5UXT
| Coiled-coil Trimer with Glu:Trp:Lys Triad | Descriptor: | GLYCEROL, coiled-coil trimer with Glu:Trp:Lys triad | Authors: | Smith, M.S, Billings, W.M, Whitby, F.G, Miller, M.B, Price, J.L. | Deposit date: | 2017-02-23 | Release date: | 2017-08-09 | Method: | X-RAY DIFFRACTION (2.197 Å) | Cite: | Enhancing a long-range salt bridge with intermediate aromatic and nonpolar amino acids. Org. Biomol. Chem., 15, 2017
|
|
2W9P
| Crystal Structure of Potato Multicystatin | Descriptor: | MULTICYSTATIN | Authors: | Nissen, M.S, Kumar, G.N, Youn, B, Knowles, D.B, Lam, K.S, Ballinger, W.J, Knowles, N.R, Kang, C. | Deposit date: | 2009-01-28 | Release date: | 2010-02-02 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Characterization of Solanum Tuberosum Multicystatin and its Structural Comparison with Other Cystatins. Plant Cell, 21, 2009
|
|
3M10
| Substrate-free form of Arginine Kinase | Descriptor: | Arginine kinase, SULFATE ION | Authors: | Yousef, M.S, Clark, S.A, Pruett, P.K, Somasundaram, T, Ellington, W.R, Chapman, M.S. | Deposit date: | 2010-03-03 | Release date: | 2010-03-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.727 Å) | Cite: | Arginine kinase: joint crystallographic and NMR RDC analyses link substrate-associated motions to intrinsic flexibility. J.Mol.Biol., 405, 2011
|
|
1Z6J
| Crystal Structure of a ternary complex of Factor VIIa/Tissue Factor/Pyrazinone Inhibitor | Descriptor: | 5-[AMINO(IMINO)METHYL]-2-[({[6-[3-AMINO-5-({[(1R)-1-METHYLPROPYL]AMINO}CARBONYL)PHENYL]-3-(ISOPROPYLAMINO)-2-OXOPYRAZIN-1(2H)-YL]ACETYL}AMINO)METHYL]-N-PYRIDIN-4-YLBENZAMIDE, CALCIUM ION, Coagulation factor VII, ... | Authors: | Schweitzer, B.A, Neumann, W.L, Rahman, H.K, Kusturin, C.L, Sample, K.R, Poda, G.I, Kurumbail, R.G, Stevens, A.M, Stegeman, R.A, Stallings, W.C. | Deposit date: | 2005-03-22 | Release date: | 2005-05-03 | Last modified: | 2019-07-24 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure-based design and synthesis of pyrazinones containing novel P1 'side pocket' moieties as inhibitors of TF/VIIa. Bioorg.Med.Chem.Lett., 15, 2005
|
|
1PXX
| CRYSTAL STRUCTURE OF DICLOFENAC BOUND TO THE CYCLOOXYGENASE ACTIVE SITE OF COX-2 | Descriptor: | 2-[2,6-DICHLOROPHENYL)AMINO]BENZENEACETIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Kiefer, J.R, Rowlinson, S.W, Prusakiewicz, J.J, Pawlitz, J.L, Kozak, K.R, Kalgutkar, A.S, Stallings, W.C, Marnett, L.J, Kurumbail, R.G. | Deposit date: | 2003-07-07 | Release date: | 2003-09-09 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | A Novel Mechanism of Cyclooxygenase-2 Inhibition Involving Interactions with Ser-530 and Tyr-385. J.Biol.Chem., 278, 2003
|
|
1UB1
| Solution structure of the matrix attachment region-binding domain of chicken MeCP2 | Descriptor: | attachment region binding protein | Authors: | Heitmann, B, Maurer, T, Weitzel, J.M, Stratling, W.H, Kalbitzer, H.R, Brunner, E, Structural Proteomics in Europe (SPINE) | Deposit date: | 2003-03-27 | Release date: | 2003-08-05 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution structure of the matrix attachment region-binding domain of chicken MeCP2 EUR.J.BIOCHEM., 270, 2003
