8AXC
Crystal structure of mouse Ces2c
Summary for 8AXC
Entry DOI | 10.2210/pdb8axc/pdb |
Descriptor | Acylcarnitine hydrolase, CHLORIDE ION, NICOTINAMIDE, ... (5 entities in total) |
Functional Keywords | carboxylesterase 2c; protein structure; lipid metabolism; x-ray crystallography; alpha/beta-hydrolase fold; biochemistry; lipid hydrolysis; non-alcoholic fatty liver disease; molnupiravir, hydrolase |
Biological source | Mus musculus (house mouse) |
Total number of polymer chains | 4 |
Total formula weight | 251099.98 |
Authors | Eisner, H.,Riegler-Berket, L.,Rodriguez Gamez, C.,Sagmeister, T.,Chalhoub, G.,Darnhofer, B.,Panikkaveetil Jawaharlal, J.,Birner-Gruenberger, R.,Pavkov-Keller, T.,Haemmerle, G.,Schoiswohl, G.,Oberer, M. (deposition date: 2022-08-31, release date: 2022-11-16, Last modification date: 2024-01-31) |
Primary citation | Eisner, H.,Riegler-Berket, L.,Gamez, C.F.R.,Sagmeister, T.,Chalhoub, G.,Darnhofer, B.,Jazleena, P.J.,Birner-Gruenberger, R.,Pavkov-Keller, T.,Haemmerle, G.,Schoiswohl, G.,Oberer, M. The Crystal Structure of Mouse Ces2c, a Potential Ortholog of Human CES2, Shows Structural Similarities in Substrate Regulation and Product Release to Human CES1. Int J Mol Sci, 23:-, 2022 Cited by PubMed: 36361897DOI: 10.3390/ijms232113101 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.12 Å) |
Structure validation
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