7ZQX
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![BU of 7zqx by Molmil](/molmil-images/mine/7zqx) | Human galectin-3c in complex with a galactose derivative | Descriptor: | (2~{R},3~{R},4~{S},5~{R},6~{R})-2-(5-bromanylpyridin-3-yl)sulfanyl-6-(hydroxymethyl)-4-[4-[3,4,5-tris(fluoranyl)phenyl]-1,2,3-triazol-1-yl]oxane-3,5-diol, CHLORIDE ION, GLYCEROL, ... | Authors: | Zetterberg, F, Nilsson, U.J, Hakansson, M, Logan, D.T. | Deposit date: | 2022-05-03 | Release date: | 2022-11-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Discovery and Optimization of the First Highly Effective and Orally Available Galectin-3 Inhibitors for Treatment of Fibrotic Disease. J.Med.Chem., 65, 2022
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1XJE
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![BU of 1xje by Molmil](/molmil-images/mine/1xje) | Structural mechanism of allosteric substrate specificity in a ribonucleotide reductase: dTTP-GDP complex | Descriptor: | GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Larsson, K.-M, Jordan, A, Eliasson, R, Reichard, P, Logan, D.T, Nordlund, P. | Deposit date: | 2004-09-23 | Release date: | 2005-10-11 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural mechanism of allosteric substrate specificity regulation in a ribonucleotide reductase. Nat.Struct.Mol.Biol., 11, 2004
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1XJM
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![BU of 1xjm by Molmil](/molmil-images/mine/1xjm) | Structural mechanism of allosteric substrate specificity in a ribonucleotide reductase: dTTP complex | Descriptor: | MAGNESIUM ION, THYMIDINE-5'-TRIPHOSPHATE, ribonucleotide reductase, ... | Authors: | Larsson, K.-M, Jordan, A, Eliasson, R, Reichard, P, Logan, D.T, Nordlund, P. | Deposit date: | 2004-09-23 | Release date: | 2005-12-20 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural mechanism of allosteric substrate specificity regulation in a ribonucleotide reductase. Nat.Struct.Mol.Biol., 11, 2004
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1XJG
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![BU of 1xjg by Molmil](/molmil-images/mine/1xjg) | Structural mechanism of allosteric substrate specificity in a ribonucleotide reductase: dATP-UDP complex | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, MAGNESIUM ION, URIDINE-5'-DIPHOSPHATE, ... | Authors: | Larsson, K.-M, Jordan, A, Eliasson, R, Reichard, P, Logan, D.T, Nordlund, P. | Deposit date: | 2004-09-23 | Release date: | 2005-12-20 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural Mechanism of Allosteric Substrate Specificity Regulation in a Ribonucleotide Reductase Nat.Struct.Mol.Biol., 11, 2004
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1XJJ
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![BU of 1xjj by Molmil](/molmil-images/mine/1xjj) | Structural mechanism of allosteric substrate specificity in a ribonucleotide reductase: dGTP complex | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ribonucleotide reductase, ... | Authors: | Larsson, K.-M, Jordan, A, Eliasson, R, Reichard, P, Logan, D.T, Nordlund, P. | Deposit date: | 2004-09-23 | Release date: | 2005-12-20 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Structural Mechanism of Allosteric Substrate Specificity Regulation in a Ribonucleotide Reductase Nat.Struct.Mol.Biol., 11, 2005
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1XJN
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![BU of 1xjn by Molmil](/molmil-images/mine/1xjn) | Structural mechanism of allosteric substrate specificity in a ribonucleotide reductase: dATP-CDP complex | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CHLORIDE ION, CYTIDINE-5'-DIPHOSPHATE, ... | Authors: | Larsson, K.-M, Jordan, A, Eliasson, R, Reichard, P, Logan, D.T, Nordlund, P. | Deposit date: | 2004-09-23 | Release date: | 2005-12-06 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural Mechanism of Allosteric Substrate Specificity Regulation in a Ribonucleotide Reductase Nat.Struct.Mol.Biol., 11, 2004
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1XJK
