6O9B
 
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8QWA
 | | Adenylosuccinate Synthetase from H. pylori in complex with PLP and IMP | | 分子名称: | Adenylosuccinate synthetase, GLYCEROL, INOSINIC ACID, ... | | 著者 | Bzowska, A, Narczyk, M, Maksymiuk, W. | | 登録日 | 2023-10-19 | | 公開日 | 2024-09-04 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Vitamin B6 inhibits activity of Helicobacter pylori adenylosuccinate synthetase and growth of reference and clinical, antibiotic-resistant H. pylori strains.
J Enzyme Inhib Med Chem, 39, 2024
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8B5X
 | | Crystal structure of the SUN1-KASH6 9:6 complex | | 分子名称: | CHLORIDE ION, Inositol 1,4,5-triphosphate receptor associated 2, POTASSIUM ION, ... | | 著者 | Erlandsen, B.S, Gurusaran, M, Davies, O.R. | | 登録日 | 2022-09-25 | | 公開日 | 2023-10-04 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | The crystal structure of SUN1-KASH6 reveals an asymmetric LINC complex architecture compatible with nuclear membrane insertion.
Commun Biol, 7, 2024
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8RJJ
 | | HCV E1/E2 homodimer complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Genome polyprotein, ... | | 著者 | Augestad, E.H, Olesen, C.H, Groenberg, C, Soerensen, A, Velazquez-Moctezuma, R, Fanalista, M, Bukh, J, Wang, K, Gourdon, P, Prentoe, J. | | 登録日 | 2023-12-21 | | 公開日 | 2024-09-04 | | 実験手法 | ELECTRON MICROSCOPY (3.55 Å) | | 主引用文献 | The hepatitis C virus envelope protein complex is a dimer of heterodimers
Nature, 2024
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8RK0
 | | HCV E1/E2 homodimer complex, ectodomain | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HCV E1, ... | | 著者 | Augestad, E.H, Olesen, C.H, Groenberg, C, Soerensen, A, Velazquez-Moctezuma, R, Fanalista, M, Bukh, J, Wang, K, Gourdon, P, Prentoe, J. | | 登録日 | 2023-12-22 | | 公開日 | 2024-09-04 | | 実験手法 | ELECTRON MICROSCOPY (3.38 Å) | | 主引用文献 | The hepatitis C virus envelope protein complex is a dimer of heterodimers
Nature, 2024
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8B87
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8B9N
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8TW8
 | | Cryo-EM structure of S. cerevisiae Ctf18-RFC-PCNA complex in Apo state conformation I | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Chromosome transmission fidelity protein 18, MAGNESIUM ION, ... | | 著者 | Yuan, Z, Georgescu, R, O'Donnell, M, Li, H. | | 登録日 | 2023-08-20 | | 公開日 | 2024-09-04 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Cryo-EM reveals that Ctf18-RFC collaborates with PolE to load the PCNA clamp onto a leading strand DNA
To Be Published
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8B9T
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8TW7
 | | Cryo-EM structure of S. cerevisiae Ctf18-RFC-PCNA complex in Apo state conformation I | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Chromosome transmission fidelity protein 18, MAGNESIUM ION, ... | | 著者 | Yuan, Z, Georgescu, R, O'Donnell, M, Li, H. | | 登録日 | 2023-08-20 | | 公開日 | 2024-09-04 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Cryo-EM reveals that Ctf18-RFC collaborates with PolE to load the PCNA clamp onto a leading strand DNA
To Be Published
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8TWB
 | | Cryo-EM structure of S. cerevisiae Ctf18-RFC-PCNA-DNA complex | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Chromosome transmission fidelity protein 18, MAGNESIUM ION, ... | | 著者 | Yuan, Z, Georgescu, R, O'Donnell, M, Li, H. | | 登録日 | 2023-08-20 | | 公開日 | 2024-09-04 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Cryo-EM reveals that Ctf18-RFC collaborates with PolE to load the PCNA clamp onto a leading strand DNA
To Be Published
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8B82
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8B8O
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5SBD
 | | Tubulin-maytansinoid-5b-complex | | 分子名称: | (1S,2R,3S,5S,6S,16E,18E,20R)-11-chloro-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.1~10,14~.0~3,5~]hexacosa-10(26),11,13,16,18,21(25)-hexaen-6-yl acetate, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | | 著者 | Marzullo, P, Boiarska, Z, Perez-Pena, H, Abel, A.-C, Alvarez-Bernad, B, Lucena-Agell, D, Vasile, F, Sironi, M, Steinmetz, M.O, Prota, A.E, Diaz, J.F, Pieraccini, S, Passarella, D. | | 登録日 | 2021-07-20 | | 公開日 | 2021-12-08 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Maytansinol Derivatives: Side Reactions as a Chance for New Tubulin Binders.
