3C1C
| The effect of H3 K79 dimethylation and H4 K20 trimethylation on nucleosome and chromatin structure | Descriptor: | Histone 2, H2bf, Histone H2A type 1, ... | Authors: | Lu, X, Simon, M, Chodaparambil, J, Hansen, J, Shokat, K, Luger, K. | Deposit date: | 2008-01-22 | Release date: | 2008-10-07 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | The effect of H3K79 dimethylation and H4K20 trimethylation on nucleosome and chromatin structure. Nat.Struct.Mol.Biol., 15, 2008
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4FIU
| The structure of hemagglutinin of H16 subtype influenza virus with V327G mutation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, hemagglutinin | Authors: | Lu, X, Shi, Y, Gao, F, Xiao, H, Wang, M, Qi, J, Gao, G.F. | Deposit date: | 2012-06-11 | Release date: | 2012-11-21 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.999 Å) | Cite: | Insights into Avian Influenza Virus Pathogenicity: the Hemagglutinin Precursor HA0 of Subtype H16 Has an Alpha-Helix Structure in Its Cleavage Site with Inefficient HA1/HA2 Cleavage. J.Virol., 86, 2012
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5HM4
| Crystal structure of oligopeptide ABC transporter, periplasmic oligopeptide-binding protein (TM1226) from THERMOTOGA MARITIMA at 2.0 A resolution | Descriptor: | CALCIUM ION, Mannoside ABC transport system, sugar-binding protein | Authors: | Lu, X, Ghimire-Rijal, S, Myles, D.A.A, Cuneo, M.J. | Deposit date: | 2016-01-15 | Release date: | 2016-11-23 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Periplasmic Binding Protein Dimer Has a Second Allosteric Event Tied to Ligand Binding. Biochemistry, 56, 2017
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2R7S
| Crystal Structure of Rotavirus SA11 VP1 / RNA (UGUGCC) complex | Descriptor: | PHOSPHATE ION, RNA (5'-R(*UP*GP*UP*GP*CP*C)-3'), RNA-dependent RNA polymerase | Authors: | Lu, X, Harrison, S.C, Tao, Y.J, Patton, J.T, Nibert, M.L. | Deposit date: | 2007-09-10 | Release date: | 2008-07-29 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.24 Å) | Cite: | Mechanism for coordinated RNA packaging and genome replication by rotavirus polymerase VP1. Structure, 16, 2008
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5H8Z
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2R7R
| Crystal Structure of Rotavirus SA11 VP1/RNA (UGUGACC) complex | Descriptor: | RNA (5'-R(*UP*GP*UP*GP*AP*CP*C)-3'), RNA-dependent RNA polymerase | Authors: | Lu, X, Harrison, S.C, Tao, Y.J, Patton, J.T, Nibert, M.L. | Deposit date: | 2007-09-09 | Release date: | 2008-07-29 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Mechanism for coordinated RNA packaging and genome replication by rotavirus polymerase VP1. Structure, 16, 2008
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2R7T
| Crystal Structure of Rotavirus SA11 VP1/RNA (UGUGAACC) Complex | Descriptor: | RNA (5'-R(*UP*GP*UP*GP*AP*AP*CP*C)-3'), RNA-dependent RNA polymerase | Authors: | Lu, X, Harrison, S.C, Tao, Y.J, Patton, J.T, Nibert, M.L. | Deposit date: | 2007-09-10 | Release date: | 2008-07-29 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Mechanism for coordinated RNA packaging and genome replication by rotavirus polymerase VP1. Structure, 16, 2008
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2R7V
| Crystal Structure of Rotavirus SA11 VP1/RNA (GGCUUU) Complex | Descriptor: | RNA (5'-R(*G*GP*CP*UP*UP*U)-3'), RNA-dependent RNA polymerase | Authors: | Lu, X, Harrison, S.C, Tao, Y.J, Patton, J.T, Nibert, M.L. | Deposit date: | 2007-09-10 | Release date: | 2008-07-29 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Mechanism for coordinated RNA packaging and genome replication by rotavirus polymerase VP1. Structure, 16, 2008
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2R7U
