6RFP

ERK2 MAP kinase with mutations at Helix-G

Summary for 6RFP

Entry DOI	10.2210/pdb6rfp/pdb
Descriptor	Mitogen-activated protein kinase 1 (2 entities in total)
Functional Keywords	nled, effectors, t3ss, map kinase, phosphorylation, transferase
Biological source	Rattus norvegicus (Rat)
Total number of polymer chains	1
Total formula weight	43425.74
Authors	Livnah, O.,Eitan-Wexler, M. (deposition date: 2019-04-16, release date: 2020-05-13, Last modification date: 2024-01-24)
Primary citation	Gur-Arie, L.,Eitan-Wexler, M.,Weinberger, N.,Rosenshine, I.,Livnah, O. The bacterial metalloprotease NleD selectively cleaves mitogen-activated protein kinases that have high flexibility in their activation loop. J.Biol.Chem., 295:9409-9420, 2020 Cited by PubMed: 32404367 DOI: 10.1074/jbc.RA120.013590 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.74 Å)

Structure validation