4RMO
 
 | | Crystal Structure of the CptIN Type III Toxin-Antitoxin System from Eubacterium rectale | | Descriptor: | CALCIUM ION, CptN Toxin, RNA (45-MER) | | Authors: | Rao, F, Voss, J.E, Short, F.L, Luisi, B.F. | | Deposit date: | 2014-10-21 | | Release date: | 2015-09-30 | | Last modified: | 2015-11-18 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Co-evolution of quaternary organization and novel RNA tertiary interactions revealed in the crystal structure of a bacterial protein-RNA toxin-antitoxin system.
Nucleic Acids Res., 43, 2015
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8BVJ
 | | Hfq-Crc-estA translation repression complex | | Descriptor: | Catabolite repression control protein, RNA-binding protein Hfq, estA mRNA | | Authors: | Dendooven, T, Luisi, B.F. | | Deposit date: | 2022-12-04 | | Release date: | 2023-01-25 | | Last modified: | 2023-02-08 | | Method: | ELECTRON MICROSCOPY (4.5 Å) | | Cite: | Translational regulation by Hfq-Crc assemblies emerges from polymorphic ribonucleoprotein folding.
Embo J., 42, 2023
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6GWK
 | | The crystal structure of Hfq from Caulobacter crescentus | | Descriptor: | RNA-binding protein Hfq | | Authors: | Santiago-Frangos, A, Frohlich, K.S, Jeliazkov, J.R, Gray, J.R, Luisi, B.F, Woodson, S.A, Hardwick, S.W. | | Deposit date: | 2018-06-25 | | Release date: | 2019-05-22 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Caulobacter crescentusHfq structure reveals a conserved mechanism of RNA annealing regulation.
Proc.Natl.Acad.Sci.USA, 116, 2019
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4CDI
 | | Crystal structure of AcrB-AcrZ complex | | Descriptor: | ACRIFLAVINE RESISTANCE PROTEIN B, PREDICTED PROTEIN | | Authors: | Du, D, James, N, Klimont, E, Luisi, B.F. | | Deposit date: | 2013-10-31 | | Release date: | 2014-04-30 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.7 Å) | | Cite: | Structure of the Acrab-Tolc Multidrug Efflux Pump.
Nature, 509, 2014
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4C48
 | | Crystal structure of AcrB-AcrZ complex | | Descriptor: | ACRIFLAVINE RESISTANCE PROTEIN B, DARPIN, DODECYL-BETA-D-MALTOSIDE, ... | | Authors: | Du, D, James, N, Klimont, E, Luisi, B.F. | | Deposit date: | 2013-09-02 | | Release date: | 2014-04-30 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Structure of the AcrAB-TolC multidrug efflux pump.
Nature, 509, 2014
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4OXP
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1IBE
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5A0T
 | | Catalysis and 5' end sensing by ribonuclease RNase J of the metallo- beta-lactamase family | | Descriptor: | 5'-R(*CP*GP*CP*CP*UP)-3', DI(HYDROXYETHYL)ETHER, RIBONUCLEASE J, ... | | Authors: | Pei, X.Y, Bralley, P, Jones, G.H, Luisi, B.F. | | Deposit date: | 2015-04-22 | | Release date: | 2015-08-19 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.283 Å) | | Cite: | Linkage of Catalysis and 5' End Recognition in Ribonuclease Rnase J
Nucleic Acids Res., 43, 2015
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5AOH
 | | Crystal Structure of CarF | | Descriptor: | POTASSIUM ION, Spore coat protein CotH | | Authors: | Tichy, E.M, Hardwick, S.W, Luisi, B.F, C Salmond, G.P. | | Deposit date: | 2015-09-10 | | Release date: | 2017-01-25 | | Last modified: | 2019-09-25 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | 1.8 angstrom resolution crystal structure of the carbapenem intrinsic resistance protein CarF.
Acta Crystallogr D Struct Biol, 73, 2017
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5FT0
 | | Crystal structure of gp37(Dip) from bacteriophage phiKZ | | Descriptor: | ARGININE, GP37, POTASSIUM ION | | Authors: | Van den Bossche, A, Hardwick, S.W, Ceyssens, P.J, Hendrix, H, Voet, M, Dendooven, T, Bandyra, K.J, De Maeyer, M, Aertsen, A, Noben, J.P, Luisi, B.F, Lavigne, R. | | Deposit date: | 2016-01-08 | | Release date: | 2016-08-03 | | Last modified: | 2017-03-22 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural elucidation of a novel mechanism for the bacteriophage-based inhibition of the RNA degradosome.
Elife, 5, 2016
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8BVM
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5A0V
 | | Catalysis and 5' end sensing by ribonuclease RNase J of the metallo- beta-lactamase family | | Descriptor: | 5'-R(*CP*GP*CP*CP*UP*CP)-3', CYTIDINE-5'-MONOPHOSPHATE, RIBONUCLEASE J, ... | | Authors: | Pei, X.Y, Bralley, P, Jones, G.H, Luisi, B.F. | | Deposit date: | 2015-04-23 | | Release date: | 2015-08-19 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Linkage of Catalysis and 5' End Recognition in Ribonuclease Rnase J
Nucleic Acids Res., 43, 2015
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8BVH
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1LR0
 | | Pseudomonas aeruginosa TolA Domain III, Seleno-methionine Derivative | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, TolA protein, ZINC ION | | Authors: | Witty, M, Sanz, C, Shah, A, Grossman, J.G, Mizuguchi, K, Perham, R.N, Luisi, B. | | Deposit date: | 2002-05-14 | | Release date: | 2002-05-29 | | Last modified: | 2022-12-21 | | Method: | X-RAY DIFFRACTION (1.914 Å) | | Cite: | Structure of the periplasmic domain of Pseudomonas aeruginosa TolA: evidence for an evolutionary relationship with the TonB transporter protein.
