8EN0
| Structure of GII.17 norovirus in complex with Nanobody 7 | 分子名称: | Capsid protein VP1, Nanobody 7 | 著者 | Kher, G, Sabin, C, Koromyslova, A, Pancera, M, Hansman, G. | 登録日 | 2022-09-28 | 公開日 | 2023-03-15 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | 主引用文献 | Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies. J.Virol., 97, 2023
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2VC5
| Structural basis for natural lactonase and promiscuous phosphotriesterase activities | 分子名称: | 1,2-ETHANEDIOL, ARYLDIALKYLPHOSPHATASE, COBALT (II) ION, ... | 著者 | Elias, M, Dupuy, J, Merone, L, Mandrich, L, Moniot, S, Lecomte, C, Rossi, M, Masson, P, Manco, G, Chabriere, E. | 登録日 | 2007-09-18 | 公開日 | 2008-04-15 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural Basis for Natural Lactonase and Promiscuous Phosphotriesterase Activities. J.Mol.Biol., 379, 2008
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8I94
| Structure of flavone 4'-O-glucoside 7-O-glucosyltransferase from Nemophila menziesii, complex with luteolin | 分子名称: | 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one, Glycosyltransferase, SULFATE ION | 著者 | Murayama, K, Kato-Murayama, M, Shirouzu, M. | 登録日 | 2023-02-06 | 公開日 | 2024-02-14 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | 主引用文献 | Molecular basis of ligand recognition specificity of flavone glucosyltransferases in Nemophila menziesii. Arch.Biochem.Biophys., 753, 2024
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8IE4
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8EN1
| Structure of GII.4 norovirus in complex with Nanobody 30 | 分子名称: | GII.4 P domain, Nanobody 30 | 著者 | Kher, G, Sabin, C, Pancera, M, Koromyslova, A, Hansman, G. | 登録日 | 2022-09-28 | 公開日 | 2023-03-15 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies. J.Virol., 97, 2023
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6HYG
| Heteromeric tandem IgG4/IgG1 Fc | 分子名称: | IgHG1 and IgHG4 hybrid, ZINC ION | 著者 | Casaletto, J.B, Geddie, M.L, Abu-Yousif, A.O, Masson, K, Fulgham, A, Boudot, A, Maiwald, T, Kearns, J.D, Kohli, N, Su, S, Razlog, M, Raue, A, Kalra, A, Hakansson, M, Logan, D.T, Welin, M, Chattopadhyay, S, Harms, B.D, Nielsen, U.B, Schoeberl, B, Lugovskoy, A.A, MacBeath, G. | 登録日 | 2018-10-21 | 公開日 | 2019-03-13 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | MM-131, a bispecific anti-Met/EpCAM mAb, inhibits HGF-dependent and HGF-independent Met signaling through concurrent binding to EpCAM. Proc.Natl.Acad.Sci.USA, 116, 2019
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6BP6
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8EN6
| Structure of GII.4 norovirus in complex with Nanobody 76 | 分子名称: | 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, GII.4 P domain, ... | 著者 | Kher, G, Sabin, C, Pancera, M, Koromyslova, A, Hansman, G. | 登録日 | 2022-09-28 | 公開日 | 2023-03-15 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies. J.Virol., 97, 2023
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5JIJ
| Structure of Mycobacterium thermoresistibile trehalose-6-phosphate synthase (APO form). | 分子名称: | 1,2-ETHANEDIOL, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Alpha,alpha-trehalose-phosphate synthase | 著者 | Mendes, V, Verma, N, Blaszczyk, M, Blundell, T.L. | 登録日 | 2016-04-22 | 公開日 | 2017-05-10 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Mycobacterial OtsA Structures Unveil Substrate Preference Mechanism and Allosteric Regulation by 2-Oxoglutarate and 2-Phosphoglycerate. Mbio, 10, 2019
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6SG4
| Structure of CDK2/cyclin A M246Q, S247EN | 分子名称: | Cyclin-A2, Cyclin-dependent kinase 2 | 著者 | Salamina, M, Basle, A, Massa, B, Noble, M.E.M, Endicott, J.A. | 登録日 | 2019-08-02 | 公開日 | 2021-01-27 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | 主引用文献 | Discriminative SKP2 Interactions with CDK-Cyclin Complexes Support a Cyclin A-Specific Role in p27KIP1 Degradation. J.Mol.Biol., 433, 2021
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7QIM
| In situ structure of nebulin bound to actin filament in skeletal sarcomere | 分子名称: | ACTS protein, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Wang, Z, Grange, M, Pospich, S, Wagner, T, Kho, A.L, Gautel, M, Raunser, S. | 登録日 | 2021-12-15 | 公開日 | 2022-03-16 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Structures from intact myofibrils reveal mechanism of thin filament regulation through nebulin. Science, 375, 2022
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5V7W
| Crystal structure of human PARP14 bound to 2-{[(1-methylpiperidin-4-yl)methyl]amino}-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one inhibitor | 分子名称: | 2-{[(1-methylpiperidin-4-yl)methyl]amino}-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one, Poly [ADP-ribose] polymerase 14 | 著者 | saikatendu, k.s, Hirozane, M. | 登録日 | 2017-03-20 | 公開日 | 2017-05-10 | 最終更新日 | 2018-11-14 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Identification of PARP14 inhibitors using novel methods for detecting auto-ribosylation. Biochem. Biophys. Res. Commun., 486, 2017
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6HUR
