4O9R
| Human Smoothened Receptor structure in complex with cyclopamine | Descriptor: | Cyclopamine, Smoothened homolog/Soluble cytochrome b562 chimeric protein | Authors: | Wang, C, Weierstall, U, James, D, White, T.A, Wang, D, Liu, W, Spence, J.C.H, Doak, R.B, Nelson, G, Fromme, P, Fromme, R, Grotjohann, I, Kupitz, C, Zatsepin, N.A, Liu, H, Basu, S, Wacker, D, Han, G.W, Katritch, V, Boutet, S, Messerschmidt, M, Willams, G.J, Koglin, J.E, Seibert, M.M, Klinker, M, Gati, C, Shoeman, R.L, Barty, A, Chapman, H.N, Kirian, R.A, Beyerlein, K.R, Stevens, R.C, Li, D, Shah, S.T.A, Howe, N, Caffrey, M, Cherezov, V, GPCR Network (GPCR) | Deposit date: | 2014-01-02 | Release date: | 2014-03-05 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.204 Å) | Cite: | Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography. Nat Commun, 5, 2014
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1AZV
| FAMILIAL ALS MUTANT G37R CUZNSOD (HUMAN) | Descriptor: | COPPER (II) ION, COPPER/ZINC SUPEROXIDE DISMUTASE, ZINC ION | Authors: | Hart, P.J, Liu, H, Pellegrini, M, Nersissian, A.M, Gralla, E.B, Valentine, J.S, Eisenberg, D. | Deposit date: | 1997-11-21 | Release date: | 1998-02-25 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Subunit asymmetry in the three-dimensional structure of a human CuZnSOD mutant found in familial amyotrophic lateral sclerosis. Protein Sci., 7, 1998
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8K37
| Structure of the bacteriophage lambda neck | Descriptor: | Head-tail connector protein FII, Tail tube protein, Tail tube terminator protein | Authors: | Xiao, H, Tan, L, Cheng, L.P, Liu, H.R. | Deposit date: | 2023-07-14 | Release date: | 2023-11-15 | Last modified: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure of the siphophage neck-Tail complex suggests that conserved tail tip proteins facilitate receptor binding and tail assembly. Plos Biol., 21, 2023
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8K38
| The structure of bacteriophage lambda portal-adaptor | Descriptor: | Head completion protein, Portal protein B | Authors: | Xiao, H, Tan, L, Cheng, L.P, Liu, H.R. | Deposit date: | 2023-07-14 | Release date: | 2023-11-15 | Last modified: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structure of the siphophage neck-Tail complex suggests that conserved tail tip proteins facilitate receptor binding and tail assembly. Plos Biol., 21, 2023
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2XU8
| Structure of Pa1645 | Descriptor: | PA1645, SULFATE ION | Authors: | Abdelli, W.B, Moynie, L, McMahon, S.A, Liu, H, Alphey, M.S, Naismith, J.H. | Deposit date: | 2010-10-15 | Release date: | 2010-12-29 | Last modified: | 2015-08-19 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | The Aeropath Project Targeting Pseudomonas Aeruginosa: Crystallographic Studies for Assessment of Potential Targets in Early-Stage Drug Discovery Acta Crystallogr.,Sect.F, 69, 2013
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5ZZ9
| Crystal structure of Homer2 EVH1/Drebrin PPXXF complex | Descriptor: | Homer protein homolog 2, Peptide from Drebrin | Authors: | Li, Z, Liu, H, Li, J, Liu, W, Zhang, M. | Deposit date: | 2018-05-31 | Release date: | 2018-12-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Homer Tetramer Promotes Actin Bundling Activity of Drebrin. Structure, 27, 2019
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5XR8
| Crystal structure of the human CB1 in complex with agonist AM841 | Descriptor: | (6~{a}~{R},9~{R},10~{a}~{R})-9-(hydroxymethyl)-3-(8-isothiocyanato-2-methyl-octan-2-yl)-6,6-dimethyl-6~{a},7,8,9,10,10~{a}-hexahydrobenzo[c]chromen-1-ol, CHOLESTEROL, Cannabinoid receptor 1,Flavodoxin,Cannabinoid receptor 1, ... | Authors: | Hua, T, Vemuri, K, Nikas, P.S, Laprairie, R.B, Wu, Y, Qu, L, Pu, M, Korde, A, Shan, J, Ho, J.H, Han, G.W, Ding, K, Li, X, Liu, H, Hanson, M.A, Zhao, S, Bohn, L.M, Makriyannis, A, Stevens, R.C, Liu, Z.J. | Deposit date: | 2017-06-07 | Release date: | 2017-07-12 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Crystal structures of agonist-bound human cannabinoid receptor CB1. Nature, 547, 2017
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8JAN
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8JAJ
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7JW8
