5JRI
| Structure of an oxidoreductase SeMet-labelled from Synechocystis sp. PCC6803 | 分子名称: | 1,2-ETHANEDIOL, FLAVIN-ADENINE DINUCLEOTIDE, Pyridine nucleotide-disulfide oxidoreductase, ... | 著者 | Buey, R.M, de Pereda, J.M, Balsera, M. | 登録日 | 2016-05-06 | 公開日 | 2017-11-15 | 最終更新日 | 2017-12-13 | 実験手法 | X-RAY DIFFRACTION (1.952 Å) | 主引用文献 | Unprecedented pathway of reducing equivalents in a diflavin-linked disulfide oxidoreductase. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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8DQX
| Open state of RFC:PCNA bound to a 3' ss/dsDNA junction | 分子名称: | DNA (5'-D(*TP*TP*TP*TP*TP*T)-3'), DNA (5'-D(P*TP*CP*CP*GP*AP*GP*CP*GP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*GP*CP*CP*CP*GP*GP*A)-3'), ... | 著者 | Schrecker, M, Hite, R.K. | 登録日 | 2022-07-20 | 公開日 | 2022-08-24 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (2.1 Å) | 主引用文献 | Multistep loading of a DNA sliding clamp onto DNA by replication factor C. Elife, 11, 2022
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5JRW
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8DR6
| Closed state of RFC:PCNA bound to a nicked dsDNA | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA (32-MER), DNA (5'-D(P*CP*CP*CP*CP*CP*CP*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), ... | 著者 | Schrecker, M, Hite, R.K. | 登録日 | 2022-07-20 | 公開日 | 2022-08-24 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (2.39 Å) | 主引用文献 | Multistep loading of a DNA sliding clamp onto DNA by replication factor C. Elife, 11, 2022
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7LD9
| Structure of human GGT1 in complex with ABBA | 分子名称: | (2R)-2-amino-4-boronobutanoic acid, (2S)-2-amino-4-boronobutanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Terzyan, S.S, Hanigan, M. | 登録日 | 2021-01-12 | 公開日 | 2022-02-23 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | 主引用文献 | Design and evaluation of novel analogs of 2-amino-4-boronobutanoic acid (ABBA) as inhibitors of human gamma-glutamyl transpeptidase. Bioorg.Med.Chem., 73, 2022
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5JSR
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5HTY
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1AHP
| OLIGOSACCHARIDE SUBSTRATE BINDING IN ESCHERICHIA COLI MALTODEXTRIN PHSPHORYLASE | 分子名称: | E.COLI MALTODEXTRIN PHOSPHORYLASE, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | O'Reilly, M, Watson, K.A, Schinzel, R, Palm, D, Johnson, L.N. | 登録日 | 1997-04-10 | 公開日 | 1997-10-15 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Oligosaccharide substrate binding in Escherichia coli maltodextrin phosphorylase. Nat.Struct.Biol., 4, 1997
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5U24
| X-ray structure of the WlaRG aminotransferase from campylobacter jejuni, K184A mutant in complex with TDP-Fuc3N | 分子名称: | (2R,3R,4S,5R,6R)-3,5-dihydroxy-4-[(E)-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)amino]-6-methyltetrahydro-2H-pyran-2-yl [(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methyl dihydrogen diphosphate (non-preferred name), 1,2-ETHANEDIOL, CHLORIDE ION, ... | 著者 | Holden, H.M, Thoden, J.B, Dow, G.T, Gilbert, M. | 登録日 | 2016-11-29 | 公開日 | 2017-01-11 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural investigation on WlaRG from Campylobacter jejuni: A sugar aminotransferase. Protein Sci., 26, 2017
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5U7M
| Crystal Structure of HIV-1 BG505 SOSIP.664 Prefusion Env Trimer Bound to Small Molecule HIV-1 Entry Inhibitor BMS-378806 in Complex with Human Antibodies PGT122 and 35O22 at 3.8 Angstrom | 分子名称: | 1-[(2R)-4-(benzenecarbonyl)-2-methylpiperazin-1-yl]-2-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)ethane-1,2-dione, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Pancera, M, Lai, Y.-T, Kwong, P.D. | 登録日 | 2016-12-12 | 公開日 | 2017-08-30 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.025 Å) | 主引用文献 | Crystal structures of trimeric HIV envelope with entry inhibitors BMS-378806 and BMS-626529. Nat. Chem. Biol., 13, 2017
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5EN0
| Crystal Structure of T94I rhodopsin mutant | 分子名称: | ACETATE ION, Guanine nucleotide-binding protein G(t) subunit alpha-3, PALMITIC ACID, ... | 著者 | Singhal, A, Guo, Y, Matkovic, M, Schertler, G, Deupi, X, Yan, E, Standfuss, J. | 登録日 | 2015-11-08 | 公開日 | 2016-08-10 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Structural role of the T94I rhodopsin mutation in congenital stationary night blindness. Embo Rep., 17, 2016
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1AKT
| G61N OXIDIZED FLAVODOXIN MUTANT | 分子名称: | FLAVIN MONONUCLEOTIDE, FLAVODOXIN | 著者 | Mccarthy, A, Walsh, M, Higgins, T. | 登録日 | 1997-05-27 | 公開日 | 1998-05-27 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Modulation of the redox potentials of FMN in Desulfovibrio vulgaris flavodoxin: thermodynamic properties and crystal structures of glycine-61 mutants. Biochemistry, 37, 1998
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1A5F