| 2'-fucosyllactose and 3-fucosyllactose binding protein from Bifidobacterium longum infantis, bound with 2'-fucosyllactose | 分子名称: | 2-(2-METHOXYETHOXY)ETHANOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ABC transporter substrate-binding protein, ... | 著者 | Ejby, M, Abou Hachem, M, Lo Leggio, L, Katayama, T, Sakanaka, M. | 登録日 | 2018-10-09 | 公開日 | 2019-09-04 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.297 Å) | 主引用文献 | Evolutionary adaptation in fucosyllactose uptake systems supports bifidobacteria-infant symbiosis. Sci Adv, 5, 2019
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8EMY
| Structure of GII.4 norovirus in complex with Nanobody 82 | 分子名称: | 1,2-ETHANEDIOL, GII.4 P domain, Nanobody 82 | 著者 | Kher, G, Sabin, C, Pancera, M, Koromyslova, A, Hansman, G. | 登録日 | 2022-09-28 | 公開日 | 2023-03-15 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies. J.Virol., 97, 2023
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8EN2
| Structure of GII.10 norovirus in complex with Nanobody 34 | 分子名称: | 1,2-ETHANEDIOL, GII.10 P domain, Nanobody 34 | 著者 | Kher, G, Sabin, C, Koromyslova, A, Pancera, M, Hansman, G. | 登録日 | 2022-09-28 | 公開日 | 2023-03-15 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies. J.Virol., 97, 2023
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7C3D
| Crystal structure of AofleA from Arthrobotrys oligospora in complex with D-arabinose | 分子名称: | AofleA, GLYCEROL, alpha-D-arabinopyranose, ... | 著者 | Liu, M, Cheng, X, Wang, J, Zhang, M, Wang, M. | 登録日 | 2020-05-12 | 公開日 | 2020-07-29 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.596 Å) | 主引用文献 | Structural insights into the fungi-nematodes interaction mediated by fucose-specific lectin AofleA from Arthrobotrys oligospora. Int.J.Biol.Macromol., 164, 2020
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8EN3
| Structure of GII.17 norovirus in complex with Nanobody 45 | 分子名称: | 1,2-ETHANEDIOL, Capsid protein VP1, Nanobody 45 | 著者 | Kher, G, Sabin, C, Pancera, M, Koromyslova, A, Hansman, G. | 登録日 | 2022-09-28 | 公開日 | 2023-03-15 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies. J.Virol., 97, 2023
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5NRT
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5NHQ
| Nuclear Magnetic Resonance Structure of the Human Polyoma JC Virus Agnoprotein | 分子名称: | Agnoprotein | 著者 | Coric, P, Saribas, A.S, Abou-Gharbia, M, Childers, W, Condra, J, White, M.K, Safak, M, Bouaziz, S. | 登録日 | 2017-03-22 | 公開日 | 2017-04-26 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | Nuclear Magnetic Resonance Structure of the Human Polyoma JC Virus Agnoprotein. J. Cell. Biochem., 118, 2017
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8EXP
| Cryo-EM structure of S. aureus BlaR1 with C2 symmetry | 分子名称: | Beta-lactam sensor/signal transducer BlaR1, ZINC ION | 著者 | Worrall, L.J, Alexander, J.A.N, Vuckovic, M, Strynadka, N.C.J. | 登録日 | 2022-10-25 | 公開日 | 2023-01-11 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Structural basis of broad-spectrum beta-lactam resistance in Staphylococcus aureus. Nature, 613, 2023
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5NS5
| Cys-Gly dipeptidase GliJ in complex with Cu2+ and Zn2+ | 分子名称: | CHLORIDE ION, COPPER (II) ION, Dipeptidase gliJ, ... | 著者 | Groll, M, Huber, E.M. | 登録日 | 2017-04-25 | 公開日 | 2017-05-31 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Gliotoxin Biosynthesis: Structure, Mechanism, and Metal Promiscuity of Carboxypeptidase GliJ. ACS Chem. Biol., 12, 2017
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5J6N
| Crystal Structure of Hsp90-alpha N-domain L107A mutant in complex with 5-[4-(2-Fluoro-phenyl)-5-oxo-4,5-dihydro-1H-[1,2,4]triazol-3-yl]-2,4-dihydroxy-N-methyl-N-propyl-benzenesulfonamide | 分子名称: | 5-[4-(2-fluorophenyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl]-2,4-dihydroxy-N-methyl-N-propylbenzene-1-sulfonamide, Heat shock protein HSP 90-alpha | 著者 | Amaral, M, Matias, P. | 登録日 | 2016-04-05 | 公開日 | 2017-12-06 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Protein conformational flexibility modulates kinetics and thermodynamics of drug binding. Nat Commun, 8, 2017
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6RLC
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5J82
| Crystal Structure of Hsp90-alpha N-domain in complex 5-[4-(2-Fluoro-phenyl)-5-oxo-4,5-dihydro-1H-[1,2,4]triazol-3-yl]-2,4-dihydroxy-N-isopropyl-N-methyl-benzenesulfonamide | 分子名称: | 5-[4-(2-fluorophenyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl]-2,4-dihydroxy-N-methyl-N-(propan-2-yl)benzene-1-sulfonamide, Heat shock protein HSP 90-alpha | 著者 | Amaral, M, Matias, P. | 登録日 | 2016-04-07 | 公開日 | 2017-12-06 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | Protein conformational flexibility modulates kinetics and thermodynamics of drug binding. Nat Commun, 8, 2017
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5JM6
| Structure of Chaetomium thermophilum mApe1 | 分子名称: | Aminopeptidase-like protein, ZINC ION | 著者 | Bertipaglia, C, Jakobi, A.J, Wilmanns, M, Sachse, C. | 登録日 | 2016-04-28 | 公開日 | 2016-06-15 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.758 Å) | 主引用文献 | Higher-order assemblies of oligomeric cargo receptor complexes form the membrane scaffold of the Cvt vesicle. Embo Rep., 17, 2016
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