1BY3
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![BU of 1by3 by Molmil](/molmil-images/mine/1by3) | FHUA FROM E. COLI | Descriptor: | N-OCTYL-2-HYDROXYETHYL SULFOXIDE, PROTEIN (FERRICHROME-IRON RECEPTOR PRECURSOR (FHUA)) | Authors: | Locher, K.P, Rees, B, Koebnik, R, Mitschler, A, Moulinier, L, Rosenbusch, J.P, Moras, D. | Deposit date: | 1998-10-22 | Release date: | 1999-01-13 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.74 Å) | Cite: | Transmembrane signaling across the ligand-gated FhuA receptor: crystal structures of free and ferrichrome-bound states reveal allosteric changes. Cell(Cambridge,Mass.), 95, 1998
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1BY5
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![BU of 1by5 by Molmil](/molmil-images/mine/1by5) | FHUA FROM E. COLI, WITH ITS LIGAND FERRICHROME | Descriptor: | FE (III) ION, FERRIC HYDROXAMATE UPTAKE PROTEIN, FERRICHROME, ... | Authors: | Locher, K.P, Rees, B, Koebnik, R, Mitschler, A, Moulinier, L, Rosenbusch, J.P, Moras, D. | Deposit date: | 1998-10-23 | Release date: | 1999-01-13 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Transmembrane signaling across the ligand-gated FhuA receptor: crystal structures of free and ferrichrome-bound states reveal allosteric changes. Cell(Cambridge,Mass.), 95, 1998
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1HUX
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![BU of 1hux by Molmil](/molmil-images/mine/1hux) | CRYSTAL STRUCTURE OF THE ACIDAMINOCOCCUS FERMENTANS (R)-2-HYDROXYGLUTARYL-COA DEHYDRATASE COMPONENT A | Descriptor: | ACTIVATOR OF (R)-2-HYDROXYGLUTARYL-COA DEHYDRATASE, ADENOSINE-5'-DIPHOSPHATE, IRON/SULFUR CLUSTER | Authors: | Locher, K.P, Hans, M, Yeh, A.P, Schmid, B, Buckel, W, Rees, D.C. | Deposit date: | 2001-01-04 | Release date: | 2001-03-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structure of the Acidaminococcus fermentans 2-hydroxyglutaryl-CoA dehydratase component A. J.Mol.Biol., 307, 2001
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1L7V
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![BU of 1l7v by Molmil](/molmil-images/mine/1l7v) | Bacterial ABC Transporter Involved in B12 Uptake | Descriptor: | CYCLO-TETRAMETAVANADATE, VITAMIN B12 TRANSPORT SYSTEM PERMEASE PROTEIN BTUC, Vitamin B12 transport ATP-binding protein btuD | Authors: | Locher, K.P, Lee, A.T, Rees, D.C. | Deposit date: | 2002-03-18 | Release date: | 2002-05-15 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | The E. coli BtuCD structure: a framework for ABC transporter architecture and mechanism. Science, 296, 2002
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7RTH
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![BU of 7rth by Molmil](/molmil-images/mine/7rth) | Crystal structure of an anti-lysozyme nanobody in complex with an anti-nanobody Fab "NabFab" | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Fragment Antigen-Binding Heavy Chain, ... | Authors: | Filippova, E.V, Mukherjee, S, Bloch, J.S, Locher, K.P, Kossiakoff, A.A. | Deposit date: | 2021-08-13 | Release date: | 2021-09-01 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.19 Å) | Cite: | Development of a universal nanobody-binding Fab module for fiducial-assisted cryo-EM studies of membrane proteins. Proc.Natl.Acad.Sci.USA, 118, 2021
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2HYD
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![BU of 2hyd by Molmil](/molmil-images/mine/2hyd) | Multidrug ABC transporter SAV1866 | Descriptor: | ABC transporter homolog, ADENOSINE-5'-DIPHOSPHATE, SODIUM ION | Authors: | Dawson, R.J.P, Locher, K.P. | Deposit date: | 2006-08-05 | Release date: | 2006-09-05 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure of a bacterial multidrug ABC transporter. Nature, 443, 2006
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5NO0
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![BU of 5no0 by Molmil](/molmil-images/mine/5no0) | |
1N2Z
