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PDB: 51630 results

2IND
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BU of 2ind by Molmil
Mn(II) Reconstituted Toluene/o-xylene Monooxygenase Hydroxylase X-ray Crystal Structure
Descriptor: HEXAETHYLENE GLYCOL, MANGANESE (II) ION, Toluene, ...
Authors:McCormick, M.S, Sazinsky, M.H, Condon, K.L, Lippard, S.J.
Deposit date:2006-10-06
Release date:2006-12-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:X-ray crystal structures of manganese(II)-reconstituted and native toluene/o-xylene monooxygenase hydroxylase reveal rotamer shifts in conserved residues and an enhanced view of the protein interior.
J.Am.Chem.Soc., 128, 2006
2FWN
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BU of 2fwn by Molmil
Phosphorylation of an active site serine in a ThDP-dependent enzyme by phosphonate inactivation
Descriptor: Benzoylformate decarboxylase, CALCIUM ION, MAGNESIUM ION, ...
Authors:Bera, A.K, Hasson, M.S.
Deposit date:2006-02-02
Release date:2006-12-19
Last modified:2021-08-04
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Mechanism-based inactivation of benzoylformate decarboxylase, a thiamin diphosphate-dependent enzyme
J.Am.Chem.Soc., 129, 2007
1F1W
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BU of 1f1w by Molmil
SRC SH2 THREF1TRP MUTANT COMPLEXED WITH THE PHOSPHOPEPTIDE S(PTR)VNVQN
Descriptor: PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC, S(PTR)VNVQN PHOSPHOPEPTIDE
Authors:Kimber, M.S, Nachman, J, Cunningham, A.M, Gish, G.D, Pawson, T, Pai, E.F.
Deposit date:2000-05-20
Release date:2000-07-06
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for specificity switching of the Src SH2 domain.
Mol.Cell, 5, 2000
2G4X
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BU of 2g4x by Molmil
Anomalous substructure od ribonuclease A (P3221)
Descriptor: CHLORIDE ION, SULFATE ION, ribonuclease pancreatic
Authors:Mueller-Dieckmann, C, Weiss, M.S.
Deposit date:2006-02-22
Release date:2007-02-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:On the routine use of soft X-rays in macromolecular crystallography. Part IV. Efficient determination of anomalous substructures in biomacromolecules using longer X-ray wavelengths.
Acta Crystallogr.,Sect.D, 63, 2007
2G52
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BU of 2g52 by Molmil
Anomalous substructure of trypsin (P21)
Descriptor: SULFATE ION, Trypsin
Authors:Mueller-Dieckmann, C, Weiss, M.S.
Deposit date:2006-02-22
Release date:2007-02-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:On the routine use of soft X-rays in macromolecular crystallography. Part IV. Efficient determination of anomalous substructures in biomacromolecules using longer X-ray wavelengths.
Acta Crystallogr.,Sect.D, 63, 2007
5WZN
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BU of 5wzn by Molmil
Alpha-N-acetylgalactosaminidase NagBb from Bifidobacterium bifidum - GalNAc complex
Descriptor: 2-acetamido-2-deoxy-alpha-D-galactopyranose, Alpha-N-acetylgalactosaminidase, CALCIUM ION, ...
Authors:Sato, M, Arakawa, T, Ashida, H, Fushinobu, S.
Deposit date:2017-01-18
Release date:2017-06-07
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The first crystal structure of a family 129 glycoside hydrolase from a probiotic bacterium reveals critical residues and metal cofactors
J. Biol. Chem., 292, 2017
2GHY
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BU of 2ghy by Molmil
Novel Crystal Form of the ColE1 Rom Protein
Descriptor: Regulatory protein rop
Authors:Jang, S.B, Jeong, M.S, Carter, R.J, Holbrook, E.L, Comolli, L.R, Holbrook, S.R.
Deposit date:2006-03-28
Release date:2006-05-30
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Novel crystal form of the ColE1 Rom protein.
Acta Crystallogr.,Sect.D, 62, 2006
2G4M
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BU of 2g4m by Molmil
Insulin collected at 2.0 A wavelength
Descriptor: Insulin A chain, Insulin B chain
Authors:Mueller-Dieckmann, C, Weiss, M.S.
Deposit date:2006-02-22
Release date:2007-02-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:On the routine use of soft X-rays in macromolecular crystallography. Part IV. Efficient determination of anomalous substructures in biomacromolecules using longer X-ray wavelengths.
Acta Crystallogr.,Sect.D, 63, 2007
7JVN
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BU of 7jvn by Molmil
Non-receptor Protein Tyrosine Phosphatase SHP2 in Complex with Allosteric Inhibitor Compound 24
Descriptor: 6-(4-amino-4-methylpiperidin-1-yl)-3-[(2,3-dichlorophenyl)sulfanyl]pyrazin-2-amine, PHOSPHATE ION, Tyrosine-protein phosphatase non-receptor type 11
Authors:Fodor, M, Stams, T.
