8SGW
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![BU of 8sgw by Molmil](/molmil-images/mine/8sgw) | Pendrin in complex with chloride | 分子名称: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, CHLORIDE ION, CHOLESTEROL, ... | 著者 | Wang, L, Hoang, A, Zhou, M. | 登録日 | 2023-04-13 | 公開日 | 2024-02-07 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Mechanism of anion exchange and small-molecule inhibition of pendrin. Nat Commun, 15, 2024
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8SHC
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![BU of 8shc by Molmil](/molmil-images/mine/8shc) | Pendrin in complex with Niflumic acid | 分子名称: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 2-{[3-(TRIFLUOROMETHYL)PHENYL]AMINO}NICOTINIC ACID, CHLORIDE ION, ... | 著者 | Wang, L, Hoang, A, Zhou, M. | 登録日 | 2023-04-13 | 公開日 | 2024-02-07 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Mechanism of anion exchange and small-molecule inhibition of pendrin. Nat Commun, 15, 2024
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8SIE
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![BU of 8sie by Molmil](/molmil-images/mine/8sie) | Pendrin in complex with bicarbonate | 分子名称: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, BICARBONATE ION, CHOLESTEROL, ... | 著者 | Wang, L, Hoang, A, Zhou, M. | 登録日 | 2023-04-16 | 公開日 | 2024-02-07 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Mechanism of anion exchange and small-molecule inhibition of pendrin. Nat Commun, 15, 2024
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5HIL
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![BU of 5hil by Molmil](/molmil-images/mine/5hil) | Crystal structure of glycine sarcosine N-methyltransferase from Methanohalophilus portucalensis in complex with S-adenosylhomocysteine and sarcosine | 分子名称: | 1,2-ETHANEDIOL, Glycine sarcosine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, ... | 著者 | Lee, Y.R, Lin, T.S, Lai, S.J, Liu, M.S, Lai, M.C, Chan, N.L. | 登録日 | 2016-01-12 | 公開日 | 2016-11-23 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.471 Å) | 主引用文献 | Structural Analysis of Glycine Sarcosine N-methyltransferase from Methanohalophilus portucalensis Reveals Mechanistic Insights into the Regulation of Methyltransferase Activity Sci Rep, 6, 2016
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6QJ2
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6Q7L
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![BU of 6q7l by Molmil](/molmil-images/mine/6q7l) | Spiral structure of E. coli RavA in the RavA-LdcI cage-like complex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATPase RavA, Inducible lysine decarboxylase, ... | 著者 | Arragain, B, Felix, J, Malet, H, Gutsche, I, Jessop, M. | 登録日 | 2018-12-13 | 公開日 | 2020-02-12 | 最終更新日 | 2020-02-19 | 実験手法 | ELECTRON MICROSCOPY (7.6 Å) | 主引用文献 | Structural insights into ATP hydrolysis by the MoxR ATPase RavA and the LdcI-RavA cage-like complex. Commun Biol, 3, 2020
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5HD7
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![BU of 5hd7 by Molmil](/molmil-images/mine/5hd7) | Dissecting Therapeutic Resistance to ERK Inhibition Rat Mutant SCH772984 in complex with (3R)-1-(2-oxo-2-{4-[4-(pyrimidin-2-yl)phenyl]piperazin-1-yl}ethyl)-N-[3-(pyridin-4-yl)-2H-indazol-5-yl]pyrrolidine-3-carboxamide | 分子名称: | (3R)-1-(2-oxo-2-{4-[4-(pyrimidin-2-yl)phenyl]piperazin-1-yl}ethyl)-N-[3-(pyridin-4-yl)-2H-indazol-5-yl]pyrrolidine-3-carboxamide, Mitogen-activated protein kinase 1, SULFATE ION | 著者 | Jha, S, Morris, E.J, Hruza, A, Mansueto, M.S, Schroeder, G, Arbanas, J, McMasters, D, Restaino, C.R, Dayananth, R, Black, S, Elsen, N.L, Mannarino, A, Cooper, A, Fawell, S, Zawel, L, Jayaraman, L, Samatar, A.A. | 登録日 | 2016-01-04 | 公開日 | 2016-02-24 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Dissecting Therapeutic Resistance to ERK Inhibition. Mol.Cancer Ther., 15, 2016
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5YO8