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![BU of 1xjk by Molmil](/molmil-images/mine/1xjk) | Structural mechanism of allosteric substrate specificity in a ribonucleotide reductase: dGTP-ADP complex | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Larsson, K.-M, Jordan, A, Eliasson, R, Reichard, P, Logan, D.T, Nordlund, P. | Deposit date: | 2004-09-23 | Release date: | 2005-11-22 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.12 Å) | Cite: | Structural mechanism of allosteric substrate specificity regulation in a ribonucleotide reductase. Nat.Struct.Mol.Biol., 11, 2004
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1XJF
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![BU of 1xjf by Molmil](/molmil-images/mine/1xjf) | Structural mechanism of allosteric substrate specificity in a ribonucleotide reductase: dATP complex | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, MAGNESIUM ION, ribonucleotide reductase, ... | Authors: | Larsson, K.-M, Jordan, A, Eliasson, R, Reichard, P, Logan, D.T, Nordlund, P. | Deposit date: | 2004-09-23 | Release date: | 2005-12-20 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural mechanism of allosteric substrate specificity regulation in a ribonucleotide reductase. Nat.Struct.Mol.Biol., 11, 2004
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1YFD
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![BU of 1yfd by Molmil](/molmil-images/mine/1yfd) | Crystal structure of the Y122H mutant of ribonucleotide reductase R2 protein from E. coli | Descriptor: | MERCURY (II) ION, MU-OXO-DIIRON, Ribonucleoside-diphosphate reductase 1 beta chain | Authors: | Kolberg, M, Logan, D.T, Bleifuss, G, Poetsch, S, Sjoeberg, B.M, Graeslund, A, Lubitz, W, Lassmann, G, Lendzian, F. | Deposit date: | 2004-12-31 | Release date: | 2005-02-15 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A new tyrosyl radical on Phe208 as ligand to the diiron center in Escherichia coli ribonucleotide reductase, mutant R2-Y122H. Combined x-ray diffraction and EPR/ENDOR studies J.Biol.Chem., 280, 2005
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1H78
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![BU of 1h78 by Molmil](/molmil-images/mine/1h78) | STRUCTURAL BASIS FOR ALLOSTERIC SUBSTRATE SPECIFICITY REGULATION IN CLASS III RIBONUCLEOTIDE REDUCTASES: NRDD IN COMPLEX WITH DCTP. | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, ANAEROBIC RIBONUCLEOTIDE-TRIPHOSPHATE REDUCTASE LARGE CHAIN, MAGNESIUM ION | Authors: | Larsson, K.-M, Andersson, J, Sjoeberg, B.-M, Nordlund, P, Logan, D.T. | Deposit date: | 2001-07-04 | Release date: | 2002-07-04 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural Basis for Allosteric Substrate Specificty Regulation in Anaerobic Ribonucleotide Reductase Structure, 9, 2001
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4ACR
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![BU of 4acr by Molmil](/molmil-images/mine/4acr) | Crystal structure of N-glycosylated, C-terminally truncated human glypican-1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYPICAN-1 | Authors: | Svensson, G, Awad, W, Mani, K, Logan, D.T. | Deposit date: | 2011-12-17 | Release date: | 2012-02-22 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Crystal Structure of N-Glycosylated Human Glypican-1 Core Protein: Structure of Two Loops Evolutionarily Conserved in Vertebrate Glypican-1. J.Biol.Chem., 287, 2012
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4BLI
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![BU of 4bli by Molmil](/molmil-images/mine/4bli) | Galectin-3c in complex with Bisamido-thiogalactoside derivate 1 | Descriptor: | (3-Deoxy-3-(3-methoxy-benzamido)-b-D-galactopyranosyl)-(3-deoxy-3-(3-methoxy-benzamido)-2-O-sulfo-b-D-galactopyranosyl)-sulfide, GALECTIN-3 | Authors: | Noresson, A.L, Oberg, C.T, Engstrom, O, Hakansson, M, Logan, D.T, Leffler, H, Nilsson, U.J. | Deposit date: | 2013-05-03 | Release date: | 2014-05-21 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.08 Å) | Cite: | Controlling Protein Conformation Through Electronic Fine-Tuning of Arginine-Arene Interactions: Synthetic, Structural, and Biological Studies To be Published
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4BLJ
