7LBN

X-ray crystal structure of the SARS-CoV-2 main protease with Calpain I Inhibitor

Summary for 7LBN

Entry DOI	10.2210/pdb7lbn/pdb
Related PRD ID	PRD_002460
Descriptor	3C-like proteinase, Calpain I Inhibitor, SULFATE ION, ... (4 entities in total)
Functional Keywords	protease-inhibitor complex, viral protein
Biological source	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV,SARS-CoV-2) More
Total number of polymer chains	2
Total formula weight	34307.15
Authors	Narwal, M.,Murakami, K.S. (deposition date: 2021-01-08, release date: 2021-02-24, Last modification date: 2023-11-15)
Primary citation	Narayanan, A.,Narwal, M.,Majowicz, S.A.,Varricchio, C.,Toner, S.A.,Ballatore, C.,Brancale, A.,Murakami, K.S.,Jose, J. Identification of SARS-CoV-2 inhibitors targeting Mpro and PLpro using in-cell-protease assay. Commun Biol, 5:169-169, 2022 Cited by PubMed: 35217718 DOI: 10.1038/s42003-022-03090-9 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.76 Å)

Structure validation