1HYR
 
 | |
4EMT
 | | Crystal Structure of human STING bound to c-di-GMP | | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CALCIUM ION, Transmembrane protein 173 | | Authors: | Li, P. | | Deposit date: | 2012-04-12 | | Release date: | 2012-06-13 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structure of STING bound to cyclic di-GMP reveals the mechanism of cyclic dinucleotide recognition by the immune system.
Nat.Struct.Mol.Biol., 19, 2012
|
|
4EMU
 | | Crystal structure of ligand free human STING | | Descriptor: | CALCIUM ION, Transmembrane protein 173 | | Authors: | Li, P. | | Deposit date: | 2012-04-12 | | Release date: | 2012-06-13 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structure of STING bound to cyclic di-GMP reveals the mechanism of cyclic dinucleotide recognition by the immune system.
Nat.Struct.Mol.Biol., 19, 2012
|
|
5JEJ
 | | Phosphorylated STING in complex with IRF-3 CTD | | Descriptor: | Interferon regulatory factor 3, Stimulator of interferon genes protein | | Authors: | Li, P, Shu, C. | | Deposit date: | 2016-04-18 | | Release date: | 2016-06-15 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural basis for concerted recruitment and activation of IRF-3 by innate immune adaptor proteins.
Proc.Natl.Acad.Sci.USA, 113, 2016
|
|
3U9M
 | | Structure of reduced human FBXL5 hemerythrin like domain | | Descriptor: | F-box/LRR-repeat protein 5, FE (III) ION | | Authors: | Li, P. | | Deposit date: | 2011-10-19 | | Release date: | 2012-02-22 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | The Structural Basis of Iron Sensing by the Human F-box Protein FBXL5.
Chembiochem, 13, 2012
|
|
1J4I
 | | crystal structure analysis of the FKBP12 complexed with 000308 small molecule | | Descriptor: | 4-METHYL-2-{[4-(TOLUENE-4-SULFONYL)-THIOMORPHOLINE-3-CARBONYL]-AMINO}-PENTANOIC ACID, FKBP12 | | Authors: | Li, P, Ding, Y, Wang, L, Wu, B, Shu, C, Li, S, Shen, B, Rao, Z. | | Deposit date: | 2001-09-30 | | Release date: | 2003-06-03 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Design and structure-based study of new potential FKBP12 inhibitors.
Biophys.J., 85, 2003
|
|
6LKA
 | | Crystal Structure of EV71-3C protease with a Novel Macrocyclic Compounds | | Descriptor: | 3C proteinase, ~{N}-[(2~{S})-1-[[(2~{S},3~{S},6~{S},7~{Z},12~{E})-4,9-bis(oxidanylidene)-6-[[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]methyl]-2-phenyl-1,10-dioxa-5-azacyclopentadeca-7,12-dien-3-yl]amino]-3-methyl-1-oxidanylidene-butan-2-yl]-5-methyl-1,2-oxazole-3-carboxamide | | Authors: | Li, P, Wu, S.Q, Xiao, T.Y.C, Li, Y.L, Su, Z.M, Hao, F, Hu, G.P, Hu, J, Lin, F.S, Chen, X.S, Gu, Z.X, He, H.Y, Li, J, Chen, S.H. | | Deposit date: | 2019-12-18 | | Release date: | 2020-06-17 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.033 Å) | | Cite: | Design, synthesis, and evaluation of a novel macrocyclic anti-EV71 agent.
Bioorg.Med.Chem., 28, 2020
|
|
1J4H
 | | crystal structure analysis of the FKBP12 complexed with 000107 small molecule | | Descriptor: | 3-PHENYL-2-{[4-(TOLUENE-4-SULFONYL)-THIOMORPHOLINE-3-CARBONYL]-AMINO}-PROPIONIC ACID ETHYL ESTER, FKBP12 | | Authors: | Li, P, Ding, Y, Wang, L, Wu, B, Shu, C, Li, S, Shen, B, Rao, Z. | | Deposit date: | 2001-09-30 | | Release date: | 2003-06-03 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Design and structure-based study of new potential FKBP12 inhibitors.
Biophys.J., 85, 2003
|
|
7OP1
 | | Cryo-EM structure of P5B-ATPase E2PiAlF/SPM | | Descriptor: | Cation-transporting ATPase, MAGNESIUM ION, SPERMINE, ... | | Authors: | Li, P, Gourdon, P. | | Deposit date: | 2021-05-28 | | Release date: | 2021-06-30 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structure and transport mechanism of P5B-ATPases.
Nat Commun, 12, 2021
|
|
7OP8
 | | Cryo-EM structure of P5B-ATPase E2Pinhibit | | Descriptor: | BERYLLIUM TRIFLUORIDE ION, Cation-transporting ATPase, MAGNESIUM ION | | Authors: | Li, P, Gourdon, P. | | Deposit date: | 2021-05-31 | | Release date: | 2021-06-30 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Structure and transport mechanism of P5B-ATPases.
Nat Commun, 12, 2021
|
|
7OP5
 | | Cryo-EM structure of P5B-ATPase E2P | | Descriptor: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, P5B-ATPase | | Authors: | Li, P, Gourdon, P. | | Deposit date: | 2021-05-29 | | Release date: | 2021-06-30 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structure and transport mechanism of P5B-ATPases.
Nat Commun, 12, 2021
|
|
8OP4
 | | Cryo-EM structure of P5A-ATPase CtSpf1 (E1-ATP state) | | Descriptor: | Cation-transporting ATPase-like protein, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | Authors: | Li, P, Gourdon, P. | | Deposit date: | 2023-04-06 | | Release date: | 2024-10-16 | | Last modified: | 2024-11-20 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | The structure and function of P5A-ATPases.
Nat Commun, 15, 2024
|
|
8OP5
 | |
8OP8
 | |
8OP3
 | |
8OP6
 | |
8OP7
 | |
7PGE
 | | copper transporter PcoB | | Descriptor: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, Copper resistance protein B, LAURYL DIMETHYLAMINE-N-OXIDE, ... | | Authors: | Li, P, Gourdon, P.E. | | Deposit date: | 2021-08-13 | | Release date: | 2022-07-06 | | Last modified: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | PcoB is a defense outer membrane protein that facilitates cellular uptake of copper.
Protein Sci., 31, 2022
|
|
7PQX
 | |
7PRO
 | |
7PSD
 | |
7PRU
 | |
7PR1
 | |
7OP3
 | | Cryo-EM structure of P5B-ATPase E2PiSPM | | Descriptor: | Cation-transporting ATPase, SPERMINE | | Authors: | Li, P, Gronberg, C, Wang, K.T, Salustros, N, Gourdon, P.E. | | Deposit date: | 2021-05-28 | | Release date: | 2021-06-30 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Structure and transport mechanism of P5B-ATPases.
Nat Commun, 12, 2021
|
|
3EQT
 | |