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![BU of 5yo8 by Molmil](/molmil-images/mine/5yo8) | |
8RXA
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![BU of 8rxa by Molmil](/molmil-images/mine/8rxa) | |
8SDG
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![BU of 8sdg by Molmil](/molmil-images/mine/8sdg) | |
8SDF
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![BU of 8sdf by Molmil](/molmil-images/mine/8sdf) | |
8RWU
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5YSF
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![BU of 5ysf by Molmil](/molmil-images/mine/5ysf) | Crystal structure of beta-1,2-glucooligosaccharide binding protein in complex with sophoropentaose | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Lin1841 protein, MAGNESIUM ION, ... | 著者 | Abe, K, Nakajima, M, Taguchi, H, Arakawa, T, Fushinobu, S. | 登録日 | 2017-11-14 | 公開日 | 2018-05-02 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural and thermodynamic insights into beta-1,2-glucooligosaccharide capture by a solute-binding protein inListeria innocua. J. Biol. Chem., 293, 2018
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4OQF
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![BU of 4oqf by Molmil](/molmil-images/mine/4oqf) | Mycobacterium tuberculosis RecA glycerol bound low temperature structure IIB-SR | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Protein RecA | 著者 | Chandran, A.V, Prabu, J.R, Patil, N.K, Muniyappa, K, Vijayan, M. | 登録日 | 2014-02-09 | 公開日 | 2015-03-18 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural studies on Mycobacterium tuberculosis RecA: Molecular plasticity and interspecies variability J.Biosci., 40, 2015
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8RXO
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5Y8C
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![BU of 5y8c by Molmil](/molmil-images/mine/5y8c) | Crystal Structure Analysis of the BRD4 | 分子名称: | 1,2-ETHANEDIOL, 5-chloranyl-2-methoxy-N-(6-methoxy-3-methyl-1,2-benzoxazol-5-yl)benzenesulfonamide, Bromodomain-containing protein 4, ... | 著者 | Xu, Y, Zhang, Y, Song, M, Wang, C. | 登録日 | 2017-08-21 | 公開日 | 2018-06-13 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | 主引用文献 | Structure-Based Discovery and Optimization of Benzo[ d]isoxazole Derivatives as Potent and Selective BET Inhibitors for Potential Treatment of Castration-Resistant Prostate Cancer (CRPC) J. Med. Chem., 61, 2018
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8ROX
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![BU of 8rox by Molmil](/molmil-images/mine/8rox) | Structure of the human DDB1-DDA1-DCAF15 E3 ubiquitin ligase bound to compound furan 12 | 分子名称: | 5-[[3,4-bis(chloranyl)-1~{H}-indol-7-yl]sulfamoyl]-~{N},~{N},3-trimethyl-furan-2-carboxamide;ethane, DDB1- and CUL4-associated factor 15, DET1- and DDB1-associated protein 1, ... | 著者 | Shilliday, F, Lucas, S.C.C, Richter, M, Michaelides, I.N, Fusani, L. | 登録日 | 2024-01-12 | 公開日 | 2024-04-03 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Optimization of Potent Ligands for the E3 Ligase DCAF15 and Evaluation of Their Use in Heterobifunctional Degraders. J.Med.Chem., 67, 2024
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6YJ0
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5FYE
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![BU of 5fye by Molmil](/molmil-images/mine/5fye) | Pseudomonas aeruginosa RmlA in complex with allosteric inhibitor | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE, ... | 著者 | Alphey, M.S, Tran, F, Westwood, N.J, Naismith, J.H. | 登録日 | 2016-03-07 | 公開日 | 2017-03-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Allosteric Competitive Inhibitors of the Glucose-1-Phosphate Thymidylyltransferase (Rmla) from Pseudomonas Aeruginosa. To be Published
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8ROY