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![BU of 1n2z by Molmil](/molmil-images/mine/1n2z) | 2.0 Angstrom structure of BtuF, the vitamin B12 binding protein of E. coli | Descriptor: | CADMIUM ION, CHLORIDE ION, CYANOCOBALAMIN, ... | Authors: | Borths, E.L, Locher, K.P, Lee, A.T, Rees, D.C. | Deposit date: | 2002-10-24 | Release date: | 2002-12-18 | Last modified: | 2021-08-18 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The structure of Escherichia coli BtuF and binding to its cognate ATP binding cassette transporter Proc.Natl.Acad.Sci.USA, 99, 2002
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4FI3
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![BU of 4fi3 by Molmil](/molmil-images/mine/4fi3) | Structure of vitamin B12 transporter BtuCD-F in a nucleotide-bound state | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Vitamin B12 import ATP-binding protein BtuD, ... | Authors: | Korkhov, V.M, Mireku, S.A, Locher, K.P. | Deposit date: | 2012-06-07 | Release date: | 2012-09-19 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.466 Å) | Cite: | Structure of AMP-PNP-bound vitamin B12 transporter BtuCD-F. Nature, 490, 2012
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2QI9
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![BU of 2qi9 by Molmil](/molmil-images/mine/2qi9) | ABC-transporter BtuCD in complex with its periplasmic binding protein BtuF | Descriptor: | DI(HYDROXYETHYL)ETHER, PENTAETHYLENE GLYCOL, PHOSPHATE ION, ... | Authors: | Hvorup, R.N, Goetz, B.A, Niederer, M, Hollenstein, K, Perozo, E, Locher, K.P. | Deposit date: | 2007-07-03 | Release date: | 2007-08-14 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Asymmetry in the structure of the ABC transporter-binding protein complex BtuCD-BtuF. Science, 317, 2007
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6QEX
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![BU of 6qex by Molmil](/molmil-images/mine/6qex) | |
3CFZ
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![BU of 3cfz by Molmil](/molmil-images/mine/3cfz) | |
3CG1
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![BU of 3cg1 by Molmil](/molmil-images/mine/3cg1) | |
3RCE
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![BU of 3rce by Molmil](/molmil-images/mine/3rce) | Bacterial oligosaccharyltransferase PglB | Descriptor: | MAGNESIUM ION, Oligosaccharide transferase to N-glycosylate proteins, Substrate Mimic Peptide | Authors: | Lizak, C, Gerber, S, Numao, S, Aebi, M, Locher, K.P. | Deposit date: | 2011-03-31 | Release date: | 2011-06-15 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | X-ray structure of a bacterial oligosaccharyltransferase. Nature, 474, 2011
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3NU1
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![BU of 3nu1 by Molmil](/molmil-images/mine/3nu1) | Structure of holo form of a periplasmic heme binding protein | Descriptor: | Hemin-binding periplasmic protein, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Mattle, D, Goetz, B.A, Woo, J.S, Locher, K.P. | Deposit date: | 2010-07-06 | Release date: | 2010-10-13 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Two stacked heme molecules in the binding pocket of the periplasmic heme-binding protein HmuT from Yersinia pestis. J.Mol.Biol., 404, 2010
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3MD9
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![BU of 3md9 by Molmil](/molmil-images/mine/3md9) | Structure of apo form of a periplasmic heme binding protein | Descriptor: | BROMIDE ION, GLYCEROL, Hemin-binding periplasmic protein hmuT, ... | Authors: | Mattle, D, Goetz, B.A, Locher, K.P. | Deposit date: | 2010-03-30 | Release date: | 2010-09-15 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Two stacked heme molecules in the binding pocket of the periplasmic heme-binding protein HmuT from Yersinia pestis. J.Mol.Biol., 404, 2010
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4G1U
