8JJR
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![BU of 8jjr by Molmil](/molmil-images/mine/8jjr) | Cryo-EM structure of Symbiodinium photosystem I | Descriptor: | (3S,3'R,5R,6S,7cis)-7',8'-didehydro-5,6-dihydro-5,6-epoxy-beta,beta-carotene-3,3'-diol, 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ... | Authors: | Zhao, L.S, Wang, N, Li, K, Zhang, Y.Z, Liu, L.N. | Deposit date: | 2023-05-31 | Release date: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Architecture of symbiotic dinoflagellate photosystem I-light-harvesting supercomplex in Symbiodinium. Nat Commun, 15, 2024
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8GSP
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![BU of 8gsp by Molmil](/molmil-images/mine/8gsp) | Complex of FMDV A/WH/CHA/09 and bovine neutralizing scFv antibody W2 | Descriptor: | A/WH/CHA/09 VP1, A/WH/CHA/09 VP2, A/WH/CHA/09 VP3, ... | Authors: | He, Y, Li, K. | Deposit date: | 2022-09-06 | Release date: | 2023-10-11 | Last modified: | 2023-12-06 | Method: | ELECTRON MICROSCOPY (3.75 Å) | Cite: | Conserved antigen structures and antibody-driven variations on foot-and-mouth disease virus serotype A revealed by bovine neutralizing monoclonal antibodies. Plos Pathog., 19, 2023
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8IVZ
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![BU of 8ivz by Molmil](/molmil-images/mine/8ivz) | Crystal structure of talin R7 in complex with KANK1 KN motif | Descriptor: | KN motif and ankyrin repeat domains 1, Talin-1 | Authors: | Xu, Y, Li, K, Wei, Z, Cong, Y. | Deposit date: | 2023-03-29 | Release date: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | KANK1 shapes focal adhesions by orchestrating protein binding, mechanical force sensing, and phase separation. Cell Rep, 42, 2023
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7EO0
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![BU of 7eo0 by Molmil](/molmil-images/mine/7eo0) | FOOT AND MOUTH DISEASE VIRUS O/TIBET/99-BOUND THE SINGLE CHAIN FRAGMEN ANTIBODY C4 | Descriptor: | Ig heavy chain variable region, Ig lamda chain variable region, O/TIBET/99 VP1, ... | Authors: | He, Y, Li, K. | Deposit date: | 2021-04-21 | Release date: | 2021-08-18 | Last modified: | 2022-02-23 | Method: | ELECTRON MICROSCOPY (3.75 Å) | Cite: | Two Cross-Protective Antigen Sites on Foot-and-Mouth Disease Virus Serotype O Structurally Revealed by Broadly Neutralizing Antibodies from Cattle. J.Virol., 95, 2021
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8CXF
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![BU of 8cxf by Molmil](/molmil-images/mine/8cxf) | |
8DHC
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![BU of 8dhc by Molmil](/molmil-images/mine/8dhc) | |
6QD5
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![BU of 6qd5 by Molmil](/molmil-images/mine/6qd5) | X-ray Structure of the Human Urea Channel SLC14A1/UT1 | Descriptor: | CHOLESTEROL HEMISUCCINATE, TETRAETHYLENE GLYCOL, Urea transporter 1, ... | Authors: | Dietz, L, Chi, G, Pike, A.C.W, Moreau, C, Man, H, Snee, M, Scacioc, A, Shrestha, L, Mukhopadhyay, S.M.M, Mckinley, G, Ellis, K, Kliszcak, M, Chalk, R, Borkowska, O, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Durr, K.L, Structural Genomics Consortium (SGC) | Deposit date: | 2018-12-31 | Release date: | 2019-01-09 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.398 Å) | Cite: | X-ray Structure of the Human Urea Channel SLC14A1/UT1 To Be Published
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7Y8A
