7OS7
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![BU of 7os7 by Molmil](/molmil-images/mine/7os7) | Circular permutant of ribosomal protein S6, swap helix 2, L75A, A92K mutant | 分子名称: | 30S ribosomal protein S6,30S ribosomal protein S6 | 著者 | Wang, H, Logan, D.T, Oliveberg, M. | 登録日 | 2021-06-08 | 公開日 | 2022-06-22 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Circular permutant of ribosomal protein S6, swap helix 2, L75A, A92K mutant To Be Published
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152L
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2OPT
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1L6R
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![BU of 1l6r by Molmil](/molmil-images/mine/1l6r) | Crystal Structure of Thermoplasma acidophilum 0175 (APC0014) | 分子名称: | CALCIUM ION, FORMIC ACID, HYPOTHETICAL PROTEIN TA0175 | 著者 | Kim, Y, Joachimiak, A, Edwards, A.M, Xu, X, Pennycooke, M, Gu, J, Cheung, F, Christendat, D, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2002-03-13 | 公開日 | 2003-01-21 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structure- and function-based characterization of a new phosphoglycolate phosphatase from Thermoplasma acidophilum. J.Biol.Chem., 279, 2004
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1UWR
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![BU of 1uwr by Molmil](/molmil-images/mine/1uwr) | Structure of beta-glycosidase from Sulfolobus solfataricus in complex with 2-deoxy-2-fluoro-galactose | 分子名称: | 2-deoxy-2-fluoro-alpha-D-galactopyranose, ACETATE ION, BETA-GALACTOSIDASE | 著者 | Gloster, T.M, Roberts, S, Ducros, V.M.-A, Perugino, G, Rossi, M, Hoos, R, Moracci, M, Vasella, A, Davies, G.J. | 登録日 | 2004-02-11 | 公開日 | 2004-05-20 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Structural Studies of the Beta-Glycosidase from Sulfolobus Solfataricus in Complex with Covalently and Noncovalently Bound Inhibitors. Biochemistry, 43, 2004
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7OVO
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![BU of 7ovo by Molmil](/molmil-images/mine/7ovo) | Heterodimeric murine tRNA-guanine transglycosylase in complex with queuine | 分子名称: | 2-amino-5-({[(1S,4S,5R)-4,5-dihydroxycyclopent-2-en-1-yl]amino}methyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one, DIMETHYL SULFOXIDE, Queuine tRNA-ribosyltransferase accessory subunit 2, ... | 著者 | Sebastiani, M, Heine, A, Reuter, K. | 登録日 | 2021-06-15 | 公開日 | 2022-06-22 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural and Biochemical Investigation of the Heterodimeric Murine tRNA-Guanine Transglycosylase. Acs Chem.Biol., 17, 2022
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1UK2
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![BU of 1uk2 by Molmil](/molmil-images/mine/1uk2) | Crystal structure of SARS Coronavirus Main Proteinase (3CLpro) At pH8.0 | 分子名称: | 3C-LIKE PROTEINASE | 著者 | Yang, H, Yang, M, Liu, Y, Bartlam, M, Ding, Y, Lou, Z, Sun, L, Zhou, Z, Ye, S, Anand, K, Pang, H, Gao, G.F, Hilgenfeld, R, Rao, Z. | 登録日 | 2003-08-14 | 公開日 | 2003-11-18 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor Proc.Natl.Acad.Sci.USA, 100, 2003
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2O0R
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![BU of 2o0r by Molmil](/molmil-images/mine/2o0r) | The three-dimensional structure of N-Succinyldiaminopimelate aminotransferase from Mycobacterium tuberculosis | 分子名称: | CHLORIDE ION, GLYCEROL, Rv0858c (N-Succinyldiaminopimelate aminotransferase), ... | 著者 | Weyand, S, Kefala, G, Weiss, M.S, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2006-11-28 | 公開日 | 2007-02-27 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The Three-dimensional Structure of N-Succinyldiaminopimelate Aminotransferase from Mycobacterium tuberculosis J.Mol.Biol., 367, 2007
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6HVR
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![BU of 6hvr by Molmil](/molmil-images/mine/6hvr) | Yeast 20S proteasome with human beta2i (1-53) in complex with 16 | 分子名称: | (2~{S})-~{N}-[(2~{S},3~{R})-1-[[(2~{S})-1-[4-(aminomethyl)phenyl]-4-methylsulfonyl-butan-2-yl]amino]-3-oxidanyl-1-oxidanylidene-butan-2-yl]-2-[[(2~{R})-2-azido-3-phenyl-propanoyl]amino]-4-methyl-pentanamide, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Huber, E.M, Groll, M. | 登録日 | 2018-10-11 | 公開日 | 2019-01-30 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits. J.Med.Chem., 62, 2019
