Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 326 件
6H6V
DownloadVisualize
BU of 6h6v by Molmil
Structure of the UbiD-class enzyme HmfF from Pelotomaculum thermopropionicum in complex with FMN
分子名称: 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases, CALCIUM ION, FLAVIN MONONUCLEOTIDE, ...
著者Payne, K.A.P, Leys, D.
登録日2018-07-30
公開日2019-02-27
最終更新日2019-05-15
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献Enzymatic Carboxylation of 2-Furoic Acid Yields 2,5-Furandicarboxylic Acid (FDCA).
Acs Catalysis, 9, 2019
6FOZ
DownloadVisualize
BU of 6foz by Molmil
The crystal structure of P.fluorescens Kynurenine 3-monooxygenase (KMO) in complex with competitive inhibitor No. 13
分子名称: 5-(3,4-dichlorophenyl)furan-2-carboxylic acid, FLAVIN-ADENINE DINUCLEOTIDE, Kynurenine 3-monooxygenase
著者Levy, C.W, Leys, D.
登録日2018-02-08
公開日2019-08-21
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献A brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase prevents accumulation of neurotoxic metabolites.
Commun Biol, 2, 2019
6H1T
DownloadVisualize
BU of 6h1t by Molmil
Structure of the BM3 heme domain in complex with clotrimazole
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1-[(2-CHLOROPHENYL)(DIPHENYL)METHYL]-1H-IMIDAZOLE, ...
著者Jeffreys, L.N, Munro, A.W.M, Leys, D.
登録日2018-07-12
公開日2019-02-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Novel insights into P450 BM3 interactions with FDA-approved antifungal azole drugs.
Sci Rep, 9, 2019
6FYJ
DownloadVisualize
BU of 6fyj by Molmil
Cytochrome P450 peroxygenase CYP152K6 in complex with Myristic Acid
分子名称: DI(HYDROXYETHYL)ETHER, Fatty-acid peroxygenase, MYRISTIC ACID, ...
著者Girvan, H.M, Poddar, H, Mclean, K.J, Leys, D, Munro, A.W.
登録日2018-03-12
公開日2018-08-22
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structural and catalytic properties of the peroxygenase P450 enzyme CYP152K6 from Bacillus methanolicus.
J. Inorg. Biochem., 188, 2018
5N6Q
DownloadVisualize
BU of 5n6q by Molmil
Xenobiotic reductase A (XenA) from Pseudomonas putida in complex with 2-phenylacrylic acid
分子名称: 2-Phenylacrylic acid, CHLORIDE ION, FLAVIN MONONUCLEOTIDE, ...
著者Karuppiah, V, Toogood, H.S, Leys, D, Scrutton, N.S.
登録日2017-02-15
公開日2017-05-17
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural insights into the ene-reductase synthesis of profens.
Org. Biomol. Chem., 15, 2017
5M1B
DownloadVisualize
BU of 5m1b by Molmil
Crystal structure of C-terminally tagged apo-UbiD from E. coli
分子名称: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
著者White, M, Leys, D.
登録日2016-10-07
公開日2017-01-11
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Oxidative Maturation and Structural Characterization of Prenylated FMN Binding by UbiD, a Decarboxylase Involved in Bacterial Ubiquinone Biosynthesis.
J. Biol. Chem., 292, 2017
5NX6
DownloadVisualize
BU of 5nx6 by Molmil
Crystal structure of 1,8-cineole synthase from Streptomyces clavuligerus in complex with 2-fluoroneryl diphosphate
分子名称: (2E)-2-fluoro-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate, 2-ethyl-2-(hydroxymethyl)propane-1,3-diol, ETHYL DIMETHYL AMMONIO PROPANE SULFONATE, ...
著者Karuppiah, V, Leys, D, Scrutton, N.S.
登録日2017-05-09
公開日2017-09-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Structural Basis of Catalysis in the Bacterial Monoterpene Synthases Linalool Synthase and 1,8-Cineole Synthase.
ACS Catal, 7, 2017
5O3N
DownloadVisualize
BU of 5o3n by Molmil
Crystal structure of E. cloacae 3,4-dihydroxybenzoic acid decarboxylase (AroY) reconstituted with prFMN
分子名称: 1-deoxy-5-O-phosphono-1-(3,3,4,5-tetramethyl-9,11-dioxo-2,3,8,9,10,11-hexahydro-7H-quinolino[1,8-fg]pteridin-12-ium-7-y l)-D-ribitol, 3,4-dihydroxybenzoate decarboxylase, GLYCEROL, ...
著者Marshall, S.A, Leys, D.
登録日2017-05-24
公開日2017-09-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Regioselective para-Carboxylation of Catechols with a Prenylated Flavin Dependent Decarboxylase.
Angew. Chem. Int. Ed. Engl., 56, 2017
5N6G
DownloadVisualize
BU of 5n6g by Molmil
NerA from Agrobacterium radiobacter in complex with 2-phenylacrylic acid
分子名称: 2-Phenylacrylic acid, ACETATE ION, FLAVIN MONONUCLEOTIDE, ...
