1SEM
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1LLI
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![BU of 1lli by Molmil](/molmil-images/mine/1lli) | THE CRYSTAL STRUCTURE OF A MUTANT PROTEIN WITH ALTERED BUT IMPROVED HYDROPHOBIC CORE PACKING | Descriptor: | DNA (5'-D(*AP*AP*TP*AP*CP*CP*AP*CP*TP*GP*GP*CP*GP*GP*TP*GP*A P*TP*AP*T)-3'), DNA (5'-D(*TP*AP*TP*AP*TP*CP*AP*CP*CP*GP*CP*CP*AP*GP*TP*GP*G P*TP*AP*T)-3'), PROTEIN (LAMBDA REPRESSOR) | Authors: | Lim, W.A, Hodel, A, Sauer, R.T, Richards, F.M. | Deposit date: | 1994-03-25 | Release date: | 1994-08-31 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The crystal structure of a mutant protein with altered but improved hydrophobic core packing. Proc.Natl.Acad.Sci.USA, 91, 1994
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1MKE
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![BU of 1mke by Molmil](/molmil-images/mine/1mke) | Structure of the N-WASP EVH1 Domain-WIP complex | Descriptor: | Fusion protein consisting of Wiskott-Aldrich syndrome protein interacting protein (WIP), GSGSG linker, and Neural Wiskott-Aldrich syndrome protein (N-WASP) | Authors: | Volkman, B.F, Prehoda, K.E, Scott, J.A, Peterson, F.C, Lim, W.A. | Deposit date: | 2002-08-29 | Release date: | 2002-12-04 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure of the N-WASP EVH1 Domain-WIP Complex. Insight into the
Molecular Basis of Wiskott-Aldrich Syndrome. Cell(Cambridge,Mass.), 111, 2002
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3QBV
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![BU of 3qbv by Molmil](/molmil-images/mine/3qbv) | Structure of designed orthogonal interaction between CDC42 and nucleotide exchange domains of intersectin | Descriptor: | Cell division control protein 42 homolog, GUANOSINE-5'-DIPHOSPHATE, Intersectin-1 | Authors: | Kapp, G.T, Remenyi, A, Lim, W.A, Kortemme, T. | Deposit date: | 2011-01-14 | Release date: | 2012-02-08 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Control of protein signaling using a computationally designed GTPase/GEF orthogonal pair. Proc.Natl.Acad.Sci.USA, 109, 2012
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3SEM
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![BU of 3sem by Molmil](/molmil-images/mine/3sem) | SEM5 SH3 DOMAIN COMPLEXED WITH PEPTOID INHIBITOR | Descriptor: | SEX MUSCLE ABNORMAL PROTEIN 5, SH3 PEPTOID INHIBITOR | Authors: | Nguyen, J.T, Turck, C.W, Cohen, F.E, Zuckermann, R.N, Lim, W.A. | Deposit date: | 1998-11-02 | Release date: | 1999-01-06 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Exploiting the basis of proline recognition by SH3 and WW domains: design of N-substituted inhibitors. Science, 282, 1998
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3FZE
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![BU of 3fze by Molmil](/molmil-images/mine/3fze) | Structure of the 'minimal scaffold' (ms) domain of Ste5 that cocatalyzes Fus3 phosphorylation by Ste7 | Descriptor: | Protein STE5 | Authors: | Good, M.C, Tang, G, Singleton, J, Remenyi, A, Lim, W.A. | Deposit date: | 2009-01-25 | Release date: | 2009-03-31 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.601 Å) | Cite: | The Ste5 scaffold directs mating signaling by catalytically unlocking the Fus3 MAP kinase for activation. Cell(Cambridge,Mass.), 136, 2009
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2SEM
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![BU of 2sem by Molmil](/molmil-images/mine/2sem) | SEM5 SH3 DOMAIN COMPLEXED WITH PEPTOID INHIBITOR | Descriptor: | PROTEIN (SEX MUSCLE ABNORMAL PROTEIN 5), PROTEIN (SH3 PEPTOID INHIBITOR) | Authors: | Nguyen, J.T, Turck, C.W, Cohen, F.E, Zuckermann, R.N, Lim, W.A. | Deposit date: | 1998-11-02 | Release date: | 1999-01-06 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Exploiting the basis of proline recognition by SH3 and WW domains: design of N-substituted inhibitors. Science, 282, 1998
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4F2H
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2B9H
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![BU of 2b9h by Molmil](/molmil-images/mine/2b9h) | Crystal structure of Fus3 with a docking motif from Ste7 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Mitogen-activated protein kinase FUS3, ... | Authors: | Remenyi, A, Good, M.C, Bhattacharyya, R.P, Lim, W.A. | Deposit date: | 2005-10-11 | Release date: | 2006-01-03 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | The role of docking interactions in mediating signaling input, output, and discrimination in the yeast MAPK network. Mol.Cell, 20, 2005
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2B9F
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![BU of 2b9f by Molmil](/molmil-images/mine/2b9f) | Crystal structure of non-phosphorylated Fus3 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Mitogen-activated protein kinase FUS3 | Authors: | Remenyi, A, Good, M.C, Bhattacharyya, R.P, Lim, W.A. | Deposit date: | 2005-10-11 | Release date: | 2006-01-03 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The role of docking interactions in mediating signaling input, output, and discrimination in the yeast MAPK network. Mol.Cell, 20, 2005
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2B9J