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![BU of 8roy by Molmil](/molmil-images/mine/8roy) | Structure of the human DDB1-DDA1-DCAF15 E3 ubiquitin ligase bound to compound furan 24 | 分子名称: | 1-[5-[[3,4-bis(chloranyl)-1~{H}-indol-7-yl]sulfamoyl]-3-methyl-furan-2-yl]carbonyl-~{N}-methyl-piperidine-4-carboxamide, DDB1- and CUL4-associated factor 15, DET1- and DDB1-associated protein 1, ... | 著者 | Shilliday, F, Lucas, S.C.C, Richter, M, Michaelides, I.N, Fusani, L. | 登録日 | 2024-01-12 | 公開日 | 2024-04-03 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Optimization of Potent Ligands for the E3 Ligase DCAF15 and Evaluation of Their Use in Heterobifunctional Degraders. J.Med.Chem., 67, 2024
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5YTD
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![BU of 5ytd by Molmil](/molmil-images/mine/5ytd) | large fragment of DNA Polymerase I from Thermus aquaticus in a closed ternary complex with the natural base pair 5fC:dGTP | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*AP*AP*(5FC)P*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), ... | 著者 | Zeng, H, Mondal, M, Song, R.Y, Zhang, J, Xia, B, Gao, Y.Q, Yi, C.Q. | 登録日 | 2017-11-17 | 公開日 | 2018-11-21 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Unnatural Cytosine Bases Recognized as Thymines by DNA Polymerases by the Formation of the Watson-Crick Geometry. Angew. Chem. Int. Ed. Engl., 58, 2019
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6YUG
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![BU of 6yug by Molmil](/molmil-images/mine/6yug) | Crystal structure of C. parvum GNA1 in complex with acetyl-CoA and glucose 6P. | 分子名称: | 6-O-phosphono-alpha-D-glucopyranose, ACETYL COENZYME *A, Diamine acetyltransferase | 著者 | Chi, J, Cova, M, de las Rivas, M, Medina, A, Borges, R, Leivar, P, Planas, A, Uson, I, Hurtado-Guerrero, R, Izquierdo, L. | 登録日 | 2020-04-27 | 公開日 | 2020-09-30 | 最終更新日 | 2020-11-04 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Plasmodium falciparum Apicomplexan-Specific Glucosamine-6-Phosphate N -Acetyltransferase Is Key for Amino Sugar Metabolism and Asexual Blood Stage Development. Mbio, 11, 2020
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5YEI
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![BU of 5yei by Molmil](/molmil-images/mine/5yei) | Mechanistic insight into the regulation of Pseudomonas aeruginosa aspartate kinase | 分子名称: | Aspartokinase, GLYCEROL, LYSINE, ... | 著者 | Li, C, Yang, M, Liu, L, Peng, C, Li, T, He, L, Song, Y, Zhu, Y, Bao, R. | 登録日 | 2017-09-17 | 公開日 | 2018-08-29 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | 主引用文献 | Mechanistic insights into the allosteric regulation of Pseudomonas aeruginosa aspartate kinase. Biochem.J., 475, 2018
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5YC5
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![BU of 5yc5 by Molmil](/molmil-images/mine/5yc5) | Crystal structure of human IgG-Fc in complex with aglycan and optimized Fc gamma receptor IIIa | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Immunoglobulin gamma-1 heavy chain, ... | 著者 | Caaveiro, J.M.M, Tamura, H, Tsumoto, K, Kiyoshi, M. | 登録日 | 2017-09-06 | 公開日 | 2018-03-21 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | Assessing the Heterogeneity of the Fc-Glycan of a Therapeutic Antibody Using an engineered Fc gamma Receptor IIIa-Immobilized Column. Sci Rep, 8, 2018
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6YSO
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![BU of 6yso by Molmil](/molmil-images/mine/6yso) | Crystal structure of the (SR) Ca2+-ATPase solved by vanadium SAD phasing | 分子名称: | CHLORIDE ION, MAGNESIUM ION, OCTANOIC ACID [3S-[3ALPHA, ... | 著者 | El Omari, K, Mohamad, N, Bountra, K, Duman, R, Romano, M, Schlegel, K, Kwong, H, Mykhaylyk, V, Olesen, C.E, Moller, J.V, Bublitz, M, Beis, K, Wagner, A. | 登録日 | 2020-04-22 | 公開日 | 2020-11-04 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (3.13 Å) | 主引用文献 | Experimental phasing with vanadium and application to nucleotide-binding membrane proteins. Iucrj, 7, 2020
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