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PDB: 80 results
6LOI
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BU of 6loi by Molmil
Crystal structure of Enterococcus faecalis Undecaprenyl pyrophosphate synthase(EfaUPPS)
Descriptor: Isoprenyl transferase
Authors:Lin, W, Wang, C.Y, Li, W.J, Wang, F.L.
Deposit date:2020-01-05
Release date:2020-06-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.503 Å)
Cite:Investigations into the Antibacterial Mechanism of Action of Viridicatumtoxins.
Acs Infect Dis., 6, 2020
6DVD
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BU of 6dvd by Molmil
Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor L) with 6 nt spacer and bromine labelled in position "-11
Descriptor: DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*A)-3'), DNA (5'-D(P*CP*GP*TP*GP*TP*CP*AP*GP*TP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ...
Authors:Lin, W, Das, K, Feng, Y, Ebright, R.H.
Deposit date:2018-06-23
Release date:2019-02-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.899 Å)
Cite:Structural basis of ECF-sigma-factor-dependent transcription initiation.
Nat Commun, 10, 2019
6DVE
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BU of 6dve by Molmil
Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF selenomethionine-labelled sigma factor L) with 6 nt spacer
Descriptor: DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*T)-3'), DNA (5'-D(P*CP*GP*TP*GP*TP*GP*AP*GP*TP*AP*AP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ...
Authors:Lin, W, Das, K, Feng, Y, Ebright, R.H.
Deposit date:2018-06-23
Release date:2019-02-20
Last modified:2019-02-27
Method:X-RAY DIFFRACTION (3.812 Å)
Cite:Structural basis of ECF-sigma-factor-dependent transcription initiation.
Nat Commun, 10, 2019
6DV9
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BU of 6dv9 by Molmil
Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor L) containing 5nt RNA with 4nt spacer
Descriptor: DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*G)-3'), DNA (5'-D(P*CP*GP*TP*GP*TP*CP*AP*GP*AP*GP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ...
Authors:Lin, W, Das, K, Feng, Y, Ebright, R.H.
Deposit date:2018-06-23
Release date:2019-02-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural basis of ECF-sigma-factor-dependent transcription initiation.
Nat Commun, 10, 2019
6DVB
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BU of 6dvb by Molmil
Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor L) containing 5nt RNA with 5nt spacer
Descriptor: DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*G)-3'), DNA (5'-D(P*CP*GP*TP*GP*TP*CP*AP*GP*TP*AP*GP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ...
Authors:Lin, W, Das, K, Feng, Y, Ebright, R.H.
Deposit date:2018-06-23
Release date:2019-02-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural basis of ECF-sigma-factor-dependent transcription initiation.
Nat Commun, 10, 2019
6DVC
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BU of 6dvc by Molmil
Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor L) containing 5nt RNA with 6nt spacer
Descriptor: DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*G)-3'), DNA (5'-D(P*CP*GP*TP*GP*TP*CP*AP*GP*TP*AP*GP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ...
Authors:Lin, W, Das, K, Feng, Y, Ebright, R.H.
Deposit date:2018-06-23
Release date:2019-02-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural basis of ECF-sigma-factor-dependent transcription initiation.
Nat Commun, 10, 2019
7WMW
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BU of 7wmw by Molmil
Crystal structure of methylenetetrahydrofolate reductase MSMEG_6649 from Mycobacterium smegmatis
Descriptor: Methylenetetrahydrofolate reductase
Authors:Lin, W, Wang, W.
Deposit date:2022-01-17
Release date:2023-01-25
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.053 Å)
Cite:Structural and functional characterization of a mycobacterial methylenetetrahydrofolate reductase utilizing NADH as the exclusive cofactor.
Biochem.J., 480, 2023
7WMY
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BU of 7wmy by Molmil
Crystal structure of methylenetetrahydrofolate reductase MSMEG_6649 from Mycobacterium smegmatis with 5-methyltetrahydrofolate
Descriptor: methylenetetrahydrofolate reductase
Authors:Lin, W, Wang, W.
Deposit date:2022-01-17
Release date:2023-01-25
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.266 Å)
Cite:Structural and functional characterization of a mycobacterial methylenetetrahydrofolate reductase utilizing NADH as the exclusive cofactor.