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![BU of 7y8a by Molmil](/molmil-images/mine/7y8a) | Cryo-EM structure of cryptophyte photosystem I | Descriptor: | (1~{R})-3,5,5-trimethyl-4-[(3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E})-3,7,12,16-tetramethyl-18-[(4~{R})-2,6,6-trimethyl-4-oxidanyl-cyclohexen-1-yl]octadeca-3,5,7,9,11,13,15-heptaen-1,17-diynyl]cyclohex-3-en-1-ol, (1~{R})-3,5,5-trimethyl-4-[(3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-(2,6,6-trimethylcyclohexen-1-yl)octadeca-3,5,7,9,11,13,15,17-octaen-1-ynyl]cyclohex-3-en-1-ol, (1~{R})-3,5,5-trimethyl-4-[(3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-[(1~{R},4~{R})-2,6,6-trimethyl-4-oxidanyl-cyclohex-2-en-1-yl]octadeca-3,5,7,9,11,13,15,17-octaen-1-ynyl]cyclohex-3-en-1-ol, ... | Authors: | Zhao, L.S, Zhang, Y.Z, Liu, L.N, Li, K. | Deposit date: | 2022-06-23 | Release date: | 2023-04-12 | Last modified: | 2023-07-12 | Method: | ELECTRON MICROSCOPY (2.71 Å) | Cite: | Structural basis and evolution of the photosystem I-light-harvesting supercomplex of cryptophyte algae. Plant Cell, 35, 2023
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7Y7B
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![BU of 7y7b by Molmil](/molmil-images/mine/7y7b) | Cryo-EM structure of cryptophyte photosystem I | Descriptor: | (1~{R})-3,5,5-trimethyl-4-[(3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E})-3,7,12,16-tetramethyl-18-[(4~{R})-2,6,6-trimethyl-4-oxidanyl-cyclohexen-1-yl]octadeca-3,5,7,9,11,13,15-heptaen-1,17-diynyl]cyclohex-3-en-1-ol, (1~{R})-3,5,5-trimethyl-4-[(3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-(2,6,6-trimethylcyclohexen-1-yl)octadeca-3,5,7,9,11,13,15,17-octaen-1-ynyl]cyclohex-3-en-1-ol, (1~{R})-3,5,5-trimethyl-4-[(3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-[(1~{R},4~{R})-2,6,6-trimethyl-4-oxidanyl-cyclohex-2-en-1-yl]octadeca-3,5,7,9,11,13,15,17-octaen-1-ynyl]cyclohex-3-en-1-ol, ... | Authors: | Zhao, L.S, Li, K, Zhang, Y.Z, Liu, L.N. | Deposit date: | 2022-06-22 | Release date: | 2023-04-12 | Last modified: | 2023-07-12 | Method: | ELECTRON MICROSCOPY (2.66 Å) | Cite: | Structural basis and evolution of the photosystem I-light-harvesting supercomplex of cryptophyte algae. Plant Cell, 35, 2023
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8F7O
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![BU of 8f7o by Molmil](/molmil-images/mine/8f7o) | BRAF kinase in complex with TAK580 (tovorafenib) | Descriptor: | 6-amino-5-chloro-N-[(1R)-1-(5-{[5-chloro-4-(trifluoromethyl)pyridin-2-yl]carbamoyl}-1,3-thiazol-2-yl)ethyl]pyrimidine-4-carboxamide, Serine/threonine-protein kinase B-raf | Authors: | Tkacik, E, Li, K, Gonzalez Del-Pino, G, Eck, M.J. | Deposit date: | 2022-11-20 | Release date: | 2023-04-12 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (3.54 Å) | Cite: | Structure and RAF family kinase isoform selectivity of type II RAF inhibitors tovorafenib and naporafenib. J.Biol.Chem., 299, 2023
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8F7P
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![BU of 8f7p by Molmil](/molmil-images/mine/8f7p) | BRAF kinase in complex with LXH254 (naporafenib) | Descriptor: | N-{3-[2-(2-hydroxyethoxy)-6-(morpholin-4-yl)pyridin-4-yl]-4-methylphenyl}-2-(trifluoromethyl)pyridine-4-carboxamide, Serine/threonine-protein kinase B-raf | Authors: | Tkacik, E, Li, K, Gonzalez Del-Pino, G, Eck, M.J. | Deposit date: | 2022-11-20 | Release date: | 2023-04-12 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.74 Å) | Cite: | Structure and RAF family kinase isoform selectivity of type II RAF inhibitors tovorafenib and naporafenib. J.Biol.Chem., 299, 2023
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7FEJ
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![BU of 7fej by Molmil](/molmil-images/mine/7fej) | Complex of FMDV A/AF/72 and bovine neutralizing scFv antibody R55 | Descriptor: | A/AF/72 VP1, A/AF/72 VP2, A/AF/72 VP3, ... | Authors: | He, Y, Li, K, Lou, Z. | Deposit date: | 2021-07-20 | Release date: | 2021-09-29 | Last modified: | 2022-02-16 | Method: | ELECTRON MICROSCOPY (3.91 Å) | Cite: | Structures of Foot-and-Mouth Disease Virus with Bovine Neutralizing Antibodies Reveal the Determinant of Intraserotype Cross-Neutralization. J.Virol., 95, 2021
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7FEI
