4GZB
Crystal structure of native AmpC beta-lactamase from Pseudomonas aeruginosa PAO1
Summary for 4GZB
| Entry DOI | 10.2210/pdb4gzb/pdb |
| Related | 4HBT 4HBU 4HEF |
| Descriptor | Beta-lactamase, 1,2-ETHANEDIOL (3 entities in total) |
| Functional Keywords | beta-lactamase fold, hydrolase, antibiotic resistance |
| Biological source | Pseudomonas aeruginosa |
| Cellular location | Periplasm (By similarity): P24735 |
| Total number of polymer chains | 1 |
| Total formula weight | 40786.03 |
| Authors | Benvenuti, M.,De Luca, F.,Docquier, J.D.,Mangani, S. (deposition date: 2012-09-06, release date: 2013-04-10, Last modification date: 2023-11-08) |
| Primary citation | Lahiri, S.D.,Mangani, S.,Durand-Reville, T.,Benvenuti, M.,De Luca, F.,Sanyal, G.,Docquier, J.D. Structural insight into potent broad-spectrum inhibition with reversible recyclization mechanism: avibactam in complex with CTX-M-15 and Pseudomonas aeruginosa AmpC beta-lactamases Antimicrob.Agents Chemother., 57:2496-2505, 2013 Cited by PubMed: 23439634DOI: 10.1128/AAC.02247-12 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.79 Å) |
Structure validation
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