6H2G
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6FAM
| Structure of the GH99 endo-alpha-mannanase from Bacteroides xylanisolvens in complex with mannose-alpha-1,3-2-aminodeoxymannojirimycin | 分子名称: | ACETATE ION, Glycosyl hydrolase family 71, alpha-D-mannopyranose, ... | 著者 | Fernandes, P.Z, Petricevic, M, Sobala, L.F, Davies, G.J, Williams, S.J. | 登録日 | 2017-12-15 | 公開日 | 2018-03-21 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.13 Å) | 主引用文献 | Exploration of Strategies for Mechanism-Based Inhibitor Design for Family GH99 endo-alpha-1,2-Mannanases. Chemistry, 24, 2018
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1HJP
| HOLLIDAY JUNCTION BINDING PROTEIN RUVA FROM E. COLI | 分子名称: | RUVA | 著者 | Nishino, T, Ariyoshi, M, Iwasaki, H, Shinagawa, H, Morikawa, K. | 登録日 | 1997-08-21 | 公開日 | 1998-02-25 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Functional Analyses of the Domain Structure in the Holliday Junction Binding Protein Ruva Structure, 6, 1998
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3DPU
| RocCOR domain tandem of Rab family protein (Roco) | 分子名称: | Rab family protein | 著者 | Gotthardt, K, Weyand, M, Kortholt, A, Van Haastert, P.J.M, Wittinghofer, A. | 登録日 | 2008-07-09 | 公開日 | 2008-08-12 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structure of the Roc-COR domain tandem of C. tepidum, a prokaryotic homologue of the human LRRK2 Parkinson kinase Embo J., 27, 2008
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3DQV
| Structural Insights into NEDD8 Activation of Cullin-RING Ligases: Conformational Control of Conjugation | 分子名称: | Cullin-5, NEDD8, Rbx1, ... | 著者 | Duda, D.M, Borg, L.A, Scott, D.C, Hunt, H.W, Hammel, M, Schulman, B.A. | 登録日 | 2008-07-09 | 公開日 | 2008-09-30 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation. Cell(Cambridge,Mass.), 134, 2008
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6H2U
| Crystal structure of human METTL5-TRMT112 complex, the 18S rRNA m6A1832 methyltransferase at 1.6A resolution | 分子名称: | 1,2-ETHANEDIOL, Methyltransferase-like protein 5, Multifunctional methyltransferase subunit TRM112-like protein, ... | 著者 | van Tran, N, Graille, M. | 登録日 | 2018-07-16 | 公開日 | 2019-07-31 | 最終更新日 | 2019-09-18 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | The human 18S rRNA m6A methyltransferase METTL5 is stabilized by TRMT112. Nucleic Acids Res., 47, 2019
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4NBZ
| Crystal Structure of TcdA-A1 Bound to A26.8 VHH | 分子名称: | A26.8 VHH, TcdA | 著者 | Murase, T, Eugenio, L, Schorr, M, Hussack, G, Tanha, J, Kitova, E.N, Klassen, J.S, Ng, K.K.S. | 登録日 | 2013-10-23 | 公開日 | 2013-12-11 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural Basis for Antibody Recognition in the Receptor-binding Domains of Toxins A and B from Clostridium difficile. J.Biol.Chem., 289, 2014
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4NC9
| Crystal structure of phosphatidyl mannosyltransferase PimA | 分子名称: | GDP-mannose-dependent alpha-(1-2)-phosphatidylinositol mannosyltransferase | 著者 | Giganti, D, Albesa-Jove, D, Bellinzoni, M, Guerin, M.E, Alzari, P.M. | 登録日 | 2013-10-24 | 公開日 | 2014-11-12 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.192 Å) | 主引用文献 | Secondary structure reshuffling modulates glycosyltransferase function at the membrane. Nat.Chem.Biol., 11, 2015
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1HM4
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4NCY
| In situ trypsin crystallized on a MiTeGen micromesh with imidazole ligand | 分子名称: | 1,2-ETHANEDIOL, BENZAMIDINE, CALCIUM ION, ... | 著者 | Yin, X, Scalia, A, Leroy, L, Cuttitta, C.M, Polizzo, G.M, Ericson, D.L, Roessler, C.G, Campos, O, Agarwal, R, Allaire, M, Orville, A.M, Jackimowicz, R, Ma, M.Y, Sweet, R.M, Soares, A.S. | 登録日 | 2013-10-25 | 公開日 | 2014-04-09 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | 主引用文献 | Hitting the target: fragment screening with acoustic in situ co-crystallization of proteins plus fragment libraries on pin-mounted data-collection micromeshes. Acta Crystallogr.,Sect.D, 70, 2014