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![BU of 4blj by Molmil](/molmil-images/mine/4blj) | Galectin-3c in complex with Bisamido-thiogalactoside derivate 2 | Descriptor: | Bis-(3-deoxy-3-(3-methoxy-benzamido)-b-D-galactopyranosyl)-sulfide, GALECTIN-3 | Authors: | Noresson, A.L, Oberg, C.T, Engstrom, O, Hakansson, M, Logan, D.T, Leffler, H, Nilsson, U.J. | Deposit date: | 2013-05-03 | Release date: | 2014-05-14 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Controlling Protein Conformation Through Electronic Fine-Tuning of Arginine-Arene Interactions: Synthetic, Structural, and Biological Studies To be Published
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4BM8
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![BU of 4bm8 by Molmil](/molmil-images/mine/4bm8) | Galectin-3c in complex with Bisamido-thiogalactoside derivate 3 | Descriptor: | (3-Deoxy-3-(2,3,5,6-tetra-fluoro-4-methoxy-benzamido)-b-D-galactopyranosyl)-(3-deoxy-3-(2,3,5,6-tetra-fluoro-4-methoxy-benzamido)-2-O-sulfo-b-D-galactopyranosyl)-sulfide, GALECTIN-3 | Authors: | Noresson, A.L, Oberg, C.T, Engstrom, O, Hakansson, M, Logan, D.T, Leffler, H, Nilsson, U.J. | Deposit date: | 2013-05-07 | Release date: | 2014-05-21 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (0.96 Å) | Cite: | Controlling Protein Conformation Through Electronic Fine-Tuning of Arginine-Arene Interactions: Synthetic, Structural, and Biological Studies To be Published
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4BCZ
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![BU of 4bcz by Molmil](/molmil-images/mine/4bcz) | Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form. | Descriptor: | SUPEROXIDE DISMUTASE [CU-ZN] | Authors: | Saraboji, K, Awad, W, Danielsson, J, Lang, L, Kurnik, M, Marklund, S.L, Oliveberg, M, Logan, D.T. | Deposit date: | 2012-10-03 | Release date: | 2013-02-27 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Global Structural Motions from the Strain of a Single Hydrogen Bond. Proc.Natl.Acad.Sci.USA, 110, 2013
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3ZZP
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![BU of 3zzp by Molmil](/molmil-images/mine/3zzp) | Circular permutant of ribosomal protein S6, lacking edge strand beta- 2 of wild-type S6. | Descriptor: | RIBOSOMAL PROTEIN S6 | Authors: | Saraboji, K, Haglund, E, Lindberg, M.O, Oliveberg, M, Logan, D.T. | Deposit date: | 2011-09-02 | Release date: | 2011-11-23 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (0.96 Å) | Cite: | Trimming Down a Protein Structure to its Bare Foldons: Spatial Organization of the Cooperative Unit. J.Biol.Chem., 287, 2012
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4BD4
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![BU of 4bd4 by Molmil](/molmil-images/mine/4bd4) | Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, mutant H43F | Descriptor: | GLYCEROL, SUPEROXIDE DISMUTASE [CU-ZN] | Authors: | Awad, W, Saraboji, K, Danielsson, J, Lang, L, Kurnik, M, Marklund, S.L, Oliveberg, M, Logan, D.T. | Deposit date: | 2012-10-04 | Release date: | 2013-02-27 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.78 Å) | Cite: | Global Structural Motions from the Strain of a Single Hydrogen Bond. Proc.Natl.Acad.Sci.USA, 110, 2013
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4BJ0
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![BU of 4bj0 by Molmil](/molmil-images/mine/4bj0) | Xyloglucan binding module (CBM4-2 X2-L110F) in complex with branched xyloses | Descriptor: | CALCIUM ION, XYLANASE, alpha-D-glucopyranose, ... | Authors: | Schantz, L, Hakansson, M, Logan, D.T, Nordberg-Karlsson, E, Ohlin, M. | Deposit date: | 2013-04-15 | Release date: | 2014-04-23 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | Carbohydrate Binding Module Recognition of Xyloglucan Defined by Polar Contacts with Branching Xyloses and Ch-Pi Interactions. Proteins, 82, 2014
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3ZSM
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![BU of 3zsm by Molmil](/molmil-images/mine/3zsm) | Crystal structure of Apo Human Galectin-3 CRD at 1.25 angstrom resolution, at room temperature | Descriptor: | GALECTIN-3 | Authors: | Saraboji, K, Hakansson, M, Diehl, C, Nilsson, U.J, Leffler, H, Akke, M, Logan, D.T. | Deposit date: | 2011-06-28 | Release date: | 2011-12-14 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | The Carbohydrate-Binding Site in Galectin-3 is Pre-Organized to Recognize a Sugar-Like Framework of Oxygens: Ultra-High Resolution Structures and Water Dynamics. Biochemistry, 51, 2012