| FAB FRAGMENT OF A MONOCLONAL ANTI-E-SELECTIN ANTIBODY | 分子名称: | MONOCLONAL ANTI-E-SELECTIN 7A9 ANTIBODY (HEAVY CHAIN), MONOCLONAL ANTI-E-SELECTIN 7A9 ANTIBODY (LIGHT CHAIN) | 著者 | Rodriguez-Romero, A, Almog, O, Tordova, M, Randhawa, Z. | 登録日 | 1998-02-16 | 公開日 | 1999-04-20 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Primary and tertiary structures of the Fab fragment of a monoclonal anti-E-selectin 7A9 antibody that inhibits neutrophil attachment to endothelial cells. J.Biol.Chem., 273, 1998
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5HXV
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1A83
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7RPV
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5AIY
| R6 HUMAN INSULIN HEXAMER (SYMMETRIC), NMR, 'RED' SUBSTATE, AVERAGE STRUCTURE | 分子名称: | PHENOL, PROTEIN (INSULIN) | 著者 | O'Donoghue, S.I, Chang, X, Abseher, R, Nilges, M, Led, J.J. | 登録日 | 1998-12-29 | 公開日 | 2000-02-28 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Unraveling the symmetry ambiguity in a hexamer: calculation of the R6 human insulin structure. J.Biomol.NMR, 16, 2000
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5EQU
| Crystal structure of the epimerase SnoN in complex with Fe3+, alpha ketoglutarate and nogalamycin RO | 分子名称: | 2-OXOGLUTARIC ACID, FE (III) ION, Nogalamycin RO, ... | 著者 | Selvaraj, B, Lindqvist, Y, Siitonen, V, Metsa-Ketela, M, Schneider, G. | 登録日 | 2015-11-13 | 公開日 | 2016-05-11 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Divergent non-heme iron enzymes in the nogalamycin biosynthetic pathway. Proc.Natl.Acad.Sci.USA, 113, 2016
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5ERE
| Extracellular ligand binding receptor from Desulfohalobium retbaense DSM5692 | 分子名称: | 1,2-ETHANEDIOL, 2-OXO-4-METHYLPENTANOIC ACID, 6-AMINOPYRIMIDIN-2(1H)-ONE, ... | 著者 | Cuff, M, Wu, R, Endres, M, Pokkuluri, P.R, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2015-11-14 | 公開日 | 2016-08-10 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A novel extracellular ligand receptor To Be Published
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5H6T
| Crystal structure of Hydrazidase from Microbacterium sp. strain HM58-2 | 分子名称: | Amidase | 著者 | Akiyama, T, Ishii, M, Takuwa, A, Oinuma, K, Sasaki, Y, Takaya, N, Yajima, S. | 登録日 | 2016-11-15 | 公開日 | 2017-03-15 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural basis of the substrate recognition of hydrazidase isolated from Microbacterium sp. strain HM58-2, which catalyzes acylhydrazide compounds as its sole carbon source Biochem. Biophys. Res. Commun., 482, 2017
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5H7L
| Complex of Elongation factor 2-50S ribosomal protein L12 | 分子名称: | 50S ribosomal protein L12, Elongation factor 2, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER | 著者 | Tanzawa, T, Kato, K, Uchiumi, T, Yao, M. | 登録日 | 2016-11-18 | 公開日 | 2018-02-21 | 最終更新日 | 2018-05-02 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | The C-terminal helix of ribosomal P stalk recognizes a hydrophobic groove of elongation factor 2 in a novel fashion Nucleic Acids Res., 46, 2018
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5U21
| X-ray structure of the WlaRF aminotransferase from Campylobacter jejuni, K184A mutant in complex with TDP-Qui3N | 分子名称: | (2R,3R,4S,5S,6R)-3,5-dihydroxy-4-{[(1E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}-6-methyltetrahydro-2H-pyran-2-yl [(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methyl dihydrogen diphosphate, 1,2-ETHANEDIOL, CHLORIDE ION, ... | 著者 | Thoden, J.B, Holden, H.M, Dow, G.T, Gilbert, M. | 登録日 | 2016-11-29 | 公開日 | 2017-01-11 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural investigation on WlaRG from Campylobacter jejuni: A sugar aminotransferase. Protein Sci., 26, 2017
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5EHL
| Rapid Discovery of Pyrido[3,4-d]pyrimidine Inhibitors of Monopolar Spindle kinase 1 (MPS1) Using a Structure-Based Hydridization Approach | 分子名称: | 1-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]urea, Dual specificity protein kinase TTK | 著者 | Innocenti, P, Woodward, H.L, Solanki, S, Naud, N, Westwood, I.M, Cronin, N, Hayes, A, Roberts, J, Henley, A.T, Baker, R, Faisal, A, Mak, G, Box, G, Valenti, M, De Haven Brandon, A, O'Fee, L, Saville, J, Schmitt, J, Burke, R, van Montfort, R.L.M, Raymaud, F.I, Eccles, S.A, Linardopoulos, S, Blagg, J, Hoelder, S. | 登録日 | 2015-10-28 | 公開日 | 2016-11-09 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | 主引用文献 | Rapid Discovery of Pyrido[3,4-d]pyrimidine Inhibitors of Monopolar Spindle kinase 1 (MPS1) Using a Structure-Based Hydridization Approach To Be Published
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155L
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5U3S
| Human PPARdelta ligand-binding domain in complexed with specific agonist 3 | 分子名称: | 6-[2-({[4-(furan-3-yl)benzene-1-carbonyl](propan-2-yl)amino}methyl)phenoxy]hexanoic acid, DI(HYDROXYETHYL)ETHER, POTASSIUM ION, ... | 著者 | Wu, C.-C, Baiga, T.J, Downes, M, La Clair, J.J, Atkins, A.R, Richard, S.B, Stockley-Noel, T.A, Bowman, M.E, Evans, R.M, Noel, J.P. | 登録日 | 2016-12-03 | 公開日 | 2017-03-22 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis for specific ligation of the peroxisome proliferator-activated receptor delta. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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