著者Karuppiah, V, Toogood, H.S, Leys, D, Scrutton, N.S.
登録日2017-02-15
公開日2017-05-17
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Structural insights into the ene-reductase synthesis of profens.
Org. Biomol. Chem., 15, 2017
5M1C
DownloadVisualize
BU of 5m1c by Molmil
Crystal structure of N-terminally tagged apo-UbiD from E. coli
分子名称: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase, TETRAETHYLENE GLYCOL
著者Marshall, S.A, Leys, D.
登録日2016-10-07
公開日2017-01-11
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Oxidative Maturation and Structural Characterization of Prenylated FMN Binding by UbiD, a Decarboxylase Involved in Bacterial Ubiquinone Biosynthesis.
J. Biol. Chem., 292, 2017
5NY5
DownloadVisualize
BU of 5ny5 by Molmil
The apo structure of 3,4-dihydroxybenzoic acid decarboxylases from Enterobacter cloacae
分子名称: 3,4-dihydroxybenzoate decarboxylase, GLYCEROL
著者Dordic, A, Gruber, K, Payer, S, Glueck, S, Pavkov-Keller, T, Marshall, S, Leys, D.
登録日2017-05-11
公開日2017-09-13
最終更新日2020-11-18
実験手法X-RAY DIFFRACTION (2.501 Å)
主引用文献Regioselective para-Carboxylation of Catechols with a Prenylated Flavin Dependent Decarboxylase.
Angew. Chem. Int. Ed. Engl., 56, 2017
5NX5
DownloadVisualize
BU of 5nx5 by Molmil
Crystal structure of Linalool/Nerolidol synthase from Streptomyces clavuligerus in complex with 2-fluorogeranyl diphosphate
分子名称: (2Z)-2-fluoro-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate, CHLORIDE ION, GLYCEROL, ...
著者Karuppiah, V, Leys, D, Scrutton, N.S.
登録日2017-05-09
公開日2017-09-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Structural Basis of Catalysis in the Bacterial Monoterpene Synthases Linalool Synthase and 1,8-Cineole Synthase.
ACS Catal, 7, 2017
5O3M
DownloadVisualize
BU of 5o3m by Molmil
Crystal structure of apo Klebsiella pneumoniae 3,4-dihydroxybenzoic acid decarboxylase (AroY)
分子名称: Protocatechuate decarboxylase, pentane-1,5-diol
著者Marshall, S.A, Leys, D.
登録日2017-05-24
公開日2017-09-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Regioselective para-Carboxylation of Catechols with a Prenylated Flavin Dependent Decarboxylase.
Angew. Chem. Int. Ed. Engl., 56, 2017
5NX7
DownloadVisualize
BU of 5nx7 by Molmil
Crystal structure of 1,8-cineole synthase from Streptomyces clavuligerus in complex with 2-fluoroneryl diphosphate and 2-fluorogeranyl diphosphate
分子名称: (2E)-2-fluoro-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate, (2Z)-2-fluoro-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate, 2-ethyl-2-(hydroxymethyl)propane-1,3-diol, ...
著者Karuppiah, V, Leys, D, Scrutton, N.S.
登録日2017-05-09
公開日2017-09-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Structural Basis of Catalysis in the Bacterial Monoterpene Synthases Linalool Synthase and 1,8-Cineole Synthase.
ACS Catal, 7, 2017
5NX4
DownloadVisualize
BU of 5nx4 by Molmil
Crystal structure of Linalool/Nerolidol synthase from Streptomyces clavuligerus
分子名称: GLYCEROL, Pentalenene synthase
著者Karuppiah, V, Leys, D, Scrutton, N.S.
登録日2017-05-09
公開日2017-09-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Structural Basis of Catalysis in the Bacterial Monoterpene Synthases Linalool Synthase and 1,8-Cineole Synthase.
ACS Catal, 7, 2017
5OG9
DownloadVisualize
BU of 5og9 by Molmil
The BM3 mutant WIFI-WC heme domain in complex with testosterone
分子名称: Bifunctional cytochrome P450/NADPH--P450 reductase, CHLORIDE ION, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Gamble, C, Munro, A.W, Leys, D.
登録日2017-07-12
公開日2018-08-01
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Regio- and diastereoselective hydroxylation of steroids using P450-BM3: Readdressing the numbers problem in directed evolution
To Be Published
2IUV
DownloadVisualize
BU of 2iuv by Molmil
CRYSTAL STRUCTURE OF N-QUINOL FORM OF AROMATIC AMINE DEHYDROGENASE (AADH) FROM ALCALIGENES FAECALIS, FORM B
分子名称: AROMATIC AMINE DEHYDROGENASE ALPHA SUBUNIT, AROMATIC AMINE DEHYDROGENASE BETA SUBUNIT
著者Roujeinikova, A, Scrutton, N, Leys, D.
登録日2006-06-07
公開日2006-09-20
最終更新日2019-02-06
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Atomic level insight into the oxidative half-reaction of aromatic amine dehydrogenase.
