7LFZ
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6SJG
| Cryo-EM structure of the RecBCD no Chi negative control complex | 分子名称: | Forked DNA substrate, RecBCD enzyme subunit RecB, RecBCD enzyme subunit RecC, ... | 著者 | Cheng, K, Wilkinson, M, Wigley, D.B. | 登録日 | 2019-08-13 | 公開日 | 2020-01-01 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | A conformational switch in response to Chi converts RecBCD from phage destruction to DNA repair. Nat.Struct.Mol.Biol., 27, 2020
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7LCX
| Wild-type Pseudomonas fluorescens isocyanide hydratase (WT-3) at 274K, Phenix-refined | 分子名称: | Isonitrile hydratase InhA | 著者 | Su, Z, Dasgupta, M, Yoon, C.H, Wilson, M.A. | 登録日 | 2021-01-12 | 公開日 | 2021-02-03 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Reproducibility of protein x-ray diffuse scattering and potential utility for modeling atomic displacement parameters. Struct Dyn., 8, 2021
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1X6A
| Solution structures of the second LIM domain of human LIM-kinase 2 (LIMK2) | 分子名称: | LIM domain kinase 2, ZINC ION | 著者 | Nameki, N, Sasagawa, A, Tomizawa, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2005-05-17 | 公開日 | 2005-11-17 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structures of the second LIM domain of human LIM-kinase 2 (LIMK2) To be Published
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6SL0
| Complete CtTel1 dimer with C2 symmetry | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase Tel1 | 著者 | Jansma, M, Eustermann, S.E, Kostrewa, D, Lammens, K, Hopfner, K.P. | 登録日 | 2019-08-16 | 公開日 | 2019-10-30 | 最終更新日 | 2020-01-15 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Near-Complete Structure and Model of Tel1ATM from Chaetomium thermophilum Reveals a Robust Autoinhibited ATP State. Structure, 28, 2020
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6SLV
| Fragment AZ-013 binding at the p53pT387/14-3-3 sigma interface | 分子名称: | 14-3-3 protein sigma, 4-(methylamino)-7-propan-2-yloxy-1-benzothiophene-2-carboximidamide, CHLORIDE ION, ... | 著者 | Ottmann, C, Wolter, M, Guillory, X, Leysen, S, Genet, S, Somsen, B, Patel, J, Castaldi, P. | 登録日 | 2019-08-20 | 公開日 | 2020-06-17 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Fragment-based Differential Targeting of PPI Stabilizer Interfaces. J.Med.Chem., 63, 2020
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7LDB
| G150A Pseudomonas fluorescens isocyanide hydratase (G150A-3) at 274K, Phenix-refined | 分子名称: | Isonitrile hydratase InhA | 著者 | Su, Z, Dasgupta, M, Yoon, C.H, Wilson, M.A. | 登録日 | 2021-01-13 | 公開日 | 2021-02-03 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Reproducibility of protein x-ray diffuse scattering and potential utility for modeling atomic displacement parameters. Struct Dyn., 8, 2021
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6SMN
| A. thaliana serine hydroxymethyltransferase isoform 2 (AtSHMT2) in complex with methotrexate | 分子名称: | 1,2-ETHANEDIOL, METHOTREXATE, SERINE, ... | 著者 | Ruszkowski, M, Sekula, B, Dauter, Z. | 登録日 | 2019-08-22 | 公開日 | 2020-01-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Structural basis of methotrexate and pemetrexed action on serine hydroxymethyltransferases revealed using plant models. Sci Rep, 9, 2019
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6SNK
| Crystal structure of the Collagen VI alpha3 N2 domain | 分子名称: | Collagen alpha-3(VI) chain | 著者 | Gebauer, J.M, Degefa, H.S, Paulsson, M, Wagener, R, Baumann, U. | 登録日 | 2019-08-26 | 公開日 | 2020-07-29 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of a collagen VI alpha 3 chain VWA domain array: adaptability and functional implications of myopathy causing mutations. J.Biol.Chem., 295, 2020
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6SNP
| Crystal structures of human PGM1 isoform 2 | 分子名称: | MAGNESIUM ION, Phosphoglucomutase-1 | 著者 | Backe, P.H, Laerdahl, J.K, Kittelsen, L.S, Dalhus, B, Morkrid, L, Bjoras, M. | 登録日 | 2019-08-27 | 公開日 | 2020-04-08 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Structural basis for substrate and product recognition in human phosphoglucomutase-1 (PGM1) isoform 2, a member of the alpha-D-phosphohexomutase superfamily. Sci Rep, 10, 2020
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7LG2
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5NTU
| Crystal Structure of human Pro-myostatin Precursor at 2.6 A Resolution | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Growth/differentiation factor 8 | 著者 | Cotton, T.R, Fischer, G, Hyvonen, M. | 登録日 | 2017-04-28 | 公開日 | 2018-01-17 | 最終更新日 | 2018-02-21 | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | 主引用文献 | Structure of the human myostatin precursor and determinants of growth factor latency. EMBO J., 37, 2018
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5NUB
