5IOY
| Structure of Transcriptional Regulatory Repressor Protein - EthR from Mycobacterium Tuberculosis in complex with N-(cyclopentylmethyl)pyrrolidine-1-carboxamide at 1.77A resolution | 分子名称: | N-(cyclopentylmethyl)pyrrolidine-1-carboxamide, SULFATE ION, TetR-family transcriptional regulatory repressor protein | 著者 | Blaszczyk, M, Surade, S, Nikiforov, P.O, Abell, C, Blundell, T.L. | 登録日 | 2016-03-09 | 公開日 | 2017-03-29 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Fragment-Sized EthR Inhibitors Exhibit Exceptionally Strong Ethionamide Boosting Effect in Whole-Cell Mycobacterium tuberculosis Assays. ACS Chem. Biol., 12, 2017
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5F7G
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6XCQ
| Erythromycin esterase EreC, mutant H289N in its closed conformation | 分子名称: | EreC, S-1,2-PROPANEDIOL | 著者 | Zielinski, M, Park, J, Berghuis, A.M. | 登録日 | 2020-06-09 | 公開日 | 2021-02-17 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural and functional insights into esterase-mediated macrolide resistance. Nat Commun, 12, 2021
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5IPA
| Structure of Transcriptional Regulatory Repressor Protein - EthR from Mycobacterium Tuberculosis in complex with (E)-3-(furan-3-yl)-1-(pyrrolidin-1-yl)prop-2-en-1-one at 1.78A resolution | 分子名称: | (2E)-3-(furan-3-yl)-1-(pyrrolidin-1-yl)prop-2-en-1-one, TetR-family transcriptional regulatory repressor protein | 著者 | Blaszczyk, M, Surade, S, Nikiforov, P.O, Abell, C, Blundell, T.L. | 登録日 | 2016-03-09 | 公開日 | 2017-03-29 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Fragment-Sized EthR Inhibitors Exhibit Exceptionally Strong Ethionamide Boosting Effect in Whole-Cell Mycobacterium tuberculosis Assays. ACS Chem. Biol., 12, 2017
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5EWE
| Ternary complex of human DNA polymerase eta inserting rCTP opposite template G | 分子名称: | CALCIUM ION, CYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... | 著者 | Su, Y, Egli, M, Guengerich, F.P. | 登録日 | 2015-11-20 | 公開日 | 2016-01-13 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | Mechanism of Ribonucleotide Incorporation by Human DNA Polymerase eta. J.Biol.Chem., 291, 2016
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5EWP
| ARO (armadillo repeats only protein) from Plasmodium falciparum | 分子名称: | ARO (armadillo repeats only protein) | 著者 | Brown, C, Zhang, K, Emery, J, Prusty, D, Wetzel, J, Heincke, D, Gilberger, T, Junop, M. | 登録日 | 2015-11-20 | 公開日 | 2016-01-27 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | ARO (armadillo repeats only protein) from Plasmodium falciparum To Be Published
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2YYS
| Crystal structure of the proline iminopeptidase-related protein TTHA1809 from Thermus thermophilus HB8 | 分子名称: | GLYCEROL, Proline iminopeptidase-related protein | 著者 | Okai, M, Miyauchi, Y, Ebihara, A, Lee, W.C, Nagata, K, Tanokura, M. | 登録日 | 2007-05-01 | 公開日 | 2008-02-26 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of the proline iminopeptidase-related protein TTHA1809 from Thermus thermophilus HB8 Proteins, 70, 2008
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5I8D
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2Z0L
| Crystal structure of EBV-DNA polymerase accessory protein BMRF1 | 分子名称: | CHLORIDE ION, Early antigen protein D | 著者 | Murayama, K, Kato-Murayama, M, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-05-07 | 公開日 | 2008-05-13 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal structure of Epstein-Barr virus DNA polymerase processivity factor BMRF1 J.Biol.Chem., 284, 2009
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2YQE
| Solution structure of the ARID domain of JARID1D protein | 分子名称: | Jumonji/ARID domain-containing protein 1D | 著者 | Tanabe, W, Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-03-30 | 公開日 | 2008-04-01 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the ARID domain of JARID1D protein To be Published
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5I14
| Truncated and mutated T4 lysozyme | 分子名称: | NICKEL (II) ION, mutated and truncated T4 lysozyme | 著者 | Klima, M, Boura, E. | 登録日 | 2016-02-05 | 公開日 | 2016-02-17 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.745 Å) | 主引用文献 | Metal ions-binding T4 lysozyme as an intramolecular protein purification tag compatible with X-ray crystallography. Protein Sci., 26, 2017
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5F6K
| Crystal structure of the MLL3-Ash2L-RbBP5 complex | 分子名称: | Histone-lysine N-methyltransferase 2C, Retinoblastoma-binding protein 5, S-ADENOSYL-L-HOMOCYSTEINE, ... | 著者 | Li, Y, Lei, M, Chen, Y. | 登録日 | 2015-12-06 | 公開日 | 2016-02-24 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.411 Å) | 主引用文献 | Structural basis for activity regulation of MLL family methyltransferases. Nature, 530, 2016
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2Y7D
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5EZK