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3Q1H
| Crystal Structure of Dihydrofolate Reductase from Yersinia pestis | 分子名称: | Dihydrofolate reductase, SULFATE ION | 著者 | Maltseva, N, Kim, Y, Makowska-Grzyska, M, Mulligan, R, Papazisi, L, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2010-12-17 | 公開日 | 2011-01-12 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.804 Å) | 主引用文献 | Crystal Structure of Dihydrofolate Reductase from Yersinia pestis To be Published
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6H3U
| Schmallenberg Virus Glycoprotein Gc Head Domain in Complex with scFv 4B6 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Envelopment polyprotein, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Hellert, J, Aebischer, A, Wernike, K, Haouz, A, Brocchi, E, Reiche, S, Guardado-Calvo, P, Beer, M, Rey, F.A. | 登録日 | 2018-07-19 | 公開日 | 2019-02-27 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.168 Å) | 主引用文献 | Orthobunyavirus spike architecture and recognition by neutralizing antibodies. Nat Commun, 10, 2019
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6GUD
| Siderophore hydrolase EstB from Aspergillus fumigatus | 分子名称: | CARBONATE ION, GLYCEROL, SULFATE ION, ... | 著者 | Ecker, F, Haas, H, Groll, M, Huber, E.M. | 登録日 | 2018-06-19 | 公開日 | 2018-08-15 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Iron Scavenging in Aspergillus Species: Structural and Biochemical Insights into Fungal Siderophore Esterases. Angew. Chem. Int. Ed. Engl., 57, 2018
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6GUN
| Siderophore hydrolase EstB from Aspergillus nidulans | 分子名称: | EstB from Aspergillus nidulans, GLYCEROL | 著者 | Ecker, F, Haas, H, Groll, M, Huber, E.M. | 登録日 | 2018-06-19 | 公開日 | 2018-08-15 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Iron Scavenging in Aspergillus Species: Structural and Biochemical Insights into Fungal Siderophore Esterases. Angew. Chem. Int. Ed. Engl., 57, 2018
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3Q4Y
| Crystal structure of group I phospholipase A2 at 2.3 A resolution in 40% ethanol revealed the critical elements of hydrophobicity of the substrate-binding site | 分子名称: | CALCIUM ION, ETHANOL, Phospholipase A2 isoform 3 | 著者 | Shukla, P.K, Kaushik, S, Sinha, M, Kaur, P, Sharma, S, Singh, T.P. | 登録日 | 2010-12-26 | 公開日 | 2011-01-26 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of group I phospholipase A2 at 2.3 A resolution in 40% ethanol revealed the critical elements of hydrophobicity of the substrate-binding site To be Published
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3DOI
| Crystal Structure of a Thermostable Esterase complex with paraoxon | 分子名称: | DIETHYL PHOSPHONATE, esterase | 著者 | Levisson, M, Sun, L, Hendriks, S, Dijkstra, B.W, Van der Oost, J, Kengen, S.W.M. | 登録日 | 2008-07-04 | 公開日 | 2009-02-17 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal structure and biochemical properties of a novel thermostable esterase containing an immunoglobulin-like domain. J.Mol.Biol., 385, 2009
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4NE7
| Crystal Structure of engineered Kumamolisin-As from Alicyclobacillus sendaiensis, Northeast Structural Genomics Consortium (NESG) Target OR367 | 分子名称: | Kumamolisin-As, ZINC ION | 著者 | Guan, R, Pultz, I.S, Siegel, J.B, Seetharaman, J, Kornhaber, G, Maglaqui, M, Mao, L, Xiao, R, Everett, J.K, Baker, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2013-10-28 | 公開日 | 2013-11-20 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.497 Å) | 主引用文献 | Northeast Structural Genomics Consortium Target OR367 To be Published
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6GWE
