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PDB: 215 件

7SH0
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CRYSTAL STRUCTURE OF ENDOPLASMIC RETICULUM AMINOPEPTIDASE 2 (ERAP2) COMPLEX WITH A HIGHLY SELECTIVE AND POTENT SMALL MOLECULE
分子名称: (2S)-N-hydroxy-3-(4-methoxyphenyl)-2-[4-({[5-(pyridin-2-yl)thiophene-2-sulfonyl]amino}methyl)-1H-1,2,3-triazol-1-yl]propanamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Li, L, Bouvier, M.
登録日2021-10-07
公開日2022-07-20
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Discovery of the First Selective Nanomolar Inhibitors of ERAP2 by Kinetic Target-Guided Synthesis.
Angew.Chem.Int.Ed.Engl., 61, 2022
3DAN
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BU of 3dan by Molmil
Crystal Structure of Allene oxide synthase
分子名称: Cytochrome P450 74A2, PROTOPORPHYRIN IX CONTAINING FE
著者Li, L, Wang, X.
登録日2008-05-29
公開日2008-09-23
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Modes of heme binding and substrate access for cytochrome P450 CYP74A revealed by crystal structures of allene oxide synthase.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3DBM
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BU of 3dbm by Molmil
Crystal Structure of Allene oxide synthase
分子名称: (9E,11E,13S)-13-hydroxyoctadeca-9,11-dienoic acid, Cytochrome P450 74A2, PROTOPORPHYRIN IX CONTAINING FE
著者Li, L, Wang, X.
登録日2008-06-01
公開日2008-09-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Modes of heme binding and substrate access for cytochrome P450 CYP74A revealed by crystal structures of allene oxide synthase.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3DAM
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BU of 3dam by Molmil
Crystal Structure of Allene oxide synthase
分子名称: Cytochrome P450 74A2, PROTOPORPHYRIN IX CONTAINING FE
著者Li, L, Wang, X.
登録日2008-05-29
公開日2008-09-23
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Modes of heme binding and substrate access for cytochrome P450 CYP74A revealed by crystal structures of allene oxide synthase.
Proc.Natl.Acad.Sci.Usa, 105, 2008
5ZX3
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BU of 5zx3 by Molmil
Mycobacterium tuberculosis RNA polymerase holoenzyme with ECF sigma factor sigma H
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Li, L, Zhang, Y.
登録日2018-05-17
公開日2019-03-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.751 Å)
主引用文献Structural basis for transcription initiation by bacterial ECF sigma factors.
Nat Commun, 10, 2019
5ZX2
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Mycobacterium tuberculosis RNA polymerase transcription initiation complex with ECF sigma factor sigma H and 7nt RNA
分子名称: DNA (47-MER), DNA (48-MER), DNA-directed RNA polymerase subunit alpha, ...
著者Li, L, Zhang, Y.
登録日2018-05-17
公開日2019-03-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for transcription initiation by bacterial ECF sigma factors.
Nat Commun, 10, 2019
8FNZ
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BU of 8fnz by Molmil
Acetylated tau repeat 1 and 2 fragment (AcR1R2)
分子名称: Microtubule-associated protein tau, acetylated repeat 1 and 2 fragment
著者Li, L, Nguyen, A.B, Mullapudi, V, Joachimiak, L.
登録日2022-12-29
公開日2023-06-28
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3.88 Å)
主引用文献Disease-associated patterns of acetylation stabilize tau fibril formation.
Structure, 31, 2023
3ZIU
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BU of 3ziu by Molmil
Crystal structure of Mycoplasma mobile Leucyl-tRNA Synthetase with Leu-AMS in the active site
分子名称: 5'-O-(L-leucylsulfamoyl)adenosine, GLYCEROL, LEUCYL-TRNA SYNTHETASE
著者Li, L, Palencia, A, Lukk, T, Li, Z, Luthey-Schulten, Z.A, Cusack, S, Martinis, S.A, Boniecki, M.T.
登録日2013-01-10
公開日2013-02-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Leucyl-tRNA Synthetase Editing Domain Functions as a Molecular Rheostat to Control Codon Ambiguity in Mycoplasma Pathogens.
