4AVY
The AEROPATH project and Pseudomonas aeruginosa high-throughput crystallographic studies for assessment of potential targets in early stage drug discovery.
Summary for 4AVY
Entry DOI | 10.2210/pdb4avy/pdb |
Descriptor | PROBABLE SHORT-CHAIN DEHYDROGENASE (2 entities in total) |
Functional Keywords | oxidoreductase, infectious disease, structure-based inhibitor design |
Biological source | PSEUDOMONAS AERUGINOSA PA01 |
Total number of polymer chains | 2 |
Total formula weight | 51410.60 |
Authors | Moynie, L.,McMahon, S.A.,Alphey, M.S.,Liu, H.,Duthie, F.,Naismith, J.H. (deposition date: 2012-05-30, release date: 2012-12-12, Last modification date: 2023-12-20) |
Primary citation | Moynie, L.,Schnell, R.,Mcmahon, S.A.,Sandalova, T.,Boulkerou, W.A.,Schmidberger, J.W.,Alphey, M.S.,Cukier, C.,Duthie, F.,Kopec, J.,Liu, H.,Jacewicz, A.,Hunter, W.N.,Naismith, J.H.,Schneider, G. The Aeropath Project Targeting Pseudomonas Aeruginosa: Crystallographic Studies for Assessment of Potential Targets in Early-Stage Drug Discovery Acta Crystallogr.,Sect.F, 69:25-, 2013 Cited by PubMed: 23295481DOI: 10.1107/S1744309112044739 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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