|
|
6Q22
| Coiled-coil Trimer with Glu:Aminobutyric acid:Lys Triad | Descriptor: | Coiled-coil Trimer with Glu:Aminobutyric acid:Lys Triad, PENTAETHYLENE GLYCOL | Authors: | Smith, M.S, Stern, K.L, Billings, W.M, Price, J.L. | Deposit date: | 2019-08-06 | Release date: | 2020-04-29 | Last modified: | 2020-05-20 | Method: | X-RAY DIFFRACTION (1.599 Å) | Cite: | Context-Dependent Stabilizing Interactions among Solvent-Exposed Residues along the Surface of a Trimeric Helix Bundle. Biochemistry, 59, 2020
|
|
6Q25
| |
4COX
| |
1R35
| MURINE INDUCIBLE NITRIC OXIDE SYNTHASE OXYGENASE DIMER, TETRAHYDROBIOPTERIN AND 4R-FLUORO-N6-ETHANIMIDOYL-L-LYSINE | Descriptor: | 4R-FLUORO-N6-ETHANIMIDOYL-L-LYSINE, 5,6,7,8-TETRAHYDROBIOPTERIN, Nitric oxide synthase, ... | Authors: | Shieh, H.S, Stevens, A.M, Stallings, W.C. | Deposit date: | 2003-09-30 | Release date: | 2004-10-05 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | 4-Fluorinated L-lysine analogs as selective i-NOS inhibitors: methodology for introducing fluorine into the lysine side chain. Org.Biomol.Chem., 1, 2003
|
|
6U47
| |
6V4Y
| |
6V50
| |
6V58
| |
6V5G
| Coiled-coil Trimer with Ala:Leu:Lys Triad | Descriptor: | Coiled-coil Trimer with Ala:Leu:Lys Triad, PENTAETHYLENE GLYCOL | Authors: | Smith, M.S, Stern, K.L, Billings, W.M, Price, J.L. | Deposit date: | 2019-12-04 | Release date: | 2020-04-29 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Context-Dependent Stabilizing Interactions among Solvent-Exposed Residues along the Surface of a Trimeric Helix Bundle. Biochemistry, 59, 2020
|
|
6V57
| |
6V5I
| Coiled-coil Trimer with Ala:Leu:Ala Triad | Descriptor: | Coiled-coil Trimer with Ala:Leu:Ala Triad, PENTAETHYLENE GLYCOL | Authors: | Smith, M.S, Stern, K.L, Billings, W.M, Price, J.L. | Deposit date: | 2019-12-04 | Release date: | 2020-04-29 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Context-Dependent Stabilizing Interactions among Solvent-Exposed Residues along the Surface of a Trimeric Helix Bundle. Biochemistry, 59, 2020
|
|
6V5J
| |
1SD0
| Structure of arginine kinase C271A mutant | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ARGININE, Arginine kinase, ... | Authors: | Gattis, J.L, Ruben, E, Fenley, M.O, Ellington, W.R, Chapman, M.S. | Deposit date: | 2004-02-12 | Release date: | 2004-07-27 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The active site cysteine of arginine kinase: structural and functional analysis of partially active mutants Biochemistry, 43, 2004
|
|
1P50
| Transition state structure of an Arginine Kinase mutant | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ARGININE, Arginine kinase, ... | Authors: | Pruett, P.S, Azzi, A, Clark, S.A, Yousef, M.S, Gattis, J.L, Somasundarum, T, Ellington, W.R, Chapman, M.S. | Deposit date: | 2003-04-24 | Release date: | 2003-06-17 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The putative catalytic bases have, at most, an accessory role in the mechanism of arginine kinase. J.Biol.Chem., 278, 2003
|
|
1P52