Proc.Natl.Acad.Sci.USA, 110, 2013
3B9O
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BU of 3b9o by Molmil
long-chain alkane monooxygenase (LadA) in complex with coenzyme FMN
分子名称: Alkane monooxygenase, FLAVIN MONONUCLEOTIDE
著者Li, L, Yang, W, Xu, F, Bartlam, M, Rao, Z.
登録日2007-11-06
公開日2008-01-15
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of long-chain alkane monooxygenase (LadA) in complex with coenzyme FMN: unveiling the long-chain alkane hydroxylase
J.Mol.Biol., 376, 2008
3B9N
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Crystal structure of long-chain alkane monooxygenase (LadA)
分子名称: Alkane monooxygenase
著者Li, L, Yang, W, Xu, F, Bartlam, M, Rao, Z.
登録日2007-11-06
公開日2008-01-15
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of long-chain alkane monooxygenase (LadA) in complex with coenzyme FMN: unveiling the long-chain alkane hydroxylase
J.Mol.Biol., 376, 2008
5NKM
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BU of 5nkm by Molmil
SMG8-SMG9 complex
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, ...
著者Li, L, Basquin, J, Conti, E.
登録日2017-03-31
公開日2017-04-19
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.493 Å)
主引用文献Structure of a SMG8-SMG9 complex identifies a G-domain heterodimer in the NMD effector proteins.
RNA, 23, 2017
5NKK
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BU of 5nkk by Molmil
SMG8-SMG9 complex GDP bound
分子名称: 1,2-ETHANEDIOL, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Li, L, Basquin, J, Conti, E.
登録日2017-03-31
公開日2017-04-19
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Structure of a SMG8-SMG9 complex identifies a G-domain heterodimer in the NMD effector proteins.
RNA, 23, 2017
1QVO
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BU of 1qvo by Molmil
STRUCTURES OF HLA-A*1101 IN COMPLEX WITH IMMUNODOMINANT NONAMER AND DECAMER HIV-1 EPITOPES CLEARLY REVEAL THE PRESENCE OF A MIDDLE ANCHOR RESIDUE
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-11 alpha chain, ...
著者Li, L, McNicholl, J.M, Bouvier, M.
登録日2003-08-28
公開日2004-06-01
最終更新日2020-02-19
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Structures of HLA-A*1101 complexed with immunodominant nonamer and decamer HIV-1 epitopes clearly reveal the presence of a middle, secondary anchor residue.
J.Immunol., 172, 2004
2PQ6
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BU of 2pq6 by Molmil
Crystal structure of Medicago truncatula UGT85H2- Insights into the structural basis of a multifunctional (Iso) flavonoid glycosyltransferase
分子名称: UDP-glucuronosyl/UDP-glucosyltransferase
著者Li, L, Modolo, L.V, Escamilla-Trevino, L.L, Wang, X.
登録日2007-05-01
公開日2007-07-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of Medicago truncatula UGT85H2 - Insights into the Structural Basis of a Multifunctional (Iso)flavonoid Glycosyltransferase.
J.Mol.Biol., 370, 2007
6P27
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BU of 6p27 by Molmil
Structure of a nested set of N-terminally extended MHC I-peptides provides novel insights into antigen processing and presentation
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-8 alpha chain, ...
著者Li, L, Batliwala, M, Bouvier, M.
登録日2019-05-21
公開日2019-10-16
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.593 Å)
主引用文献ERAP1 enzyme-mediated trimming and structural analyses of MHC I-bound precursor peptides yield novel insights into antigen processing and presentation.
J.Biol.Chem., 294, 2019
6P2C
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BU of 6p2c by Molmil
Structure of a nested set of N-terminally extended MHC I-peptides provides novel insights into antigen processing and presentation
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-8 alpha chain, ...
著者Li, L, Batliwala, M, Bouvier, M.
登録日2019-05-21
公開日2019-10-16
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.396 Å)
主引用文献ERAP1 enzyme-mediated trimming and structural analyses of MHC I-bound precursor peptides yield novel insights into antigen processing and presentation.
J.Biol.Chem., 294, 2019
6P2S
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BU of 6p2s by Molmil
Structure of a nested set of N-terminally extended MHC I-peptides provide novel insights into antigen processing and presentation
分子名称: Beta-2-microglobulin, MHC I-peptide, MHC class I antigen
著者Li, L, Batliwala, M, Bouvier, M.
