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PDB: 51689 件

5BYZ
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ERK5 in complex with small molecule
分子名称: 4-({5-fluoro-4-[2-methyl-1-(propan-2-yl)-1H-imidazol-5-yl]pyrimidin-2-yl}amino)-N-[2-(piperidin-1-yl)ethyl]benzamide, GLYCEROL, Mitogen-activated protein kinase 7
著者Chen, H, Tucker, J, Wang, X, Gavine, P.R, Philips, C, Augustin, M.A, Schreiner, P, Steinbacher, S, Preston, M, Ogg, D.
登録日2015-06-11
公開日2016-05-04
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Discovery of a novel allosteric inhibitor-binding site in ERK5: comparison with the canonical kinase hinge ATP-binding site.
Acta Crystallogr D Struct Biol, 72, 2016
5C0U
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Crystal structure of the copper-bound form of MerB mutant D99S
分子名称: Alkylmercury lyase, BROMIDE ION, COPPER (II) ION
著者Wahba, H.M, Lecoq, L, Stevenson, M, Mansour, A, Cappadocia, L, Lafrance-Vanasse, J, Wilkinson, K.J, Sygusch, J, Wilcox, D.E, Omichinski, J.G.
登録日2015-06-12
公開日2016-02-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Structural and Biochemical Characterization of a Copper-Binding Mutant of the Organomercurial Lyase MerB: Insight into the Key Role of the Active Site Aspartic Acid in Hg-Carbon Bond Cleavage and Metal Binding Specificity.
Biochemistry, 55, 2016
1K1B
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Crystal structure of the ankyrin repeat domain of Bcl-3: a unique member of the IkappaB protein family
分子名称: B-cell lymphoma 3-encoded protein
著者Michel, F, Soler-Lopez, M, Petosa, C, Cramer, P, Siebenlist, U, Mueller, C.W.
登録日2001-09-24
公開日2001-11-21
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the ankyrin repeat domain of Bcl-3: a unique member of the IkappaB protein family.
EMBO J., 20, 2001
6JAO
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Crystal structure of ABC transporter alpha-glycoside-binding mutant protein R356A in complex with palatinose
分子名称: 1,2-ETHANEDIOL, ABC transporter, periplasmic substrate-binding protein, ...
著者Kanaujia, S.P, Chandravanshi, M, Gogoi, P.
登録日2019-01-24
公開日2019-10-30
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Structural and thermodynamic correlation illuminates the selective transport mechanism of disaccharide alpha-glycosides through ABC transporter.
Febs J., 287, 2020
4LHQ
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Ricin A chain bound to camelid nanobody (VHH8)
分子名称: Camelid nanobody, Ricin
著者Rudolph, M.J, Cheung, J, Franklin, M, Burshteyn, F, Cassidy, M, Gary, E, Mantis, N.
登録日2013-07-01
公開日2014-06-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structures of Ricin Toxin's Enzymatic Subunit (RTA) in Complex with Neutralizing and Non-Neutralizing Single-Chain Antibodies.
J.Mol.Biol., 426, 2014
1K1W
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Crystal structure of 4-alpha-glucanotransferase from thermococcus litoralis
分子名称: 4-ALPHA-GLUCANOTRANSFERASE, CALCIUM ION, SULFATE ION, ...
著者Imamura, H, Fushinobu, S, Kumasaka, T, Yamamoto, M, Jeon, B.S, Wakagi, T, Matsuzawa, H.
登録日2001-09-26
公開日2003-06-17
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structures of 4-alpha-glucanotransferase from Thermococcus litoralis and its complex with an inhibitor
J.BIOL.CHEM., 278, 2003
3NXZ
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Crystal Structure of UreE from Helicobacter pylori (Cu2+ bound form)
分子名称: COPPER (II) ION, Urease accessory protein ureE
著者Shi, R, Munger, C, Assinas, A, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
登録日2010-07-14
公開日2010-08-25
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal Structures of Apo and Metal-Bound Forms of the UreE Protein from Helicobacter pylori: Role of Multiple Metal Binding Sites
Biochemistry, 49, 2010
7Z1X
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Crystal structure of human Gasdermin D complexed with nanobodies VHH-2 and VHH-6
分子名称: Gasdermin-D, VHH-2, VHH-6
著者Kopp, A, Hagelueken, G, Geyer, M.
