4HPJ
 
 | | Crystal structure of Tryptophan Synthase at 1.45 A resolution in complex with 2-aminophenol quinonoid in the beta site and the F9 inhibitor in the alpha site | | 分子名称: | (2E)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)imino]-3-[(2-hydroxyphenyl)amino]propanoic acid, 2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATE, BICINE, ... | | 著者 | Hilario, E, Niks, D, Dunn, M.F, Mueller, L.J, Fan, L. | | 登録日 | 2012-10-23 | | 公開日 | 2013-12-25 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Allostery and substrate channeling in the tryptophan synthase bienzyme complex: evidence for two subunit conformations and four quaternary states.
Biochemistry, 52, 2013
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2CLF
 | | Tryptophan Synthase in complex with N-(4'-trifluoromethoxybenzoyl)-2- amino-1-ethylphosphate (F6) - highF6 complex | | 分子名称: | 2-{[4-(TRIFLUOROMETHOXY)BENZOYL]AMINO}ETHYL DIHYDROGEN PHOSPHATE, PYRIDOXAL-5'-PHOSPHATE, SODIUM ION, ... | | 著者 | Ngo, H, Harris, R, Kimmich, N, Casino, P, Niks, D, Blumenstein, L, Barends, T.R, Kulik, V, Weyand, M, Schlichting, I, Dunn, M.F. | | 登録日 | 2006-04-27 | | 公開日 | 2007-06-26 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Synthesis and Characterization of Allosteric Probes of Substrate Channeling in the Tryptophan Synthase Bienzyme Complex.
Biochemistry, 46, 2007
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4I9T
 | | Structure of the H258Y mutant of the phosphatidylinositol-specific phospholipase C from Staphylococcus aureus | | 分子名称: | 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE, 1-phosphatidylinositol phosphodiesterase, SULFATE ION, ... | | 著者 | Goldstein, R.I, Cheng, J, Stec, B, Gershenson, A, Roberts, M.F. | | 登録日 | 2012-12-05 | | 公開日 | 2013-04-10 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The cation-pi box is a specific phosphatidylcholine membrane targeting motif.
J.Biol.Chem., 288, 2013
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4I6J
 | | A ubiquitin ligase-substrate complex | | 分子名称: | Cryptochrome-2, F-box/LRR-repeat protein 3, S-phase kinase-associated protein 1 | | 著者 | Xing, W, Busino, L, Hinds, T.R, Marionni, S.T, Saifee, N.H, Bush, M.F, Pagano, M, Zheng, N. | | 登録日 | 2012-11-29 | | 公開日 | 2013-03-13 | | 最終更新日 | 2013-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | SCFFBXL3 ubiquitin ligase targets cryptochromes at their cofactor pocket.
Nature, 496, 2013
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1AI8
 | | HUMAN ALPHA-THROMBIN TERNARY COMPLEX WITH THE EXOSITE INHIBITOR HIRUGEN AND ACTIVE SITE INHIBITOR PHCH2OCO-D-DPA-PRO-BOROMPG | | 分子名称: | ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), HIRUDIN IIIB, ... | | 著者 | Skordalakes, E, Dodson, G, Elgendy, S, Goodwin, C.A, Green, D, Tyrrel, R, Scully, M.F, Freyssinet, J, Kakkar, V.V, Deadman, J. | | 登録日 | 1997-05-01 | | 公開日 | 1997-10-15 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | The refined 1.9-A X-ray crystal structure of D-Phe-Pro-Arg chloromethylketone-inhibited human alpha-thrombin: structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationships.
Protein Sci., 1, 1992
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3F2K
 | | Structure of the transposase domain of human Histone-lysine N-methyltransferase SETMAR | | 分子名称: | Histone-lysine N-methyltransferase SETMAR, LYFA Peptide, MAGNESIUM ION | | 著者 | Amaya, M.F, Dombrovski, L, Ni, S, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Botchkarev, A, Min, J, Plotnikov, A.N, Wu, H, Structural Genomics Consortium (SGC) | | 登録日 | 2008-10-29 | | 公開日 | 2008-11-25 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | The Crystal Structure of Transposase Domain of Human
Histone-lysine N-methyltransferase SETMAR.