| Crystal Structure of Rotavirus SA11 VP1/RNA (AAAAGCC) Complex | Descriptor: | RNA (5'-R(*AP*A*AP*AP*GP*CP*C)-3'), RNA-dependent RNA polymerase | Authors: | Lu, X, Harrison, S.C, Tao, Y.J, Patton, J.T, Nibert, M.L. | Deposit date: | 2007-09-10 | Release date: | 2008-07-29 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Mechanism for coordinated RNA packaging and genome replication by rotavirus polymerase VP1. Structure, 16, 2008
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2R7X
| Crystal Structure of Rotavirus SA11 VP1/RNA (UGUGACC)/GTP complex | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, RNA (5'-R(*UP*GP*UP*GP*AP*CP*C)-3'), RNA-dependent RNA polymerase | Authors: | Lu, X, Harrison, S.C, Tao, Y.J, Patton, J.T, Nibert, M.L. | Deposit date: | 2007-09-10 | Release date: | 2008-07-29 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Mechanism for coordinated RNA packaging and genome replication by rotavirus polymerase VP1. Structure, 16, 2008
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2R7W
| Crystal Structure of Rotavirus SA11 VP1/RNA (UGUGACC)/mRNA 5'-CAP (m7GpppG) complex | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, RNA (5'-R(*UP*GP*UP*GP*AP*CP*C)-3'), RNA-dependent RNA polymerase | Authors: | Lu, X, Harrison, S.C, Tao, Y.J, Patton, J.T, Nibert, M.L. | Deposit date: | 2007-09-10 | Release date: | 2008-07-29 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Mechanism for coordinated RNA packaging and genome replication by rotavirus polymerase VP1. Structure, 16, 2008
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8E6O
| Crystal structure of human GCN5 histone acetyltransferase domain | Descriptor: | Histone acetyltransferase KAT2A, S-{(3S,5R,9R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-3,5,10,14-tetraoxo-2,4,6-trioxa-11,15-diaza-3lambda~5~,5lambda~5~-diphosphaheptadecan-17-yl} (2R)-2-hydroxypropanethioate | Authors: | Lu, X.T, Tao, Y.J. | Deposit date: | 2022-08-23 | Release date: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.37 Å) | Cite: | Crystal structure of human GCN5 histone acetyltransferase domain To Be Published
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2R7O
| Crystal Structure of VP1 apoenzyme of Rotavirus SA11 (N-terminal hexahistidine-tagged) | Descriptor: | RNA-dependent RNA polymerase | Authors: | Lu, X, Harrison, S.C, Tao, Y.J, Patton, J.T, Nibert, M.L. | Deposit date: | 2007-09-09 | Release date: | 2008-07-29 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.35 Å) | Cite: | Mechanism for coordinated RNA packaging and genome replication by rotavirus polymerase VP1. Structure, 16, 2008
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2R7Q
| Crystal Structure of VP1 apoenzyme of Rotavirus SA11 (C-terminal hexahistidine-tagged) | Descriptor: | RNA-dependent RNA polymerase | Authors: | Lu, X, Harrison, S.C, Tao, Y.J, Patton, J.T, Nibert, M.L. | Deposit date: | 2007-09-09 | Release date: | 2008-07-29 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Mechanism for coordinated RNA packaging and genome replication by rotavirus polymerase VP1. Structure, 16, 2008
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3C1B
| The effect of H3 K79 dimethylation and H4 K20 trimethylation on nucleosome and chromatin structure | Descriptor: | Histone 2, H2bf, Histone H2A type 1, ... | Authors: | Lu, X, Simon, M, Chodaparambil, J, Hansen, J, Shokat, K, Luger, K. | Deposit date: | 2008-01-22 | Release date: | 2008-10-07 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The effect of H3K79 dimethylation and H4K20 trimethylation on nucleosome and chromatin structure. Nat.Struct.Mol.Biol., 15, 2008
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6IW2
| Crystal structure of 5A ScFv in complex with YFV-17D sE in prefusion state | Descriptor: | Envelope protein E, Heavy chain of monoclonal antibody 5A, Light chain of monoclonal antibody 5A | Authors: | Lu, X.S, Xiao, H.X, Li, S.H, Pang, X.F. | Deposit date: | 2018-12-04 | Release date: | 2019-02-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Double Lock of a Human Neutralizing and Protective Monoclonal Antibody Targeting the Yellow Fever Virus Envelope. Cell Rep, 26, 2019