| Structure of Arginine kinase E314D mutant | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Arginine kinase, D-ARGININE, ... | Authors: | Pruett, P.S, Azzi, A, Clark, S.A, Yousef, M.S, Gattis, J.L, Somasundarum, T, Ellington, W.R, Chapman, M.S. | Deposit date: | 2003-04-24 | Release date: | 2003-06-17 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The putative catalytic bases have, at most, an accessory role in the mechanism of arginine kinase. J.Biol.Chem., 278, 2003
|
|
1MNG
| STRUCTURE-FUNCTION IN E. COLI IRON SUPEROXIDE DISMUTASE: COMPARISONS WITH THE MANGANESE ENZYME FROM T. THERMOPHILUS | Descriptor: | AZIDE ION, MANGANESE (II) ION, MANGANESE SUPEROXIDE DISMUTASE | Authors: | Lah, M.S, Dixon, M, Pattridge, K.A, Stallings, W.C, Fee, J.A, Ludwig, M.L. | Deposit date: | 1994-07-13 | Release date: | 1994-10-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure-function in Escherichia coli iron superoxide dismutase: comparisons with the manganese enzyme from Thermus thermophilus. Biochemistry, 34, 1995
|
|
1R0Q
| Characterization of the conversion of the malformed, recombinant cytochrome rc552 to a 2-formyl-4-vinyl (Spirographis) heme | Descriptor: | 2-FORMYL-PROTOPORPHRYN IX, Cytochrome c-552 | Authors: | Fee, J.A, Todaro, T.R, Luna, E, Sanders, D, Hunsicker-Wang, L.M, Patel, K.M, Bren, K.L, Gomez-Moran, E, Hill, M.G, Ai, J, Loehr, T.M, Oertling, W.A, Williams, P.A, Stout, C.D, McRee, D, Pastuszyn, A. | Deposit date: | 2003-09-22 | Release date: | 2004-09-28 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | Cytochrome rC552, formed during expression of the truncated, Thermus thermophilus cytochrome c552 gene in the cytoplasm of Escherichia coli, reacts spontaneously to form protein-bound 2-formyl-4-vinyl (Spirographis) heme. Biochemistry, 43, 2004
|
|
1QYZ
| Characterization of the malformed, recombinant cytochrome rC552 | Descriptor: | 2-ACETYL-PROTOPORPHYRIN IX, Cytochrome c-552 | Authors: | Fee, J.A, Todaro, T.R, Luna, E, Sanders, D, Hunsicker-Wang, L.M, Patel, K.M, Bren, K.L, Gomez-Moran, E, Hill, M.G, Ai, J, Loehr, T.M, Oertling, W.A, Williams, P.A, Stout, C.D, McRee, D, Pastuszyn, A. | Deposit date: | 2003-09-12 | Release date: | 2004-09-28 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Cytochrome rC552, formed during expression of the truncated, Thermus thermophilus cytochrome c552 gene in the cytoplasm of Escherichia coli, reacts spontaneously to form protein-bound 2-formyl-4-vinyl (Spirographis) heme. Biochemistry, 43, 2004
|
|
1DDX
| CRYSTAL STRUCTURE OF A MIXTURE OF ARACHIDONIC ACID AND PROSTAGLANDIN BOUND TO THE CYCLOOXYGENASE ACTIVE SITE OF COX-2: PROSTAGLANDIN STRUCTURE | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 7-[6-(3-HYDROPEROXY-OCT-1-ENYL)-2,3-DIOXA-BICYCLO[2.2.1]HEPT-5-YL]-HEPT-5-ENOIC ACID, ... | Authors: | Kiefer, J.R, Pawlitz, J.L, Moreland, K.T, Stegeman, R.A, Gierse, J.K, Stevens, A.M, Goodwin, D.C, Rowlinson, S.W, Marnett, L.J, Stallings, W.C, Kurumbail, R.G. | Deposit date: | 1999-11-11 | Release date: | 2000-05-16 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural insights into the stereochemistry of the cyclooxygenase reaction. Nature, 405, 2000
|
|