7LW2
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7MG0
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7F9W
| CD25 in complex with Fab | Descriptor: | Heavy chain of Fab, Interleukin-2 receptor subunit alpha, Light chain of Fab | Authors: | Liu, C. | Deposit date: | 2021-07-05 | Release date: | 2022-01-12 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Two novel human anti-CD25 antibodies with antitumor activity inversely related to their affinity and in vitro activity. Sci Rep, 11, 2021
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7N0C
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7N0D
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7N0B
| Cryo-EM structure of SARS-CoV-2 nsp10-nsp14 (WT)-RNA complex | Descriptor: | CALCIUM ION, Non-structural protein 10, Proofreading exoribonuclease, ... | Authors: | Liu, C, Yang, Y. | Deposit date: | 2021-05-25 | Release date: | 2021-07-28 | Last modified: | 2021-09-22 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural basis of mismatch recognition by a SARS-CoV-2 proofreading enzyme. Science, 373, 2021
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4WXO
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4WXW
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8SM9
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6PQY
| Cryo-EM structure of HzTransib/TIR DNA transposon end complex (TEC) | Descriptor: | DNA (5'-D(P*CP*AP*CP*GP*GP*TP*GP*GP*AP*TP*CP*GP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*CP*GP*AP*TP*CP*CP*AP*CP*CP*GP*TP*G)-3'), Putative DNA-mediated transposase | Authors: | Liu, C, Yang, Y, Schatz, D.G. | Deposit date: | 2019-07-10 | Release date: | 2019-10-09 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structures of a RAG-like transposase during cut-and-paste transposition. Nature, 575, 2019
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6PR5
| Cryo-EM structure of HzTransib strand transfer complex (STC) | Descriptor: | DNA (30-MER), DNA (39-MER), DNA (5'-D(*GP*AP*TP*CP*TP*GP*GP*CP*CP*TP*AP*GP*AP*TP*CP*TP*CP*A)-3'), ... | Authors: | Liu, C, Yang, Y, Schatz, D.G. | Deposit date: | 2019-07-10 | Release date: | 2019-10-09 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structures of a RAG-like transposase during cut-and-paste transposition. Nature, 575, 2019
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8DMM
| Structure of the vanadate-trapped MsbA bound to KDL | Descriptor: | (2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-[(2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-carboxy-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-5-[[(3~{R})-3-dodecanoyloxytetradecanoyl]amino]-6-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-3-oxidanyl-5-[[(3~{R})-3-oxidanyltetradecanoyl]amino]-4-[(3~{R})-3-oxidanyltetradecanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-4-[(3~{R})-3-tetradecanoyloxytetradecanoyl]oxy-oxan-2-yl]methoxy]-5-oxidanyl-oxan-4-yl]oxy-4,5-bis(oxidanyl)oxane-2-carboxylic acid, ADP ORTHOVANADATE, ATP-binding transport protein MsbA | Authors: | Liu, C, Lyu, J, Laganowsky, A.D, Zhao, M. | Deposit date: | 2022-07-08 | Release date: | 2022-12-14 | Method: | ELECTRON MICROSCOPY (3.47 Å) | Cite: | Structural basis for lipid and copper regulation of the ABC transporter MsbA. Nat Commun, 13, 2022
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8DMO
| Structure of open, inward-facing MsbA from E. coli | Descriptor: | ATP-binding transport protein MsbA | Authors: | Liu, C, Lyu, J, Laganowsky, A.D, Zhao, M. | Deposit date: | 2022-07-08 | Release date: | 2022-12-14 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural basis for lipid and copper regulation of the ABC transporter MsbA. Nat Commun, 13, 2022
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6PQN
| Crystal structure of HzTransib transposase | Descriptor: | GLYCEROL, PHOSPHATE ION, Putative DNA-mediated transposase, ... | Authors: | Liu, C, Yang, Y, Schatz, D.G. | Deposit date: | 2019-07-09 | Release date: | 2019-10-09 | Last modified: | 2019-12-18 | Method: | X-RAY DIFFRACTION (3.01 Å) | Cite: | Structures of a RAG-like transposase during cut-and-paste transposition. Nature, 575, 2019