Deposit date:2020-08-21
Release date:2020-09-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.917 Å)
Cite:Identification of TNO155, an Allosteric SHP2 Inhibitor for the Treatment of Cancer.
J.Med.Chem., 63, 2020
2G5M
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BU of 2g5m by Molmil
Spinophilin PDZ domain
Descriptor: Neurabin-2
Authors:Kelker, M.S, Peti, W.
Deposit date:2006-02-23
Release date:2007-01-09
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structural basis for spinophilin-neurabin receptor interaction.
Biochemistry, 46, 2007
1DPW
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BU of 1dpw by Molmil
STRUCTURE OF HEN EGG-WHITE LYSOZYME IN COMPLEX WITH MPD
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ...
Authors:Weiss, M.S, Palm, G.J, Hilgenfeld, R.
Deposit date:1999-12-28
Release date:2000-01-03
Last modified:2011-11-23
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Crystallization, structure solution and refinement of hen egg-white lysozyme at pH 8.0 in the presence of MPD.
Acta Crystallogr.,Sect.D, 56, 2000
5WZP
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BU of 5wzp by Molmil
Alpha-N-acetylgalactosaminidase NagBb from Bifidobacterium bifidum - ligand free
Descriptor: Alpha-N-acetylgalactosaminidase, CALCIUM ION, ZINC ION
Authors:Sato, M, Arakawa, T, Ashida, H, Fushinobu, S.
Deposit date:2017-01-18
Release date:2017-06-07
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:The first crystal structure of a family 129 glycoside hydrolase from a probiotic bacterium reveals critical residues and metal cofactors
J. Biol. Chem., 292, 2017
2INC
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BU of 2inc by Molmil
Native Toluene/o-xylene Monooxygenase Hydroxylase X-ray Crystal Structure
Descriptor: FE (III) ION, HEXAETHYLENE GLYCOL, Toluene, ...
Authors:McCormick, M.S, Sazinsky, M.H, Condon, K.L, Lippard, S.J.
Deposit date:2006-10-06
Release date:2006-11-28
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:X-ray crystal structures of manganese(II)-reconstituted and native toluene/o-xylene monooxygenase hydroxylase reveal rotamer shifts in conserved residues and an enhanced view of the protein interior.
J.Am.Chem.Soc., 128, 2006
3NKX
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BU of 3nkx by Molmil
Impaired binding of 14-3-3 to Raf1 is linked to Noonan and LEOPARD syndrome
Descriptor: 14-3-3 protein zeta/delta, PROPANOIC ACID, Peptide of RAF proto-oncogene serine/threonine-protein kinase
Authors:Schumacher, B, Weyand, M, Ottmann, C.
Deposit date:2010-06-21
Release date:2010-09-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Impaired binding of 14-3-3 to C-RAF in Noonan syndrome suggests new approaches in diseases with increased Ras signaling
Mol.Cell.Biol., 30, 2010
5WRC
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BU of 5wrc by Molmil
Crystal structure of proteinase K from Engyodontium album
Descriptor: NITRATE ION, PRASEODYMIUM ION, Proteinase K
Authors:Sugahara, M, Nakane, T, Suzuki, M, Masuda, T, Inoue, S, Numata, K.
Deposit date:2016-12-01
Release date:2017-11-29
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Hydroxyethyl cellulose matrix applied to serial crystallography
Sci Rep, 7, 2017
2IIR
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BU of 2iir by Molmil
Acetate kinase from a hypothermophile Thermotoga maritima
Descriptor: Acetate kinase
Authors:Mukhopadhyay, S, Hasson, M.S, Sanders, D.A.
Deposit date:2006-09-28
Release date:2007-09-11
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Acetate kinase from a hypothermophile Thermotoga maritima
To be Published
2H2G
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BU of 2h2g by Molmil
The Structural Basis of Sirtuin substrate affinity
Descriptor: HISTONE H3 PEPTIDE, NAD-dependent deacetylase, ZINC ION
Authors:Cosgrove, M.S, Wolberger, C.
Deposit date:2006-05-18
Release date:2006-11-28
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:The structural basis of sirtuin substrate affinity
Biochemistry, 45, 2006
2H2I
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BU of 2h2i by Molmil
The Structural basis of Sirtuin Substrate Affinity
Descriptor: (2S,5R,8R,11S,14S,17S,21R)-5,8,11,14,17-PENTAMETHYL-4,7,10,13,16,19-HEXAOXADOCOSANE-2,21-DIOL, NAD-dependent deacetylase, ZINC ION
Authors:Cosgrove, M.S, Wolberger, C.
