5M0P
| Crystal structure of cytochrome P450 OleT F79A in complex with arachidonic acid | 分子名称: | PROTOPORPHYRIN IX CONTAINING FE, SODIUM ION, Terminal olefin-forming fatty acid decarboxylase, ... | 著者 | Tee, K.L, Munro, A, Matthews, S, Leys, D, Levy, C. | 登録日 | 2016-10-05 | 公開日 | 2017-01-11 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Catalytic Determinants of Alkene Production by the Cytochrome P450 Peroxygenase OleTJE. J. Biol. Chem., 292, 2017
|
|
5M0N
| Crystal structure of cytochrome P450 OleT in complex with formate | 分子名称: | FORMIC ACID, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ... | 著者 | Tee, K.L, Munro, A, Matthews, S, Leys, D, Levy, C. | 登録日 | 2016-10-05 | 公開日 | 2017-01-11 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | 主引用文献 | Catalytic Determinants of Alkene Production by the Cytochrome P450 Peroxygenase OleTJE. J. Biol. Chem., 292, 2017
|
|
2QTL
| Crystal Structure of the FAD-containing FNR-like Module of Human Methionine Synthase Reductase | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Methionine synthase reductase | 著者 | Wolthers, K.R, Lou, X, Toogood, H.S, Leys, D, Scrutton, N.S. | 登録日 | 2007-08-02 | 公開日 | 2007-11-13 | 最終更新日 | 2022-12-21 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Mechanism of Coenzyme Binding to Human Methionine Synthase Reductase Revealed through the Crystal Structure of the FNR-like Module and Isothermal Titration Calorimetry Biochemistry, 46, 2007
|
|
6H6X
| Structure of an evolved dimeric form of the UbiD-class enzyme HmfF from Pelotomaculum thermopropionicum in complex with prFMN | 分子名称: | 1-deoxy-5-O-phosphono-1-(3,3,4,5-tetramethyl-9,11-dioxo-2,3,8,9,10,11-hexahydro-7H-quinolino[1,8-fg]pteridin-12-ium-7-y l)-D-ribitol, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases, CALCIUM ION, ... | 著者 | Payne, K.A.P, Leys, D. | 登録日 | 2018-07-30 | 公開日 | 2019-02-27 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Enzymatic Carboxylation of 2-Furoic Acid Yields 2,5-Furandicarboxylic Acid (FDCA). Acs Catalysis, 9, 2019
|
|
5M1C
| |
5M1B
| |
2A1T
| Structure of the human MCAD:ETF E165betaA complex | 分子名称: | ADENOSINE MONOPHOSPHATE, Acyl-CoA dehydrogenase, medium-chain specific, ... | 著者 | Toogood, H.S, Van Thiel, A, Scrutton, N.S, Leys, D. | 登録日 | 2005-06-21 | 公開日 | 2005-07-05 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Stabilization of Non-productive Conformations Underpins Rapid Electron Transfer to Electron-transferring Flavoprotein J.Biol.Chem., 280, 2005
|
|
2AGW
| Crystal structure of tryptamine-reduced aromatic amine dehydrogenase (AADH) from Alcaligenes faecalis in complex with tryptamine | 分子名称: | 2-(1H-INDOL-3-YL)ETHANAMINE, Aromatic amine dehydrogenase | 著者 | Masgrau, L, Roujeinikova, A, Johannissen, L.O, Hothi, P, Basran, J, Ranaghan, K.E, Mulholland, A.J, Sutcliffe, M.J, Scrutton, N.S, Leys, D. | 登録日 | 2005-07-27 | 公開日 | 2006-04-25 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Atomic description of an enzyme reaction dominated by proton tunneling Science, 312, 2006
|
|
2AGL
| Crystal structure of the phenylhydrazine adduct of aromatic amine dehydrogenase from Alcaligenes faecalis | 分子名称: | 1-PHENYLHYDRAZINE, Aromatic amine dehydrogenase | 著者 | Masgrau, L, Roujeinikova, A, Johannissen, L.O, Hothi, P, Basran, J, Ranaghan, K.E, Mulholland, A.J, Sutcliffe, M.J, Scrutton, N.S, Leys, D. | 登録日 | 2005-07-27 | 公開日 | 2006-04-25 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Atomic description of an enzyme reaction dominated by proton tunneling Science, 312, 2006
|
|
2AGY
| Crystal structure of the Schiff base intermediate in the reductive half-reaction of aromatic amine dehydrogenase (AADH) with tryptamine. Monoclinic form | 分子名称: | 2-(1H-INDOL-3-YL)ETHANIMINE, Aromatic amine dehydrogenase | 著者 | Masgrau, L, Roujeinikova, A, Johannissen, L.O, Hothi, P, Basran, J, Ranaghan, K.E, Mulholland, A.J, Sutcliffe, M.J, Scrutton, N.S, Leys, D. | 登録日 | 2005-07-27 | 公開日 | 2006-04-25 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Atomic description of an enzyme reaction dominated by proton tunneling Science, 312, 2006
