8EYX
 
 | | Cryo-EM structure of 4 insulins bound full-length mouse IR mutant with physically decoupled alpha CTs (C684S/C685S/C687S; denoted as IR-3CS) Asymmetric conformation 1 | | Descriptor: | Insulin, Insulin receptor | | Authors: | Li, J, Wu, J.Y, Hall, C, Bai, X.C, Choi, E. | | Deposit date: | 2022-10-29 | | Release date: | 2022-11-09 | | Last modified: | 2022-12-07 | | Method: | ELECTRON MICROSCOPY (4.5 Å) | | Cite: | Molecular basis for the role of disulfide-linked alpha CTs in the activation of insulin-like growth factor 1 receptor and insulin receptor.
Elife, 11, 2022
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3R93
 | | Crystal structure of the chromo domain of M-phase phosphoprotein 8 bound to H3K9Me3 peptide | | Descriptor: | H3K9Me3 peptide, M-phase phosphoprotein 8, UNKNOWN ATOM OR ION | | Authors: | Li, J, Li, Z, Ruan, J, Xu, C, Tong, Y, Pan, P.W, Tempel, W, Crombet, L, Min, J, Zang, J, Structural Genomics Consortium (SGC) | | Deposit date: | 2011-03-24 | | Release date: | 2011-04-06 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.057 Å) | | Cite: | Structural basis for specific binding of human MPP8 chromodomain to histone H3 methylated at lysine 9.
Plos One, 6, 2011
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5ZVH
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8CZP
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6Q2R
 | | Cryo-EM structure of RET/GFRa2/NRTN extracellular complex in the tetrameric form | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GDNF family receptor alpha-2, ... | | Authors: | Li, J, Shang, G.J, Chen, Y.J, Brautigam, C.A, Liou, J, Zhang, X.W, Bai, X.C. | | Deposit date: | 2019-08-08 | | Release date: | 2019-10-02 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (4.3 Å) | | Cite: | Cryo-EM analyses reveal the common mechanism and diversification in the activation of RET by different ligands.
Elife, 8, 2019
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6Q2J
 | | Cryo-EM structure of extracellular dimeric complex of RET/GFRAL/GDF15 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GDNF family receptor alpha-like, ... | | Authors: | Li, J, Shang, G.J, Chen, Y.J, Brautigam, C.A, Liou, J, Zhang, X.W, Bai, X.C. | | Deposit date: | 2019-08-08 | | Release date: | 2019-10-02 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Cryo-EM analyses reveal the common mechanism and diversification in the activation of RET by different ligands.
Elife, 8, 2019
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6Q2S
 | | Cryo-EM structure of RET/GFRa3/ARTN extracellular complex. The 3D refinement was applied with C2 symmetry. | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GDNF family receptor alpha-3, ... | | Authors: | Li, J, Shang, G.J, Chen, Y.J, Brautigam, C.A, Liou, J, Zhang, X.W, Bai, X.C. | | Deposit date: | 2019-08-08 | | Release date: | 2019-10-02 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Cryo-EM analyses reveal the common mechanism and diversification in the activation of RET by different ligands.
Elife, 8, 2019
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6Q2O
 | | Cryo-EM structure of RET/GFRa2/NRTN extracellular complex. The 3D refinement was applied with C2 symmetry. | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GDNF family receptor alpha-2, ... | | Authors: | Li, J, Shang, G.J, Chen, Y.J, Brautigam, C.A, Liou, J, Zhang, X.W, Bai, X.C. | | Deposit date: | 2019-08-08 | | Release date: | 2019-10-02 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (3.65 Å) | | Cite: | Cryo-EM analyses reveal the common mechanism and diversification in the activation of RET by different ligands.
Elife, 8, 2019
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6Q2N
 | | Cryo-EM structure of RET/GFRa1/GDNF extracellular complex | | Descriptor: | CALCIUM ION, GDNF family receptor alpha-1, Glial cell line-derived neurotrophic factor, ... | | Authors: | Li, J, Shang, G.J, Chen, Y.J, Brautigam, C.A, Liou, J, Zhang, X.W, Bai, X.C. | | Deposit date: | 2019-08-08 | | Release date: | 2019-10-02 | | Method: | ELECTRON MICROSCOPY (4.4 Å) | | Cite: | Cryo-EM analyses reveal the common mechanism and diversification in the activation of RET by different ligands.