Deposit date:2006-05-18
Release date:2006-12-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The structural basis of sirtuin substrate affinity
Biochemistry, 45, 2006
3N9U
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BU of 3n9u by Molmil
Crystal Structure of the Complex between the 25 kDa Subunit and the 59 kDa Subunit (RRM domain) of Human Cleavage Factor Im
Descriptor: Cleavage and polyadenylation specificity factor subunit 5, Cleavage and polyadenylation specificity factor subunit 7, GLYCEROL
Authors:Tresaugues, L, Welin, M, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Karlberg, T, Kol, S, Kotenyova, T, Moche, M, Nielsen, T.N, Nyman, T, Persson, C, Schuler, H, Schutz, P, Siponen, M.I, Thorsell, A.G, van der Berg, S, Wahlberg, E, Weigelt, J, Wisniewska, M, Nordlund, P, Structural Genomics Consortium (SGC)
Deposit date:2010-05-31
Release date:2010-07-21
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Crystal Structure of the Complex between the 25 kDa Subunit and the 59 kDa Subunit (RRM domain) of Human Cleavage Factor Im
To be Published
2H2H
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BU of 2h2h by Molmil
The Structural basis of sirtuin substrate specificity
Descriptor: Histone H4, NAD-dependent deacetylase, ZINC ION
Authors:Cosgrove, M.S, Wolberger, C.
Deposit date:2006-05-18
Release date:2006-12-05
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The structural basis of sirtuin substrate affinity
Biochemistry, 45, 2006
1F6L
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BU of 1f6l by Molmil
VARIABLE LIGHT CHAIN DIMER OF ANTI-FERRITIN ANTIBODY
Descriptor: ANTI-FERRITIN IMMUNOGLOBULIN LIGHT CHAIN
Authors:Nymalm, Y, Kravchuk, Z, Salminen, T, Chumanevich, A.A, Dubnovitsky, A.P, Kankare, J, Pentikainen, O, Lehtonen, J, Arosio, P, Martsev, S, Johnson, M.S.
Deposit date:2000-06-22
Release date:2002-10-23
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Antiferritin VL homodimer binds human spleen ferritin with high specificity
J.STRUCT.BIOL., 138, 2002
1F2F
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BU of 1f2f by Molmil
SRC SH2 THREF1TRP MUTANT
Descriptor: PHOSPHATE ION, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC
Authors:Kimber, M.S, Nachman, J, Cunningham, A.M, Gish, G.D, Pawson, T, Pai, E.F.
Deposit date:2000-05-24
Release date:2000-07-06
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis for specificity switching of the Src SH2 domain.
Mol.Cell, 5, 2000
2INN
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BU of 2inn by Molmil
Structure of the Phenol Hydroxyalse-Regulatory Protein Complex
Descriptor: FE (III) ION, MOLYBDATE ION, Phenol hydroxylase component phL, ...
Authors:Sazinsky, M.H, Dunten, P.W, McCormick, M.S, Lippard, S.J.
Deposit date:2006-10-08
Release date:2007-01-16
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:X-ray Structure of a Hydroxylase-Regulatory Protein Complex from a Hydrocarbon-Oxidizing Multicomponent Monooxygenase, Pseudomonas sp. OX1 Phenol Hydroxylase.
Biochemistry, 45, 2006
2IDY
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BU of 2idy by Molmil
NMR Structure of the SARS-CoV non-structural protein nsp3a
Descriptor: NSP3
Authors:Serrano, P, Almeida, M.S, Johnson, M.A, Horst, R, Herrmann, T, Joseph, J, Saikatendu, K, Subramanian, V, Stevens, R.C, Kuhn, P, Wuthrich, K, Joint Center for Structural Genomics (JCSG)
Deposit date:2006-09-15
Release date:2006-12-05
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Nuclear magnetic resonance structure of the N-terminal domain of nonstructural protein 3 from the severe acute respiratory syndrome coronavirus.
J.Virol., 81, 2007
3O1G
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BU of 3o1g by Molmil
Cathepsin K covalently bound to a 2-cyano pyrimidine inhibitor with a benzyl P3 group.
Descriptor: Cathepsin K, N-benzyl-3-(2-cyano-6-propylpyrimidin-4-yl)-N-[2-(dimethylamino)ethyl]-5-(trifluoromethyl)benzamide, SULFATE ION
Authors:Fradera, X, van Zeeland, M, Uitdehaag, J.C.M.
Deposit date:2010-07-21
Release date:2010-10-06
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Optimisation of 2-cyano-pyrimidine inhibitors of cathepsin K: improving selectivity over hERG.
Bioorg.Med.Chem.Lett., 20, 2010

224201

数据于2024-08-28公开中

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