Chemistry, 28, 2022
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5SBA
 | | Tubulin-maytansinoid-4b-complex | | 分子名称: | (1S,2R,3S,5S,6S,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.1~10,14~.0~3,5~]hexacosa-10(26),11,13,16,18-pentaen-6-yl acetate, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | | 著者 | Marzullo, P, Boiarska, Z, Perez-Pena, H, Abel, A.-C, Alvarez-Bernad, B, Lucena-Agell, D, Vasile, F, Sironi, M, Steinmetz, M.O, Prota, A.E, Diaz, J.F, Pieraccini, S, Passarella, D. | | 登録日 | 2021-07-20 | | 公開日 | 2021-12-08 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Maytansinol Derivatives: Side Reactions as a Chance for New Tubulin Binders.
Chemistry, 28, 2022
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5HQF
 | | DNA duplex containing a ribonolactone lesion | | 分子名称: | DNA (5'-D(*CP*GP*CP*TP*CP*(RIB)P*CP*AP*CP*GP*C)-3'), DNA (5'-D(*GP*CP*GP*TP*GP*GP*GP*AP*(8OG)P*CP*G)-3') | | 著者 | Zalesak, J, Constant, J.F, Jourdan, M. | | 登録日 | 2016-01-21 | | 公開日 | 2016-09-14 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Nuclear Magnetic Resonance Solution Structure of DNA Featuring Clustered 2'-Deoxyribonolactone and 8-Oxoguanine Lesions.
Biochemistry, 55, 2016
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8BL3
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5SBE
 | | Tubulin-maytansinoid-5c-complex | | 分子名称: | (1S,2R,3S,5S,6S,16E,18E,20R)-11-chloro-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.1~10,14~.0~3,5~]hexacosa-10(26),11,13,16,18,21-hexaen-6-yl hept-6-ynoate, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | | 著者 | Marzullo, P, Boiarska, Z, Perez-Pena, H, Abel, A.-C, Alvarez-Bernad, B, Lucena-Agell, D, Vasile, F, Sironi, M, Steinmetz, M.O, Prota, A.E, Diaz, J.F, Pieraccini, S, Passarella, D. | | 登録日 | 2021-07-20 | | 公開日 | 2021-12-08 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Maytansinol Derivatives: Side Reactions as a Chance for New Tubulin Binders.
Chemistry, 28, 2022
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5SBB
 | | Tubulin-maytansinoid-4c-complex | | 分子名称: | (1R,2R,3S,5S,6S,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.1~10,14~.0~3,5~]hexacosa-10(26),11,13,16,18-pentaen-6-yl heptanoate, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | | 著者 | Marzullo, P, Boiarska, Z, Perez-Pena, H, Abel, A.-C, Alvarez-Bernad, B, Lucena-Agell, D, Vasile, F, Sironi, M, Steinmetz, M.O, Prota, A.E, Diaz, J.F, Pieraccini, S, Passarella, D. | | 登録日 | 2021-07-20 | | 公開日 | 2021-12-08 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Maytansinol Derivatives: Side Reactions as a Chance for New Tubulin Binders.
Chemistry, 28, 2022
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4JJ0
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8BL6
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5SBC
 | | Tubulin-maytansinoid-5a-complex | | 分子名称: | (1S,2R,3S,5S,6S,16E,18E,20R)-11-chloro-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.1~10,14~.0~3,5~]hexacosa-10(26),11,13,16,18,21-hexaen-6-yl phenylacetate, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | | 著者 | Marzullo, P, Boiarska, Z, Perez-Pena, H, Abel, A.-C, Alvarez-Bernad, B, Lucena-Agell, D, Vasile, F, Sironi, M, Steinmetz, M.O, Prota, A.E, Diaz, J.F, Pieraccini, S, Passarella, D. | | 登録日 | 2021-07-20 | | 公開日 | 2021-12-08 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | | 主引用文献 | Maytansinol Derivatives: Side Reactions as a Chance for New Tubulin Binders.
Chemistry, 28, 2022
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8B6N
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5HKF
 | | Crystal structure of Mycobacterium tuberculosis H37Rv orotate phosphoribosyltransferase in complex with 5-phospho-alpha-D-ribosyl 1-diphosphate (PRPP) | | 分子名称: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, Orotate phosphoribosyltransferase | | 著者 | Donini, S, Ferraris, D.M, Bolognesi, G, Rizzi, M. | | 登録日 | 2016-01-14 | | 公開日 | 2017-01-25 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structural investigations on orotate phosphoribosyltransferase from Mycobacterium tuberculosis, a key enzyme of the de novo pyrimidine biosynthesis.
Sci Rep, 7, 2017
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5SB9
 | | Tubulin-maytansinoid-4a-complex | | 分子名称: | (1S,2R,3S,5S,6S,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.1~10,14~.0~3,5~]hexacosa-10(26),11,13,16,18-pentaen-6-yl phenylacetate, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | | 著者 | Marzullo, P, Boiarska, Z, Perez-Pena, H, Abel, A.-C, Alvarez-Bernad, B, Lucena-Agell, D, Vasile, F, Sironi, M, Steinmetz, M.O, Prota, A.E, Diaz, J.F, Pieraccini, S, Passarella, D. | | 登録日 | 2021-07-20 | | 公開日 | 2021-12-08 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Maytansinol Derivatives: Side Reactions as a Chance for New Tubulin Binders.
Chemistry, 28, 2022
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