterial Defense against Host Lysozymes: X-ray Structures of Periplasmic Lysozyme Inhibitors PliI and PliC. J.Mol.Biol., 405, 2011
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6G4A
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![BU of 6g4a by Molmil](/molmil-images/mine/6g4a) | FLN5 (full length) | Descriptor: | Gelation factor | Authors: | Waudby, C.A, Wlodarski, T, Karyadi, M.-E, Cassaignau, A.M.E, Chan, S.H.S, Wentink, A.S, Schmidt-Engler, J.M, Camilloni, C, Vendruscolo, M, Cabrita, L.D, Christodoulou, J. | Deposit date: | 2018-03-27 | Release date: | 2019-04-10 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Mapping energy landscapes of a growing filamin domain reveals an intermediate associated with proline isomerization during biosynthesis To Be Published
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4YSZ
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![BU of 4ysz by Molmil](/molmil-images/mine/4ysz) | Crystal structure of Mitochondrial rhodoquinol-fumarate reductase from Ascaris suum with 2-iodo-N-[3-(1-methylethoxy)phenyl]benzamide | Descriptor: | 2-iodo-N-[3-(1-methylethoxy)phenyl]benzamide, Cytochrome b-large subunit, FE2/S2 (INORGANIC) CLUSTER, ... | Authors: | Harada, S, Shiba, T, Sato, D, Yamamoto, A, Nagahama, M, Yone, A, Inaoka, D.K, Sakamoto, K, Inoue, M, Honma, T, Kita, K. | Deposit date: | 2015-03-17 | Release date: | 2015-08-05 | Last modified: | 2020-02-05 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria Int J Mol Sci, 16, 2015
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1LKZ
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![BU of 1lkz by Molmil](/molmil-images/mine/1lkz) | Crystal structure of D-ribose-5-phosphate isomerase (RpiA) from Escherichia coli. | Descriptor: | Ribose 5-phosphate isomerase A | Authors: | Rangarajan, E.S, Sivaraman, J, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | Deposit date: | 2002-04-26 | Release date: | 2002-05-08 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of D-ribose-5-phosphate isomerase (RpiA) from Escherichia coli Proteins, 48, 2002
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4LNV
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![BU of 4lnv by Molmil](/molmil-images/mine/4lnv) | Crystal Structure of TEP1s | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Thioester-containing protein I | Authors: | Le, B.V, Williams, M, Logarajah, S, Baxter, R.H.G. | Deposit date: | 2013-07-12 | Release date: | 2013-07-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | Molecular basis for genetic resistance of Anopheles gambiae to Plasmodium: structural analysis of TEP1 susceptible and resistant alleles. Plos Pathog., 8, 2012
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6HM9
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1LLT
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![BU of 1llt by Molmil](/molmil-images/mine/1llt) | BIRCH POLLEN ALLERGEN BET V 1 MUTANT E45S | Descriptor: | POLLEN ALLERGEN BET V 1 | Authors: | Spangfort, M.D, Mirza, O, Ipsen, H, Van Neerven, R.J, Gajhede, M, Larsen, J.N. | Deposit date: | 2002-04-30 | Release date: | 2003-10-28 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Dominating IgE-binding epitope of Bet v 1, the major allergen of birch pollen, characterized by X-ray crystallography and site-directed mutagenesis. J.Immunol., 171, 2003
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