To be Published
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3F2U
 | | Crystal structure of human chromobox homolog 1 (CBX1) | | 分子名称: | Chromobox protein homolog 1 | | 著者 | Amaya, M.F, Ravichandran, M, Tempel, W, Wernimont, A.K, Loppnau, P, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Botchkarev, A, Min, J, Ouyang, H, Structural Genomics Consortium (SGC) | | 登録日 | 2008-10-30 | | 公開日 | 2008-11-25 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of the complex of human chromobox homolog 1 (CBX1)
To be Published
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3FI8
 | | Crystal structure of choline kinase from Plasmodium Falciparum, PF14_0020 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Choline kinase, MAGNESIUM ION, ... | | 著者 | Wernimont, A.K, Pizarro, J.C, Artz, J.D, Amaya, M.F, Xiao, T, Lew, J, Wasney, G, Senesterra, G, Kozieradzki, I, Cossar, D, Vedadi, M, Schapira, M, Bochkarev, A, Arrowsmith, C.H, Bountra, C, Weigelt, J, Edwards, A.M, Hui, R, Hills, T, Structural Genomics Consortium (SGC) | | 登録日 | 2008-12-11 | | 公開日 | 2009-02-10 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of choline kinase from Plasmodium Falciparum, PF14_0020
TO BE PUBLISHED
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3FDR
 | | Crystal structure of TDRD2 | | 分子名称: | Tudor and KH domain-containing protein | | 著者 | Amaya, M.F, Adams, M.A, Guo, Y, Li, Y, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2008-11-26 | | 公開日 | 2009-01-06 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Mouse Piwi interactome identifies binding mechanism of Tdrkh Tudor domain to arginine methylated Miwi
Proc.Natl.Acad.Sci.USA, 106, 2009
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3FEO
 | | The crystal structure of MBTD1 | | 分子名称: | MBT domain-containing protein 1 | | 著者 | Amaya, M.F, Eryilmaz, J, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2008-11-30 | | 公開日 | 2009-01-06 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural studies of a four-MBT repeat protein MBTD1.
Plos One, 4, 2009
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1BFM
 | | HISTONE B FROM METHANOTHERMUS FERVIDUS | | 分子名称: | HISTONE B | | 著者 | Starich, M.R, Sandman, K, Reeve, J.N, Summers, M.F. | | 登録日 | 1995-09-28 | | 公開日 | 1996-01-29 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structure of HMfB from the hyperthermophile, Methanothermus fervidus, confirms that this archaeal protein is a histone.
J.Mol.Biol., 255, 1996
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3HHT
 | | A mutant of the nitrile hydratase from Geobacillus pallidus having enhanced thermostability | | 分子名称: | CHLORIDE ION, COBALT (III) ION, Nitrile hydratase alpha subunit, ... | | 著者 | Van Wyk, J.C, Sewell, B.T, Cowan, D.A, Sayed, M.F, Tsekoa, T.L, Tastan Bishop, A.O. | | 登録日 | 2009-05-17 | | 公開日 | 2009-07-14 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.16 Å) | | 主引用文献 | The high-resolution structure of a Cobalt containing nitrile hydratase
To be published
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1CO4
 | | SOLUTION STRUCTURE OF A ZINC DOMAIN CONSERVED IN YEAST COPPER-REGULATED TRANSCRIPTION FACTORS | | 分子名称: | PROTEIN (ACTIVATOR OF METALLOTHIONEIN 1), ZINC ION | | 著者 | Turner, R.B, Smith, D.L, Zawrotny, M.E, Summers, M.F, Posewitz, M.C, Winge, D.R. | | 登録日 | 1999-06-04 | | 公開日 | 1999-06-10 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of a zinc domain conserved in yeast copper-regulated transcription factors.
Nat.Struct.Biol., 5, 1998
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1AAF
 | | NUCLEOCAPSID ZINC FINGERS DETECTED IN RETROVIRUSES: EXAFS STUDIES ON INTACT VIRUSES AND THE SOLUTION-STATE STRUCTURE OF THE NUCLEOCAPSID PROTEIN FROM HIV-1 | | 分子名称: | HIV-1 NUCLEOCAPSID PROTEIN, ZINC ION | | 著者 | Summers, M.F, Henderson, L.E, Chance, M.R, Bess Junior, J.W, South, T.L, Blake, P.R, Sagi, I, Perez-Alvarado, G, Sowder, R.C, Hare, D.R, Arthur, L.O. | | 登録日 | 1992-04-06 | | 公開日 | 1994-01-31 | | 最終更新日 | 2024-04-10 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Nucleocapsid zinc fingers detected in retroviruses: EXAFS studies of intact viruses and the solution-state structure of the nucleocapsid protein from HIV-1.
Protein Sci., 1, 1992
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3FLG
 | | The PWWP domain of Human DNA (cytosine-5-)-methyltransferase 3 beta | | 分子名称: | DNA (cytosine-5)-methyltransferase 3B | | 著者 | Amaya, M.F, Zeng, H, MacKenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Botchkarev, A, Min, J, Wu, H, Structural Genomics Consortium (SGC) | | 登録日 | 2008-12-18 | | 公開日 | 2009-03-31 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal Structure of the PWWP domain of Human DNA (cytosine-5-)-methyltransferase 3 beta
To be Published
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1A3B
 | | COMPLEX OF HUMAN ALPHA-THROMBIN WITH THE BIFUNCTIONAL BORONATE INHIBITOR BOROLOG1 | | 分子名称: | ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), Hirudin, ... | | 著者 | Skordalakes, E, Elgendy, S, Dodson, G, Goodwin, C.A, Green, D, Scully, M.F, Freyssinet, J.H, Kakkar, V.V, Deadman, J. | | 登録日 | 1998-01-20 | | 公開日 | 1998-06-03 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Bifunctional peptide boronate inhibitors of thrombin: crystallographic analysis of inhibition enhanced by linkage to an exosite 1 binding peptide.
