3CYV
 
 | |
5YJG
 | | Structural insights into periostin functions | | Descriptor: | CALCIUM ION, CHLORIDE ION, CYSTEINE, ... | | Authors: | Liu, H, Liu, J, Xu, F. | | Deposit date: | 2017-10-10 | | Release date: | 2018-05-23 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.399 Å) | | Cite: | Structural characterizations of human periostin dimerization and cysteinylation.
FEBS Lett., 592, 2018
|
|
8RQF
 | | Cryo-EM structure of human NTCP-Bulevirtide complex | | Descriptor: | Fab-specific nanobody, Heavy chain of Fab3, Light chain of Fab3, ... | | Authors: | Liu, H, Zakrzewicz, D, Nosol, K, Irobalieva, R.N, Mukherjee, S, Bang-Soerensen, R, Goldmann, N, Kunz, S, Rossi, L, Kossiakoff, A.A, Urban, S, Glebe, D, Geyer, J, Locher, K.P. | | Deposit date: | 2024-01-18 | | Release date: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.41 Å) | | Cite: | Cryo-EM structure of human NTCP-Bulevirtide complex
To Be Published
|
|
4HGD
 | | Structural insights into yeast Nit2: C169S mutant of yeast Nit2 in complex with an endogenous peptide-like ligand | | Descriptor: | CACODYLATE ION, GLYCEROL, N-(4-carboxy-4-oxobutanoyl)-L-cysteinylglycine, ... | | Authors: | Liu, H, Qiu, X, Zhang, M, Gao, Y, Niu, L, Teng, M. | | Deposit date: | 2012-10-08 | | Release date: | 2013-07-31 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.04 Å) | | Cite: | Structures of enzyme-intermediate complexes of yeast Nit2: insights into its catalytic mechanism and different substrate specificity compared with mammalian Nit2
Acta Crystallogr.,Sect.D, 69, 2013
|
|
4HG3
 | | Structural insights into yeast Nit2: wild-type yeast Nit2 in complex with alpha-ketoglutarate | | Descriptor: | 2-OXOGLUTARIC ACID, CACODYLATE ION, GLYCEROL, ... | | Authors: | Liu, H, Qiu, X, Zhang, M, Gao, Y, Niu, L, Teng, M. | | Deposit date: | 2012-10-06 | | Release date: | 2013-07-31 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | Structures of enzyme-intermediate complexes of yeast Nit2: insights into its catalytic mechanism and different substrate specificity compared with mammalian Nit2
Acta Crystallogr.,Sect.D, 69, 2013
|
|
4H5U
 | | Structural insights into yeast Nit2: wild-type yeast Nit2 | | Descriptor: | CACODYLATE ION, GLYCEROL, Probable hydrolase NIT2 | | Authors: | Liu, H, Qiu, X, Zhang, M, Gao, Y, Niu, L, Teng, M. | | Deposit date: | 2012-09-18 | | Release date: | 2013-07-31 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.92 Å) | | Cite: | Structures of enzyme-intermediate complexes of yeast Nit2: insights into its catalytic mechanism and different substrate specificity compared with mammalian Nit2
Acta Crystallogr.,Sect.D, 69, 2013
|
|
4HG5
 | | Structural insights into yeast Nit2: wild-type yeast Nit2 in complex with oxaloacetate | | Descriptor: | CACODYLATE ION, GLYCEROL, OXALOACETATE ION, ... | | Authors: | Liu, H, Qiu, X, Zhang, M, Gao, Y, Niu, L, Teng, M. | | Deposit date: | 2012-10-07 | | Release date: | 2013-07-31 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.91 Å) | | Cite: | Structures of enzyme-intermediate complexes of yeast Nit2: insights into its catalytic mechanism and different substrate specificity compared with mammalian Nit2
Acta Crystallogr.,Sect.D, 69, 2013
|
|
6C1Q
 | | Crystal structure of human C5a receptor in complex with an orthosteric antagonist PMX53 and an allosteric antagonist NDT9513727 | | Descriptor: | 1-(1,3-benzodioxol-5-yl)-~{N}-(1,3-benzodioxol-5-ylmethyl)-~{N}-[(3-butyl-2,5-diphenyl-imidazol-4-yl)methyl]methanamine, PMX53, Soluble cytochrome b562, ... | | Authors: | Liu, H, Wang, L, Wei, Z, Zhang, C. | | Deposit date: | 2018-01-05 | | Release date: | 2018-05-30 | | Last modified: | 2020-01-08 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Orthosteric and allosteric action of the C5a receptor antagonists.
Nat. Struct. Mol. Biol., 25, 2018
|
|
4EXN
 | | Crystal structure of mouse Interleukin-34 | | Descriptor: | Interleukin-34, alpha-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Liu, H, Leo, C, Chen, X, Wong, B.R, Williams, L.T, Lin, H, He, X. | | Deposit date: | 2012-04-30 | | Release date: | 2012-05-30 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | The mechanism of shared but distinct CSF-1R signaling by the non-homologous cytokines IL-34 and CSF-1.
Biochim.Biophys.Acta, 1824, 2012
|
|
8CWV
 | |
8JOU
 | | Fiber I and fiber-tail-adaptor of phage GP4 | | Descriptor: | Virion-associated phage protein, rope protein of phage GP4 | | Authors: | Liu, H, Chen, W. | | Deposit date: | 2023-06-08 | | Release date: | 2024-01-03 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Asymmetric Structure of Podophage GP4 Reveals a Novel Architecture of Three Types of Tail Fibers.
