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PDB: 458 件

3M3A
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The roles of glutamates and metal ions in a rationally designed nitric oxide reductase based on myoglobin: Cu(II)-I107E FeBMb (Cu(II) binding to FeB site)
分子名称: COPPER (II) ION, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE
著者Lin, Y.-W, Yeung, N, Gao, Y.-G, Miner, K.D, Tian, S, Robinson, H, Lu, Y.
登録日2010-03-08
公開日2010-05-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献Roles of glutamates and metal ions in a rationally designed nitric oxide reductase based on myoglobin.
Proc.Natl.Acad.Sci.USA, 107, 2010
5K29
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Trypanosoma brucei bromodomain BDF5 (Tb427tmp.01.5000)
分子名称: UNKNOWN ATOM OR ION, uncharacterized protein BDF5
著者Lin, Y.H, Tempel, W, Walker, J.R, Loppnau, P, Amani, M, Hou, C.F.D, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Hui, R, Structural Genomics Consortium (SGC)
登録日2016-05-18
公開日2016-07-13
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Trypanosoma brucei bromodomain BDF5 (Tb427tmp.01.5000)
To Be Published
5GCN
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BU of 5gcn by Molmil
CATALYTIC DOMAIN OF TETRAHYMENA GCN5 HISTONE ACETYLTRANSFERASE IN COMPLEX WITH COENZYME A
分子名称: COENZYME A, HISTONE ACETYLTRANSFERASE GCN5
著者Lin, Y, Fletcher, C.M, Zhou, J, Allis, C.D, Wagner, G.
登録日1999-03-24
公開日1999-07-19
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the catalytic domain of GCN5 histone acetyltransferase bound to coenzyme A
Nature, 400, 1999
8GRZ
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BU of 8grz by Molmil
X-ray crystal structure of V71C human neuroglobin mutant
分子名称: Neuroglobin, PROTOPORPHYRIN IX CONTAINING FE
著者Lin, Y.W.
登録日2022-09-03
公開日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献X-ray crystal structure of V71C human neuroglobin mutant
To Be Published
5TPX
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BU of 5tpx by Molmil
Bromodomain from Plasmodium Faciparum Gcn5, complexed with compound
分子名称: (1S,2S)-N~1~,N~1~-dimethyl-N~2~-(3-methyl[1,2,4]triazolo[3,4-a]phthalazin-6-yl)-1-phenylpropane-1,2-diamine, CHLORIDE ION, Histone acetyltransferase GCN5, ...
著者Lin, Y.H, Hou, C.F.D, MOUSTAKIM, M, DIXON, D.J, Loppnau, P, Tempel, W, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Hui, R, BRENNAN, P.E, Walker, J.R, Structural Genomics Consortium (SGC)
登録日2016-10-21
公開日2017-01-04
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Discovery of a PCAF Bromodomain Chemical Probe.
Angew. Chem. Int. Ed. Engl., 56, 2017
5TCM
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First Bromodomain from Leishmania donovani LdBPK.091320 complexed with BI-2536
分子名称: 1,2-ETHANEDIOL, 4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide, Uncharacterized protein
著者Lin, Y.H, Hou, C.F.D, Loppnau, P, Dong, A, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Hui, R, Walker, J.R, Structural Genomics Consortium (SGC)
登録日2016-09-15
公開日2016-10-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献First Bromodomain from Leishmania donovani LdBPK.091320 complexed with BI-2536
To be published
6JP1
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An X-ray structure of met sperm whale F43Y/T67R myoglobin with Tyr-heme double cross-links
分子名称: Myoglobin, PROTOPORPHYRIN IX CONTAINING FE
著者Lin, Y.W, Yuan, H.
登録日2019-03-25
公開日2019-05-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Unique Tyr-heme double cross-links in F43Y/T67R myoglobin: an artificial enzyme with a peroxidase activity comparable to that of native peroxidases.
Chem.Commun.(Camb.), 55, 2019
1YWY
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BU of 1ywy by Molmil
Solution Structure of Pseudomonas aeruginosa Protein PA2021. The Northeast Structural Genomics Consortium Target Pat85.
分子名称: hypothetical protein PA2021
著者Lin, Y.C, Liu, G, Shen, Y, Yee, A, Arrowsmith, C.H, Szyperski, T, Northeast Structural Genomics Consortium (NESG)
登録日2005-02-18
公開日2005-04-12
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution Structure of Pseudomonas aeruginosa Protein PA2021.