登録日2019-05-22
公開日2019-10-16
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献ERAP1 enzyme-mediated trimming and structural analyses of MHC I-bound precursor peptides yield novel insights into antigen processing and presentation.
J.Biol.Chem., 294, 2019
6P2F
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BU of 6p2f by Molmil
Structure of a nested set of N-terminally extended MHC I-peptides provides novel insights into antigen processing and presentation
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-8 alpha chain, ...
著者Li, L, Batliwala, M, Bouvier, M.
登録日2019-05-21
公開日2019-10-16
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.482 Å)
主引用文献ERAP1 enzyme-mediated trimming and structural analyses of MHC I-bound precursor peptides yield novel insights into antigen processing and presentation.
J.Biol.Chem., 294, 2019
6P23
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BU of 6p23 by Molmil
Structure of a nested set of N-terminally extended MHC I-peptides provide novel insights into antigen processing presentation
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-8 alpha chain, ...
著者Li, L, Batliwala, M, Bouvier, M.
登録日2019-05-20
公開日2019-10-16
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.595 Å)
主引用文献ERAP1 enzyme-mediated trimming and structural analyses of MHC I-bound precursor peptides yield novel insights into antigen processing and presentation.
J.Biol.Chem., 294, 2019
3C6D
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BU of 3c6d by Molmil
The pseudo-atomic structure of dengue immature virus
分子名称: Polyprotein, prM
著者Li, L.
登録日2008-02-04
公開日2008-04-08
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (12.5 Å)
主引用文献The flavivirus precursor membrane-envelope protein complex: structure and maturation
Science, 319, 2008
3C5X
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BU of 3c5x by Molmil
Crystal structure of the precursor membrane protein- envelope protein heterodimer from the dengue 2 virus at low pH
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein E, beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]alpha-D-altropyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Li, L.
登録日2008-02-01
公開日2008-04-08
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The flavivirus precursor membrane-envelope protein complex: structure and maturation.
Science, 319, 2008
3C6E
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BU of 3c6e by Molmil
Crystal structure of the precursor membrane protein- envelope protein heterodimer from the dengue 2 virus at neutral pH
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein E, ...
著者Li, L.
登録日2008-02-04
公開日2008-04-08
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The flavivirus precursor membrane-envelope protein complex: structure and maturation.
Science, 319, 2008
3D38
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BU of 3d38 by Molmil
Crystal structure of new trigonal form of photosynthetic reaction center from Blastochloris viridis. Crystals grown in microfluidics by detergent capture.
分子名称: 15-cis-1,2-dihydroneurosporene, BACTERIOCHLOROPHYLL B, BACTERIOPHEOPHYTIN B, ...
著者Li, L, Nachtergaele, S.H.M, Seddon, A.M, Tereshko, V, Ponomarenko, N, Ismagilov, R.F, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D)
登録日2008-05-09
公開日2008-07-08
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.21 Å)
主引用文献Simple host-guest chemistry to modulate the process of concentration and crystallization of membrane proteins by detergent capture in a microfluidic device.
J.Am.Chem.Soc., 130, 2008
6JCX
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Mycobacterium tuberculosis transcription initiation complex with ECF sigma factor sigma H and 6nt RNA
分子名称: DNA (5'-D(*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*GP*T)-3'), DNA (5'-D(*TP*TP*GP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*A)-3'), DNA-directed RNA polymerase subunit alpha, ...
著者Li, L, Zhang, Y.
登録日2019-01-30
公開日2019-05-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.903 Å)
主引用文献Structures and mechanism of transcription initiation by bacterial ECF factors.
Nucleic Acids Res., 47, 2019
6JCY
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Mycobacterium tuberculosis RNA polymerase transcription initiation open complex with a chimeric ECF sigma factor sigH/E
分子名称: DNA (5'-D(*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*GP*T)-3'), DNA (5'-D(*TP*TP*GP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*A)-3'), DNA-directed RNA polymerase subunit alpha, ...
著者Li, L, Zhang, Y.
登録日2019-01-30
公開日2019-05-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.106 Å)
主引用文献Structures and mechanism of transcription initiation by bacterial ECF factors.
Nucleic Acids Res., 47, 2019

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