6WAP
| Atomic-Resolution Structure of HIV-1 Capsid Tubes by Magic Angle Spinning NMR | 分子名称: | HIV-1 capsid protein | 著者 | Lu, M, Russell, R.W, Bryer, A, Quinn, C.M, Hou, G, Zhang, H, Schwieters, C.D, Perilla, J.R, Gronenborn, A.M, Polenova, T. | 登録日 | 2020-03-25 | 公開日 | 2020-09-02 | 最終更新日 | 2024-05-15 | 実験手法 | SOLID-STATE NMR | 主引用文献 | Atomic-resolution structure of HIV-1 capsid tubes by magic-angle spinning NMR. Nat.Struct.Mol.Biol., 27, 2020
|
|
6GAQ
| Crystal structure of oxidised Flavodoxin 2 from Bacillus cereus | 分子名称: | CALCIUM ION, FLAVIN MONONUCLEOTIDE, Flavodoxin, ... | 著者 | Lofstad, M, Gudim, I, Hersleth, H.-P. | 登録日 | 2018-04-12 | 公開日 | 2018-09-05 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The Characterization of Different Flavodoxin Reductase-Flavodoxin (FNR-Fld) Interactions Reveals an Efficient FNR-Fld Redox Pair and Identifies a Novel FNR Subclass. Biochemistry, 57, 2018
|
|
6Q62
| |
6WCF
| Crystal Structure of ADP ribose phosphatase of NSP3 from SARS-CoV-2 in complex with MES | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Non-structural protein 3 | 著者 | Michalska, K, Kim, Y, Jedrzejczak, R, Maltseva, N, Endres, M, Mesecar, A, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2020-03-30 | 公開日 | 2020-04-15 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.065 Å) | 主引用文献 | Crystal structures of SARS-CoV-2 ADP-ribose phosphatase: from the apo form to ligand complexes. Iucrj, 7, 2020
|
|
7PBK
| Vibriophage phiVC8 family A DNA polymerase (DpoZ), two conformations: thumb-exo open and thumb-exo closed | 分子名称: | DNA polymerase I | 著者 | Czernecki, D, Hu, H, Romoli, F, Delarue, M. | 登録日 | 2021-08-02 | 公開日 | 2021-11-17 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural dynamics and determinants of 2-aminoadenine specificity in DNA polymerase DpoZ of vibriophage phi VC8. Nucleic Acids Res., 49, 2021
|
|
3MRE
| Crystal Structure of MHC class I HLA-A2 molecule complexed with EBV bmlf1-280-288 nonapeptide | 分子名称: | 9-meric peptide from mRNA export factor EB2, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | 著者 | Gras, S, Echasserieau, K, Saulquin, X, Bonneville, M, Housset, D. | 登録日 | 2010-04-29 | 公開日 | 2011-05-25 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Analysis of Relationships between Peptide/MHC Structural Features and Naive T Cell Frequency in Humans. J.Immunol., 193, 2014
|
|
6NI9
| |
1XHX
| Phi29 DNA Polymerase, orthorhombic crystal form | 分子名称: | DNA polymerase, MAGNESIUM ION, SULFATE ION | 著者 | Kamtekar, S, Berman, A.J, Wang, J, Lazaro, J.M, de Vega, M, Blanco, L, Salas, M, Steitz, T.A. | 登録日 | 2004-09-21 | 公開日 | 2004-12-07 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Insights into Strand Displacement and Processivity from the Crystal Structure of the Protein-Primed DNA Polymerase of Bacteriophage phi29 Mol.Cell, 16, 2004
|
|
8A11
| Cryo-EM structure of the Human SHMT1-RNA complex | 分子名称: | PYRIDOXAL-5'-PHOSPHATE, Serine hydroxymethyltransferase, cytosolic | 著者 | Spizzichino, S, Marabelli, C, Bharadwaj, A, Jakobi, A.J, Chaves-Sanjuan, A, Giardina, G, Bolognesi, M, Cutruzzola, F. | 登録日 | 2022-05-30 | 公開日 | 2023-06-14 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.52 Å) | 主引用文献 | Structure-based mechanism of riboregulation of the metabolic enzyme SHMT1. Mol.Cell, 2024
