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PDB: 51964 件

4Q1I
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Structure and mechanism of a dehydratase/decarboxylase enzyme couple involved in polyketide beta-branching
分子名称: GLYCEROL, Polyketide biosynthesis enoyl-CoA isomerase PksI
著者Nair, A.V, Race, P.R, Till, M.
登録日2014-04-03
公開日2015-05-06
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure and mechanism of a dehydratase/decarboxylase enzyme couple involved in polyketide beta-methyl branch incorporation.
Sci Rep, 10, 2020
4M9F
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Dengue virus NS2B-NS3 protease A125C variant at pH 8.5
分子名称: NS2B-NS3 protease
著者Yildiz, M, Ghosh, S, Bell, J.A, Sherman, W, Hardy, J.A.
登録日2013-08-14
公開日2013-11-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Allosteric Inhibition of the NS2B-NS3 Protease from Dengue Virus.
Acs Chem.Biol., 8, 2013
1JB2
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CRYSTAL STRUCTURE OF NTF2 M84E MUTANT
分子名称: NUCLEAR TRANSPORT FACTOR 2
著者Chaillan-Huntington, C, Butler, P.J, Huntington, J.A, Akin, D, Feldherr, C, Stewart, M.
登録日2001-06-01
公開日2002-03-13
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献NTF2 monomer-dimer equilibrium.
J.Mol.Biol., 314, 2001
1JCC
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Crystal Structure of a Novel Alanine-Zipper Trimer at 1.7 A Resolution, V13A,L16A,V20A,L23A,V27A,M30A,V34A mutations
分子名称: MAJOR OUTER MEMBRANE LIPOPROTEIN, ZINC ION
著者Liu, J, Dai, J, Lu, M.
登録日2001-06-08
公開日2003-06-17
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Zinc-Mediated Helix Capping in A Triple-Helical Protein
Biochemistry, 42, 2003
4Q4H
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TM287/288 in its apo state
分子名称: ABC transporter, Uncharacterized ABC transporter ATP-binding protein TM_0288
著者Hohl, M, Gruetter, M.G, Seeger, M.A.
登録日2014-04-14
公開日2014-07-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.527 Å)
主引用文献Structural basis for allosteric cross-talk between the asymmetric nucleotide binding sites of a heterodimeric ABC exporter.
Proc.Natl.Acad.Sci.USA, 111, 2014
1JE8
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Two-Component response regulator NarL/DNA Complex: DNA Bending Found in a High Affinity Site
分子名称: 5'-D(*CP*GP*TP*AP*CP*CP*CP*AP*TP*TP*AP*AP*TP*GP*GP*GP*TP*AP*CP*G)-3', Nitrate/Nitrite Response Regulator Protein NARL, SULFATE ION
著者Maris, A.E, Sawaya, M.R, Kaczor-Grzeskowiak, M, Jarvis, M.R, Bearson, S.M.D, Kopka, M.L, Schroder, I, Gunsalus, R.P, Dickerson, R.E.
登録日2001-06-15
公開日2002-09-27
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Dimerization allows DNA target site recognition by the NarL response regulator.
Nat.Struct.Biol., 9, 2002
4Q5Y
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Crystal structure of extended-Tudor 10-11 of Drosophila melanogaster
分子名称: Maternal protein tudor
著者Liu, H, Ren, R, Wang, W, Wang, M, Yang, N, Dong, Y, Gong, W, Lehmann, R, Xu, R.M.
登録日2014-04-18
公開日2014-05-21
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure and domain organization of Drosophila Tudor
Cell Res., 24, 2014
4MC8
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Hedycaryol synthase in complex with HEPES
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Putative sesquiterpene cyclase
著者Baer, P, Rabe, P, Cirton, C, Oliveira Mann, C, Kaufmann, N, Groll, M, Dickschat, J.
登録日2013-08-21
公開日2014-01-29
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Hedycaryol synthase in complex with nerolidol reveals terpene cyclase mechanism.
Chembiochem, 15, 2014
4M9I
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A125C NS2B-NS3 protease from dengue virus at pH 5.5
分子名称: NS2B-NS3 protease
著者Yildiz, M, Hardy, J.A.
登録日2013-08-14
公開日2013-11-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Allosteric Inhibition of the NS2B-NS3 Protease from Dengue Virus.