| Crystal structure of SARS-CoV-2 3CL protease in complex with compound 4 in space group P1 | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3C-like proteinase, ethyl (4R)-4-[[(2S)-4-methyl-2-[[(2S,3R)-3-[(2-methylpropan-2-yl)oxy]-2-(phenylmethoxycarbonylamino)butanoyl]amino]pentanoyl]amino]-5-[(3S)-2-oxidanylidenepyrrolidin-3-yl]pentanoate | Authors: | Iketani, S, Forouhar, F, Liu, H, Hong, S.J, Lin, F.-Y, Nair, M.S, Zask, A, Xing, L, Stockwell, B.R, Chavez, A, Ho, D.D. | Deposit date: | 2020-08-25 | Release date: | 2021-03-10 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Lead compounds for the development of SARS-CoV-2 3CL protease inhibitors. Nat Commun, 12, 2021
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8H0Q
| Structure of the GRP14-27-GRPR-Gq complex | Descriptor: | CHOLESTEROL, G-alpha q, GRP, ... | Authors: | Li, C, Xu, Y, Liu, H, Cai, H, Xu, H.E, Yin, W. | Deposit date: | 2022-09-30 | Release date: | 2023-08-09 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Molecular recognition of itch-associated neuropeptides by bombesin receptors Cell Res., 33, 2023
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4DSK
| Crystal structure of fragment DNA polymerase I from Bacillus stearothermophilus with duplex DNA, PPi and Calcium | Descriptor: | CALCIUM ION, DNA (5'-D(*GP*GP*CP*TP*AP*CP*AP*GP*GP*AP*CP*TP*CP*G)-3'), DNA (5'-D(*TP*CP*AP*CP*GP*AP*GP*TP*CP*CP*TP*GP*TP*AP*GP*CP*C)-3'), ... | Authors: | Gan, J.H, Abdur, R, Liu, H.H, Sheng, J, Caton-Willians, J, Soares, A.S, Huang, Z. | Deposit date: | 2012-02-19 | Release date: | 2013-03-27 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Biochemical and structural insights into the fidelity of bacillus stearothermophilus DNA polymerase To be Published
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2XVO
| SSO1725, a protein involved in the CRISPR/Cas pathway | Descriptor: | BETA-MERCAPTOETHANOL, SSO1725, SULFATE ION | Authors: | Reeks, J, Liu, H, Naismith, J, White, M, McMahon, S. | Deposit date: | 2010-10-26 | Release date: | 2010-12-29 | Last modified: | 2014-02-05 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | Structure and Mechanism of the Cmr Complex for Crispr-Mediated Antiviral Immunity. Mol.Cell, 45, 2012
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4DSL
| Crystal structure of fragment DNA polymerase I from Bacillus stearothermophilus with duplex DNA and Calcium | Descriptor: | DNA (5'-D(*G*GP*CP*TP*AP*CP*AP*GP*GP*AP*CP*TP*C)-3'), DNA (5'-D(*TP*CP*AP*CP*GP*AP*GP*TP*CP*CP*TP*GP*TP*AP*GP*CP*C)-3'), DNA polymerase, ... | Authors: | Gan, J.H, Abdur, R, Liu, H.H, Sheng, J, Caton-Willians, J, Soares, A.S, Huang, Z. | Deposit date: | 2012-02-19 | Release date: | 2013-03-27 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Biochemical and structural insights into the fidelity of bacillus stearothermophilus DNA polymerase To be Published
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8K36
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3FFE
| Structure of Achromobactin Synthetase Protein D, (AcsD) | Descriptor: | AcsD | Authors: | McMahon, S.A, Liu, H, Carter, L, Oke, M, Johnson, K.A, Schmelz, S, Challis, G.L, White, M.F, Naismith, J.H, Scottish Structural Proteomics Facility (SSPF) | Deposit date: | 2008-12-03 | Release date: | 2009-02-03 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | AcsD catalyzes enantioselective citrate desymmetrization in siderophore biosynthesis Nat.Chem.Biol., 5, 2009
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3J6Q
| Identification of the active sites in the methyltransferases of a transcribing dsRNA virus | Descriptor: | S-ADENOSYL-L-HOMOCYSTEINE, Structural protein VP3 | Authors: | Zhu, B, Yang, C, Liu, H, Cheng, L, Song, F, Zeng, S, Huang, X, Ji, G, Zhu, P. | Deposit date: | 2014-03-20 | Release date: | 2014-10-08 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Identification of the active sites in the methyltransferases of a transcribing dsRNA virus. J.Mol.Biol., 426, 2014
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4DWI
