6Q4R
High-resolution crystal structure of ERAP1 with bound phosphinic transition-state analogue inhibitor
Summary for 6Q4R
| Entry DOI | 10.2210/pdb6q4r/pdb |
| Descriptor | Endoplasmic reticulum aminopeptidase 1,Endoplasmic reticulum aminopeptidase 1, HEXAETHYLENE GLYCOL, TETRAETHYLENE GLYCOL, ... (13 entities in total) |
| Functional Keywords | endoplasmic reticulum aminopeptidase 1, erap1, antigen presentation, hydrolase |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 1 |
| Total formula weight | 108762.05 |
| Authors | Giastas, P.,Neu, M.,Rowland, P.,Stratikos, E. (deposition date: 2018-12-06, release date: 2019-04-10, Last modification date: 2024-01-24) |
| Primary citation | Giastas, P.,Neu, M.,Rowland, P.,Stratikos, E. High-Resolution Crystal Structure of Endoplasmic Reticulum Aminopeptidase 1 with Bound Phosphinic Transition-State Analogue Inhibitor. Acs Med.Chem.Lett., 10:708-713, 2019 Cited by PubMed: 31097987DOI: 10.1021/acsmedchemlett.9b00002 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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