登録日2022-02-25
公開日2023-09-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Pyroptosis inhibiting nanobodies block Gasdermin D pore formation.
Nat Commun, 14, 2023
6EWI
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Oreochromis niloticus CEP120 second C2 domain (C2B) A200P + G307S mutant
分子名称: Centrosomal protein 120
著者van Breugel, M.
登録日2017-11-04
公開日2018-05-02
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Disease-Associated Mutations in CEP120 Destabilize the Protein and Impair Ciliogenesis.
Cell Rep, 23, 2018
1JJH
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E2 DNA-binding Domain from Bovine Papillomavirus Type 1
分子名称: REGULATORY PROTEIN E2
著者Hegde, R.S, Wang, A.F, Kim, S.S, Schapira, M.
登録日2001-07-05
公開日2001-07-18
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Subunit rearrangement accompanies sequence-specific DNA binding by the bovine papillomavirus-1 E2 protein.
J.Mol.Biol., 276, 1998
4LJB
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Structure of a photobleached state of IrisFP under high intensity laser-light
分子名称: Green to red photoconvertible GPF-like protein EosFP, SULFATE ION, SULFITE ION
著者Duan, C, Adam, V, Byrdin, M, Ridard, J, Kieffer-Jacquinod, S, Morlot, C, Arcizet, D, Demachy, I, Bourgeois, D.
登録日2013-07-04
公開日2013-10-09
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9019 Å)
主引用文献Structural evidence for a two-regime photobleaching mechanism in a reversibly switchable fluorescent protein.
J.Am.Chem.Soc., 135, 2013
7YLB
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Two monobodies recognizing the conserved epitopes of SARS-CoV-2 N antigen applicable to the broad COVID-19 diagnosis
分子名称: NC2, Nucleoprotein, SULFATE ION
著者Hu, M, Du, Y, Sun, R, Hao, Q.
登録日2022-07-26
公開日2023-09-06
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Two monobodies recognizing the conserved epitopes of SARS-CoV-2 N antigen applicable to the broad COVID-19 diagnosis
To Be Published
5C5Y
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Crystal structure of deoxyribose-phosphate aldolase from Colwellia psychrerythraea (hexagonal form)
分子名称: Deoxyribose-phosphate aldolase, GLYCEROL, UNKNOWN LIGAND
著者Weiergraeber, O.H, Dick, M, Pietruszka, J.
登録日2015-06-22
公開日2016-02-03
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Trading off stability against activity in extremophilic aldolases.
Sci Rep, 6, 2016
6EWP
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Mus musculus CEP120 third C2 domain (C2C)
分子名称: Centrosomal protein of 120 kDa, HEXAETHYLENE GLYCOL
著者van Breugel, M, al-Jassar, C.
登録日2017-11-06
公開日2018-05-02
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Disease-Associated Mutations in CEP120 Destabilize the Protein and Impair Ciliogenesis.
Cell Rep, 23, 2018
4LIX
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BU of 4lix by Molmil
Crystal structure of ent-copalyl diphosphate synthase from Arabidopsis thaliana in complex with (S)-15-aza-14,15-dihydrogeranylgeranyl thiolodiphosphate at 1.55 A resolution
分子名称: Ent-copalyl diphosphate synthase, chloroplastic, GLYCEROL, ...
著者Koksal, M, Christianson, D.W.
登録日2013-07-04
公開日2013-10-02
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.548 Å)
主引用文献1.55 angstrom -resolution structure of ent-copalyl diphosphate synthase and exploration of general acid function by site-directed mutagenesis.
Biochim.Biophys.Acta, 1840, 2013
3NSL
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Crystal Structure of S100A3 C30A+C68A double mutant expressed in insect cell
分子名称: GLYCEROL, Protein S100-A3
著者Unno, M, Takahara, H, Kizawa, K.
登録日2010-07-02
公開日2011-03-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Refined crystal structures of human Ca(2+)/Zn(2+)-binding S100A3 protein characterized by two disulfide bridges
J.Mol.Biol., 408, 2011
1JSE
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FULL-MATRIX LEAST-SQUARES REFINEMENT OF TURKEY LYSOZYME
分子名称: LYSOZYME, N-PROPANOL
著者Harata, K, Abe, Y, Muraki, M.