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![BU of 7fei by Molmil](/molmil-images/mine/7fei) | Complex of FMDV A/WH/CHA/09 and bovine neutralizing scFv antibody R55 | Descriptor: | Capsid protein VP0, IG HEAVY CHAIN VARIABLE REGION, IG LAMDA CHAIN VARIABLE REGION | Authors: | He, Y, Li, K, Lou, Z. | Deposit date: | 2021-07-20 | Release date: | 2021-09-29 | Last modified: | 2022-02-16 | Method: | ELECTRON MICROSCOPY (3.91 Å) | Cite: | Structures of Foot-and-Mouth Disease Virus with Bovine Neutralizing Antibodies Reveal the Determinant of Intraserotype Cross-Neutralization. J.Virol., 95, 2021
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7KLP
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![BU of 7klp by Molmil](/molmil-images/mine/7klp) | Crystal structure of a three-tetrad, parallel, K+ stabilized human telomeric G-quadruplex | Descriptor: | HEXAETHYLENE GLYCOL, POTASSIUM ION, telomeric DNA | Authors: | Yatsunyk, L.A, Li, K.S, Chen, E.V. | Deposit date: | 2020-10-30 | Release date: | 2020-12-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Water spines and networks in G-quadruplex structures. Nucleic Acids Res., 49, 2021
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7WVK
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![BU of 7wvk by Molmil](/molmil-images/mine/7wvk) | Crystal structure of human WDR5 in complex with compound 19 | Descriptor: | 1,2-ETHANEDIOL, 1-[2,5-bis(chloranyl)phenyl]sulfonylbenzimidazole, GLYCEROL, ... | Authors: | Han, Q.L, Zhang, X.L, Wang, L, Ren, P.X, Cao, Y, Li, K, Bai, F. | Deposit date: | 2022-02-10 | Release date: | 2022-10-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Discovery, evaluation and mechanism study of WDR5-targeted small molecular inhibitors for neuroblastoma. Acta Pharmacol.Sin., 44, 2023
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6CA0
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![BU of 6ca0 by Molmil](/molmil-images/mine/6ca0) | Cryo-EM structure of E. coli RNAP sigma70 open complex | Descriptor: | DNA (35-MER), DNA (45-MER), DNA (5'-D(P*GP*CP*CP*GP*CP*GP*TP*CP*AP*GP*A)-3'), ... | Authors: | Narayanan, A, Vago, F, Li, K, Qayyum, M.Z, Yernool, D, Jiang, W, Murakami, K.S. | Deposit date: | 2018-01-29 | Release date: | 2018-02-28 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (5.75 Å) | Cite: | Cryo-EM structure ofEscherichia colisigma70RNA polymerase and promoter DNA complex revealed a role of sigma non-conserved region during the open complex formation. J. Biol. Chem., 293, 2018
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5K3I
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![BU of 5k3i by Molmil](/molmil-images/mine/5k3i) | Crystal structure of Acyl-CoA oxidase-1 in Caenorhabditis elegans complexed with FAD and ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Acyl-coenzyme A oxidase, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Zhang, X, Li, K, Jones, R.A, Bruner, S.D, Butcher, R.A. | Deposit date: | 2016-05-19 | Release date: | 2016-08-24 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.683 Å) | Cite: | Structural characterization of acyl-CoA oxidases reveals a direct link between pheromone biosynthesis and metabolic state in Caenorhabditis elegans. Proc.Natl.Acad.Sci.USA, 113, 2016
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6C9Y
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![BU of 6c9y by Molmil](/molmil-images/mine/6c9y) | Cryo-EM structure of E. coli RNAP sigma70 holoenzyme | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Narayanan, A, Vago, F, Li, K, Qayyum, M.Z, Yenool, D, Jiang, W, Murakami, K.S. | Deposit date: | 2018-01-29 | Release date: | 2018-02-28 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.25 Å) | Cite: | Cryo-EM structure ofEscherichia colisigma70RNA polymerase and promoter DNA complex revealed a role of sigma non-conserved region during the open complex formation. J. Biol. Chem., 293, 2018