Biochemistry, 37, 1998
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1C72
 | | TYR115, GLN165 AND TRP209 CONTRIBUTE TO THE 1,2-EPOXY-3-(P-NITROPHENOXY)PROPANE CONJUGATING ACTIVITIES OF GLUTATHIONE S-TRANSFERASE CGSTM1-1 | | 分子名称: | 1-HYDROXY-2-S-GLUTATHIONYL-3-PARA-NITROPHENOXY-PROPANE, PROTEIN (GLUTATHIONE S-TRANSFERASE) | | 著者 | Chern, M.K, Wu, T.C, Hsieh, C.H, Chou, C.C, Liu, L.F, Kuan, I.C, Yeh, Y.H, Hsiao, C.D, Tam, M.F. | | 登録日 | 2000-02-02 | | 公開日 | 2000-08-30 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Tyr115, gln165 and trp209 contribute to the 1, 2-epoxy-3-(p-nitrophenoxy)propane-conjugating activity of glutathione S-transferase cGSTM1-1.
J.Mol.Biol., 300, 2000
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1B8T
 | | SOLUTION STRUCTURE OF THE CHICKEN CRP1 | | 分子名称: | PROTEIN (CRP1), ZINC ION | | 著者 | Yao, X, Perez-Alvarado, G.C, Louis, H.A, Pomies, P, Hatt, C, Summers, M.F, Beckerle, M.C. | | 登録日 | 1999-02-02 | | 公開日 | 1999-05-06 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the chicken cysteine-rich protein, CRP1, a double-LIM protein implicated in muscle differentiation.
Biochemistry, 38, 1999
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1CW9
 | | DNA DECAMER WITH AN ENGINEERED CROSSLINK IN THE MINOR GROOVE | | 分子名称: | 5'-D(*CP*CP*AP*GP*(G47)P*CP*CP*TP*GP*G)-3', CALCIUM ION | | 著者 | van Aalten, D.M.F, Erlanson, D.A, Verdine, G.L, Joshua-Tor, L. | | 登録日 | 1999-08-26 | | 公開日 | 1999-10-14 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | A structural snapshot of base-pair opening in DNA.
Proc.Natl.Acad.Sci.USA, 96, 1999
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1D7E
 | | CRYSTAL STRUCTURE OF THE P65 CRYSTAL FORM OF PHOTOACTIVE YELLOW PROTEIN | | 分子名称: | 4'-HYDROXYCINNAMIC ACID, PHOTOACTIVE YELLOW PROTEIN | | 著者 | Van Aalten, D.M.F, Crielaard, W, Hellingwerf, K.J, Joshua-Tor, L. | | 登録日 | 1999-10-17 | | 公開日 | 2000-03-31 | | 最終更新日 | 2018-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.39 Å) | | 主引用文献 | Conformational substates in different crystal forms of the photoactive yellow protein--correlation with theoretical and experimental flexibility.
Protein Sci., 9, 2000
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1D1D
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1CTL
 | | STRUCTURE OF THE CARBOXY-TERMINAL LIM DOMAIN FROM THE CYSTEINE RICH PROTEIN CRP | | 分子名称: | AVIAN CYSTEINE RICH PROTEIN, ZINC ION | | 著者 | Perez-Alvarado, G.C, Miles, C, Michelsen, J.W, Louis, H.A, Winge, D.R, Beckerle, M.C, Summers, M.F. | | 登録日 | 1995-01-06 | | 公開日 | 1995-06-03 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the carboxy-terminal LIM domain from the cysteine rich protein CRP.
Nat.Struct.Biol., 1, 1994
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1A3E
 | | COMPLEX OF HUMAN ALPHA-THROMBIN WITH THE BIFUNCTIONAL BORONATE INHIBITOR BOROLOG2 | | 分子名称: | ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), BOROLOG2, ... | | 著者 | Skordalakes, E, Elgendy, S, Goodwin, C.A, Green, D, Scullly, M.F, Kakkar, V.V, Freyssinet, J.M, Dodson, G, Deadman, J. | | 登録日 | 1998-01-21 | | 公開日 | 1998-06-03 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Bifunctional peptide boronate inhibitors of thrombin: crystallographic analysis of inhibition enhanced by linkage to an exosite 1 binding peptide.
Biochemistry, 37, 1998
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1CPB
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3H8Z
 | | The Crystal Structure of the Tudor Domains from FXR2 | | 分子名称: | Fragile X mental retardation syndrome-related protein 2 | | 著者 | Amaya, M.F, Dong, A, Adams-Cioaba, M.A, Guo, Y, MacKenzie, F, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2009-04-29 | | 公開日 | 2009-06-16 | | 最終更新日 | 2017-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Structural Studies of the Tandem Tudor Domains of Fragile X Mental Retardation Related Proteins FXR1 and FXR2.
Plos One, 5, 2010
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