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PDB: 321 件

2DS2
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Crystal structure of mabinlin II
分子名称: ACETIC ACID, Sweet protein mabinlin-2 chain A, Sweet protein mabinlin-2 chain B
著者Li, D.F, Zhu, D.Y, Wang, D.C.
登録日2006-06-19
公開日2007-06-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of Mabinlin II: a novel structural type of sweet proteins and the main structural basis for its sweetness.
J.Struct.Biol., 162, 2008
3ZE5
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Crystal structure of the integral membrane diacylglycerol kinase - delta4
分子名称: DIACYLGLYCEROL KINASE
著者Li, D, Vogeley, L, Pye, V.E, Lyons, J.A, Aragao, D, Caffrey, M.
登録日2012-12-03
公開日2013-05-22
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.101 Å)
主引用文献Crystal Structure of the Integral Membrane Diacylglycerol Kinase.
Nature, 497, 2013
3ZE4
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Crystal structure of the integral membrane diacylglycerol kinase - wild-type
分子名称: DIACYLGLYCEROL KINASE
著者Li, D, Lyons, J.A, Pye, V.E, Vogeley, L, Aragao, D, Caffrey, M.
登録日2012-12-03
公開日2013-05-22
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.702 Å)
主引用文献Crystal Structure of the Integral Membrane Diacylglycerol Kinase.
Nature, 497, 2013
3BR8
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Crystal structure of acylphosphatase from Bacillus subtilis
分子名称: GLYCEROL, PHOSPHATE ION, Probable acylphosphatase
著者Li, D, Hu, J.C, Xia, B, Su, X.D.
登録日2007-12-21
公開日2008-06-24
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.33 Å)
主引用文献Conformational Transitions Revealed by Structures of Acylphosphatase from Bacillus subtilis in Different States
to be published
5XZR
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The atomic structure of SHP2 E76A mutant in complex with allosteric inhibitor 9b
分子名称: 4-(3-phenylphenyl)-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3-thiazol-2-amine, Tyrosine-protein phosphatase non-receptor type 11
著者Li, D, Xie, J, Zhu, J, Liu, C.
登録日2017-07-13
公開日2017-12-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Allosteric Inhibitors of SHP2 with Therapeutic Potential for Cancer Treatment.
J. Med. Chem., 60, 2017
5YZV
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Biophysical and structural characterization of the thermostable WD40 domain of a prokaryotic protein, Thermomonospora curvata PkwA
分子名称: Probable serine/threonine-protein kinase PkwA
著者Li, D.Y, Shen, C, Du, Y, Qiao, F.F, Kong, T, Yuan, L.R, Zhang, D.L, Wu, X.H, Wu, Y.D.
登録日2017-12-15
公開日2018-10-03
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Biophysical and structural characterization of the thermostable WD40 domain of a prokaryotic protein, Thermomonospora curvata PkwA
Sci Rep, 8, 2018
1NIY
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THREE DIMENSIONAL SOLUTION STRUCTURE OF HAINANTOXIN-IV BY 2D 1H-NMR
分子名称: HAINANTOXIN-IV
著者Li, D, Lu, S, Gu, X, Liang, S.
登録日2002-12-30
公開日2003-01-14
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Structure-Activity Relationships of Hainantoxin-IV and Structure Determination of Active and Inactive Sodium Channel Blockers.
J.Biol.Chem., 279, 2004
1NIX
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THREE DIMENSIONAL SOLUTION STRUCTURE OF HAINANTOXIN-I BY 2D 1H-NMR
分子名称: HAINANTOXIN-I
著者Li, D, Liang, S.
登録日2002-12-29
公開日2003-01-14
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Function and solution structure of hainantoxin-I, a novel insect sodium channel inhibitor from the Chinese bird spider Selenocosmia hainana.
Febs Lett., 555, 2003
1RYG
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Three dimensional solution structure of the R29A MUTANT of sodium channels inhibitor HAINANTOXIN-IV by 2D 1H-NMR
分子名称: Hainantoxin-IV
著者Li, D, Lu, S, Gu, X, Liang, S.