| Crystal structure of fragment DNA polymerase I from Bacillus stearothermophilus with self complementary DNA, Se-dGTP and Calcium | Descriptor: | 9-METHYLGUANINE, CALCIUM ION, DNA (5'-D(*AP*CP*TP*GP*GP*AP*TP*CP*CP*A)-3'), ... | Authors: | Gan, J.H, Abdur, R, Liu, H.H, Sheng, J, Caton-Willians, J, Soares, A.S, Huang, Z. | Deposit date: | 2012-02-24 | Release date: | 2013-03-27 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Biochemical and structural insights into the fidelity of bacillus stearothermophilus DNA polymerase To be Published
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7JVB
| Crystal structure of the SARS-CoV-2 spike receptor-binding domain (RBD) with nanobody Nb20 | Descriptor: | CACODYLATE ION, Nanobody Nb20, Spike protein S1 | Authors: | Xiang, Y, Xiao, Z, Liu, H, Sang, Z, Schneidman-Duhovny, D, Zhang, C, Shi, Y. | Deposit date: | 2020-08-20 | Release date: | 2020-12-02 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.287 Å) | Cite: | Versatile and multivalent nanobodies efficiently neutralize SARS-CoV-2. Science, 370, 2020
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2HK8
| Crystal structure of shikimate dehydrogenase from aquifex aeolicus at 2.35 angstrom resolution | Descriptor: | Shikimate dehydrogenase | Authors: | Gan, J.H, Prabakaran, P, Gu, Y.J, Andrykovitch, M, Li, Y, Liu, H.H, Yan, H, Ji, X. | Deposit date: | 2006-07-03 | Release date: | 2007-06-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural and biochemical analyses of shikimate dehydrogenase AroE from Aquifex aeolicus: implications for the catalytic mechanism. Biochemistry, 46, 2007
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2HK9
| Crystal structure of shikimate dehydrogenase from aquifex aeolicus in complex with shikimate and NADP+ at 2.2 angstrom resolution | Descriptor: | (3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC ACID, 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Gan, J.H, Prabakaran, P, Gu, Y.J, Andrykovitch, M, Li, Y, Liu, H.H, Yan, H, Ji, X. | Deposit date: | 2006-07-03 | Release date: | 2007-06-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural and biochemical analyses of shikimate dehydrogenase AroE from Aquifex aeolicus: implications for the catalytic mechanism. Biochemistry, 46, 2007
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2HK7
| Crystal structure of shikimate dehydrogenase from aquifex aeolicus in complex with mercury at 2.5 angstrom resolution | Descriptor: | MERCURY (II) ION, Shikimate dehydrogenase | Authors: | Gan, J.H, Prabakaran, P, Gu, Y.J, Andrykovitch, M, Li, Y, Liu, H.H, Yan, H, Ji, X. | Deposit date: | 2006-07-03 | Release date: | 2007-06-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural and biochemical analyses of shikimate dehydrogenase AroE from Aquifex aeolicus: implications for the catalytic mechanism. Biochemistry, 46, 2007
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4DSI
| Crystal structure of fragment DNA polymerase I from Bacillus stearothermophilus with duplex DNA, Se-dGTP and Calcium | Descriptor: | 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, CALCIUM ION, DNA, ... | Authors: | Gan, J.H, Abdur, R, Liu, H.H, Sheng, J, Caton-Willians, J, Soares, A.S, Huang, Z. | Deposit date: | 2012-02-19 | Release date: | 2013-03-27 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Biochemical and structural insights into the fidelity of bacillus stearothermophilus DNA polymerase To be Published
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4DSJ
| Crystal structure of fragment DNA polymerase I from Bacillus stearothermophilus with duplex DNA, dGTP and Calcium | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA, ... | Authors: | Gan, J.H, Abdur, R, Liu, H.H, Sheng, J, Caton-Willians, J, Soares, A.S, Huang, Z. | Deposit date: | 2012-02-19 | Release date: | 2013-03-27 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.86 Å) | Cite: | Biochemical and structural insights into the fidelity of bacillus stearothermophilus DNA polymerase To be Published
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3B3Q
| Crystal structure of a synaptic adhesion complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Chen, X, Liu, H, Shim, A, Focia, P, He, X. | Deposit date: | 2007-10-22 | Release date: | 2008-01-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis for synaptic adhesion mediated by neuroligin-neurexin interactions. Nat.Struct.Mol.Biol., 15, 2008
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