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5K3H
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![BU of 5k3h by Molmil](/molmil-images/mine/5k3h) | Crystals structure of Acyl-CoA oxidase-1 in Caenorhabditis elegans, Apo form-II | Descriptor: | Acyl-coenzyme A oxidase | Authors: | Zhang, X, Li, K, Jones, R.A, Bruner, S.D, Butcher, R.A. | Deposit date: | 2016-05-19 | Release date: | 2016-08-24 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | Structural characterization of acyl-CoA oxidases reveals a direct link between pheromone biosynthesis and metabolic state in Caenorhabditis elegans. Proc.Natl.Acad.Sci.USA, 113, 2016
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5K3J
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![BU of 5k3j by Molmil](/molmil-images/mine/5k3j) | Crystals structure of Acyl-CoA oxidase-2 in Caenorhabditis elegans bound with FAD, ascaroside-CoA, and ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Acyl-coenzyme A oxidase, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Zhang, X, Li, K, Jones, R.A, Bruner, S.D, Butcher, R.A. | Deposit date: | 2016-05-19 | Release date: | 2016-08-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.68 Å) | Cite: | Structural characterization of acyl-CoA oxidases reveals a direct link between pheromone biosynthesis and metabolic state in Caenorhabditis elegans. Proc.Natl.Acad.Sci.USA, 113, 2016
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5EG8
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![BU of 5eg8 by Molmil](/molmil-images/mine/5eg8) | The cap binding site of influenza virus protein PB2 as a drug target | Descriptor: | Polymerase basic protein 2, THIOCYANATE ION | Authors: | Liu, Y, Zheng, X, Severin, C, Rocha de Moura, T, Li, K, Luo, M. | Deposit date: | 2015-10-26 | Release date: | 2016-02-10 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | The cap-binding site of influenza virus protein PB2 as a drug target. Acta Crystallogr D Struct Biol, 72, 2016
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6QBI
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![BU of 6qbi by Molmil](/molmil-images/mine/6qbi) | NMR structure of BB_P28, Borrelia burgdorferi outer surface lipoprotein | Descriptor: | Surface protein, mlp lipoprotein family | Authors: | Fridmanis, J, Otikovs, M, Brangulis, K, Jaudzems, K. | Deposit date: | 2018-12-21 | Release date: | 2020-01-29 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of Borrelia burgdorferi outer surface lipoprotein BBP28, a member of the mlp protein family. Proteins, 2020
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6QS0
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![BU of 6qs0 by Molmil](/molmil-images/mine/6qs0) | |
6D2I
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![BU of 6d2i by Molmil](/molmil-images/mine/6d2i) | JAK2 Pseudokinase V617F in complex with AT9283 | Descriptor: | 1-cyclopropyl-3-{3-[5-(morpholin-4-ylmethyl)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl}urea, Tyrosine-protein kinase | Authors: | Li, Q, Li, K, Eck, M.J. | Deposit date: | 2018-04-13 | Release date: | 2019-03-20 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.192 Å) | Cite: | Discovery and Structural Characterization of ATP-Site Ligands for the Wild-Type and V617F Mutant JAK2 Pseudokinase Domain. ACS Chem. Biol., 14, 2019
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7K56
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![BU of 7k56 by Molmil](/molmil-images/mine/7k56) | Structure of VCP dodecamer purified from H1299 cells | Descriptor: | Transitional endoplasmic reticulum ATPase | Authors: | Yu, G, Bai, Y, Li, K, Jiang, W, Zhang, Z.Y. | Deposit date: | 2020-09-16 | Release date: | 2021-10-13 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Cryo-electron microscopy structures of VCP/p97 reveal a new mechanism of oligomerization regulation. Iscience, 24, 2021
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