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PDB: 28 results

5EOO
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BU of 5eoo by Molmil
Crystal structure of extended-spectrum beta-lactamase BEL-1 (monoclinic form)
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, Beta-lactamase, CHLORIDE ION, ...
Authors:Pozzi, C, De Luca, F, Benvenuti, M, Docquier, J.D, Mangani, S.
Deposit date:2015-11-10
Release date:2016-09-21
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Crystal Structure of the Pseudomonas aeruginosa BEL-1 Extended-Spectrum beta-Lactamase and Its Complexes with Moxalactam and Imipenem.
Antimicrob.Agents Chemother., 60, 2016
4GZB
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Crystal structure of native AmpC beta-lactamase from Pseudomonas aeruginosa PAO1
Descriptor: 1,2-ETHANEDIOL, Beta-lactamase
Authors:Benvenuti, M, De Luca, F, Docquier, J.D, Mangani, S.
Deposit date:2012-09-06
Release date:2013-04-10
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Structural insight into potent broad-spectrum inhibition with reversible recyclization mechanism: avibactam in complex with CTX-M-15 and Pseudomonas aeruginosa AmpC beta-lactamases
Antimicrob.Agents Chemother., 57, 2013
6ZXI
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Crystal Structure of the OXA-48 Carbapenem-Hydrolyzing Class D beta-Lactamase in Complex with the DBO inhibitor ANT3310
Descriptor: 1,2-ETHANEDIOL, Beta-lactamase, CARBON DIOXIDE, ...
Authors:Docquier, J.D, Pozzi, C, De Luca, F, Benvenuti, M, Mangani, S.
Deposit date:2020-07-29
Release date:2021-08-11
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Discovery of ANT3310 , a Novel Broad-Spectrum Serine beta-Lactamase Inhibitor of the Diazabicyclooctane Class, Which Strongly Potentiates Meropenem Activity against Carbapenem-Resistant Enterobacterales and Acinetobacter baumannii.
J.Med.Chem., 63, 2020
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