6Q4M
 
 | | Crystal structure of the O-GlcNAc transferase Asn648Tyr mutation | | 分子名称: | (2S,3R,4R,5S,6R)-3-(acetylamino)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-thiopyran-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate, PHOSPHATE ION, UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | | 著者 | Gundogdu, M, van Aalten, D.M.F. | | 登録日 | 2018-12-06 | | 公開日 | 2019-12-25 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of the O-GlcNAc transferase Asn648Tyr mutation
To Be Published
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6Q56
 | | Crystal structure of the B. subtilis M1A22 tRNA methyltransferase TrmK | | 分子名称: | NICKEL (II) ION, tRNA (adenine(22)-N(1))-methyltransferase | | 著者 | Degut, C, Roovers, M, Barraud, P, Brachet, F, Feller, A, Larue, V, Al Refaii, A, Caillet, J, Droogmans, L, Tisne, C. | | 登録日 | 2018-12-07 | | 公開日 | 2019-03-27 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural characterization of B. subtilis m1A22 tRNA methyltransferase TrmK: insights into tRNA recognition.
Nucleic Acids Res., 47, 2019
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5ZRS
 | | Crystal structure of PET-degrading cutinase Cut190 S176A/S226P/R228S mutant in monoethyl adipate bound state | | 分子名称: | 6-ethoxy-6-oxohexanoic acid, Alpha/beta hydrolase family protein, CALCIUM ION, ... | | 著者 | Numoto, N, Kamiya, N, Bekker, G.J, Yamagami, Y, Inaba, S, Ishii, K, Uchiyama, S, Kawai, F, Ito, N, Oda, M. | | 登録日 | 2018-04-25 | | 公開日 | 2018-09-12 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structural Dynamics of the PET-Degrading Cutinase-like Enzyme from Saccharomonospora viridis AHK190 in Substrate-Bound States Elucidates the Ca2+-Driven Catalytic Cycle.
Biochemistry, 57, 2018
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6Q6U
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6Q6Z
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6Q4R
 | | High-resolution crystal structure of ERAP1 with bound phosphinic transition-state analogue inhibitor | | 分子名称: | 1,2-ETHANEDIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Giastas, P, Neu, M, Rowland, P, Stratikos, E. | | 登録日 | 2018-12-06 | | 公開日 | 2019-04-10 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | High-Resolution Crystal Structure of Endoplasmic Reticulum Aminopeptidase 1 with Bound Phosphinic Transition-State Analogue Inhibitor.
Acs Med.Chem.Lett., 10, 2019
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6Q82
 | | Crystal structure of the biportin Pdr6 in complex with RanGTP | | 分子名称: | GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, Importin beta-like protein KAP122, ... | | 著者 | Aksu, M, Vera-Rodriguez, A, Trakhanov, S, Gorlich, D. | | 登録日 | 2018-12-14 | | 公開日 | 2019-05-01 | | 最終更新日 | 2019-06-12 | | 実験手法 | X-RAY DIFFRACTION (2.994 Å) | | 主引用文献 | Structural basis for the nuclear import and export functions of the biportin Pdr6/Kap122.
J.Cell Biol., 218, 2019
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8QLH
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8QLK
 | | Crystal structure of the pneumococcal Substrate-binding protein AliB in complex with Peptide 2 | | 分子名称: | ALA-ILE-GLN-SER-GLU-LYS-ALA-ARG-LYS-HIS-ASN, Oligopeptide-binding protein AliB | | 著者 | Alcorlo, M, Abdullah, M.R, Hammerschmidt, S, Hermoso, J. | | 登録日 | 2023-09-20 | | 公開日 | 2024-05-22 | | 最終更新日 | 2024-07-03 | | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | | 主引用文献 | Molecular and structural basis of oligopeptide recognition by the Ami transporter system in pneumococci.