登録日2003-12-22
公開日2004-01-13
最終更新日2021-11-10
実験手法SOLUTION NMR
主引用文献Structure--activity relationships of hainantoxin-IV and structure determination of active and inactive sodium channel blockers
J.Biol.Chem., 279, 2004
1RYV
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Three dimensional solution structure of the K27A MUTANT of sodium channels inhibitor HAINANTOXIN-IV BY 2D 1H-NMR
分子名称: Hainantoxin-IV
著者Li, D, Lu, S, Gu, X, Liang, S.
登録日2003-12-22
公開日2004-01-13
最終更新日2021-11-10
実験手法SOLUTION NMR
主引用文献Structure--activity relationships of hainantoxin-IV and structure determination of active and inactive sodium channel blockers
J.Biol.Chem., 279, 2004
7E1Y
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Staphylothermus marinus amylopullulanase -SmApu
分子名称: Glycoside hydrolase, family 57
著者Li, D, Li, X, Woo, E.-J.
登録日2021-02-04
公開日2022-02-09
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Staphylothermus marinus amylopullulanase -SmApu
To Be Published
6LLB
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Crystal structure of mpy-RNase J (mutant S247A), an archaeal RNase J from Methanolobus psychrophilus R15, in complex with 6 nt RNA
分子名称: MPY-RNase J, RNA (5'-R(P*AP*AP*AP*AP*AP*A)-3'), SULFATE ION, ...
著者Li, D.F, Hou, Y.J, Guo, L.
登録日2019-12-22
公開日2020-01-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A newly identified duplex RNA unwinding activity of archaeal RNase J depends on processive exoribonucleolysis coupled steric occlusion by its structural archaeal loops.
Rna Biol., 17, 2020
5KIT
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Crystal Structure of Nicotinamide Phosphoribosyltransferase (Nampt) in Complex with Inhibitors 37
分子名称: 1,2-ETHANEDIOL, Nicotinamide phosphoribosyltransferase, PHOSPHATE ION, ...
著者Li, D, Wang, W.
登録日2016-06-17
公開日2016-08-31
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Minimizing CYP2C9 Inhibition of Exposed-Pyridine NAMPT (Nicotinamide Phosphoribosyltransferase) Inhibitors.
J.Med.Chem., 59, 2016
6IZ5
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Crystal Structure Analysis of a Eukaryotic Membrane Protein
分子名称: Trimeric intracellular cation channel type B-B
著者Li, D, Su, M, Hendrickson, W.A, Chen, Y.H.
登録日2018-12-18
公開日2019-05-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.701 Å)
主引用文献Structural basis for activity of TRIC counter-ion channels in calcium release.
Proc.Natl.Acad.Sci.USA, 116, 2019
6IYW
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Crystal sturucture of L,D-transpeptidase LdtMt2 from Mycobacterium tuberculosis in complex with Imipenem adduct
分子名称: (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carbox ylic acid, GLYCEROL, L,D-transpeptidase 2
著者Li, D.F, Zhao, F, Wang, D.C.
登録日2018-12-17
公開日2019-02-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The 1-beta-methyl group confers a lower affinity of l,d-transpeptidase LdtMt2 for ertapenem than for imipenem.
Biochem. Biophys. Res. Commun., 510, 2019
7C8Z
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Crystal structure of salicylate 5-hydroxylase NagGH (a Rieske non-heme iron-dependent monooxgenase)
分子名称: FE (III) ION, FE2/S2 (INORGANIC) CLUSTER, Salicylate 5-hydroxylase, ...
著者Li, D.F, Hou, Y.J.
登録日2020-06-04
公開日2021-01-06
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural and Biochemical Analysis Reveals a Distinct Catalytic Site of Salicylate 5-Monooxygenase NagGH from Rieske Dioxygenases.