Acs Chem.Biol., 8, 2013
1JFI
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Crystal Structure of the NC2-TBP-DNA Ternary Complex
分子名称: 5'-D(*G*GP*AP*GP*CP*CP*CP*TP*TP*TP*TP*AP*TP*AP*GP*CP*CP*AP*A)-3', 5'-D(*TP*TP*GP*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*GP*GP*CP*TP*CP*C)-3', TATA-BOX-BINDING PROTEIN (TBP), ...
著者Kamada, K, Shu, F, Chen, H, Malik, S, Stelzer, G, Roeder, R.G, Meisterernst, M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2001-06-20
公開日2001-07-11
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Crystal structure of negative cofactor 2 recognizing the TBP-DNA transcription complex.
Cell(Cambridge,Mass.), 106, 2001
3ZST
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GlgE isoform 1 from Streptomyces coelicolor with alpha-cyclodextrin bound
分子名称: 1,2-ETHANEDIOL, Cyclohexakis-(1-4)-(alpha-D-glucopyranose), PUTATIVE GLUCANOHYDROLASE PEP1A GLGE ISOFORM 1
著者Syson, K, Stevenson, C.E.M, Rejzek, M, Fairhurst, S.A, Nair, A, Bruton, C.J, Field, R.A, Chater, K.F, Lawson, D.M, Bornemann, S.
登録日2011-06-30
公開日2011-09-14
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of a Streptomyces Maltosyltransferase Glge: A Homologue of a Genetically Validated Anti-Tuberculosis Target.
J.Biol.Chem., 286, 2011
4MDT
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Structure of LpxC bound to the reaction product UDP-(3-O-(R-3-hydroxymyristoyl))-glucosamine
分子名称: PHOSPHATE ION, UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase, ZINC ION, ...
著者Clayton, G.M, Klein, D.J, Rickert, K.W, Patel, S.B, Kornienko, M, Zugay-Murphy, J, Reid, J.C, Tummala, S, Sharma, S, Singh, S.B, Miesel, L, Lumb, K.J, Soisson, S.M.
登録日2013-08-23
公開日2013-10-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Structure of the Bacterial Deacetylase LpxC Bound to the Nucleotide Reaction Product Reveals Mechanisms of Oxyanion Stabilization and Proton Transfer.
J.Biol.Chem., 288, 2013
4MEL
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Crystal Structure of the human USP11 DUSP-UBL domains
分子名称: Ubiquitin carboxyl-terminal hydrolase 11
著者Harper, S, Gratton, H.E, Cornaciu, I, Oberer, M, Scott, D.J, Emsley, J, Dreveny, I.
登録日2013-08-27
公開日2014-05-07
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.899 Å)
主引用文献Structure and Catalytic Regulatory Function of Ubiquitin Specific Protease 11 N-Terminal and Ubiquitin-like Domains.
Biochemistry, 53, 2014
3SEW
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BU of 3sew by Molmil
Zn-mediated Polymer of Maltose-binding Protein A216H/K220H by Synthetic Symmetrization (Form I)
分子名称: CHLORIDE ION, GLYCEROL, Maltose-binding periplasmic protein, ...
著者Zhao, M, Soriaga, A.B, Laganowsky, A, Sawaya, M.R, Cascio, D, Yeates, T.O.
登録日2011-06-11
公開日2011-09-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
3GG0
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Klebsiella pneumoniae BlrP1 pH 9.0 manganese/cy-diGMP complex
分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), FLAVIN MONONUCLEOTIDE, Klebsiella pneumoniae BlrP1, ...
著者Barends, T, Hartmann, E, Griese, J, Beitlich, T, Kirienko, N, Ryjenkov, D, Reinstein, J, Shoeman, R, Gomelsky, M, Schlichting, I.
登録日2009-02-27
公開日2009-06-23
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structure and mechanism of a bacterial light-regulated cyclic nucleotide phosphodiesterase.
Nature, 459, 2009
4Q7F
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1.98 Angstrom Crystal Structure of Putative 5'-Nucleotidase from Staphylococcus aureus in complex with Adenosine.
分子名称: (2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-tetrahydro-2-(hydroxymethyl)furan-3-ol, 5' nucleotidase family protein, MAGNESIUM ION, ...
著者Minasov, G, Nocadello, S, Shuvalova, L, Dubrovska, I, Winsor, J, Bagnoli, F, Falugi, F, Bottomley, M, Grandi, G, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2014-04-24
公開日2014-05-07
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献1.98 Angstrom Crystal Structure of Putative 5'-Nucleotidase from Staphylococcus aureus in complex with Adenosine.
