2OFA
 
 | | Crystal structure of apo AVR4 (R112L,C122S) | | 分子名称: | Avidin-related protein 4/5, FORMIC ACID | | 著者 | Livnah, O, Hayouka, R, Eisenberg-Domovich, Y. | | 登録日 | 2007-01-03 | | 公開日 | 2007-12-25 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Critical importance of loop conformation to avidin-enhanced hydrolysis of an active biotin ester.
Acta Crystallogr.,Sect.D, 64, 2008
|
|
2OF8
 | | Crystal structure of AVR4 (D39A/C122S)-BNA complex | | 分子名称: | 5-(2-OXO-HEXAHYDRO-THIENO[3,4-D]IMIDAZOL-6-YL)-PENTANOIC ACID (4-NITRO-PHENYL)-AMIDE, Avidin-related protein 4/5, FORMIC ACID | | 著者 | Livnah, O, Hayouka, R, Eisenberg-Domovich, Y. | | 登録日 | 2007-01-03 | | 公開日 | 2007-12-25 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | | 主引用文献 | Critical importance of loop conformation to avidin-enhanced hydrolysis of an active biotin ester.
Acta Crystallogr.,Sect.D, 64, 2008
|
|
2OFB
 | | Crystal structure of AVR4 (R112L/C122S)-BNA complex | | 分子名称: | 5-(2-OXO-HEXAHYDRO-THIENO[3,4-D]IMIDAZOL-6-YL)-PENTANOIC ACID (4-NITRO-PHENYL)-AMIDE, Avidin-related protein 4/5, FORMIC ACID | | 著者 | Livnah, O, Hayouka, R, Eisenberg-Domovich, Y. | | 登録日 | 2007-01-03 | | 公開日 | 2007-12-25 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.16 Å) | | 主引用文献 | Critical importance of loop conformation to avidin-enhanced hydrolysis of an active biotin ester.
Acta Crystallogr.,Sect.D, 64, 2008
|
|
2FHL
 | | avidin related protein (AVR4)-BNA complex | | 分子名称: | 5-(2-OXO-HEXAHYDRO-THIENO[3,4-D]IMIDAZOL-6-YL)-PENTANOIC ACID (4-NITRO-PHENYL)-AMIDE, Avidin-related protein 4/5, FORMIC ACID | | 著者 | Livnah, O, Prizant, M. | | 登録日 | 2005-12-26 | | 公開日 | 2006-03-21 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | | 主引用文献 | Factors dictating the pseudocatalytic efficiency of avidins
J.Mol.Biol., 358, 2006
|
|
2FHN
 | |
7O9Y
 | |
7OA0
 | | Crystal structure of di-phosphorylated human CLK1 in complex with 5-(6,7-dichloro-1H-indol-3-yl)pyrimidin-4-amine | | 分子名称: | 5-[6,7-bis(chloranyl)-1-methyl-indol-3-yl]pyrimidin-4-amine, Dual specificity protein kinase CLK1 | | 著者 | Livnah, O, Domovich, Y, Bracher, F, Aiger, C. | | 登録日 | 2021-04-18 | | 公開日 | 2022-05-04 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Development of novel CLK1 inhibitors as potential drugs for treatment of Chikungunya virus infections
To Be Published
|
|
3OEF
 | |
3ODY
 | | Crystal structure of p38alpha Y323Q active mutant | | 分子名称: | Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside | | 著者 | Livnah, O, Tzarum, N. | | 登録日 | 2010-08-12 | | 公開日 | 2011-01-12 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Active mutants of the TCR-mediated p38alpha alternative activation site show changes in the phosphorylation lip and DEF site formation.
J.Mol.Biol., 405, 2011
|
|
3ODZ
 | | Crystal structure of P38alpha Y323R active mutant | | 分子名称: | Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside | | 著者 | Livnah, O, Tzarum, N. | | 登録日 | 2010-08-12 | | 公開日 | 2011-01-12 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Active mutants of the TCR-mediated p38alpha alternative activation site show changes in the phosphorylation lip and DEF site formation.
J.Mol.Biol., 405, 2011
|
|
3R63
 | |
4E6A
 | | p38a-PIA23 complex | | 分子名称: | (2S)-2-methoxy-3-(octadecyloxy)propyl (1R,2R,3R,4S,6S)-2,3,4-trihydroxy-6-(2-methylpropoxy)cyclohexyl hydrogen (S)-phosphate, Mitogen-activated protein kinase 14 | | 著者 | Livnah, O, Tzarum, N, Eisenberg-Domovich, Y. | | 登録日 | 2012-03-15 | | 公開日 | 2012-10-31 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Lipid Molecules Induce p38 alpha Activation via a Novel Molecular Switch.
J.Mol.Biol., 424, 2012
|
|
6R8J
 | |
6RFP
 | | ERK2 MAP kinase with mutations at Helix-G | | 分子名称: | Mitogen-activated protein kinase 1 | | 著者 | Livnah, O, Eitan-Wexler, M. | | 登録日 | 2019-04-16 | | 公開日 | 2020-05-13 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | The bacterial metalloprotease NleD selectively cleaves mitogen-activated protein kinases that have high flexibility in their activation loop.
J.Biol.Chem., 295, 2020
|
|
6RFO
 | | ERK2 MAP kinase with the activation loop of p38alpha | | 分子名称: | Mitogen-activated protein kinase 1,Mitogen-activated protein kinase 14,Mitogen-activated protein kinase 1 | | 著者 | Livnah, O, Eitan-Wexler, M. | | 登録日 | 2019-04-15 | | 公開日 | 2020-05-27 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The bacterial metalloprotease NleD selectively cleaves mitogen-activated protein kinases that have high flexibility in their activation loop.
J.Biol.Chem., 295, 2020
|
|
4GEO
 | | P38a MAP kinase DEF-pocket penta mutant (M194A, L195A, H228A, I229A, Y258A) | | 分子名称: | Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside | | 著者 | Livnah, O, Tzarum, N. | | 登録日 | 2012-08-02 | | 公開日 | 2013-05-22 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | | 主引用文献 | P38a MAP kinase DEF-pocket penta mutant (M194A, L195A, H228A, I229A, Y258A)
To be Published
|
|
4GGZ
 | |
6R6E
 | |
6R3D
 | |
6R6X
 | |
4GGT
 | |
4E6C
 | | p38a-perifosine Complex | | 分子名称: | (1,1-dimethylpiperidin-1-ium-4-yl) octadecyl hydrogen phosphate, Mitogen-activated protein kinase 14 | | 著者 | Livnah, O, Tzarum, N, Eisenberg-Domovich, Y. | | 登録日 | 2012-03-15 | | 公開日 | 2012-10-31 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | | 主引用文献 | Lipid Molecules Induce p38 alpha Activation via a Novel Molecular Switch.
J.Mol.Biol., 424, 2012
|
|
4E8A
 | | The crystal structure of p38a MAP kinase in complex with PIA24 | | 分子名称: | (1R,2S,3R,4S,6S)-6-(cyclohexylmethoxy)-2,3,4-trihydroxycyclohexyl (2R)-2-methoxy-3-(octadecyloxy)propyl hydrogen (S)-phosphate, Mitogen-activated protein kinase 14 | | 著者 | Livnah, O, Tzarum, N, Eisenberg-Domovich, Y. | | 登録日 | 2012-03-20 | | 公開日 | 2012-10-31 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Lipid Molecules Induce p38 alpha Activation via a Novel Molecular Switch.
J.Mol.Biol., 424, 2012
|
|
4GGR
 | |
4E5A
 | |