Biochem.J., 480, 2023
7WMX
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BU of 7wmx by Molmil
Crystal structure of methylenetetrahydrofolate reductase MSMEG_6649 from Mycobacterium smegmatis with 5,10-methylenetetrahydrofolate
Descriptor: Methylenetetrahydrofolate reductase
Authors:Lin, W, Wang, W.
Deposit date:2022-01-17
Release date:2023-01-25
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.264 Å)
Cite:Structural and functional characterization of a mycobacterial methylenetetrahydrofolate reductase utilizing NADH as the exclusive cofactor.
Biochem.J., 480, 2023
7WMZ
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BU of 7wmz by Molmil
Crystal structure of methylenetetrahydrofolate reductase MSMEG_6649 from Mycobacterium smegmatis with NADH
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Methylenetetrahydrofolate reductase
Authors:Lin, W, Wang, W.
Deposit date:2022-01-17
Release date:2023-01-25
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.916 Å)
Cite:Structural and functional characterization of a mycobacterial methylenetetrahydrofolate reductase utilizing NADH as the exclusive cofactor.
Biochem.J., 480, 2023
7W5Y
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BU of 7w5y by Molmil
Cryo-EM structure of SoxS-dependent transcription activation complex with fpr promoter DNA
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Lin, W, Feng, Y.
Deposit date:2021-11-30
Release date:2022-10-26
Last modified:2022-11-16
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural basis of three different transcription activation strategies adopted by a single regulator SoxS.
Nucleic Acids Res., 50, 2022
7W5X
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BU of 7w5x by Molmil
Cryo-EM structure of SoxS-dependent transcription activation complex with zwf promoter DNA
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Lin, W, Feng, Y, Shi, J.
Deposit date:2021-11-30
Release date:2022-10-26
Last modified:2022-11-16
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis of three different transcription activation strategies adopted by a single regulator SoxS.
Nucleic Acids Res., 50, 2022
7W5W
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BU of 7w5w by Molmil
Cryo-EM structure of SoxS-dependent transcription activation complex with micF promoter DNA
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Lin, W, Feng, Y.
Deposit date:2021-11-30
Release date:2022-10-26
Last modified:2022-11-16
Method:ELECTRON MICROSCOPY (4.55 Å)
Cite:Structural basis of three different transcription activation strategies adopted by a single regulator SoxS.
Nucleic Acids Res., 50, 2022
7C7E
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BU of 7c7e by Molmil
Crystal structure of C terminal domain of Escherichia coli DgoR
Descriptor: Putative DNA-binding transcriptional regulator, SULFATE ION, TRIETHYLENE GLYCOL, ...
Authors:Lin, W.
Deposit date:2020-05-25
Release date:2021-01-20
Method:X-RAY DIFFRACTION (2.047 Å)
Cite:Structural and Functional Analyses of the Transcription Repressor DgoR From Escherichia coli Reveal a Divalent Metal-Containing D-Galactonate Binding Pocket.
Front Microbiol, 11, 2020
7VWZ
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BU of 7vwz by Molmil
Cryo-EM structure of Rob-dependent transcription activation complex in a unique conformation
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Lin, W, Feng, Y, Shi, J.
Deposit date:2021-11-12
Release date:2022-06-08
Last modified:2022-06-22
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural basis of transcription activation by Rob, a pleiotropic AraC/XylS family regulator.
Nucleic Acids Res., 50, 2022
7VWY
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BU of 7vwy by Molmil
Cryo-EM structure of Rob-dependent transcription activation complex in a unique conformation
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Lin, W, Feng, Y.
Deposit date:2021-11-12
Release date:2022-06-08
Last modified:2023-06-07
Method:ELECTRON MICROSCOPY (4.57 Å)
Cite:Structural basis of transcription activation by Rob, a pleiotropic AraC/XylS family regulator.
Nucleic Acids Res., 50, 2022
7VR2
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BU of 7vr2 by Molmil
Crystal structure of (-)-pulegone reductase PR1292 from Nepeta tenuifolia
Descriptor: (-)-pulegone reductase PR1292 from Nepeta tenuifolia
Authors:Lin, W, Wang, W.W.