登録日1998-01-05
公開日1998-04-29
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.12 Å)
主引用文献Full-matrix least-squares refinement of lysozymes and analysis of anisotropic thermal motion.
Proteins, 30, 1998
6EZC
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Crystal Structure of human tRNA-dihydrouridine(20) synthase catalytic domain E294K Q305K double mutant
分子名称: CHLORIDE ION, FLAVIN MONONUCLEOTIDE, GLYCEROL, ...
著者Bou-Nader, C, Bregeon, D, Vincent, G, Fontecave, M, Hamdane, D.
登録日2017-11-14
公開日2018-09-26
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Electrostatic Potential in the tRNA Binding Evolution of Dihydrouridine Synthases.
Biochemistry, 57, 2018
5C4J
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Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble
分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
著者Barnes, C.O, Calero, M, Malik, I, Spahr, H, Zhang, Q, Pullara, F, Kaplan, C.D, Calero, G.
登録日2015-06-18
公開日2015-08-26
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble.
Mol.Cell, 59, 2015
2BZL
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CRYSTAL STRUCTURE OF THE HUMAN PROTEIN TYROSINE PHOSPHATASE N14 AT 1. 65 A RESOLUTION
分子名称: 1,2-ETHANEDIOL, SULFATE ION, TYROSINE-PROTEIN PHOSPHATASE, ...
著者Debreczeni, J.E, Barr, A, Eswaran, J, Das, S, Burgess, N, Longman, E, Fedorov, O, Gileadi, O, von Delft, F, Sundstrom, M, Arrowsmith, C, Weigelt, J, Edwards, A, Knapp, S.
登録日2005-08-18
公開日2005-09-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal Structure of Human Protein Tyrosine Phosphatase 14 (Ptpn14) at 1.65-A Resolution.
Proteins, 63, 2006
6JG1
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Crystal structure of barley exohydrolaseI wildtype in complex with 4I,4III,4V-S-trithiocellohexaose
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Barley exohydrolase I, GLYCEROL, ...
著者Luang, S, Streltsov, V.A, Hrmova, M.
登録日2019-02-13
公開日2020-08-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献The evolutionary advantage of an aromatic clamp in plant family 3 glycoside exo-hydrolases.
Nat Commun, 13, 2022
6JGB
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Crystal structure of barley exohydrolaseI W286F mutant in complex with methyl 6-thio-beta-gentiobioside
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, BETA-D-GLUCAN GLUCOHYDROLASE ISOENZYME EXO1, ...
著者Luang, S, Streltsov, V.A, Hrmova, M.
登録日2019-02-13
公開日2020-08-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献The evolutionary advantage of an aromatic clamp in plant family 3 glycoside exo-hydrolases.
Nat Commun, 13, 2022
6JGG
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Crystal structure of barley exohydrolaseI W434F mutant in complex with methyl 2-thio-beta-sophoroside.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, BETA-D-GLUCAN GLUCOHYDROLASE ISOENZYME EXO1, ...
著者Luang, S, Streltsov, V.A, Hrmova, M.
登録日2019-02-14
公開日2020-08-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The evolutionary advantage of an aromatic clamp in plant family 3 glycoside exo-hydrolases.
Nat Commun, 13, 2022
6F0U
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GLIC mutant E35A
分子名称: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
著者Hu, H.D, Delarue, M.
登録日2017-11-20
公開日2018-01-10
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Full mutational mapping of titratable residues helps to identify proton-sensors involved in the control of channel gating in the Gloeobacter violaceus pentameric ligand-gated ion channel.
PLoS Biol., 15, 2017
6JGQ
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Crystal structure of barley exohydrolaseI W434Y mutant in complex with methyl 2-thio-beta-sophoroside.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, BETA-D-GLUCAN GLUCOHYDROLASE ISOENZYME EXO1, GLYCEROL, ...
著者Luang, S, Streltsov, V.A, Hrmova, M.
登録日2019-02-14
公開日2020-08-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献The evolutionary advantage of an aromatic clamp in plant family 3 glycoside exo-hydrolases.
Nat Commun, 13, 2022

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