EMBO J., 21, 2002
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4QKK
 | | Crystal structure of an oligonucleotide containing 5-formylcytosine | | Descriptor: | DNA (5'-D(*CP*TP*AP*(5FC)P*GP*(5FC)P*GP*(5FC)P*GP*TP*AP*G)-3') | | Authors: | Raiber, E.-A, Murat, P, Chirgadze, D.Y, Luisi, B.F, Balasubramanian, S. | | Deposit date: | 2014-06-06 | | Release date: | 2014-12-10 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | 5-Formylcytosine alters the structure of the DNA double helix.
Nat.Struct.Mol.Biol., 22, 2015
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5F6C
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5FT1
 | | Crystal structure of gp37(Dip) from bacteriophage phiKZ bound to RNase E of Pseudomonas aeruginosa | | Descriptor: | GP37, RIBONUCLEASE E | | Authors: | Van den Bossche, A, Hardwick, S.W, Ceyssens, P.J, Hendrix, H, Voet, M, Dendooven, T, Bandyra, K.J, De Maeyer, M, Aertsen, A, Noben, J.P, Luisi, B.F, Lavigne, R. | | Deposit date: | 2016-01-08 | | Release date: | 2016-08-03 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Structural elucidation of a novel mechanism for the bacteriophage-based inhibition of the RNA degradosome.
Elife, 5, 2016
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6O1L
 | | Architectural principles for Hfq/Crc-mediated regulation of gene expression Hfq-Crc-amiE 2:3:2 complex | | Descriptor: | Catabolite repression control protein, RNA (5'-R(*AP*AP*AP*AP*AP*UP*AP*AP*CP*AP*AP*CP*AP*AP*GP*AP*GP*G)-3'), RNA-binding protein Hfq | | Authors: | Pei, X.Y, Dendooven, T, Sonnleitner, E, Chen, S, Blasi, U, Luisi, B.F. | | Deposit date: | 2019-02-20 | | Release date: | 2019-03-13 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.37 Å) | | Cite: | Architectural principles for Hfq/Crc-mediated regulation of gene expression.
Elife, 8, 2019
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6O1K
 | | Architectural principles for Hfq/Crc-mediated regulation of gene expression. Hfq-Crc-amiE 2:2:2 complex (core complex) | | Descriptor: | Catabolite repression control protein, RNA (5'-R(*AP*AP*AP*AP*AP*UP*AP*AP*CP*AP*AP*CP*AP*AP*GP*AP*GP*G)-3'), RNA-binding protein Hfq | | Authors: | Pei, X.Y, Dendooven, T, Sonnleitner, E, Chen, S, Blasi, U, Luisi, B.F. | | Deposit date: | 2019-02-20 | | Release date: | 2019-03-13 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.13 Å) | | Cite: | Architectural principles for Hfq/Crc-mediated regulation of gene expression
Elife, 8, 2019
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5V5S
 | | multi-drug efflux; membrane transport; RND superfamily; Drug resistance | | Descriptor: | Multidrug efflux pump subunit AcrA, Multidrug efflux pump subunit AcrB, Outer membrane protein TolC | | Authors: | wang, Z, fan, G, Hryc, C.F, Blaza, J.N, Serysheva, I.I, Schmid, M.F, Chiu, W, Luisi, B.F, Du, D. | | Deposit date: | 2017-03-15 | | Release date: | 2017-04-19 | | Last modified: | 2019-10-23 | | Method: | ELECTRON MICROSCOPY (6.5 Å) | | Cite: | An allosteric transport mechanism for the AcrAB-TolC Multidrug Efflux Pump.
Elife, 6, 2017
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5NC5
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6O1M
 | | Architectural principles for Hfq/Crc-mediated regulation of gene expression. Hfq-Crc-amiE 2:4:2 complex | | Descriptor: | Catabolite repression control protein, RNA (5'-R(*AP*AP*AP*AP*AP*UP*AP*AP*CP*AP*AP*CP*AP*AP*GP*AP*GP*G)-3'), RNA-binding protein Hfq | | Authors: | Pei, X.Y, Dendooven, T, Sonnleitner, E, Chen, S, Blasi, U, Luisi, B.F. | | Deposit date: | 2019-02-20 | | Release date: | 2019-03-13 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.15 Å) | | Cite: | Architectural principles for Hfq/Crc-mediated regulation of gene expression.
Elife, 8, 2019
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1P7J
 | | Crystal structure of engrailed homeodomain mutant K52E | | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Segmentation polarity homeobox protein engrailed | | Authors: | Stollar, E.J, Mayor, U, Lovell, S.C, Federici, L, Freund, S.M, Fersht, A.R, Luisi, B.F. | | Deposit date: | 2003-05-02 | | Release date: | 2003-10-14 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal Structures of Engrailed Homeodomain Mutants: IMPLICATIONS FOR STABILITY AND DYNAMICS
J.Biol.Chem., 278, 2003
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4O7J
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1P7I
 | | CRYSTAL STRUCTURE OF ENGRAILED HOMEODOMAIN MUTANT K52A | | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Segmentation polarity homeobox protein engrailed | | Authors: | Stollar, E.J, Mayor, U, Lovell, S.C, Federici, L, Freund, S.M, Fersht, A.R, Luisi, B.F. | | Deposit date: | 2003-05-02 | | Release date: | 2003-10-14 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal Structures of Engrailed Homeodomain Mutants: IMPLICATIONS FOR STABILITY AND DYNAMICS
J.Biol.Chem., 278, 2003
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