To be Published
5I10
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BU of 5i10 by Molmil
Crystal structure of spinosyn rhamnosyl 4'-O-methyltransferase spnh mutant T242Q from Saccharopolyspora Spinosa
分子名称: MAGNESIUM ION, Probable O-methyltransferase
著者Lin, Y.-C, Huang, S.-P, Huang, B.-L, Chen, Y.-H, Chen, Y.-J, Chiu, H.-T.
登録日2016-02-05
公開日2017-02-08
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of spinosyn rhamnosyl 4'-O-methyltransferase spnh mutant T242Q from Saccharopolyspora Spinosa
To Be Published
8J0A
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Robust design of effective allosteric activator UbV R4 for Rsp5 E3 ligase using the machine-learning tool ProteinMPNN
分子名称: SULFATE ION, Ubiquitin variant R4
著者Lin, Y.-F, Hsieh, Y.-J, Kao, H.-W, Ko, T.-P, Wu, K.-P.
登録日2023-04-10
公開日2023-08-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Robust Design of Effective Allosteric Activators for Rsp5 E3 Ligase Using the Machine Learning Tool ProteinMPNN.
Acs Synth Biol, 12, 2023
3OGQ
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BU of 3ogq by Molmil
Crystal Structure of 6s-98S FIV Protease with Lopinavir bound
分子名称: DIMETHYL SULFOXIDE, FIV protease, N-{1-BENZYL-4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-5-PHENYL-PENTYL}-3-METHYL-2-(2-OXO-TETRAHYDRO-PYRIMIDIN-1-YL)-BUTYRAMIDE
著者Lin, Y.-C, Perryman, A.L, Elder, J.H, Stout, C.D.
登録日2010-08-17
公開日2011-06-08
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for drug and substrate specificity exhibited by FIV encoding a chimeric FIV/HIV protease.
Acta Crystallogr.,Sect.D, 67, 2011
3OGP
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BU of 3ogp by Molmil
Crystal Structure of 6s-98S FIV Protease with Darunavir bound
分子名称: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, DIMETHYL SULFOXIDE, FIV Protease
著者Lin, Y.-C, Perryman, A.L, Elder, J.H, Stout, C.D.
登録日2010-08-17
公開日2011-06-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural basis for drug and substrate specificity exhibited by FIV encoding a chimeric FIV/HIV protease.
Acta Crystallogr.,Sect.D, 67, 2011
6V6U
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BU of 6v6u by Molmil
Crystal structure of RhoA-GDP with novel Switch I conformation
分子名称: 1,4-DIETHYLENE DIOXIDE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Lin, Y, Zheng, Y.
登録日2019-12-06
公開日2020-12-23
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.16 Å)
主引用文献Structure of an inactive conformation of GTP-bound RhoA GTPase.
Structure, 29, 2021
6V6M
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BU of 6v6m by Molmil
Crystal structure of an inactive state of GMPPNP-bound RhoA
分子名称: 1,4-DIETHYLENE DIOXIDE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
著者Lin, Y, Zheng, Y.
登録日2019-12-05
公開日2020-12-09
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献Structure of an inactive conformation of GTP-bound RhoA GTPase.
Structure, 29, 2021
6V6V
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Crystal structure of oncogenic RhoA mutant G14V complexed with GDP
分子名称: 1,4-DIETHYLENE DIOXIDE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Lin, Y, Zheng, Y.
登録日2019-12-06
公開日2020-12-23
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structure of an inactive conformation of GTP-bound RhoA GTPase.
Structure, 29, 2021
4IT8
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BU of 4it8 by Molmil
A sperm whale myoglobin mutant L29H Mb with two distal histidines
分子名称: Myoglobin, PROTOPORPHYRIN IX CONTAINING FE
著者Lin, Y.-W, Tan, X.-S, Li, W, Sun, M.-H, Wen, G.-B, Liu, J.-H.
登録日2013-01-18
公開日2013-04-10
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural and nitrite reductase activity comparisons of myoglobins with one to three distal histidines.
RSC Adv, 2013
3CGP
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BU of 3cgp by Molmil
X-ray structure of a pseudouridine-containing yeast spliceosomal U2 snRNA-intron branch site duplex bound to iodide ions
分子名称: IODIDE ION, RNA (5'-R(*CP*GP*CP*UP*AP*CP*UP*AP*AP*CP*GP*CP*G)-3'), RNA (5'-R(*GP*CP*GP*CP*GP*(PSU)P*AP*GP*UP*AP*GP*C)-3'), ...