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6QID
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![BU of 6qid by Molmil](/molmil-images/mine/6qid) | Crystal structure of DEAH-box ATPase Prp43-S387A | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ... | 著者 | Hamann, F, Ficner, R, Enders, M. | 登録日 | 2019-01-18 | 公開日 | 2019-03-06 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.204 Å) | 主引用文献 | Structural basis for RNA translocation by DEAH-box ATPases. Nucleic Acids Res., 47, 2019
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6NYS
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1UK3
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![BU of 1uk3 by Molmil](/molmil-images/mine/1uk3) | Crystal structure of SARS Coronavirus Main Proteinase (3CLpro) At pH7.6 | 分子名称: | 3C-like proteinase | 著者 | Yang, H, Yang, M, Liu, Y, Bartlam, M, Ding, Y, Lou, Z, Sun, L, Zhou, Z, Ye, S, Anand, K, Pang, H, Gao, G.F, Hilgenfeld, R, Rao, Z. | 登録日 | 2003-08-14 | 公開日 | 2003-11-18 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor Proc.Natl.Acad.Sci.USA, 100, 2003
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6QJH
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![BU of 6qjh by Molmil](/molmil-images/mine/6qjh) | Cryo-EM structure of heparin-induced 2N4R tau snake filaments | 分子名称: | Microtubule-associated protein tau | 著者 | Zhang, W, Falcon, B, Murzin, A.G, Fan, J, Crowther, R.A, Goedert, M, Scheres, S.H.W. | 登録日 | 2019-01-24 | 公開日 | 2019-02-20 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases. Elife, 8, 2019
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6HSH
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![BU of 6hsh by Molmil](/molmil-images/mine/6hsh) | Crystal structure of Schistosoma mansoni HDAC8 complexed with Quisinostat | 分子名称: | 2-[4-[[(1-methylindol-3-yl)methylamino]methyl]piperidin-1-yl]-~{N}-oxidanyl-pyrimidine-5-carboxamide, DIMETHYLFORMAMIDE, GLYCEROL, ... | 著者 | Shaik, T.B, Marek, M, Romier, C. | 登録日 | 2018-10-01 | 公開日 | 2018-10-31 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.545 Å) | 主引用文献 | Characterization of Histone Deacetylase 8 (HDAC8) Selective Inhibition Reveals Specific Active Site Structural and Functional Determinants. J. Med. Chem., 61, 2018
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6HWC
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![BU of 6hwc by Molmil](/molmil-images/mine/6hwc) | Yeast 20S proteasome beta2-G45A mutant | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Huber, E.M, Groll, M. | 登録日 | 2018-10-11 | 公開日 | 2019-01-30 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits. J.Med.Chem., 62, 2019
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6QJM
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![BU of 6qjm by Molmil](/molmil-images/mine/6qjm) | Cryo-EM structure of heparin-induced 2N4R tau twister filaments | 分子名称: | Microtubule-associated protein tau | 著者 | Zhang, W, Falcon, B, Murzin, A.G, Fan, J, Crowther, R.A, Goedert, M, Scheres, S.H.W. | 登録日 | 2019-01-24 | 公開日 | 2019-02-27 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases. Elife, 8, 2019
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6FU1
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![BU of 6fu1 by Molmil](/molmil-images/mine/6fu1) | Crystal structure of Schistosoma mansoni HDAC8 complexed with a n-alkyl hydroxamate | 分子名称: | GLYCEROL, Histone deacetylase, POTASSIUM ION, ... | 著者 | Marek, M, Shaik, T.B, Romier, C. | 登録日 | 2018-02-26 | 公開日 | 2019-03-13 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.548 Å) | 主引用文献 | A Novel Class of Schistosoma mansoni Histone Deacetylase 8 (HDAC8) Inhibitors Identified by Structure-Based Virtual Screening and In Vitro Testing. Molecules, 23, 2018
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7ORP
