3LRN
 
 | | Crystal structure of human RIG-I CTD bound to a 14 bp GC 5' ppp dsRNA | | Descriptor: | Probable ATP-dependent RNA helicase DDX58, RNA (5'-R(*(GTP)P*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*C)-3'), ZINC ION | | Authors: | Li, P. | | Deposit date: | 2010-02-11 | | Release date: | 2010-06-02 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | The Structural Basis of 5' Triphosphate Double-Stranded RNA Recognition by RIG-I C-Terminal Domain.
Structure, 18, 2010
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9J61
 | | Crystal structure of a cyclodipeptide synthase from Streptomyces sapporonensis | | Descriptor: | 1,2-ETHANEDIOL, Cyclodipeptide synthase, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Li, P, Ren, Y, He, J, Wu, S, Wang, J, Tang, G, Fang, P. | | Deposit date: | 2024-08-14 | | Release date: | 2024-12-04 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal Structure and Mutagenesis of an XYP Subfamily Cyclodipeptide Synthase Reveal Key Determinants of Enzyme Activity and Substrate Specificity.
Biochemistry, 63, 2024
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5V5F
 | | Crystal structure of RICE1 (PNT2) | | Descriptor: | At3g11770 | | Authors: | Li, P. | | Deposit date: | 2017-03-14 | | Release date: | 2017-09-13 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.945 Å) | | Cite: | RISC-interacting clearing 3'- 5' exoribonucleases (RICEs) degrade uridylated cleavage fragments to maintain functional RISC in Arabidopsis thaliana.
Elife, 6, 2017
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7OP8
 | | Cryo-EM structure of P5B-ATPase E2Pinhibit | | Descriptor: | BERYLLIUM TRIFLUORIDE ION, Cation-transporting ATPase, MAGNESIUM ION | | Authors: | Li, P, Gourdon, P. | | Deposit date: | 2021-05-31 | | Release date: | 2021-06-30 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Structure and transport mechanism of P5B-ATPases.
Nat Commun, 12, 2021
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7OP5
 | | Cryo-EM structure of P5B-ATPase E2P | | Descriptor: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, P5B-ATPase | | Authors: | Li, P, Gourdon, P. | | Deposit date: | 2021-05-29 | | Release date: | 2021-06-30 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structure and transport mechanism of P5B-ATPases.
Nat Commun, 12, 2021
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7OP1
 | | Cryo-EM structure of P5B-ATPase E2PiAlF/SPM | | Descriptor: | Cation-transporting ATPase, MAGNESIUM ION, SPERMINE, ... | | Authors: | Li, P, Gourdon, P. | | Deposit date: | 2021-05-28 | | Release date: | 2021-06-30 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structure and transport mechanism of P5B-ATPases.
Nat Commun, 12, 2021
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1J4I
 | | crystal structure analysis of the FKBP12 complexed with 000308 small molecule | | Descriptor: | 4-METHYL-2-{[4-(TOLUENE-4-SULFONYL)-THIOMORPHOLINE-3-CARBONYL]-AMINO}-PENTANOIC ACID, FKBP12 | | Authors: | Li, P, Ding, Y, Wang, L, Wu, B, Shu, C, Li, S, Shen, B, Rao, Z. | | Deposit date: | 2001-09-30 | | Release date: | 2003-06-03 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Design and structure-based study of new potential FKBP12 inhibitors.
Biophys.J., 85, 2003
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1J4H
 | | crystal structure analysis of the FKBP12 complexed with 000107 small molecule | | Descriptor: | 3-PHENYL-2-{[4-(TOLUENE-4-SULFONYL)-THIOMORPHOLINE-3-CARBONYL]-AMINO}-PROPIONIC ACID ETHYL ESTER, FKBP12 | | Authors: | Li, P, Ding, Y, Wang, L, Wu, B, Shu, C, Li, S, Shen, B, Rao, Z. | | Deposit date: | 2001-09-30 | | Release date: | 2003-06-03 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Design and structure-based study of new potential FKBP12 inhibitors.
Biophys.J., 85, 2003
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7OP3
 | | Cryo-EM structure of P5B-ATPase E2PiSPM | | Descriptor: | Cation-transporting ATPase, SPERMINE | | Authors: | Li, P, Gronberg, C, Wang, K.T, Salustros, N, Gourdon, P.E. | | Deposit date: | 2021-05-28 | | Release date: | 2021-06-30 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Structure and transport mechanism of P5B-ATPases.
Nat Commun, 12, 2021
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7EOD
 | | MITF HLHLZ Delta AKE | | Descriptor: | GLYCEROL, Isoform M1 of Microphthalmia-associated transcription factor | | Authors: | Li, P, Liu, Z, Fang, P, Wang, J. | | Deposit date: | 2021-04-22 | | Release date: | 2022-04-27 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | A unique hyperdynamic dimer interface permits small molecule perturbation of the melanoma oncoprotein MITF for melanoma therapy.
Cell Res., 33, 2023
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7PGE
 | | copper transporter PcoB | | Descriptor: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, Copper resistance protein B, LAURYL DIMETHYLAMINE-N-OXIDE, ... | | Authors: | Li, P, Gourdon, P.E. | | Deposit date: | 2021-08-13 | | Release date: | 2022-07-06 | | Last modified: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | PcoB is a defense outer membrane protein that facilitates cellular uptake of copper.
Protein Sci., 31, 2022
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7PQX
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7PSD
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7PRO
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7PRU
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7PR1
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1HYR
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6O8C
 | | Crystal structure of STING CTT in complex with TBK1 | | Descriptor: | N-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide, Serine/threonine-protein kinase TBK1, Stimulator of interferon genes protein | | Authors: | Li, P, Zhao, B, Du, F. | | Deposit date: | 2019-03-09 | | Release date: | 2019-05-22 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (3.17 Å) | | Cite: | A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1.
Nature, 569, 2019
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6O8B
 | | Crystal structure of STING CTD in complex with TBK1 | | Descriptor: | N-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide, Serine/threonine-protein kinase TBK1, Stimulator of interferon genes protein | | Authors: | Li, P, Zhao, B, Du, F. | | Deposit date: | 2019-03-09 | | Release date: | 2019-05-22 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1.
Nature, 569, 2019
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3EQT
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8OP5
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8OP7
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8OP6
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8OP4
 | | Cryo-EM structure of P5A-ATPase CtSpf1 (E1-ATP state) | | Descriptor: | Cation-transporting ATPase-like protein, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | Authors: | Li, P, Gourdon, P. | | Deposit date: | 2023-04-06 | | Release date: | 2024-10-16 | | Last modified: | 2024-11-20 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | The structure and function of P5A-ATPases.
Nat Commun, 15, 2024
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8OP8
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