|
|
6VJN
| Structure of NHP D11A.B5Fab in complex with 16055 V2b peptide | 分子名称: | D11A.B5 Fab Heavy chain, D11A.B5 Fab Light chain, SODIUM ION, ... | 著者 | Singh, S, Liban, T.J, Pancera, M. | 登録日 | 2020-01-16 | 公開日 | 2021-01-20 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structurally related but genetically unrelated antibody lineages converge on an immunodominant HIV-1 Env neutralizing determinant following trimer immunization. Plos Pathog., 17, 2021
|
|
1T48
| Allosteric Inhibition of Protein Tyrosine Phosphatase 1B | 分子名称: | 3-(3,5-DIBROMO-4-HYDROXY-BENZOYL)-2-ETHYL-BENZOFURAN-6-SULFONIC ACID DIMETHYLAMIDE, Protein-tyrosine phosphatase, non-receptor type 1 | 著者 | Wiesmann, C, Barr, K.J, Kung, J, Zhu, J, Shen, W, Fahr, B.J, Zhong, M, Erlanson, D.A, Taylor, L, Randal, M, McDowell, R.S, Hansen, S.K. | 登録日 | 2004-04-28 | 公開日 | 2004-07-20 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Allosteric inhibition of protein tyrosine phosphatase 1B Nat.Struct.Mol.Biol., 11, 2004
|
|
6Q3W
| Structure of human galactokinase 1 bound with Ethyl 1-(2-pyrazinyl)-4-piperidinecarboxylate | 分子名称: | 2-(1,3-benzoxazol-2-ylamino)spiro[1,6,7,8-tetrahydroquinazoline-4,1'-cyclohexane]-5-one, Galactokinase, beta-D-galactopyranose, ... | 著者 | Mackinnon, S.R, Bezerra, G.A, Zhang, M, Foster, W, Krojer, T, Brandao-Neto, J, Douangamath, A, Arrowsmith, C, Edwards, A, Bountra, C, Brennan, P, Lai, K, Yue, W.W. | 登録日 | 2018-12-04 | 公開日 | 2019-01-23 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.962 Å) | 主引用文献 | Structure of human galactokinase 1 bound with Ethyl 1-(2-pyrazinyl)-4-piperidinecarboxylate To Be Published
|
|
6NLJ
| 1.65 A resolution structure of Apo BfrB from Pseudomonas aeruginosa in complex with a protein-protein interaction inhibitor (analog 12) | 分子名称: | 4-{[(3-hydroxyphenyl)methyl]amino}-1H-isoindole-1,3(2H)-dione, Ferroxidase, POTASSIUM ION | 著者 | Lovell, S, Punchi-Hewage, A, Battaile, K.P, Yao, H, Nammalwar, B, Gnanasekaran, K.K, Bunce, R.A, Reitz, A.B, Rivera, M. | 登録日 | 2019-01-08 | 公開日 | 2019-05-08 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Small Molecule Inhibitors of the BfrB-Bfd Interaction Decrease Pseudomonas aeruginosa Fitness and Potentiate Fluoroquinolone Activity. J.Am.Chem.Soc., 141, 2019
|
|
6Q4S
| Crystal structure of a-eudesmol synthase | 分子名称: | CHLORIDE ION, Pentalenene synthase | 著者 | Correia Cordeiro, R.S, Hakansson, M, Logan, D.T, Kourist, R. | 登録日 | 2018-12-06 | 公開日 | 2018-12-19 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Discovery of three novel sesquiterpene synthases from Streptomyces chartreusis NRRL 3882 and crystal structure of an alpha-eudesmol synthase. J.Biotechnol., 297, 2019
|
|
5AYN
| Crystal structure of a bacterial homologue of iron transporter ferroportin in outward-facing state | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, POTASSIUM ION, Solute carrier family 39 (Iron-regulated transporter) | 著者 | Taniguchi, R, Kato, H.E, Font, J, Deshpande, C.N, Ishitani, R, Jormakka, M, Nureki, O. | 登録日 | 2015-08-25 | 公開日 | 2015-11-04 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.202 Å) | 主引用文献 | Outward- and inward-facing structures of a putative bacterial transition-metal transporter with homology to ferroportin Nat Commun, 6, 2015
