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PDB: 476 件

8IRZ
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Carbon Sulfoxide lyase
分子名称: PYRIDOXAL-5'-PHOSPHATE, Probable hercynylcysteine sulfoxide lyase
著者Gong, W.M, Wei, L.L, Liu, L.
登録日2023-03-20
公開日2024-03-06
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献Structure of mycobacterial ergothioneine-biosynthesis C-S lyase EgtE.
J.Biol.Chem., 300, 2024
8IS0
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Carbon Sulfoxide lyase - Y106F
分子名称: 2-AMINO-ACRYLIC ACID, PYRIDOXAL-5'-PHOSPHATE, Probable hercynylcysteine sulfoxide lyase
著者Gong, W.M, Wei, L.L, Liu, L.
登録日2023-03-20
公開日2024-03-06
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.02 Å)
主引用文献Structure of mycobacterial ergothioneine-biosynthesis C-S lyase EgtE.
J.Biol.Chem., 300, 2024
4ZDS
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Crystal Structure of core DNA binding domain of Arabidopsis Thaliana Transcription Factor Ethylene-Insensitive 3
分子名称: Protein ETHYLENE INSENSITIVE 3
著者Song, J, Zhu, C, Zhang, X, Wen, X, Liu, L, Peng, J, Guo, H, Yi, C.
登録日2015-04-18
公開日2015-09-23
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Biochemical and Structural Insights into the Mechanism of DNA Recognition by Arabidopsis ETHYLENE INSENSITIVE3.
Plos One, 10, 2015
5GXU
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Cystal structure of Arabidopsis ATR2
分子名称: FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADPH--cytochrome P450 reductase 2
著者Niu, G, Liu, L.
登録日2016-09-20
公開日2017-01-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the Arabidopsis thaliana NADPH-cytochrome P450 reductase 2 (ATR2) provides insight into its function
FEBS J., 284, 2017
4ZHJ
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Crystal Structure of the Catalytic Subunit of Magnesium Chelatase
分子名称: Mg-chelatase subunit ChlH
著者Chen, X, Pu, H, Fang, Y, Liu, L.
登録日2015-04-25
公開日2015-08-26
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.502 Å)
主引用文献Crystal structure of the catalytic subunit of magnesium chelatase
Nat.Plants, 1, 2015
4YVQ
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Crystal Structure of FLU-TPR in Complex with the C-terminal Region of GluTR
分子名称: Glutamyl-tRNA reductase 1, chloroplastic, Protein FLUORESCENT IN BLUE LIGHT
著者Zhang, M, Zhang, F, Liu, L.
登録日2015-03-20
公開日2015-06-10
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.401 Å)
主引用文献The Non-canonical Tetratricopeptide Repeat (TPR) Domain of Fluorescent (FLU) Mediates Complex Formation with Glutamyl-tRNA Reductase.
J.Biol.Chem., 290, 2015
5HH1
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Crystal structure of human Naa60 mutant - F34A in complex with CoA
分子名称: COENZYME A, N-alpha-acetyltransferase 60
著者Chen, J.Y, Liu, L, Yun, C.H.
登録日2016-01-09
公開日2016-09-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.803 Å)
主引用文献Structure and function of human Naa60 (NatF), a Golgi-localized bi-functional acetyltransferase
Sci Rep, 6, 2016
5HGZ
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Crystal structure of human Naa60 in complex with acetyl-CoA
分子名称: ACETYL COENZYME *A, MALONIC ACID, N-alpha-acetyltransferase 60
著者Chen, J.Y, Liu, L, Yun, C.H.
登録日2016-01-09
公開日2016-09-14
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.383 Å)
主引用文献Structure and function of human Naa60 (NatF), a Golgi-localized bi-functional acetyltransferase
Sci Rep, 6, 2016
4YVO
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Crystal Structure of the TPR Domain of Arabidopsis FLU (FLU-TPR)
分子名称: Protein FLUORESCENT IN BLUE LIGHT, chloroplastic
著者Zhang, M, Zhang, F, Liu, L.
登録日2015-03-20
公開日2015-06-10
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献The Non-canonical Tetratricopeptide Repeat (TPR) Domain of Fluorescent (FLU) Mediates Complex Formation with Glutamyl-tRNA Reductase.
J.Biol.Chem., 290, 2015
5B6L
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Structure of Deg protease HhoA from Synechocystis sp. PCC 6803
分子名称: Putative serine protease HhoA, SODIUM ION, UNK-UNK-UNK-UNK-TRP, ...
著者Dong, W, Wang, J, Liu, L.