J. Biol. Chem., 281, 2006
2IJ3
DownloadVisualize
BU of 2ij3 by Molmil
Structure of the A264H mutant of cytochrome P450 BM3
分子名称: Cytochrome P450 BM3, PROTOPORPHYRIN IX CONTAINING FE
著者Toogood, H.S, Leys, D.
登録日2006-09-29
公開日2006-11-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and spectroscopic characterization of P450 BM3 mutants with unprecedented P450 heme iron ligand sets. New heme ligation states influence conformational equilibria in P450 BM3.
J.Biol.Chem., 282, 2007
2HKR
DownloadVisualize
BU of 2hkr by Molmil
Structures of the carbinolamine and schiff-base intermediates in the reductive half-reaction of aromatic amine dehydrogenase (AADH) with p-methoxyphenylethylamine
分子名称: 2-(4-METHOXYPHENYL)ACETAMIDE, 2-(4-METHOXYPHENYL)ETHANAMINE, Aromatic amine dehydrogenase, ...
著者Roujeinikova, A, Leys, D.
登録日2006-07-05
公開日2008-04-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structure-reactivity correlations and kinetic isotope effects in aromatic amine dehydrogenase
To be Published
2IAA
DownloadVisualize
BU of 2iaa by Molmil
Crystal Structure of an Electron Transfer Complex Between Aromatic Amine Dephydrogenase and Azurin from Alcaligenes Faecalis (Form 2)
分子名称: Aromatic Amine Dehydrogenase, Azurin, COPPER (II) ION
著者Sukumar, N, Chen, Z, Leys, D, Scrutton, N.S, Ferrati, D, Merli, A, Rossi, G.L, Bellamy, H.D, Chistoserdov, A, Davidson, V.L, Mathews, F.S.
登録日2006-09-07
公開日2006-11-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal Structure of an Electron Transfer Complex between Aromatic Amine Dehydrogenase and Azurin from Alcaligenes faecalis.
Biochemistry, 45, 2006
2IUR
DownloadVisualize
BU of 2iur by Molmil
CRYSTAL STRUCTURE OF N-QUINOL FORM OF AROMATIC AMINE DEHYDROGENASE (AADH) FROM ALCALIGENES FAECALIS, FORM A COCRYSTAL
分子名称: AROMATIC AMINE DEHYDROGENASE ALPHA SUBUNIT, AROMATIC AMINE DEHYDROGENASE BETA SUBUNIT
著者Roujeinikova, A, Scrutton, N, Leys, D.
登録日2006-06-07
公開日2006-09-20
最終更新日2019-02-06
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Atomic Level Insight Into the Oxidative Half-Reaction of Aromatic Amine Dehydrogenase.
J.Biol.Chem., 281, 2006
2IJ4
DownloadVisualize
BU of 2ij4 by Molmil
Structure of the A264K mutant of cytochrome P450 BM3
分子名称: PROTOPORPHYRIN IX CONTAINING FE, cytochrome P450 BM3
著者Toogood, H.S, Leys, D.
登録日2006-09-29
公開日2006-11-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural and spectroscopic characterization of P450 BM3 mutants with unprecedented P450 heme iron ligand sets. New heme ligation states influence conformational equilibria in P450 BM3.
J.Biol.Chem., 282, 2007
2I0T
DownloadVisualize
BU of 2i0t by Molmil
Crystal structure of phenylacetaldehyde derived R-carbinolamine adduct of aromatic amine dehydrogenase
分子名称: 2-PHENYL-ETHANOL, Aromatic amine dehydrogenase
著者Roujeinikova, A, Leys, D.
登録日2006-08-11
公開日2007-04-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献New insights into the reductive half-reaction mechanism of aromatic amine dehydrogenase revealed by reaction with carbinolamine substrates.
J.Biol.Chem., 282, 2007
2IJ5
DownloadVisualize
BU of 2ij5 by Molmil
Crystal structure of cytochrome P450 CYP121, P212121 space group
分子名称: Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
著者Roujeinikova, A, Leys, D.
登録日2006-09-29
公開日2006-11-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of the Mycobacterium tuberculosis P450 CYP121-fluconazole complex reveals new azole drug-P450 binding mode.
J.Biol.Chem., 281, 2006
2IUP
DownloadVisualize
BU of 2iup by Molmil
CRYSTAL STRUCTURE OF DITHIONITE-REDUCED AROMATIC AMINE DEHYDROGENASE (AADH) FROM ALCALIGENES FAECALIS
分子名称: AROMATIC AMINE DEHYDROGENASE ALPHA SUBUNIT, AROMATIC AMINE DEHYDROGENASE BETA SUBUNIT
著者Roujeinikova, A, Scrutton, N, Leys, D.
登録日2006-06-07
公開日2006-09-20
最終更新日2019-02-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Atomic level insight into the oxidative half-reaction of aromatic amine dehydrogenase.
J. Biol. Chem., 281, 2006

221051

件を2024-06-12に公開中

PDB statisticsPDBj update infoContact PDBjnumon