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![BU of 7orp by Molmil](/molmil-images/mine/7orp) | crystal structure of human carbonic anhydrase II in complex with 4-((2-hydroxy-3-((3,4,5-trimethoxyphenyl)tellanyl)propyl)selanyl)benzenesulfonamide | 分子名称: | 4-[(2R)-2-oxidanyl-3-(3,4,5-trimethylphenyl)tellanyl-propyl]selanylbenzenesulfonamide, 4-[(2S)-2-oxidanyl-3-(3,4,5-trimethoxyphenyl)tellanyl-propyl]selanylbenzenesulfonamide, Carbonic anhydrase 2, ... | 著者 | Angeli, A, Ferraroni, M. | 登録日 | 2021-06-06 | 公開日 | 2022-06-22 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | 主引用文献 | Chalcogenides-incorporating carbonic anhydrase inhibitors concomitantly reverted oxaliplatin-induced neuropathy and enhanced antiproliferative action. Eur.J.Med.Chem., 225, 2021
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6QJQ
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![BU of 6qjq by Molmil](/molmil-images/mine/6qjq) | Cryo-EM structure of heparin-induced 2N3R tau filaments | 分子名称: | Microtubule-associated protein tau | 著者 | Zhang, W, Falcon, B, Murzin, A.G, Fan, J, Crowther, R.A, Goedert, M, Scheres, S.H.W. | 登録日 | 2019-01-24 | 公開日 | 2019-02-20 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases. Elife, 8, 2019
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3NHP
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1ZO4
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![BU of 1zo4 by Molmil](/molmil-images/mine/1zo4) | Crystal Structure Of A328S Mutant Of The Heme Domain Of P450BM-3 | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Bifunctional P-450:NADPH-P450 reductase, GLYCEROL, ... | 著者 | Hegda, A, Chen, B, Haines, D.C, Bondlela, M, Mullin, D, Graham, S.E, Tomchick, D.R, Machius, M, Peterson, J.A. | 登録日 | 2005-05-12 | 公開日 | 2006-08-01 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | 主引用文献 | A single active-site mutation of P450BM-3 dramatically enhances substrate binding and rate of product formation. Biochemistry, 50, 2011
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1UK4
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![BU of 1uk4 by Molmil](/molmil-images/mine/1uk4) | Crystal structure of SARS Coronavirus Main Proteinase (3CLpro) Complexed With An Inhibitor | 分子名称: | 3C-like proteinase nsp5, 5-mer peptide of inhibitor | 著者 | Yang, H, Yang, M, Liu, Y, Bartlam, M, Ding, Y, Lou, Z, Sun, L, Zhou, Z, Ye, S, Anand, K, Pang, H, Gao, G.F, Hilgenfeld, R, Rao, Z. | 登録日 | 2003-08-14 | 公開日 | 2003-11-18 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor Proc.Natl.Acad.Sci.USA, 100, 2003
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6QGR
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![BU of 6qgr by Molmil](/molmil-images/mine/6qgr) | The F420-reducing [NiFe] hydrogenase complex from Methanosarcina barkeri at the Nia-S state | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, (R,R)-2,3-BUTANEDIOL, Coenzyme F420 hydrogenase subunit alpha, ... | 著者 | Ilina, Y, Lorent, C, Katz, S, Jeoung, J.H, Shima, S, Horch, M, Zebger, I, Dobbek, H. | 登録日 | 2019-01-12 | 公開日 | 2019-10-23 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.839 Å) | 主引用文献 | X-ray Crystallography and Vibrational Spectroscopy Reveal the Key Determinants of Biocatalytic Dihydrogen Cycling by [NiFe] Hydrogenases. Angew.Chem.Int.Ed.Engl., 58, 2019
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7OR1
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![BU of 7or1 by Molmil](/molmil-images/mine/7or1) | Cryo-EM structure of the human TRPA1 ion channel in complex with the antagonist 3-60, conformation 1 | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Grieben, M, Pike, A.C.W, Saward, B.G, Wang, D, Mukhopadhyay, S.M.M, Moreira, T, Chalk, R, MacLean, E.M, Marsden, B.D, Burgess-Brown, N.A, Bountra, C, Schofield, C.J, Carpenter, E.P, Structural Genomics Consortium (SGC) | 登録日 | 2021-06-04 | 公開日 | 2022-06-22 | 実験手法 | ELECTRON MICROSCOPY (2.64 Å) | 主引用文献 | Cryo-EM structure of the human TRPA1 ion channel in complex with the antagonist 3-60 TO BE PUBLISHED
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6HTR
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![BU of 6htr by Molmil](/molmil-images/mine/6htr) | Yeast 20S proteasome with human beta2c (S171G) in complex with 13 | 分子名称: | (2~{S})-~{N}-[(2~{S})-1-[[(2~{S})-1-[4-(aminomethyl)phenyl]-4-methylsulfonyl-butan-2-yl]amino]-3-oxidanyl-1-oxidanylidene-propan-2-yl]-2-[[(2~{S})-2-azido-3-phenyl-propanoyl]amino]-4-methyl-pentanamide, MAGNESIUM ION, PROTEASOME SUBUNIT ALPHA TYPE-1, ... | 著者 | Huber, E.M, Groll, M. | 登録日 | 2018-10-04 | 公開日 | 2019-01-30 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits. J.Med.Chem., 62, 2019
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