TO BE PUBLISHED
4Q6B
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Crystal Structure of ABC Transporter Substrate-Binding Protein fromDesulfitobacterium hafniense complex with Leu
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, Extracellular ligand-binding receptor, ...
著者Kim, Y, Chhor, G, Endres, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2014-04-22
公開日2014-07-02
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.667 Å)
主引用文献Crystal Structure of ABC Transporter Substrate-Binding Protein fromDesulfitobacterium hafniense complex with Leu
To be Published, 2014
4MGB
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Crystal structure of hERa-LBD (Y537S) in complex with TCBPA
分子名称: 4,4'-propane-2,2-diylbis(2,6-dichlorophenol), Estrogen receptor, GLYCEROL, ...
著者Delfosse, V, Grimaldi, M, Bourguet, W.
登録日2013-08-28
公開日2014-09-03
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural and functional profiling of environmental ligands for estrogen receptors.
Environ.Health Perspect., 122, 2014
3SGD
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Crystal structure of the mouse mAb 17.2
分子名称: CALCIUM ION, Heavy Chain, Light Chain
著者Pizarro, J.C, Boulot, G, Hontebeyrie, M, Bentley, G.A.
登録日2011-06-14
公開日2011-11-09
最終更新日2013-01-23
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Crystal structure of the complex mAb 17.2 and the C-terminal region of Trypanosoma cruzi P2 Beta protein: implications in cross-reactivity
Plos Negl Trop Dis, 5, 2011
3GH7
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Crystal structure of beta-hexosaminidase from Paenibacillus sp. TS12 in complex with GalNAc
分子名称: 2-acetamido-2-deoxy-beta-D-galactopyranose, SULFATE ION, beta-hexosaminidase
著者Sumida, T, Ishii, R, Yanagisawa, T, Yokoyama, S, Ito, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2009-03-03
公開日2009-07-07
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Molecular cloning and crystal structural analysis of a novel beta-N-acetylhexosaminidase from Paenibacillus sp. TS12 capable of degrading glycosphingolipids
J.Mol.Biol., 392, 2009
4MHG
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Crystal structure of ETV6 bound to a specific DNA sequence
分子名称: Complementary Specific 14 bp DNA, Specific 14 bp DNA, Transcription factor ETV6
著者Chan, A.C, De, S, Coyne III, H.J, Okon, M, Murphy, M.E, Graves, B.J, McIntosh, L.P.
登録日2013-08-29
公開日2014-01-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.199 Å)
主引用文献Steric Mechanism of Auto-Inhibitory Regulation of Specific and Non-Specific DNA Binding by the ETS Transcriptional Repressor ETV6.
J.Mol.Biol., 426, 2014
4Q8P
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tRNA-Guanine Transglycosylase (TGT) Mutant V262D in Complex with 6-Amino-2-{[2-(morpholin-4-yl)ethyl]amino}-1H,7H,8H-imidazo[4,5-g]quinazolin-8-one
分子名称: 6-amino-2-[(2-morpholin-4-ylethyl)amino]-3,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one, GLYCEROL, Queuine tRNA-ribosyltransferase, ...
著者Neeb, M, Heine, A, Klebe, G.
登録日2014-04-28
公開日2015-05-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Creating a Resistance Model for TGT: The Effect of Mutations on Flexible lin-Benzoguanine Substituents
To be Published
3GH4
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Crystal structure of beta-hexosaminidase from Paenibacillus sp. TS12
分子名称: ACETIC ACID, SULFATE ION, beta-hexosaminidase
著者Sumida, T, Ishii, R, Yanagisawa, T, Yokoyama, S, Ito, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2009-03-03
公開日2009-07-07
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Molecular cloning and crystal structural analysis of a novel beta-N-acetylhexosaminidase from Paenibacillus sp. TS12 capable of degrading glycosphingolipids
J.Mol.Biol., 392, 2009
3SJ0
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PpcA mutant M58S
分子名称: (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, CYTOCHROME C7, HEME C, ...
著者Pokkuluri, P.R, Schiffer, M.
登録日2011-06-20
公開日2012-07-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Pitfalls in the interpretation of structural changes in mutant proteins from crystal structures.
J.Struct.Funct.Genom., 13, 2012
3SJ4
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PpcA mutant M58K
分子名称: (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, CYTOCHROME C7, HEME C, ...
著者Pokkuluri, P.R, Schiffer, M.
登録日2011-06-20
公開日2012-07-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Pitfalls in the interpretation of structural changes in mutant proteins from crystal structures.
J.Struct.Funct.Genom., 13, 2012

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件を2024-10-09に公開中

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