6O9B
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8QWA
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![BU of 8qwa by Molmil](/molmil-images/mine/8qwa) | Adenylosuccinate Synthetase from H. pylori in complex with PLP and IMP | Descriptor: | Adenylosuccinate synthetase, GLYCEROL, INOSINIC ACID, ... | Authors: | Bzowska, A, Narczyk, M, Maksymiuk, W. | Deposit date: | 2023-10-19 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Vitamin B6 inhibits activity of Helicobacter pylori adenylosuccinate synthetase and growth of reference and clinical, antibiotic-resistant H. pylori strains. J Enzyme Inhib Med Chem, 39, 2024
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8B5X
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![BU of 8b5x by Molmil](/molmil-images/mine/8b5x) | Crystal structure of the SUN1-KASH6 9:6 complex | Descriptor: | CHLORIDE ION, Inositol 1,4,5-triphosphate receptor associated 2, POTASSIUM ION, ... | Authors: | Erlandsen, B.S, Gurusaran, M, Davies, O.R. | Deposit date: | 2022-09-25 | Release date: | 2023-10-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | The crystal structure of SUN1-KASH6 reveals an asymmetric LINC complex architecture compatible with nuclear membrane insertion. Commun Biol, 7, 2024
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8RJJ
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![BU of 8rjj by Molmil](/molmil-images/mine/8rjj) | HCV E1/E2 homodimer complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Genome polyprotein, ... | Authors: | Augestad, E.H, Olesen, C.H, Groenberg, C, Soerensen, A, Velazquez-Moctezuma, R, Fanalista, M, Bukh, J, Wang, K, Gourdon, P, Prentoe, J. | Deposit date: | 2023-12-21 | Release date: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (3.55 Å) | Cite: | The hepatitis C virus envelope protein complex is a dimer of heterodimers Nature, 2024
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8RK0
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![BU of 8rk0 by Molmil](/molmil-images/mine/8rk0) | HCV E1/E2 homodimer complex, ectodomain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HCV E1, ... | Authors: | Augestad, E.H, Olesen, C.H, Groenberg, C, Soerensen, A, Velazquez-Moctezuma, R, Fanalista, M, Bukh, J, Wang, K, Gourdon, P, Prentoe, J. | Deposit date: | 2023-12-22 | Release date: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (3.38 Å) | Cite: | The hepatitis C virus envelope protein complex is a dimer of heterodimers Nature, 2024
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8B87
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8B9N
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8TW8
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![BU of 8tw8 by Molmil](/molmil-images/mine/8tw8) | Cryo-EM structure of S. cerevisiae Ctf18-RFC-PCNA complex in Apo state conformation I | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Chromosome transmission fidelity protein 18, MAGNESIUM ION, ... | Authors: | Yuan, Z, Georgescu, R, O'Donnell, M, Li, H. | Deposit date: | 2023-08-20 | Release date: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Cryo-EM reveals that Ctf18-RFC collaborates with PolE to load the PCNA clamp onto a leading strand DNA To Be Published
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8B9T
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8TW7
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![BU of 8tw7 by Molmil](/molmil-images/mine/8tw7) | Cryo-EM structure of S. cerevisiae Ctf18-RFC-PCNA complex in Apo state conformation I | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Chromosome transmission fidelity protein 18, MAGNESIUM ION, ... | Authors: | Yuan, Z, Georgescu, R, O'Donnell, M, Li, H. | Deposit date: | 2023-08-20 | Release date: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Cryo-EM reveals that Ctf18-RFC collaborates with PolE to load the PCNA clamp onto a leading strand DNA To Be Published
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8TWB
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![BU of 8twb by Molmil](/molmil-images/mine/8twb) | Cryo-EM structure of S. cerevisiae Ctf18-RFC-PCNA-DNA complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Chromosome transmission fidelity protein 18, MAGNESIUM ION, ... | Authors: | Yuan, Z, Georgescu, R, O'Donnell, M, Li, H. | Deposit date: | 2023-08-20 | Release date: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM reveals that Ctf18-RFC collaborates with PolE to load the PCNA clamp onto a leading strand DNA To Be Published
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8B82
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5SBD
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![BU of 5sbd by Molmil](/molmil-images/mine/5sbd) | Tubulin-maytansinoid-5b-complex | Descriptor: | (1S,2R,3S,5S,6S,16E,18E,20R)-11-chloro-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.1~10,14~.0~3,5~]hexacosa-10(26),11,13,16,18,21(25)-hexaen-6-yl acetate, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | Authors: | Marzullo, P, Boiarska, Z, Perez-Pena, H, Abel, A.-C, Alvarez-Bernad, B, Lucena-Agell, D, Vasile, F, Sironi, M, Steinmetz, M.O, Prota, A.E, Diaz, J.F, Pieraccini, S, Passarella, D. | Deposit date: | 2021-07-20 | Release date: | 2021-12-08 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Maytansinol Derivatives: Side Reactions as a Chance for New Tubulin Binders. Chemistry, 28, 2022