Plos Pathog., 20, 2024
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5ZT6
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8QQ5
 | | Structure of WT SpNox DH domain: a bacterial NADPH oxidase. | | 分子名称: | CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, Oxidoreductase | | 著者 | Thepaut, M, Petit-Hartlein, I, Vermot, A, Humm, A.S, Dupeux, F, Marquez, J.A, Smith, S, Fieschi, F. | | 登録日 | 2023-10-03 | | 公開日 | 2024-05-08 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | X-ray structure and enzymatic study of a bacterial NADPH oxidase highlight the activation mechanism of eukaryotic NOX.
Elife, 13, 2024
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8QLJ
 | | Crystal structure of the pneumococcal Substrate-binding protein AliB in complex with an unknown peptide | | 分子名称: | ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA, Oligopeptide-binding protein AliB | | 著者 | Alcorlo, M, Abdullah, M.R, Hammerschmidt, S, Hermoso, J. | | 登録日 | 2023-09-20 | | 公開日 | 2024-05-22 | | 最終更新日 | 2024-07-03 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Molecular and structural basis of oligopeptide recognition by the Ami transporter system in pneumococci.
Plos Pathog., 20, 2024
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6Q6C
 | | Pore-modulating toxins exploit inherent slow inactivation to block K+ channels | | 分子名称: | 1,2-ETHANEDIOL, Kunitz-type conkunitzin-S1, NITRATE ION, ... | | 著者 | Karbat, I, Gueta, H, Fine, S, Szanto, T, Hamer-Rogotner, S, Dym, O, Frolow, F, Gordon, D, Panyi, G, Gurevitz, M, Reuveny, E. | | 登録日 | 2018-12-10 | | 公開日 | 2019-08-21 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Pore-modulating toxins exploit inherent slow inactivation to block K+channels.
Proc.Natl.Acad.Sci.USA, 116, 2019
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8QLC
 | | Crystal structure of the pneumococcal Substrate-binding protein AliD in open conformation | | 分子名称: | AliD, MAGNESIUM ION | | 著者 | Alcorlo, M, Abdullah, M.R, Hammerschmidt, S, Hermoso, J. | | 登録日 | 2023-09-19 | | 公開日 | 2024-05-22 | | 最終更新日 | 2024-07-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Molecular and structural basis of oligopeptide recognition by the Ami transporter system in pneumococci.
Plos Pathog., 20, 2024
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8QPJ
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6QGA
 | | Crystal structure of Ideonella sakaiensis MHETase bound to the non-hydrolyzable ligand MHETA | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 4-(2-hydroxyethylcarbamoyl)benzoic acid, CALCIUM ION, ... | | 著者 | Palm, G.J, Reisky, L, Boettcher, D, Mueller, H, Michels, E.A.P, Walczak, C, Berndt, L, Weiss, M.S, Bornscheuer, U.T, Weber, G. | | 登録日 | 2019-01-10 | | 公開日 | 2019-04-03 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure of the plastic-degrading Ideonella sakaiensis MHETase bound to a substrate.
Nat Commun, 10, 2019
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8QLM
 | | Crystal structure of the pneumococcal Substrate-binding protein AliB in complex with Peptide 3 | | 分子名称: | Oligopeptide-binding protein AliB, PRO-ILE-VAL-GLY-GLY-HIS-GLU-GLY-ALA-GLY-VAL | | 著者 | Alcorlo, M, Abdullah, M.R, Hammerschmidt, S, Hermoso, J. | | 登録日 | 2023-09-20 | | 公開日 | 2024-05-22 | | 最終更新日 | 2024-07-03 | | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | | 主引用文献 | Molecular and structural basis of oligopeptide recognition by the Ami transporter system in pneumococci.
Plos Pathog., 20, 2024
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8QPL
 | | F420-Dependent Methylene-Tetrahydromethanopterin Reductase with F420 from Methanocaldococcus jannaschii | | 分子名称: | 5,10-methylenetetrahydromethanopterin reductase, COENZYME F420 | | 著者 | Gehl, M, Demmer, U, Ermler, U, Shima, S. | | 登録日 | 2023-10-02 | | 公開日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Mutational and structural studies of ( beta alpha ) 8 -barrel fold methylene-tetrahydropterin reductases utilizing a common catalytic mechanism.