J.Mol.Biol., 435, 2023
|
|
8DGV
 | |
3G5C
 | | Structural and biochemical studies on the ectodomain of human ADAM22 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ADAM 22, CALCIUM ION | | Authors: | Liu, H, Shim, A, Chen, X, He, X. | | Deposit date: | 2009-02-04 | | Release date: | 2009-08-18 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.36 Å) | | Cite: | Structural and biochemical studies on the ectodomain of human ADAM22
J.Biol.Chem., 2009
|
|
5XGP
 | | structure of Sizzled from Xenopus laevis at 2.08 angstroms resolution | | Descriptor: | CHLORIDE ION, SULFATE ION, Secreted Xwnt8 inhibitor sizzled | | Authors: | Liu, H, Li, Z, Xu, F. | | Deposit date: | 2017-04-15 | | Release date: | 2017-08-23 | | Last modified: | 2019-12-04 | | Method: | X-RAY DIFFRACTION (2.077 Å) | | Cite: | The crystal structure of full-length Sizzled from Xenopus laevis yields insights into Wnt-antagonistic function of secreted Frizzled-related proteins
J. Biol. Chem., 292, 2017
|
|
3NVX
 | | Molecular mechanism of guidance cue recognition | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Protein A39 | | Authors: | Liu, H, Juo, Z, Shim, A, Focia, P, Chen, X, Garcia, C, He, X. | | Deposit date: | 2010-07-08 | | Release date: | 2010-09-15 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural Basis of Semaphorin-Plexin Recognition and Viral Mimicry from Sema7A and A39R Complexes with PlexinC1.
Cell(Cambridge,Mass.), 142, 2010
|
|
3JA4
 | |
7NA8
 | | Structures of human ghrelin receptor-Gi complexes with ghrelin and a synthetic agonist | | Descriptor: | 1-(methanesulfonyl)-1'-(2-methyl-L-alanyl-O-benzyl-D-seryl)-1,2-dihydrospiro[indole-3,4'-piperidine], Antibody fragment, CHOLESTEROL, ... | | Authors: | Liu, H, Sun, D, Sun, J, Zhang, C. | | Deposit date: | 2021-06-20 | | Release date: | 2021-12-15 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Structural basis of human ghrelin receptor signaling by ghrelin and the synthetic agonist ibutamoren
Nat Commun, 12, 2021
|
|
3JA5
 | |
5XMA
 | |
2JBM
 | | QPRTASE STRUCTURE FROM HUMAN | | Descriptor: | NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE, S,R MESO-TARTARIC ACID | | Authors: | Liu, H, Naismith, J.H. | | Deposit date: | 2006-12-08 | | Release date: | 2007-11-13 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural and Kinetic Characterization of Quinolinate Phosphoribosyltransferase (Hqprtase) from Homo Sapiens.
J.Mol.Biol., 373, 2007
|
|
6A85
 | | Crystal structure of a novel DNA quadruplex | | Descriptor: | AMMONIUM ION, DNA (5'-D(*AP*GP*AP*GP*AP*GP*AP*TP*GP*GP*GP*TP*GP*CP*GP*TP*T)-3'), LEAD (II) ION, ... | | Authors: | Liu, H.H, Gan, J.H. | | Deposit date: | 2018-07-06 | | Release date: | 2019-03-06 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | High-resolution DNA quadruplex structure containing all the A-, G-, C-, T-tetrads.
Nucleic Acids Res., 46, 2018
|
|
5XJZ
 | | Structure of DNA1-Ag complex | | Descriptor: | DNA (5'-D(*GP*CP*AP*CP*GP*CP*GP*C)-3'), SILVER ION, SPERMINE | | Authors: | Liu, H.H, Gan, J.H. | | Deposit date: | 2017-05-04 | | Release date: | 2017-12-06 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (0.98 Å) | | Cite: | A DNA Structure Containing AgI -Mediated G:G and C:C Base Pairs
Angew. Chem. Int. Ed. Engl., 56, 2017
|
|
8CWU
 | |
4LFI
 | | Crystal structure of scCK2 alpha in complex with GMPPNP | | Descriptor: | Casein kinase II subunit alpha, GLYCEROL, MANGANESE (II) ION, ... | | Authors: | Liu, H. | | Deposit date: | 2013-06-27 | | Release date: | 2014-03-05 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | The multiple nucleotide-divalent cation binding modes of Saccharomyces cerevisiae CK2 alpha indicate a possible co-substrate hydrolysis product (ADP/GDP) release pathway.
Acta Crystallogr.,Sect.D, 70, 2014
|
|
8PM6
 | | Human bile salt export pump (BSEP) in complex with inhibitor GBM in nanodiscs | | Descriptor: | 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, Bile salt export pump, CHOLESTEROL | | Authors: | Liu, H, Irobalieva, R.N, Kowal, J, Ni, D, Nosol, K, Bang-Sorensen, R, Lancien, L, Stahlberg, H, Stieger, B, Locher, K.P. | | Deposit date: | 2023-06-28 | | Release date: | 2023-11-22 | | Method: | ELECTRON MICROSCOPY (3.22 Å) | | Cite: | Structural basis of bile salt extrusion and small-molecule inhibition in human BSEP.
Nat Commun, 14, 2023
|
|