Appl.Environ.Microbiol., 87, 2021
6LQB
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A third intermediate state of L,D-transpeptidase LdtMt2-ertapenem adduct
分子名称: (2S,3R,4S)-4-({(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl}sulfanyl)-2-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid, ACETIC ACID, GLYCEROL, ...
著者Li, D.F, Qin, Y.L.
登録日2020-01-13
公開日2021-01-13
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A New State I-plus Observed for the L,D-transpeptidase LdtMt2-ertapenem Adduct
Prog.Biochem.Biophys., 47, 2020
7W5N
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BU of 7w5n by Molmil
The crystal structure of the reduced form of Gluconobacter oxydans WSH-004 SNDH
分子名称: L-sorbosone dehydrogenase, NAD(P) dependent, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Li, D, Hou, X.D, Rao, Y.J, Yin, D.J, Zhou, J.W, Chen, J.
登録日2021-11-30
公開日2023-03-01
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.988 Å)
主引用文献Structural Insight into the Catalytic Mechanisms of an L-Sorbosone Dehydrogenase.
Adv Sci, 10, 2023
7W5K
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The C296A mutant of L-sorbosone dehydrogenase (SNDH) from Gluconobacter Oxydans WSH-004
分子名称: L-sorbosone dehydrogenase, NAD(P) dependent, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Li, D, Hou, X.D, Rao, Y.J, Zhou, J.W, Chen, J.
登録日2021-11-30
公開日2023-03-01
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Structural Insight into the Catalytic Mechanisms of an L-Sorbosone Dehydrogenase.
Adv Sci, 10, 2023
7YL0
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Structure of hIAPP-TF-type2
分子名称: Islet amyloid polypeptide
著者Li, D, Zhang, X, Wang, Y, Zhu, P.
登録日2022-07-25
公開日2022-12-28
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献A new polymorphism of human amylin fibrils with similar protofilaments and a conserved core.
Iscience, 25, 2022
7YL3
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Structure of hIAPP-TF-type1
分子名称: Islet amyloid polypeptide
著者Li, D, Zhang, X, Wang, Y, Zhu, P.
登録日2022-07-25
公開日2022-12-28
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献A new polymorphism of human amylin fibrils with similar protofilaments and a conserved core.
Iscience, 25, 2022
7YL7
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Structure of hIAPP-TF-type3
分子名称: Islet amyloid polypeptide
著者Li, D, Zhang, X.
登録日2022-07-25
公開日2022-12-28
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献A new polymorphism of human amylin fibrils with similar protofilaments and a conserved core.
Iscience, 25, 2022
5IME
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Crystal structure of P21-activated kinase 1 (PAK1) in complex with compound 9
分子名称: 8-(3-aminopropyl)-6-[2-chloro-4-(3-methyl-2-oxopyrazin-1(2H)-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8H)-one, Serine/threonine-protein kinase PAK 1
著者Li, D, Wang, W.
登録日2016-03-06
公開日2016-05-25
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.217 Å)
主引用文献Chemically Diverse Group I p21-Activated Kinase (PAK) Inhibitors Impart Acute Cardiovascular Toxicity with a Narrow Therapeutic Window.
J.Med.Chem., 59, 2016
7W5L
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The crystal structure of the oxidized form of Gluconobacter oxydans WSH-004 SNDH
分子名称: L-sorbosone dehydrogenase, NAD(P) dependent
著者Li, D, Hou, X.D, Rao, Y.J, Zhou, J.W, Chen, J.
登録日2021-11-30
公開日2023-01-18
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Insight into the Catalytic Mechanisms of an L-Sorbosone Dehydrogenase.
Adv Sci, 10, 2023
7YKW
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Structure of hIAPP fibril at 3.6 Angstroms resolution
分子名称: Islet amyloid polypeptide
著者Li, D, Zhang, X, Wang, Y, Zhu, P.
登録日2022-07-25
公開日2023-01-18
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献A new polymorphism of human amylin fibrils with similar protofilaments and a conserved core.
Iscience, 25, 2022

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