5SBC

Tubulin-maytansinoid-5a-complex

Summary for 5SBC

• Entry DOI: 10.2210/pdb5sbc/pdb
• Group deposition: T2R-TTL-maytansinoid structures (G_1002215)
• Descriptor: Tubulin alpha-1B chain, GLYCEROL, IMIDAZOLE, ... (14 entities in total)
• Functional Keywords: cell cycle, tubulin fold, cytoskeleton, microtubule
• Biological source: Rattus norvegicus (Rat); More
• Total number of polymer chains: 6
• Total formula weight: 265372.72

Authors

Marzullo, P.,Boiarska, Z.,Perez-Pena, H.,Abel, A.-C.,Alvarez-Bernad, B.,Lucena-Agell, D.,Vasile, F.,Sironi, M.,Steinmetz, M.O.,Prota, A.E.,Diaz, J.F.,Pieraccini, S.,Passarella, D. (deposition date: 2021-07-20, release date: 2021-12-08, Last modification date: 2022-03-09)

• Primary citation: Marzullo, P.,Boiarska, Z.,Perez-Pena, H.,Abel, A.C.,Alvarez-Bernad, B.,Lucena-Agell, D.,Vasile, F.,Sironi, M.,Altmann, K.H.,Prota, A.E.,Diaz, J.F.,Pieraccini, S.,Passarella, D.; Maytansinol Derivatives: Side Reactions as a Chance for New Tubulin Binders.; Chemistry, 28:e202103520-e202103520, 2022; PubMed: 34788896; DOI: 10.1002/chem.202103520

Experimental method

X-RAY DIFFRACTION (2.32 Å)