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6SL9
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7LL8
| D-Protein RFX-V1 Bound to the VEGFR1 Domain 2 Site on VEGF-A | 分子名称: | Isoform L-VEGF189 of Vascular endothelial growth factor A, RFX-V1 | 著者 | Marinec, P.S, Landgraf, K.E, Uppalapati, M, Chen, G, Xie, D, Jiang, Q, Zhao, Y, Petriello, A, Deshayes, K, Kent, S.B.H, Ault-Riche, D, Sidhu, S.S. | 登録日 | 2021-02-03 | 公開日 | 2021-02-17 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | A Non-immunogenic Bivalent d-Protein Potently Inhibits Retinal Vascularization and Tumor Growth. Acs Chem.Biol., 16, 2021
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6SLE
| Structure of Reductive Aminase from Neosartorya fumigata in complex with NADP+ | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Oxidoreductase, putative | 著者 | Sharma, M, Mangas-Sanchez, J, Turner, N.J, Grogan, G. | 登録日 | 2019-08-19 | 公開日 | 2020-06-24 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.77 Å) | 主引用文献 | Asymmetric synthesis of primary amines catalyzed by thermotolerant fungal reductive aminases. Chem Sci, 11, 2020
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5NU8
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7LBN
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7LL9
| D-Protein RFX-V2 Bound to the VEGFR1 Domain 3 Site on VEGF-A | 分子名称: | Isoform L-VEGF189 of Vascular endothelial growth factor A, RFX-V2 | 著者 | Marinec, P.S, Landgraf, K.E, Uppalapati, M, Chen, G, Xie, D, Jiang, Q, Zhao, Y, Petriello, A, Deshayes, K, Kent, S.B.H, Ault-Riche, D, Sidhu, S.S. | 登録日 | 2021-02-03 | 公開日 | 2021-03-03 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | A Non-immunogenic Bivalent d-Protein Potently Inhibits Retinal Vascularization and Tumor Growth. Acs Chem.Biol., 16, 2021
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5NY1
| Carbonic Anhydrase II Inhibitor RA10 | 分子名称: | 3,6,7-trimethyl-~{N}-[(4-sulfamoylphenyl)methyl]-1-benzofuran-2-carboxamide, Carbonic anhydrase 2, ZINC ION | 著者 | Brynda, J, Rezacova, P, Horejsi, M, Fanfrlik, J. | 登録日 | 2017-05-11 | 公開日 | 2018-01-17 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Ranking Power of the SQM/COSMO Scoring Function on Carbonic Anhydrase II-Inhibitor Complexes. Chemphyschem, 19, 2018
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6SNO
| Crystal structures of human PGM1 isoform 2 | 分子名称: | 1-O-phosphono-alpha-D-glucopyranose, Phosphoglucomutase-1, ZINC ION | 著者 | Backe, P.H, Laerdahl, J.K, Kittelsen, L.S, Dalhus, B, Morkrid, L, Bjoras, M. | 登録日 | 2019-08-27 | 公開日 | 2020-04-08 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural basis for substrate and product recognition in human phosphoglucomutase-1 (PGM1) isoform 2, a member of the alpha-D-phosphohexomutase superfamily. Sci Rep, 10, 2020
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1XF0
| Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 5 (AKR1C3) complexed with delta4-androstene-3,17-dione and NADP | 分子名称: | 4-ANDROSTENE-3-17-DIONE, ACETATE ION, Aldo-keto reductase family 1 member C3, ... | 著者 | Qiu, W, Zhou, M, Labrie, F, Lin, S.-X. | 登録日 | 2004-09-13 | 公開日 | 2004-10-26 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structures of the multispecific 17beta-hydroxysteroid dehydrogenase type 5: critical androgen regulation in human peripheral tissues Mol.Endocrinol., 18, 2004
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1SI8
| Crystal structure of E. faecalis catalase | 分子名称: | CHLORIDE ION, Catalase, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Hakansson, K.O, Brugna, M, Tasse, L. | 登録日 | 2004-02-28 | 公開日 | 2004-05-04 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The three-dimensional structure of catalase from Enterococcus faecalis. Acta Crystallogr.,Sect.D, 60, 2004
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6SSP
| Structure of the pentameric ligand-gated ion channel ELIC in complex with a NAM nanobody | 分子名称: | CALCIUM ION, Cys-loop ligand-gated ion channel, NANOBODY 21, ... | 著者 | Ulens, C, Brams, M, Evans, G.L, Spurny, R, Govaerts, C, Pardon, E, Steyaert, J. | 登録日 | 2019-09-09 | 公開日 | 2020-02-12 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | Modulation of the Erwinia ligand-gated ion channel (ELIC) and the 5-HT 3 receptor via a common vestibule site. Elife, 9, 2020
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5NXL
| Formylglycine generating enzyme from T. curvata in complex with Ag(I) | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, CALCIUM ION, ... | 著者 | Meury, M, Knop, M, Seebeck, F.P. | 登録日 | 2017-05-10 | 公開日 | 2017-06-07 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | Structural Basis for Copper-Oxygen Mediated C-H Bond Activation by the Formylglycine-Generating Enzyme. Angew. Chem. Int. Ed. Engl., 56, 2017
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