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4BCY
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![BU of 4bcy by Molmil](/molmil-images/mine/4bcy) | Monomeric Human Cu,Zn Superoxide dismutase, mutation H43F | Descriptor: | CADMIUM ION, CHLORIDE ION, COPPER (II) ION, ... | Authors: | Awad, W, Saraboji, K, Danielsson, J, Lang, L, Kurnik, M, Marklund, S.L, Oliveberg, M, Logan, D.T. | Deposit date: | 2012-10-03 | Release date: | 2013-02-27 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.272 Å) | Cite: | Global Structural Motions from the Strain of a Single Hydrogen Bond. Proc.Natl.Acad.Sci.USA, 110, 2013
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4AD7
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![BU of 4ad7 by Molmil](/molmil-images/mine/4ad7) | Crystal structure of full-length N-glycosylated human glypican-1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYPICAN-1 | Authors: | Svensson, G, Awad, W, Mani, K, Logan, D.T. | Deposit date: | 2011-12-22 | Release date: | 2012-03-21 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.945 Å) | Cite: | Crystal Structure of N-Glycosylated Human Glypican-1 Core Protein: Structure of Two Loops Evolutionarily Conserved in Vertebrate Glypican-1. J.Biol.Chem., 287, 2012
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4CON
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![BU of 4con by Molmil](/molmil-images/mine/4con) | Crystal structure of the anaerobic ribonucleotide reductase from Thermotoga maritima with citrate in the active site | Descriptor: | ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE, CITRIC ACID | Authors: | Aurelius, O, Johansson, R, Bagenholm, V, Beck, T, Balhuizen, A, Lundin, D, Sjoberg, B.M, Mulliez, E, Logan, D.T. | Deposit date: | 2014-01-29 | Release date: | 2015-01-14 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.12 Å) | Cite: | The Crystal Structure of Thermotoga Maritima Class III Ribonucleotide Reductase Lacks a Radical Cysteine Pre-Positioned in the Active Site. Plos One, 10, 2015
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4COM
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![BU of 4com by Molmil](/molmil-images/mine/4com) | Crystal structure of the anaerobic ribonucleotide reductase from Thermotoga maritima with MES in the active site | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE, PENTAETHYLENE GLYCOL, ... | Authors: | Aurelius, O, Johansson, R, Bagenholm, V, Beck, T, Balhuizen, A, Lundin, D, Sjoberg, B.M, Mulliez, E, Logan, D.T. | Deposit date: | 2014-01-29 | Release date: | 2015-01-14 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | The Crystal Structure of Thermotoga Maritima Class III Ribonucleotide Reductase Lacks a Radical Cysteine Pre-Positioned in the Active Site. Plos One, 10, 2015
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4COL
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![BU of 4col by Molmil](/molmil-images/mine/4col) | Crystal structure of the anaerobic ribonucleotide reductase from Thermotoga maritima with dATP bound in the specificity site | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE, MAGNESIUM ION, ... | Authors: | Aurelius, O, Johansson, R, Bagenholm, V, Beck, T, Balhuizen, A, Lundin, D, Sjoberg, B.M, Mulliez, E, Logan, D.T. | Deposit date: | 2014-01-29 | Release date: | 2015-05-06 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | The Crystal Structure of Thermotoga Maritima Class III Ribonucleotide Reductase Lacks a Radical Cysteine Pre-Positioned in the Active Site. Plos One, 10, 2015
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4COJ
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![BU of 4coj by Molmil](/molmil-images/mine/4coj) | Crystal structure of the anaerobic ribonucleotide reductase from Thermotoga maritima in complex with dATP and CTP | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE, CYTIDINE-5'-TRIPHOSPHATE, ... | Authors: | Aurelius, O, Johansson, R, Bagenholm, V, Beck, T, Balhuizen, A, Lundin, D, Sjoberg, B.M, Mulliez, E, Logan, D.T. | Deposit date: | 2014-01-28 | Release date: | 2015-05-06 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | The Crystal Structure of Thermotoga Maritima Class III Ribonucleotide Reductase Lacks a Radical Cysteine Pre-Positioned in the Active Site. Plos One, 10, 2015
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