6Q4M

Crystal structure of the O-GlcNAc transferase Asn648Tyr mutation

Summary for 6Q4M

• Entry DOI: 10.2210/pdb6q4m/pdb
• Descriptor: UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, (2S,3R,4R,5S,6R)-3-(acetylamino)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-thiopyran-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate, PHOSPHATE ION, ... (4 entities in total)
• Functional Keywords: glycosyltransferase, acceptor peptide, mutation, disease, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 81836.94

Authors

Gundogdu, M.,van Aalten, D.M.F. (deposition date: 2018-12-06, release date: 2019-12-25)

• Primary citation: Gundogdu, M.,van Aalten, D.M.F.; Crystal structure of the O-GlcNAc transferase Asn648Tyr mutation; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.2 Å)