Protein Sci., 33, 2024
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8QQ8
 | | Crystal Structure of F420-dependent Methylene-Tetrahydromethanopterin Reductase Mutant E6Q from Methanocaldococcus Jannaschii | | 分子名称: | 5,10-methylenetetrahydromethanopterin reductase | | 著者 | Gehl, M, Demmer, U, Ermler, U, Shima, S. | | 登録日 | 2023-10-04 | | 公開日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Mutational and structural studies of ( beta alpha ) 8 -barrel fold methylene-tetrahydropterin reductases utilizing a common catalytic mechanism.
Protein Sci., 33, 2024
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1AC9
 | | SOLUTION STRUCTURE OF A DNA DECAMER CONTAINING THE ANTIVIRAL DRUG GANCICLOVIR: COMBINED USE OF NMR, RESTRAINED MOLECULAR DYNAMICS, AND FULL RELAXATION REFINEMENT, 6 STRUCTURES | | 分子名称: | DNA | | 著者 | Foti, M, Marshalko, S, Schurter, E, Kumar, S, Beardsley, G.P, Schweitzer, B.I. | | 登録日 | 1997-02-17 | | 公開日 | 1997-07-07 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of a DNA decamer containing the antiviral drug ganciclovir: combined use of NMR, restrained molecular dynamics, and full relaxation matrix refinement.
Biochemistry, 36, 1997
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6QD4
 | | MloK1 model from single particle analysis of 2D crystals, class 8 (intermediate conformation) | | 分子名称: | Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION | | 著者 | Righetto, R, Biyani, N, Kowal, J, Chami, M, Stahlberg, H. | | 登録日 | 2018-12-31 | | 公開日 | 2019-04-24 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (5.6 Å) | | 主引用文献 | Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM.
Nat Commun, 10, 2019
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1A4P
 | | P11 (S100A10), LIGAND OF ANNEXIN II | | 分子名称: | S100A10 | | 著者 | Rety, S, Sopkova, J, Renouard, M, Osterloh, D, Gerke, V, Russo-Marie, F, Lewit-Bentley, A. | | 登録日 | 1998-01-30 | | 公開日 | 1998-05-27 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | The crystal structure of a complex of p11 with the annexin II N-terminal peptide.
Nat.Struct.Biol., 6, 1999
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6QBP
 | | structure of the core domaine of Knr4, an intrinsically disordered protein from Saccharomyces cerevisiae - mutant S203D | | 分子名称: | Cell wall assembly regulator SMI1 | | 著者 | Ramos, N, Batista, M, Francois, J.M, Mourey, L, Maveyraud, L, Zerbib, D. | | 登録日 | 2018-12-21 | | 公開日 | 2020-01-29 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | structure of the core domaine of Knr4, an intrinsically disordered protein from Saccharomyces cerevisiae - mutant S203D
To Be Published
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6QEN
 | | Crystal structure of Porcine Pancreatic Elastase (PPE) in complex with the 3-Oxo-beta-Sultam inhibitor LMC240 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1-[[1-[(4-bromophenyl)methyl]-1,2,3-triazol-4-yl]methylamino]-2-methyl-1-oxidanylidene-propane-2-sulfonic acid, Chymotrypsin-like elastase family member 1, ... | | 著者 | Brito, J.A, Almeida, V.T, Carvalho, L.M, Moreira, R, Archer, M. | | 登録日 | 2019-01-08 | | 公開日 | 2020-03-25 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.195 Å) | | 主引用文献 | 3-Oxo-beta-sultam as a Sulfonylating Chemotype for Inhibition of Serine Hydrolases and Activity-Based Protein Profiling.
Acs Chem.Biol., 15, 2020
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6AAO
 | | Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with TCO*Lys | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... | | 著者 | Yanagisawa, T, Kuratani, M, Yokoyama, S. | | 登録日 | 2018-07-18 | | 公開日 | 2019-04-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.403 Å) | | 主引用文献 | Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase.
Cell Chem Biol, 26, 2019
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