Deposit date:2021-10-21
Release date:2022-10-26
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of (-)-pulegone reductase PR1292 from Nepeta tenuifolia
To Be Published
7VR4
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BU of 7vr4 by Molmil
Crystal structure of (-)-pulegone reductase PR1294 from Nepeta tenuifolia in complex with NADPH
Descriptor: (-)-pulegone reductase PR1294 from Nepeta tenuifolia in complex with NADPH, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Lin, W, Wang, W.W.
Deposit date:2021-10-21
Release date:2022-10-26
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Crystal structure of (-)-pulegone reductase PR1294 from Nepeta tenuifolia in complex with NADPH
To Be Published
8HIG
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BU of 8hig by Molmil
Co-crystal structure of C-terminal DNA binding domain of Saccharopolyspora erythraea GlnR in complex with its cognate promoter DNA
Descriptor: DNA (5'-D(*AP*CP*GP*TP*AP*AP*CP*AP*TP*CP*GP*CP*GP*GP*TP*AP*AP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*TP*TP*AP*CP*CP*GP*CP*GP*AP*TP*GP*TP*TP*AP*CP*GP*T)-3'), DNA-binding response OmpR family regulator
Authors:Lin, W, Xu, J.C, Zhang, Y.
Deposit date:2022-11-20
Release date:2023-11-22
Method:X-RAY DIFFRACTION (2.329 Å)
Cite:Co-crystal structure of C-terminal DNA binding domain of Saccharopolyspora erythraea GlnR in complex with its cognate promoter DNA
To Be Published
7DE3
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BU of 7de3 by Molmil
Human adenylate kinase 1 (hAK1) mutant-R128W
Descriptor: Adenylate kinase isoenzyme 1
Authors:Lin, W.
Deposit date:2020-11-01
Release date:2021-11-10
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.197 Å)
Cite:Structure of human adenylate kinase 1 mutant-R128W.
To Be Published
7DY6
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BU of 7dy6 by Molmil
A refined cryo-EM structure of an Escherichia coli RNAP-promoter open complex (RPo) with SspA
Descriptor: DNA (63-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Lin, W.
Deposit date:2021-01-20
Release date:2021-11-17
Method:ELECTRON MICROSCOPY (3.68 Å)
Cite:A unique binding between SspA and RNAP beta' NTH across low-GC Gram-negative bacteria facilitates SspA-mediated transcription regulation.
Biochem.Biophys.Res.Commun., 583, 2021
8HIH
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BU of 8hih by Molmil
Cryo-EM structure of Mycobacterium tuberculosis transcription initiation complex with transcription factor GlnR
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Lin, W, Shi, J, Xu, J.C.
Deposit date:2022-11-20
Release date:2023-06-07
Method:ELECTRON MICROSCOPY (3.66 Å)
Cite:Structural insights into the transcription activation mechanism of the global regulator GlnR from actinobacteria.
Proc.Natl.Acad.Sci.USA, 120, 2023
8HML
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BU of 8hml by Molmil
Co-crystal structure of the C terminal DNA binding domain of Saccharopolyspora erythraea GlnR in complex with its conserved promoter DNA in 2.95 Angstrom resolution
Descriptor: DNA (5'-D(*AP*CP*GP*TP*AP*AP*CP*AP*TP*CP*GP*CP*GP*GP*TP*AP*AP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*TP*TP*AP*CP*CP*GP*CP*GP*AP*TP*GP*TP*TP*AP*CP*GP*T)-3'), DNA-binding response OmpR family regulator
Authors:Lin, W, Xu, J.C.
Deposit date:2022-12-04
Release date:2023-06-07
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structural insights into the transcription activation mechanism of the global regulator GlnR from actinobacteria.
Proc.Natl.Acad.Sci.USA, 120, 2023
7EQL
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BU of 7eql by Molmil
Crystal structure of (+)-pulegone reductase from Mentha piperita
Descriptor: (+)-pulegone reductase
Authors:Lin, W.
Deposit date:2021-05-03
Release date:2021-09-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Functional Characterization and Structural Insights Into Stereoselectivity of Pulegone Reductase in Menthol Biosynthesis.
Front Plant Sci, 12, 2021
7F75
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BU of 7f75 by Molmil
Cryo-EM structure of Spx-dependent transcription activation complex
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Lin, W, Feng, Y, Shi, J.
Deposit date:2021-06-28
Release date:2021-10-13
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural basis of transcription activation by the global regulator Spx.
Nucleic Acids Res., 49, 2021

 

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