|
|
6QA3
| ERK2 mini-fragment binding | 分子名称: | Mitogen-activated protein kinase 1, PYRAZOLE, SULFATE ION | 著者 | O'Reilly, M, Cleasby, A, Davies, T.G, Hall, R, Ludlow, F, Murray, C.W, Tisi, D, Jhoti, H. | 登録日 | 2018-12-18 | 公開日 | 2019-06-26 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | Crystallographic screening using ultra-low-molecular-weight ligands to guide drug design. Drug Discov Today, 24, 2019
|
|
2O0T
| |
1T6C
| Structural characterization of the Ppx/GppA protein family: crystal structure of the Aquifex aeolicus family member | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, CHLORIDE ION, ... | 著者 | Kristensen, O, Laurberg, M, Liljas, A, Kastrup, J.S, Gajhede, M. | 登録日 | 2004-05-06 | 公開日 | 2004-08-03 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | 主引用文献 | Structural characterization of the stringent response related exopolyphosphatase/guanosine pentaphosphate phosphohydrolase protein family Biochemistry, 43, 2004
|
|
6I95
| |
6Q84
| Crystal structure of RanGTP-Pdr6-eIF5A export complex | 分子名称: | Eukaryotic translation initiation factor 5A-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Aksu, M, Trakhanov, S, Vera-Rodriguez, A, Gorlich, D. | 登録日 | 2018-12-14 | 公開日 | 2019-05-01 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Structural basis for the nuclear import and export functions of the biportin Pdr6/Kap122. J.Cell Biol., 218, 2019
|
|
7P0L
| |
6G5T
| Myoglobin H64V/V68A in the resting state, 1.5 Angstrom resolution | 分子名称: | 1,2-ETHANEDIOL, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Tinzl, M, Hayashi, T, Mori, T, Hilvert, D. | 登録日 | 2018-03-30 | 公開日 | 2018-08-22 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Capture and characterization of a reactive haem-carbenoid complex in an artificial metalloenzyme Nat Catal, 1, 2018
|
|
6Q93
| MgADP-bound Fe protein of Vanadium nitrogenase from Azotobacter vinelandii | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, IRON/SULFUR CLUSTER, MAGNESIUM ION, ... | 著者 | Rohde, M, Gerhardt, S, Einsle, O. | 登録日 | 2018-12-17 | 公開日 | 2019-02-27 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of VnfH, the iron protein component of vanadium nitrogenase. J. Biol. Inorg. Chem., 23, 2018
|
|
5K06
| Recombinant bovine beta-lactoglobulin with uncleaved N-terminal methionine (rBlgB) | 分子名称: | Beta-lactoglobulin, GLYCEROL, MYRISTIC ACID, ... | 著者 | Loch, J.I, Bonarek, P, Tworzydlo, M, Polit, A, Hawro, B, Lach, A, Ludwin, E, Lewinski, K. | 登録日 | 2016-05-17 | 公開日 | 2016-07-20 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Engineered beta-Lactoglobulin Produced in E. coli: Purification, Biophysical and Structural Characterisation. Mol Biotechnol., 58, 2016
|
|
6NU1
| Crystal Structure of Human PKM2 in Complex with L-cysteine | 分子名称: | 1,6-di-O-phosphono-beta-D-fructofuranose, CYSTEINE, MAGNESIUM ION, ... | 著者 | Srivastava, D, Nandi, S, Dey, M. | 登録日 | 2019-01-30 | 公開日 | 2019-08-21 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Mechanistic and Structural Insights into Cysteine-Mediated Inhibition of Pyruvate Kinase Muscle Isoform 2. Biochemistry, 58, 2019
|
|