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![BU of 4g1u by Molmil](/molmil-images/mine/4g1u) | X-ray structure of the bacterial heme transporter HmuUV from Yersinia pestis | Descriptor: | Hemin import ATP-binding protein HmuV, Hemin transport system permease protein hmuU, PHOSPHATE ION | Authors: | Woo, J.-S, Goetz, B.A, Zeltina, A, Locher, K.P. | Deposit date: | 2012-07-11 | Release date: | 2012-12-19 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.008 Å) | Cite: | X-ray structure of the Yersinia pestis heme transporter HmuUV. Nat.Struct.Mol.Biol., 19, 2012
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4R9U
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![BU of 4r9u by Molmil](/molmil-images/mine/4r9u) | Structure of vitamin B12 transporter BtuCD in a nucleotide-bound outward facing state | Descriptor: | LAURYL DIMETHYLAMINE-N-OXIDE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Korkhov, V.M, Mireku, S.A, Veprintsev, D.B, Locher, K.P. | Deposit date: | 2014-09-08 | Release date: | 2014-11-19 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.785 Å) | Cite: | Structure of AMP-PNP-bound BtuCD and mechanism of ATP-powered vitamin B12 transport by BtuCD-F. Nat.Struct.Mol.Biol., 21, 2014
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7QBG
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![BU of 7qbg by Molmil](/molmil-images/mine/7qbg) | TC:CD320 in complex with nanobody TC-Nb4 | Descriptor: | Anti-TC:CD320 nanobody TC-Nb4, CALCIUM ION, CD320 antigen, ... | Authors: | Bloch, J.S, Locher, K.P. | Deposit date: | 2021-11-19 | Release date: | 2022-03-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.69 Å) | Cite: | Generation of nanobodies targeting the human, transcobalamin-mediated vitamin B 12 uptake route. Faseb J., 36, 2022
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7QBD
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![BU of 7qbd by Molmil](/molmil-images/mine/7qbd) | TC:CD320 in complex with nanobody TC-Nb26 | Descriptor: | Antitranscobalamin-nanobody TC-Nb26, CALCIUM ION, CD320 antigen, ... | Authors: | Bloch, J.S, Locher, K.P. | Deposit date: | 2021-11-19 | Release date: | 2022-03-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (4.18 Å) | Cite: | Generation of nanobodies targeting the human, transcobalamin-mediated vitamin B 12 uptake route. Faseb J., 36, 2022
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7QBF
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![BU of 7qbf by Molmil](/molmil-images/mine/7qbf) | TC:CD320 in complex with nanobody TC-Nb34 | Descriptor: | 1,2-ETHANEDIOL, Anti-transcobalamin-2 nanobody TC-Nb34, CALCIUM ION, ... | Authors: | Bloch, J.S, Locher, K.P. | Deposit date: | 2021-11-19 | Release date: | 2022-03-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Generation of nanobodies targeting the human, transcobalamin-mediated vitamin B 12 uptake route. Faseb J., 36, 2022
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7QBE
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![BU of 7qbe by Molmil](/molmil-images/mine/7qbe) | TC:CD320 in complex with nanobody TC-Nb11 | Descriptor: | Anti-transcobalamin-2 nanobody TC-Nb11, CALCIUM ION, CD320 antigen, ... | Authors: | Bloch, J.S, Locher, K.P. | Deposit date: | 2021-11-19 | Release date: | 2022-03-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Generation of nanobodies targeting the human, transcobalamin-mediated vitamin B 12 uptake route. Faseb J., 36, 2022
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3CFX
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![BU of 3cfx by Molmil](/molmil-images/mine/3cfx) | Crystal structure of M. acetivorans periplasmic binding protein ModA/WtpA with bound tungstate | Descriptor: | GLYCEROL, MAGNESIUM ION, TUNGSTATE(VI)ION, ... | Authors: | Comellas-Bigler, M, Hollenstein, K, Locher, K.P. | Deposit date: | 2008-03-04 | Release date: | 2009-03-10 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Distorted octahedral coordination of tungstate in a subfamily of specific binding proteins. J.Biol.Inorg.Chem., 14, 2009
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3CG3
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![BU of 3cg3 by Molmil](/molmil-images/mine/3cg3) | |
7A69
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![BU of 7a69 by Molmil](/molmil-images/mine/7a69) | |