登録日2016-05-30
公開日2016-09-21
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.801 Å)
主引用文献Crystal structure of the zinc-bound HhoA protease from Synechocystis sp. PCC 6803
Febs Lett., 590, 2016
6KFI
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NMR solution structure of the 1:1 complex of Tel26 G-quadruplex and a tripodal cationic fluorescent probe NBTE
分子名称: 4,4',4''-(nitrilotris(benzene-4,1-diyl))tris(1-ethylpyridin-1-ium) iodide, G-quadruplex DNA (26-MER)
著者Liu, W, Liu, L.Y, Mao, Z.W.
登録日2019-07-07
公開日2020-07-08
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Quantitative Detection of G-Quadruplex DNA in Live Cells Based on Photon Counts and Complex Structure Discrimination.
Angew.Chem.Int.Ed.Engl., 59, 2020
6KFJ
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NMR solution structure of the 1:1 complex of wtTel26 G-quadruplex and a tripodal cationic fluorescent probe NBTE
分子名称: 4,4',4''-(nitrilotris(benzene-4,1-diyl))tris(1-ethylpyridin-1-ium) iodide, G-quadruplex DNA wtTel26
著者Liu, W, Liu, L.Y, Mao, Z.W.
登録日2019-07-07
公開日2020-07-01
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Quantitative Detection of G-Quadruplex DNA in Live Cells Based on Photon Counts and Complex Structure Discrimination.
Angew.Chem.Int.Ed.Engl., 59, 2020
5YEI
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Mechanistic insight into the regulation of Pseudomonas aeruginosa aspartate kinase
分子名称: Aspartokinase, GLYCEROL, LYSINE, ...
著者Li, C, Yang, M, Liu, L, Peng, C, Li, T, He, L, Song, Y, Zhu, Y, Bao, R.
登録日2017-09-17
公開日2018-08-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献Mechanistic insights into the allosteric regulation of Pseudomonas aeruginosa aspartate kinase.
Biochem.J., 475, 2018
8KAJ
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Crystal structure of SpyCas9-crRNA-tracrRNA complex bound to 16nt target DNA
分子名称: CRISPR-associated endonuclease Cas9/Csn1, DNA (5'-D(*CP*AP*AP*TP*AP*CP*CP*TP*TP*TP*TP*AP*TP*CP*CP*AP*TP*AP*AP*AP*TP*TP*CP*G)-3'), DNA (5'-D(*TP*TP*TP*AP*GP*GP*TP*AP*TP*TP*G)-3'), ...
著者Chen, Y, Chen, J, Liu, L.
登録日2023-08-03
公開日2024-06-05
最終更新日2024-06-12
実験手法X-RAY DIFFRACTION (3.42 Å)
主引用文献Trans-nuclease activity of Cas9 activated by DNA or RNA target binding.
Nat.Biotechnol., 2024
8KAM
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Crystal structure of SpyCas9 in complex with sgRNA and 16nt target DNA
分子名称: CRISPR-associated endonuclease Cas9/Csn1, DNA (5'-D(*CP*AP*AP*TP*AP*CP*CP*TP*CP*TP*TP*CP*AP*AP*TP*TP*AP*GP*AP*AP*CP*AP*CP*G)-3'), DNA (5'-D(*TP*TP*TP*AP*GP*GP*TP*AP*TP*TP*G)-3'), ...
著者Chen, Y, Chen, J, Liu, L.
登録日2023-08-03
公開日2024-06-05
最終更新日2024-06-12
実験手法X-RAY DIFFRACTION (3.91 Å)
主引用文献Trans-nuclease activity of Cas9 activated by DNA or RNA target binding.
Nat.Biotechnol., 2024
8KAG
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Crystal structure of SpyCas9 in complex with sgRNA and target RNA
分子名称: CRISPR-associated endonuclease Cas9/Csn1, RNA (5'-R(*CP*CP*AP*CP*UP*UP*CP*AP*AP*UP*UP*AP*GP*AP*AP*CP*AP*CP*GP*GP*AP*CP*C)-3'), RNA (98-MER)
著者Chen, Y, Chen, J, Liu, L.
登録日2023-08-03
公開日2024-06-05
最終更新日2024-06-12
実験手法X-RAY DIFFRACTION (3.88 Å)
主引用文献Trans-nuclease activity of Cas9 activated by DNA or RNA target binding.
Nat.Biotechnol., 2024
8KAH
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Crystal structure of SpyCas9-crRNA-tracrRNA complex bound to 18nt target DNA
分子名称: CRISPR-associated endonuclease Cas9/Csn1, DNA (26-MER), DNA (5'-D(*TP*TP*TP*AP*GP*GP*TP*AP*TP*TP*G)-3'), ...
著者Chen, Y, Chen, J, Liu, L.
登録日2023-08-03
公開日2024-06-05
最終更新日2024-06-12
実験手法X-RAY DIFFRACTION (3.36 Å)
主引用文献Trans-nuclease activity of Cas9 activated by DNA or RNA target binding.