Elife, 8, 2019
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6WLG
 | | Ints3 C-terminal Domain | | Descriptor: | Integrator complex subunit 3 | | Authors: | Li, J, Ma, X.L, Banerjee, S, Dong, Z.G. | | Deposit date: | 2020-04-20 | | Release date: | 2020-12-02 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (3.111 Å) | | Cite: | Structural basis for multifunctional roles of human Ints3 C-terminal domain.
J.Biol.Chem., 296, 2020
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4EFO
 | | Crystal structure of the ubiquitin-like domain of human TBK1 | | Descriptor: | Serine/threonine-protein kinase TBK1 | | Authors: | Li, J, Li, J, Miyahira, A, Sun, J, Liu, Y, Cheng, G, Liang, H. | | Deposit date: | 2012-03-30 | | Release date: | 2012-06-27 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.769 Å) | | Cite: | Crystal structure of the ubiquitin-like domain of human TBK1.
Protein Cell, 3, 2012
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6XMV
 | | The crystal structure of Neisseria gonorrhoeae DolP (NGO1985) | | Descriptor: | CHLORIDE ION, Hemolysin,Endolysin | | Authors: | Li, J, Peterson Brown, L.E, Reed, R.W, Wierzbicki, I.H, Sikora, A.E, Korotkov, K.V. | | Deposit date: | 2020-06-30 | | Release date: | 2021-11-17 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | The structure and function of a new component of Bam complex in Neisseria
To Be Published
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8I24
 | | Clostridium thermocellum RNA polymerase transcription open complex with SigI6 and its promoter | | Descriptor: | DNA (80-mer), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | Authors: | Li, J, Zhang, H, Li, D, Feng, Y, Zhu, P. | | Deposit date: | 2023-01-13 | | Release date: | 2023-10-11 | | Last modified: | 2023-11-01 | | Method: | ELECTRON MICROSCOPY (3.36 Å) | | Cite: | Structure of the transcription open complex of distinct sigma I factors.
Nat Commun, 14, 2023
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4Y7K
 | | Structure of an archaeal mechanosensitive channel in closed state | | Descriptor: | Large conductance mechanosensitive channel protein,Riboflavin synthase | | Authors: | Li, J, Liu, Z. | | Deposit date: | 2015-02-15 | | Release date: | 2015-08-26 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Mechanical coupling of the multiple structural elements of the large-conductance mechanosensitive channel during expansion
Proc.Natl.Acad.Sci.USA, 112, 2015
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8I23
 | | Clostridium thermocellum RNA polymerase transcription open complex with SigI1 and its promoter | | Descriptor: | DNA (80-mer), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | Authors: | Li, J, Zhang, H, Li, D, Feng, Y, Zhu, P. | | Deposit date: | 2023-01-13 | | Release date: | 2023-10-11 | | Last modified: | 2023-11-01 | | Method: | ELECTRON MICROSCOPY (3.03 Å) | | Cite: | Structure of the transcription open complex of distinct sigma I factors.
Nat Commun, 14, 2023
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4Y7J
 | | Structure of an archaeal mechanosensitive channel in expanded state | | Descriptor: | Large conductance mechanosensitive channel protein,Riboflavin synthase, nonyl beta-D-glucopyranoside | | Authors: | Li, J, Liu, Z. | | Deposit date: | 2015-02-15 | | Release date: | 2015-08-26 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (4.1 Å) | | Cite: | Mechanical coupling of the multiple structural elements of the large-conductance mechanosensitive channel during expansion
Proc.Natl.Acad.Sci.USA, 112, 2015
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2O9Q
 | | The crystal structure of Bovine Trypsin complexed with a small inhibition peptide ORB2K | | Descriptor: | CALCIUM ION, Cationic trypsin, ORB2K, ... | | Authors: | Li, J, Zhang, C, Xu, X, Wang, J, Gong, W, Lai, R. | | Deposit date: | 2006-12-14 | | Release date: | 2007-12-25 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | From protease inhibitor to antibiotics: single point mutation makes tremendous functional shift
To be Published
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5YTK
 | | Crystal structure of SIRT3 bound to a leucylated AceCS2 | | Descriptor: | AceCS2-KLeu, LEUCINE, LYSINE, ... | | Authors: | Li, J, Gong, W, Xu, Y. | | Deposit date: | 2017-11-18 | | Release date: | 2017-12-27 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Sensing and Transmitting Intracellular Amino Acid Signals through Reversible Lysine Aminoacylations
Cell Metab., 27, 2018
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7F04
 | | Cytochrome c-type biogenesis protein CcmABCD from E. coli in complex with Heme and ATP. | | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, ADENOSINE-5'-TRIPHOSPHATE, Cytochrome c biogenesis ATP-binding export protein CcmA, ... | | Authors: | Li, J, Zheng, W, Gu, M, Zhang, K, Zhu, J.P. | | Deposit date: | 2021-06-03 | | Release date: | 2022-11-09 | | Method: | ELECTRON MICROSCOPY (2.86 Å) | | Cite: | Structures of the CcmABCD heme release complex at multiple states.
