8QQ5

Structure of WT SpNox DH domain: a bacterial NADPH oxidase.

Summary for 8QQ5

• Entry DOI: 10.2210/pdb8qq5/pdb
• Descriptor: Oxidoreductase, FLAVIN-ADENINE DINUCLEOTIDE, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: nadph oxidase, reactive oxygen species production, membrane protein, dehydrogenase domain, streptococcus pneumoniae., electron transport
• Biological source: Streptococcus pneumoniae
• Total number of polymer chains: 3
• Total formula weight: 78502.36

Authors

Thepaut, M.,Petit-Hartlein, I.,Vermot, A.,Humm, A.S.,Dupeux, F.,Marquez, J.A.,Smith, S.,Fieschi, F. (deposition date: 2023-10-03, release date: 2024-05-08, Last modification date: 2024-05-15)

• Primary citation: Petit-Hartlein, I.,Vermot, A.,Thepaut, M.,Humm, A.S.,Dupeux, F.,Dupuy, J.,Chaptal, V.,Marquez, J.A.,Smith, S.M.E.,Fieschi, F.; X-ray structure and enzymatic study of a bacterial NADPH oxidase highlight the activation mechanism of eukaryotic NOX.; Elife, 13:-, 2024; PubMed: 38640072; DOI: 10.7554/eLife.93759

Experimental method

X-RAY DIFFRACTION (2.5 Å)