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8B8O
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5SBA
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![BU of 5sba by Molmil](/molmil-images/mine/5sba) | Tubulin-maytansinoid-4b-complex | Descriptor: | (1S,2R,3S,5S,6S,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.1~10,14~.0~3,5~]hexacosa-10(26),11,13,16,18-pentaen-6-yl acetate, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | Authors: | Marzullo, P, Boiarska, Z, Perez-Pena, H, Abel, A.-C, Alvarez-Bernad, B, Lucena-Agell, D, Vasile, F, Sironi, M, Steinmetz, M.O, Prota, A.E, Diaz, J.F, Pieraccini, S, Passarella, D. | Deposit date: | 2021-07-20 | Release date: | 2021-12-08 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Maytansinol Derivatives: Side Reactions as a Chance for New Tubulin Binders. Chemistry, 28, 2022
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5HQF
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![BU of 5hqf by Molmil](/molmil-images/mine/5hqf) | DNA duplex containing a ribonolactone lesion | Descriptor: | DNA (5'-D(*CP*GP*CP*TP*CP*(RIB)P*CP*AP*CP*GP*C)-3'), DNA (5'-D(*GP*CP*GP*TP*GP*GP*GP*AP*(8OG)P*CP*G)-3') | Authors: | Zalesak, J, Constant, J.F, Jourdan, M. | Deposit date: | 2016-01-21 | Release date: | 2016-09-14 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Nuclear Magnetic Resonance Solution Structure of DNA Featuring Clustered 2'-Deoxyribonolactone and 8-Oxoguanine Lesions. Biochemistry, 55, 2016
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8BL3
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5SBE
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![BU of 5sbe by Molmil](/molmil-images/mine/5sbe) | Tubulin-maytansinoid-5c-complex | Descriptor: | (1S,2R,3S,5S,6S,16E,18E,20R)-11-chloro-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.1~10,14~.0~3,5~]hexacosa-10(26),11,13,16,18,21-hexaen-6-yl hept-6-ynoate, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | Authors: | Marzullo, P, Boiarska, Z, Perez-Pena, H, Abel, A.-C, Alvarez-Bernad, B, Lucena-Agell, D, Vasile, F, Sironi, M, Steinmetz, M.O, Prota, A.E, Diaz, J.F, Pieraccini, S, Passarella, D. | Deposit date: | 2021-07-20 | Release date: | 2021-12-08 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Maytansinol Derivatives: Side Reactions as a Chance for New Tubulin Binders. Chemistry, 28, 2022
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5SBB
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![BU of 5sbb by Molmil](/molmil-images/mine/5sbb) | Tubulin-maytansinoid-4c-complex | Descriptor: | (1R,2R,3S,5S,6S,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.1~10,14~.0~3,5~]hexacosa-10(26),11,13,16,18-pentaen-6-yl heptanoate, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | Authors: | Marzullo, P, Boiarska, Z, Perez-Pena, H, Abel, A.-C, Alvarez-Bernad, B, Lucena-Agell, D, Vasile, F, Sironi, M, Steinmetz, M.O, Prota, A.E, Diaz, J.F, Pieraccini, S, Passarella, D. | Deposit date: | 2021-07-20 | Release date: | 2021-12-08 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Maytansinol Derivatives: Side Reactions as a Chance for New Tubulin Binders. Chemistry, 28, 2022
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4JJ0
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![BU of 4jj0 by Molmil](/molmil-images/mine/4jj0) | Crystal structure of MamP | Descriptor: | GLYCEROL, HEME C, MamP | Authors: | Siponen, M, Pignol, D, Arnoux, P. | Deposit date: | 2013-03-07 | Release date: | 2013-10-09 | Last modified: | 2013-11-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural insight into magnetochrome-mediated magnetite biomineralization. Nature, 502, 2013
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5SBC
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![BU of 5sbc by Molmil](/molmil-images/mine/5sbc) | Tubulin-maytansinoid-5a-complex | Descriptor: | (1S,2R,3S,5S,6S,16E,18E,20R)-11-chloro-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.1~10,14~.0~3,5~]hexacosa-10(26),11,13,16,18,21-hexaen-6-yl phenylacetate, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | Authors: | Marzullo, P, Boiarska, Z, Perez-Pena, H, Abel, A.-C, Alvarez-Bernad, B, Lucena-Agell, D, Vasile, F, Sironi, M, Steinmetz, M.O, Prota, A.E, Diaz, J.F, Pieraccini, S, Passarella, D. | Deposit date: | 2021-07-20 | Release date: | 2021-12-08 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | Maytansinol Derivatives: Side Reactions as a Chance for New Tubulin Binders. Chemistry, 28, 2022
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8BL6
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8B6N
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5HKF
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![BU of 5hkf by Molmil](/molmil-images/mine/5hkf) | Crystal structure of Mycobacterium tuberculosis H37Rv orotate phosphoribosyltransferase in complex with 5-phospho-alpha-D-ribosyl 1-diphosphate (PRPP) | Descriptor: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, Orotate phosphoribosyltransferase | Authors: | Donini, S, Ferraris, D.M, Bolognesi, G, Rizzi, M. | Deposit date: | 2016-01-14 | Release date: | 2017-01-25 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural investigations on orotate phosphoribosyltransferase from Mycobacterium tuberculosis, a key enzyme of the de novo pyrimidine biosynthesis. Sci Rep, 7, 2017
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8B6O
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