著者Lin, Y, Kielkopf, C.L.
登録日2008-03-06
公開日2008-07-01
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献X-ray structures of U2 snRNA-branchpoint duplexes containing conserved pseudouridines.
Biochemistry, 47, 2008
3CGS
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BU of 3cgs by Molmil
X-ray structure containing the pseudouridylated U2 snRNA and mammalian intron branch site consensus sequences
分子名称: MAGNESIUM ION, RNA (5'-R(*CP*GP*CP*UP*AP*CP*UP*GP*AP*CP*GP*CP*G)-3'), RNA (5'-R(*GP*CP*GP*CP*GP*(PSU)P*AP*GP*UP*AP*GP*C)-3')
著者Lin, Y, Kielkopf, C.L.
登録日2008-03-06
公開日2008-07-01
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献X-ray structures of U2 snRNA-branchpoint duplexes containing conserved pseudouridines.
Biochemistry, 47, 2008
3CGR
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BU of 3cgr by Molmil
X-ray structure containing the pseudouridylated U2 snRNA and intron branch site consensus sequences
分子名称: RNA (5'-R(*CP*GP*CP*AP*CP*UP*AP*AP*CP*CP*GP*CP*G)-3'), RNA (5'-R(*GP*CP*GP*CP*GP*GP*(PSU)P*AP*GP*UP*GP*C)-3'), SULFATE ION
著者Lin, Y, Kielkopf, C.L.
登録日2008-03-06
公開日2008-07-01
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献X-ray structures of U2 snRNA-branchpoint duplexes containing conserved pseudouridines.
Biochemistry, 47, 2008
8WUB
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BU of 8wub by Molmil
The X-ray structure of human neuroglobin C120S mutant
分子名称: Neuroglobin, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
著者Lin, Y.W, Yuan, H.
登録日2023-10-20
公開日2024-10-23
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The X-ray structure of human neuroglobin C120S mutant
To Be Published
3CGQ
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X-ray structure of a pseudouridine-containing yeast spliceosomal U2 snRNA-intron branch site duplex
分子名称: RNA (5'-R(*CP*GP*CP*UP*AP*CP*UP*AP*AP*CP*GP*CP*G)-3'), RNA (5'-R(*GP*CP*GP*CP*GP*(PSU)P*AP*GP*UP*AP*GP*C)-3'), SULFATE ION
著者Lin, Y, Kielkopf, C.L.
登録日2008-03-06
公開日2008-07-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献X-ray structures of U2 snRNA-branchpoint duplexes containing conserved pseudouridines.
Biochemistry, 47, 2008
5XGF
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The fatty acid-responsive FadR repressor of Vibrio alginolyticus
分子名称: Fatty acid metabolism regulator protein, NICKEL (II) ION
著者Lin, Y, Li, D.F, Feng, Y.J.
登録日2017-04-13
公開日2017-05-31
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Snapshort of Vibrio FadR-ligand complex structure reveals a new mechanism for bacterial fatty acid sensing
To Be Published
4LPI
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BU of 4lpi by Molmil
A sperm whale myoglobin double mutant L29H/F43Y Mb with a distal hydrogen-bonding network
分子名称: Myoglobin, PROTOPORPHYRIN IX CONTAINING FE
著者Lin, Y.
登録日2013-07-16
公開日2014-07-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.36 Å)
主引用文献How a novel tyrosine-heme cross-link fine-tunes the structure and functions of heme proteins: a direct comparitive study of L29H/F43Y myoglobin
Dalton Trans, 44, 2015
2JNS
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Solution structure of the Bromodomain-containing protein 4 ET domain
分子名称: Bromodomain-containing protein 4
著者Lin, Y.J, Padmanabhan, B, Yokoyama, S, Guntert, P, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-02-01
公開日2008-02-05
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Solution structure of the Bromodomain-containing protein 4 ET domain
To be Published
2FHZ
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Molecular Basis of Inhibition of the Ribonuclease Activity in Colicin E5 by Its Cognate Immunity Protein
分子名称: Colicin-E5, Colicin-E5 immunity protein
著者Lin, Y.L, Huang, R.H.
登録日2005-12-27
公開日2006-03-28
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Molecular basis of inhibition of the ribonuclease activity in colicin e5 by its cognate immunity protein
J.Mol.Biol., 358, 2006

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