Nat Commun, 13, 2022
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6WQX
 | | Human PRPK-TPRKB complex | | Descriptor: | EKC/KEOPS complex subunit TP53RK, EKC/KEOPS complex subunit TPRKB, MAGNESIUM ION, ... | | Authors: | Li, J, Ma, X.L, Banerjee, S, Dong, Z.G. | | Deposit date: | 2020-04-29 | | Release date: | 2021-02-17 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.53 Å) | | Cite: | Crystal structure of the human PRPK-TPRKB complex.
Commun Biol, 4, 2021
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5HQC
 | | A Glycoside Hydrolase Family 97 enzyme R171K variant from Pseudoalteromonas sp. strain K8 | | Descriptor: | CALCIUM ION, CHLORIDE ION, FORMIC ACID, ... | | Authors: | Li, J, He, C, Xiao, Y. | | Deposit date: | 2016-01-21 | | Release date: | 2017-01-11 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.001 Å) | | Cite: | Structures of PspAG97A alpha-glucoside hydrolase reveal a novel mechanism for chloride induced activation.
J. Struct. Biol., 196, 2016
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6DQ3
 | | Streptococcus pyogenes deacetylase PplD in complex with acetate | | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, IMIDAZOLE, ... | | Authors: | Li, J, Korotkova, N, Korotkov, K.V. | | Deposit date: | 2018-06-10 | | Release date: | 2019-05-01 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (1.78 Å) | | Cite: | PplD is a de-N-acetylase of the cell wall linkage unit of streptococcal rhamnopolysaccharides
Nat Commun, 13, 2022
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5HQA
 | | A Glycoside Hydrolase Family 97 enzyme in complex with Acarbose from Pseudoalteromonas sp. strain K8 | | Descriptor: | 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, Alpha-glucosidase, CALCIUM ION, ... | | Authors: | Li, J, He, C, Xiao, Y. | | Deposit date: | 2016-01-21 | | Release date: | 2017-01-11 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.747 Å) | | Cite: | Structures of PspAG97A alpha-glucoside hydrolase reveal a novel mechanism for chloride induced activation.
J. Struct. Biol., 196, 2016
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5HQB
 | | A Glycoside Hydrolase Family 97 enzyme (E480Q) in complex with Panose from Pseudoalteromonas sp. strain K8 | | Descriptor: | Alpha-glucosidase, CALCIUM ION, CHLORIDE ION, ... | | Authors: | Li, J, He, C, Xiao, Y. | | Deposit date: | 2016-01-21 | | Release date: | 2017-01-11 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structures of PspAG97A alpha-glucoside hydrolase reveal a novel mechanism for chloride induced activation.
J. Struct. Biol., 196, 2016
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5HQ4
 | | A Glycoside Hydrolase Family 97 enzyme from Pseudoalteromonas sp. strain K8 | | Descriptor: | Alpha-glucosidase, CALCIUM ION, CHLORIDE ION, ... | | Authors: | Li, J, He, C, Xiao, Y. | | Deposit date: | 2016-01-21 | | Release date: | 2017-01-11 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.926 Å) | | Cite: | Structures of PspAG97A alpha-glucoside hydrolase reveal a novel mechanism for chloride induced activation.
J. Struct. Biol., 196, 2016
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