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![BU of 2b9j by Molmil](/molmil-images/mine/2b9j) | Crystal structure of Fus3 with a docking motif from Far1 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Cyclin-dependent kinase inhibitor FAR1, MAGNESIUM ION, ... | Authors: | Remenyi, A, Good, M.C, Bhattacharyya, R.P, Lim, W.A. | Deposit date: | 2005-10-11 | Release date: | 2006-01-03 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The role of docking interactions in mediating signaling input, output, and discrimination in the yeast MAPK network. Mol.Cell, 20, 2005
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2B9I
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![BU of 2b9i by Molmil](/molmil-images/mine/2b9i) | Crystal structure of Fus3 with a docking motif from Msg5 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Mitogen-activated protein kinase FUS3, ... | Authors: | Remenyi, A, Good, M.C, Bhattacharyya, R.P, Lim, W.A. | Deposit date: | 2005-10-11 | Release date: | 2006-01-03 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The role of docking interactions in mediating signaling input, output, and discrimination in the yeast MAPK network. Mol.Cell, 20, 2005
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2F9G
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![BU of 2f9g by Molmil](/molmil-images/mine/2f9g) | Crystal structure of Fus3 phosphorylated on Tyr182 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Mitogen-activated protein kinase FUS3 | Authors: | Bhattacharyya, R.P, Remenyi, A, Good, M.C, Bashor, C.J, Falick, A.M, Lim, W.A. | Deposit date: | 2005-12-05 | Release date: | 2006-11-14 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The Ste5 scaffold allosterically modulates signaling output of the yeast mating pathway. Science, 311, 2006
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2FA2
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![BU of 2fa2 by Molmil](/molmil-images/mine/2fa2) | Crystal structure of Fus3 without a peptide from Ste5 | Descriptor: | Mitogen-activated protein kinase FUS3, THIOCYANATE ION | Authors: | Bhattacharyya, R.P, Remenyi, A, Good, M.C, Bashor, C.J, Falick, A.M, Lim, W.A. | Deposit date: | 2005-12-06 | Release date: | 2006-03-28 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | The Ste5 scaffold allosterically modulates signaling output of the yeast mating pathway Science, 311, 2006
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1QAU
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![BU of 1qau by Molmil](/molmil-images/mine/1qau) | UNEXPECTED MODES OF PDZ DOMAIN SCAFFOLDING REVEALED BY STRUCTURE OF NNOS-SYNTROPHIN COMPLEX | Descriptor: | NEURONAL NITRIC OXIDE SYNTHASE (RESIDUES 1-130) | Authors: | Hillier, B.J, Christopherson, K.S, Prehoda, K.E, Bredt, D.S, Lim, W.A. | Deposit date: | 1999-03-29 | Release date: | 1999-05-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Unexpected modes of PDZ domain scaffolding revealed by structure of nNOS-syntrophin complex. Science, 284, 1999
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1QAV
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![BU of 1qav by Molmil](/molmil-images/mine/1qav) | Unexpected Modes of PDZ Domain Scaffolding Revealed by Structure of NNOS-Syntrophin Complex | Descriptor: | ALPHA-1 SYNTROPHIN (RESIDUES 77-171), NEURONAL NITRIC OXIDE SYNTHASE (RESIDUES 1-130) | Authors: | Hillier, B.J, Christopherson, K.S, Prehoda, K.E, Bredt, D.S, Lim, W.A. | Deposit date: | 1999-03-30 | Release date: | 1999-05-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Unexpected modes of PDZ domain scaffolding revealed by structure of nNOS-syntrophin complex. Science, 284, 1999
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1EVH
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1ZL8
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![BU of 1zl8 by Molmil](/molmil-images/mine/1zl8) | NMR structure of L27 heterodimer from C. elegans Lin-7 and H. sapiens Lin-2 scaffold proteins | Descriptor: | LIN-7, Peripheral plasma membrane protein CASK | Authors: | Petrosky, K.Y, Ou, H.D, Lohr, F, Dotsch, V, Lim, W.A. | Deposit date: | 2005-05-05 | Release date: | 2005-09-13 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | A General Model for Preferential Hetero-oligomerization of LIN-2/7 Domains: Mechanism Underlying Directed Assembly of Supramolecular Signaling Complexes J.Biol.Chem., 280, 2005
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1B07
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![BU of 1b07 by Molmil](/molmil-images/mine/1b07) | CRK SH3 DOMAIN COMPLEXED WITH PEPTOID INHIBITOR | Descriptor: | PHENYLETHANE, PROTEIN (PROTO-ONCOGENE CRK (CRK)), PROTEIN (SH3 PEPTOID INHIBITOR) | Authors: | Nguyen, J.T, Turck, C.W, Cohen, F.E, Zuckermann, R.N, Lim, W.A. | Deposit date: | 1998-11-17 | Release date: | 1999-01-06 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Exploiting the basis of proline recognition by SH3 and WW domains: design of N-substituted inhibitors. Science, 282, 1998
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1KJW
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![BU of 1kjw by Molmil](/molmil-images/mine/1kjw) | SH3-Guanylate Kinase Module from PSD-95 | Descriptor: | POSTSYNAPTIC DENSITY PROTEIN 95, SULFATE ION | Authors: | McGee, A.W, Dakoji, S.R, Olsen, O, Bredt, D.S, Lim, W.A, Prehoda, K.E. | Deposit date: | 2001-12-05 | Release date: | 2002-01-09 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of the SH3-Guanylate Kinase Module from PSD-95 Suggests a Mechanism for Regulated Assembly of MAGUK Scaffolding Proteins Mol.Cell, 8, 2001
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