Nat.Biotechnol., 2024
6BTA
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BU of 6bta by Molmil
CypA Mutant - S99T C115S
分子名称: Peptidyl-prolyl cis-trans isomerase A
著者Fraser, J.S, Kenner, L.R, Liu, L.
登録日2017-12-06
公開日2018-04-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Rescue of conformational dynamics in enzyme catalysis by directed evolution.
Nat Commun, 9, 2018
4MRO
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BU of 4mro by Molmil
Human GKRP bound to AMG-5980 and S6P
分子名称: 2-(4-{4-[(6-aminopyridin-3-yl)sulfonyl]piperazin-1-yl}phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol, D-SORBITOL-6-PHOSPHATE, GLYCEROL, ...
著者St Jean, D.J, Ashton, K.S, Bartberger, M.D, Chen, J, Chmait, S, Cupples, R, Galbreath, E, Helmering, J, Jordan, S.R, Liu, L, Kunz, K, Michelsen, K, Nishimura, N, Pennington, L.D, Poon, S.F, Sivits, G, Stec, M.M, Tamayo, N, Van, G, Yang, K, Norman, M.H, Fotsch, C, LLoyd, D.J, Hale, C.
登録日2013-09-17
公開日2014-05-07
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 2. Leveraging structure-based drug design to identify analogues with improved pharmacokinetic profiles.
J.Med.Chem., 57, 2014
5FW5
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Crystal structure of human G3BP1 in complex with Semliki Forest Virus nsP3-25 comprising two FGDF motives
分子名称: ACETATE ION, GLYCEROL, NON-STRUCTURAL PROTEIN 3, ...
著者Schulte, T, Liu, L, Panas, M.D, Thaa, B, Goette, B, Achour, A, McInerney, G.M.
登録日2016-02-12
公開日2016-07-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Combined structural, biochemical and cellular evidence demonstrates that both FGDF motifs in alphavirus nsP3 are required for efficient replication.
Open Biol, 6, 2016
4J4D
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BU of 4j4d by Molmil
Structure of P51G Cyanovirin-N swapped dimer in the P21212 space group
分子名称: Cyanovirin-N
著者Koharudin, L.M.I, Liu, L, Gronenborn, A.M.
登録日2013-02-06
公開日2013-04-03
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Different 3D domain-swapped oligomeric cyanovirin-N structures suggest trapped folding intermediates.
Proc.Natl.Acad.Sci.USA, 110, 2013
4J4C
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Structure of P51G Cyanovirin-N swapped dimer in the P3221 space group
分子名称: Cyanovirin-N
著者Koharudin, L.M.I, Liu, L, Gronenborn, A.M.
登録日2013-02-06
公開日2013-04-03
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Different 3D domain-swapped oligomeric cyanovirin-N structures suggest trapped folding intermediates.
Proc.Natl.Acad.Sci.USA, 110, 2013
7XCT
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Cryo-EM structure of Dot1L and H2BK34ub-H3K79Nle nucleosome 2:1 complex
分子名称: DNA (145-MER), Histone H2A, Histone H2B type 1-K, ...
著者Ai, H.S, Liu, A.J, Lou, Z.Y, Liu, L.
登録日2022-03-25
公開日2022-04-20
最終更新日2022-09-07
実験手法ELECTRON MICROSCOPY (2.72 Å)
主引用文献H2B Lys34 Ubiquitination Induces Nucleosome Distortion to Stimulate Dot1L Activity.
Nat.Chem.Biol., 18, 2022
7XCR
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Cryo-EM structure of Dot1L and H2BK34ub-H3K79Nle nucleosome 1:1 complex
分子名称: DNA (146-MER), Histone H2A, Histone H2B type 1-K, ...
著者Ai, H.S, Liu, A.J, Lou, Z.Y, Liu, L.
登録日2022-03-25
公開日2022-04-20
最終更新日2022-09-07
実験手法ELECTRON MICROSCOPY (2.57 Å)
主引用文献H2B Lys34 Ubiquitination Induces Nucleosome Distortion to Stimulate Dot1L Activity.
Nat.Chem.Biol., 18, 2022
7XD0
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cryo-EM structure of H2BK34ub nucleosome
分子名称: DNA (146-MER), Histone H2A, Histone H2B type 1-K, ...
著者Ai, H.S, Liu, A.J, Lou, Z.Y, Liu, L.
登録日2022-03-26
公開日2022-04-20
最終更新日2022-09-07
実験手法ELECTRON MICROSCOPY (3.48 Å)
主引用文献H2B Lys34 Ubiquitination Induces Nucleosome Distortion to Stimulate Dot1L Activity.
Nat.Chem.Biol., 18, 2022

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