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6IW5
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6IVZ
| Crystal structure of 5A ScFv complexed with YFV-China sE in postfusion state | Descriptor: | Envelope protein, Heavy chain of monoclonal antibody 5A, Light chain of monoclonal antibody 5A | Authors: | Lu, X.S, Xiao, H.X, Li, S.H, Pang, X.F. | Deposit date: | 2018-12-04 | Release date: | 2019-02-13 | Last modified: | 2019-02-27 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Double Lock of a Human Neutralizing and Protective Monoclonal Antibody Targeting the Yellow Fever Virus Envelope. Cell Rep, 26, 2019
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6IW0
| Crystal structure of 5A ScFv in complex with YFV-17D sE in postfusion state | Descriptor: | Envelope protein E, Heavy chain of monoclonal antibody 5A, Light chain of monoclonal antibody 5A | Authors: | Lu, X.S, Xiao, H.X, Li, S.H, Pang, X.F. | Deposit date: | 2018-12-04 | Release date: | 2019-02-13 | Last modified: | 2019-02-27 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Double Lock of a Human Neutralizing and Protective Monoclonal Antibody Targeting the Yellow Fever Virus Envelope. Cell Rep, 26, 2019
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6IW4
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4PFU
| Crystal structure of mannobiose bound oligopeptide ABC transporter, periplasmic oligopeptide-binding protein (TM1226) from THERMOTOGA MARITIMA at 2.05 A resolution | Descriptor: | ABC transporter substrate-binding protein, MAGNESIUM ION, SULFATE ION, ... | Authors: | Lu, X, Ghimire-Rijal, S, Cuneo, M.J. | Deposit date: | 2014-04-30 | Release date: | 2014-09-17 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.049 Å) | Cite: | Duplication of Genes in an ATP-binding Cassette Transport System Increases Dynamic Range While Maintaining Ligand Specificity. J.Biol.Chem., 289, 2014
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6IW1
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4EOT
| Crystal structure of the MafA homodimer bound to the consensus MARE | Descriptor: | 5'-D(*CP*CP*CP*TP*GP*CP*TP*GP*AP*CP*TP*CP*AP*GP*CP*AP*CP*CP*G)-3', 5'-D(*CP*CP*GP*GP*TP*GP*CP*TP*GP*AP*GP*TP*CP*AP*GP*CP*AP*GP*G)-3', SULFATE ION, ... | Authors: | Lu, X, Guanga, G, Wan, C, Rose, R.B. | Deposit date: | 2012-04-15 | Release date: | 2012-11-28 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.855 Å) | Cite: | A Novel DNA Binding Mechanism for maf Basic Region-Leucine Zipper Factors Inferred from a MafA-DNA Complex Structure and Binding Specificities. Biochemistry, 51, 2012
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4F23
| Influenza A virus hemagglutinin H16 HA0 structure with an alpha-helix conformation in the cleavage site: a potential drug target | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin | Authors: | Lu, X, Shi, Y, Gao, F, Xiao, H, Qi, J, Gao, G.F. | Deposit date: | 2012-05-07 | Release date: | 2012-11-21 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Insights into Avian Influenza Virus Pathogenicity: the Hemagglutinin Precursor HA0 of Subtype H16 Has an Alpha-Helix Structure in Its Cleavage Site with Inefficient HA1/HA2 Cleavage. J.Virol., 86, 2012
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4PFT
| Crystal structure of mannobiose bound oligopeptide ABC transporter, periplasmic oligopeptide-binding protein (TM1223) from THERMOTOGA MARITIMA at 1.75 A resolution | Descriptor: | ABC transporter substrate-binding protein, MAGNESIUM ION, NITRATE ION, ... | Authors: | Lu, X, Ghimire-Rijal, S, Cuneo, M.J. | Deposit date: | 2014-04-30 | Release date: | 2014-09-17 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.747 Å) | Cite: | Duplication of Genes in an ATP-binding Cassette Transport System Increases Dynamic Range While Maintaining Ligand Specificity. J.Biol.Chem., 289, 2014
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