| Crystal structure of Thrombin bound to P2 macrocycle | 分子名称: | (10S,14S,17R)-14-(3-carbamimidamidopropyl)-3-[[2-(hydroxymethyl)phenyl]methyl]-5,12,15-tris(oxidanylidene)-19-thia-3,6,13,16-tetrazatricyclo[19.4.0.0^{6,10}]pentacosa-1(21),22,24-triene-17-carboxamide, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Cendron, L, Angelini, A, Kale, S.S, Bergeron-Brlek, M, Wu, Y, Heinis, C. | 登録日 | 2018-06-23 | 公開日 | 2019-09-25 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Thiol-to-amine cyclization reaction enables screening of large libraries of macrocyclic compounds and the generation of sub-kilodalton ligands. Sci Adv, 5, 2019
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2C30
| Crystal Structure Of The Human P21-Activated Kinase 6 | 分子名称: | CHLORIDE ION, PHOSPHATE ION, SERINE/THREONINE-PROTEIN KINASE PAK 6 | 著者 | Filippakopoulos, P, Berridge, G, Bray, J, Burgess, N, Colebrook, S, Das, S, Eswaran, J, Gileadi, O, Papagrigoriou, E, Savitsky, P, Smee, C, Turnbull, A, Sundstrom, M, Arrowsmith, C, Weigelt, J, Edwards, A, von Delft, F, Knapp, S. | 登録日 | 2005-10-02 | 公開日 | 2006-02-08 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal Structures of the P21-Activated Kinases Pak4, Pak5, and Pak6 Reveal Catalytic Domain Plasticity of Active Group II Paks. Structure, 15, 2007
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6FDL
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4YDZ
| Stress-induced protein 1 from Caenorhabditis elegans | 分子名称: | Stress-induced protein 1 | 著者 | Fleckenstein, T, Kastenmueller, A, Stein, M.L, Peters, C, Daake, M, Krause, M, Weinfurtner, D, Haslbeck, M, Weinkauf, S, Groll, M, Buchner, J. | 登録日 | 2015-02-23 | 公開日 | 2015-06-10 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | The Chaperone Activity of the Developmental Small Heat Shock Protein Sip1 Is Regulated by pH-Dependent Conformational Changes. Mol.Cell, 58, 2015
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4NNN
| yCP in complex with MG132 | 分子名称: | MAGNESIUM ION, N-[(benzyloxy)carbonyl]-L-leucyl-N-[(2S)-1-hydroxy-4-methylpentan-2-yl]-L-leucinamide, Probable proteasome subunit alpha type-7, ... | 著者 | Stein, M.L, Cui, H, Beck, P, Dubiella, C, Voss, C, Krueger, A, Schmidt, B, Groll, M. | 登録日 | 2013-11-18 | 公開日 | 2014-02-12 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Systematic Comparison of Peptidic Proteasome Inhibitors Highlights the alpha-Ketoamide Electrophile as an Auspicious Reversible Lead Motif. Angew.Chem.Int.Ed.Engl., 53, 2014
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3DPT
| COR domain of Rab family protein (Roco) | 分子名称: | Rab family protein | 著者 | Gotthardt, K, Weyand, M, Kortholt, A, Van Haastert, P.J.M, Wittinghofer, A. | 登録日 | 2008-07-09 | 公開日 | 2008-08-12 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structure of the Roc-COR domain tandem of C. tepidum, a prokaryotic homologue of the human LRRK2 Parkinson kinase Embo J., 27, 2008
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4NP6
| Crystal Structure of Adenylate Kinase from Vibrio cholerae O1 biovar eltor | 分子名称: | Adenylate kinase | 著者 | Kim, Y, Zhou, M, Grimshaw, S, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2013-11-20 | 公開日 | 2013-12-18 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (2.004 Å) | 主引用文献 | Crystal Structure of Adenylate Kinase from Vibrio cholerae O1 biovar eltor To be Published
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6GYE
| Crystal structure of NadR protein in complex with NR | 分子名称: | Nicotinamide riboside, Nicotinamide-nucleotide adenylyltransferase NadR family / Ribosylnicotinamide kinase, SULFATE ION | 著者 | Singh, R, Stetsenko, A, Jaehme, M, Guskov, A, Slotboom, D.J. | 登録日 | 2018-06-29 | 公開日 | 2019-07-10 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural and Functional Characterization of NadR fromLactococcus lactis. Molecules, 25, 2020
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