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6PQU
| Cryo-EM structure of HzTransib/nicked TIR substrate DNA pre-reaction complex (PRC) | Descriptor: | DNA (5'-D(P*AP*TP*CP*TP*GP*GP*CP*CP*TP*AP*GP*AP*TP*CP*T)-3'), DNA (5'-D(P*CP*AP*CP*GP*GP*TP*GP*GP*AP*TP*CP*GP*AP*AP*AP*A)-3'), DNA-mediated transposase, ... | Authors: | Liu, C, Yang, Y, Schatz, D.G. | Deposit date: | 2019-07-10 | Release date: | 2019-10-09 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structures of a RAG-like transposase during cut-and-paste transposition. Nature, 575, 2019
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6PQX
| Cryo-EM structure of HzTransib/nicked TIR substrate DNA hairpin forming complex (HFC) | Descriptor: | CALCIUM ION, DNA (5'-D(P*CP*AP*CP*GP*GP*TP*GP*GP*AP*TP*CP*GP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*CP*TP*GP*GP*CP*CP*TP*AP*GP*AP*TP*CP*T)-3'), ... | Authors: | Liu, C, Yang, Y, Schatz, D.G. | Deposit date: | 2019-07-10 | Release date: | 2019-10-09 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Structures of a RAG-like transposase during cut-and-paste transposition. Nature, 575, 2019
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6PQR
| Cryo-EM structure of HzTransib/intact TIR substrate DNA pre-reaction complex (PRC) | Descriptor: | DNA (5'-D(*CP*TP*AP*GP*AP*TP*CP*TP*CP*AP*CP*GP*GP*TP*GP*GP*AP*TP*CP*GP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*CP*GP*AP*TP*CP*CP*AP*CP*CP*GP*TP*GP*AP*GP*AP*TP*CP*TP*AP*G)-3'), DNA-mediated transposase, ... | Authors: | Liu, C, Yang, Y, Schatz, D.G. | Deposit date: | 2019-07-09 | Release date: | 2019-10-09 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structures of a RAG-like transposase during cut-and-paste transposition. Nature, 575, 2019
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7E23
| SARS-CoV-2 spike in complex with the CA521 neutralizing antibody Fab (focused refinement on Fab-RBD) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CA521 Heavy Chain, CA521 Light Chain, ... | Authors: | Liu, C, Song, D, Dou, C. | Deposit date: | 2021-02-04 | Release date: | 2021-05-05 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure and function analysis of a potent human neutralizing antibody CA521 FALA against SARS-CoV-2. Commun Biol, 4, 2021
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8SM8
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8SMA
| SfbO with di-Manganese cofactor | Descriptor: | Amidohydrolase family protein, MANGANESE (II) ION, SULFATE ION | Authors: | Liu, C, Rittle, J. | Deposit date: | 2023-04-25 | Release date: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Bioinformatic Discovery of a Cambialistic Monooxygenase. J.Am.Chem.Soc., 146, 2024
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8SM7
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8SM6
| Aerobic, Diiron(III)-metalated SfbO | Descriptor: | Amidohydrolase family protein, FE (III) ION, SULFATE ION | Authors: | Liu, C, Powell, M.M, Rittle, J. | Deposit date: | 2023-04-25 | Release date: | 2024-01-24 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.39 Å) | Cite: | Bioinformatic Discovery of a Cambialistic Monooxygenase. J.Am.Chem.Soc., 146, 2024
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8TXR
| E. coli ExoVII(H238A) | Descriptor: | Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease 7 small subunit | Authors: | Liu, C, Berger, J.M. | Deposit date: | 2023-08-24 | Release date: | 2024-01-31 | Last modified: | 2024-02-07 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure of Escherichia coli exonuclease VII. Proc.Natl.Acad.Sci.USA, 121, 2024
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7JRE
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2LE8
| The protein complex for DNA replication | Descriptor: | DNA replication factor Cdt1, DNA replication licensing factor MCM6 | Authors: | Liu, C, Wei, Z, Zhu, G. | Deposit date: | 2011-06-14 | Release date: | 2012-12-19 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Structural insights into the Cdt1-mediated MCM2-7 chromatin loading Nucleic Acids Res., 40, 2012
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