| RNA polymerase model placed by Molecular replacement into X-ray diffraction map of DNA-bound RNA Polymerase-Sigma 54 holoenzyme complex. | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Darbari, V.C, Yang, Y, Lu, D, Zhang, N, Glyde, R, Wang, Y, Murakami, K.S, Buck, M, Zhang, X. | 登録日 | 2015-11-26 | 公開日 | 2015-12-16 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (8.5 Å) | 主引用文献 | TRANSCRIPTION. Structures of the RNA polymerase- Sigma 54 reveal new and conserved regulatory strategies. Science, 349, 2015
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5OVL
| crystal structure of MabA bound to NADP+ from M. smegmatis | 分子名称: | 3-oxoacyl-[acyl-carrier-protein] reductase FabG, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Kussau, T, Van Wyk, N, Viljoen, A, Olieric, V, Flipo, M, Kremer, L, Blaise, M. | 登録日 | 2017-08-29 | 公開日 | 2018-02-28 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural rearrangements occurring upon cofactor binding in the Mycobacterium smegmatis beta-ketoacyl-acyl carrier protein reductase MabA. Acta Crystallogr D Struct Biol, 74, 2018
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6XCS
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2Y6C
| The Discovery of MMP7 inhibitors Exploiting a Novel Selectivity Trigger | 分子名称: | CALCIUM ION, MATRILYSIN, N-{[4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]SULFONYL}-L-TRYPTOPHAN, ... | 著者 | Edman, K, Furber, M, Hemsley, P, Johansson, C, Pairaudeau, G, Petersen, J, Stocks, M, Tervo, A, Ward, A, Wells, E, Wissler, L. | 登録日 | 2011-01-20 | 公開日 | 2011-05-04 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The Discovery of Mmp7 Inhibitors Exploiting a Novel Selectivity Trigger. Chemmedchem, 6, 2011
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2Y9M
| Pex4p-Pex22p structure | 分子名称: | 1,2-ETHANEDIOL, PEROXISOME ASSEMBLY PROTEIN 22, UBIQUITIN-CONJUGATING ENZYME E2-21 KDA | 著者 | Williams, C, van den Berg, M, Panjikar, S, Distel, B, Wilmanns, M. | 登録日 | 2011-02-15 | 公開日 | 2011-10-26 | 最終更新日 | 2017-12-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Insights Into Ubiquitin-Conjugating Enzyme/ Co-Activator Interactions from the Structure of the Pex4P:Pex22P Complex. Embo J., 31, 2011
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4I8H
| Bovine trypsin at 0.75 resolution | 分子名称: | BENZAMIDINE, CALCIUM ION, Cationic trypsin, ... | 著者 | Dauter, Z, Liebschner, D, Dauter, M, Brzuszkiewicz, A. | 登録日 | 2012-12-03 | 公開日 | 2012-12-19 | 最終更新日 | 2013-09-18 | 実験手法 | X-RAY DIFFRACTION (0.75 Å) | 主引用文献 | On the reproducibility of protein crystal structures: five atomic resolution structures of trypsin. Acta Crystallogr.,Sect.D, 69, 2013
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5IG1
| Crystal structure of S. rosetta CaMKII kinase domain | 分子名称: | CAMK/CAMK2 protein kinase, PHOSPHATE ION | 著者 | Bhattacharyya, M, Gee, C.L, Barros, T, Kuriyan, J. | 登録日 | 2016-02-26 | 公開日 | 2016-03-23 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Molecular mechanism of activation-triggered subunit exchange in Ca(2+)/calmodulin-dependent protein kinase II. Elife, 5, 2016
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1ICY
| [ALA31,PRO32]-PNPY BOUND TO DPC MICELLES | 分子名称: | NEUROPEPTIDE Y | 著者 | Bader, R, Rytz, G, Lerch, M, Beck-Sickinger, A.G, Zerbe, O. | 登録日 | 2001-04-02 | 公開日 | 2002-05-08 | 最終更新日 | 2021-10-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Key motif to gain selectivity at the neuropeptide Y5-receptor: structure and dynamics of micelle-bound [Ala31, Pro32]-NPY. Biochemistry, 41, 2002
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5F38
| X-ray crystal structure of a thiolase from Escherichia coli at 1.8 A resolution | 分子名称: | 1,2-ETHANEDIOL, Acetyl-CoA acetyltransferase, COENZYME A, ... | 著者 | Ithayaraja, M, Neelanjana, J, Wierenga, R, Savithri, H.S, Murthy, M.R.N. | 登録日 | 2015-12-02 | 公開日 | 2016-07-13 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of a thiolase from Escherichia coli at 1.8 angstrom resolution. Acta Crystallogr.,Sect.F, 72, 2016
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2YLY
| Sulfonamides as selective Estrogen Receptor beta Agonists. | 分子名称: | ESTROGEN RECEPTOR BETA, N-cyclopropyl-4-oxidanyl-N-[(2R)-2-oxidanyl-2-phenyl-propyl]benzenesulfonamide, SULFATE ION | 著者 | Roberts, L.R, Armour, D, Barker, C, Bazin, R, Bess, K, Brown, A, Favor, D, Ellis, D, MacKenny, M, Pullen, N, Stennett, A, Strand, L, Styles, M, Phillips, C. | 登録日 | 2011-06-06 | 公開日 | 2012-06-13 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Sulfonamides as Selective Oestrogen Receptor Beta Agonists. Bioorg.Med.Chem.Lett., 21, 2011
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5OXT
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7RLR
| Crystal Structure of K83A Mutant of Class D beta-lactamase from Clostridium difficile 630 | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Beta-lactamase, ... | 著者 | Minasov, G, Shuvalova, L, Dubrovska, I, Rosas-Lemus, M, Jedrzejczak, R, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2021-07-26 | 公開日 | 2021-08-11 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Crystal Structure of K83A Mutant of Class D beta-lactamase from Clostridium difficile 630 To Be Published
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