|
|
1JNI
| Structure of the NapB subunit of the periplasmic nitrate reductase from Haemophilus influenzae. | 分子名称: | DIHEME CYTOCHROME C NAPB, HEME C | 著者 | Brige, A, Leys, D, Meyer, T.E, Cusanovich, M.A, Van Beeumen, J.J. | 登録日 | 2001-07-24 | 公開日 | 2002-05-17 | 最終更新日 | 2021-03-03 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | The 1.25 A resolution structure of the diheme NapB subunit of soluble nitrate reductase reveals a novel cytochrome c fold with a stacked heme arrangement. Biochemistry, 41, 2002
|
|
2A1U
| Crystal structure of the human ETF E165betaA mutant | 分子名称: | ADENOSINE MONOPHOSPHATE, Electron transfer flavoprotein alpha-subunit, mitochondrial precursor, ... | 著者 | Toogood, H.S, Van Thiel, A, Scrutton, N.S, Leys, D. | 登録日 | 2005-06-21 | 公開日 | 2005-07-05 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | Stabilization of Non-productive Conformations Underpins Rapid Electron Transfer to Electron-transferring Flavoprotein J.Biol.Chem., 280, 2005
|
|
2ABA
| Structure of reduced PETN reductase in complex with progesterone | 分子名称: | FLAVIN MONONUCLEOTIDE, ISOPROPYL ALCOHOL, PROGESTERONE, ... | 著者 | Khan, H, Barna, T, Bruce, N.C, Munro, A.W, Leys, D, Scrutton, N.S. | 登録日 | 2005-07-15 | 公開日 | 2005-10-11 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | 主引用文献 | Proton transfer in the oxidative half-reaction of pentaerythritol tetranitrate reductase Febs J., 272, 2005
|
|
2ABB
| Structure of PETN reductase Y186F in complex with cyanide | 分子名称: | FLAVIN MONONUCLEOTIDE, ISOPROPYL ALCOHOL, THIOCYANATE ION, ... | 著者 | Khan, H, Barna, T, Bruce, N.C, Munro, A.W, Leys, D, Scrutton, N.S. | 登録日 | 2005-07-15 | 公開日 | 2005-10-11 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1 Å) | 主引用文献 | Proton transfer in the oxidative half-reaction of pentaerythritol tetranitrate reductase Febs J., 272, 2005
|
|
2AH1
| Crystal structure of aromatic amine dehydrogenase (AADH) from Alcaligenes faecalis | 分子名称: | Aromatic amine dehydrogenase | 著者 | Masgrau, L, Roujeinikova, A, Johannissen, L.O, Hothi, P, Basran, J, Ranaghan, K.E, Mulholland, A.J, Sutcliffe, M.J, Scrutton, N.S, Leys, D. | 登録日 | 2005-07-27 | 公開日 | 2006-04-25 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Atomic description of an enzyme reaction dominated by proton tunneling Science, 312, 2006
|
|
6EVB
| Structure of E282Q A. niger Fdc1 with prFMN in the iminium form | 分子名称: | 1-deoxy-5-O-phosphono-1-(3,3,4,5-tetramethyl-9,11-dioxo-2,3,8,9,10,11-hexahydro-7H-quinolino[1,8-fg]pteridin-12-ium-7-y l)-D-ribitol, Ferulic acid decarboxylase 1, MANGANESE (II) ION, ... | 著者 | Bailey, S.S, Leys, D, Payne, K.A.P. | 登録日 | 2017-11-01 | 公開日 | 2017-12-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.13 Å) | 主引用文献 | The role of conserved residues in Fdc decarboxylase in prenylated flavin mononucleotide oxidative maturation, cofactor isomerization, and catalysis. J. Biol. Chem., 293, 2018
|
|
2AGX
| Crystal structure of the Schiff base intermediate in the reductive half-reaction of aromatic amine dehydrogenase (AADH) with tryptamine. P212121 form | 分子名称: | 2-(1H-INDOL-3-YL)ETHANIMINE, Aromatic amine dehydrogenase | 著者 | Masgrau, L, Roujeinikova, A, Johannissen, L.O, Hothi, P, Basran, J, Ranaghan, K.E, Mulholland, A.J, Sutcliffe, M.J, Scrutton, N.S, Leys, D. | 登録日 | 2005-07-27 | 公開日 | 2006-04-25 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Atomic description of an enzyme reaction dominated by proton tunneling Science, 312, 2006
|
|
6EV7
| Structure of E282D A. niger Fdc1 with prFMN in the iminium form | 分子名称: | 1-deoxy-5-O-phosphono-1-(3,3,4,5-tetramethyl-9,11-dioxo-2,3,8,9,10,11-hexahydro-7H-quinolino[1,8-fg]pteridin-12-ium-7-y l)-D-ribitol, Ferulic acid decarboxylase 1, MANGANESE (II) ION, ... | 著者 | Bailey, S.S, Leys, D, Payne, K.A.P. | 登録日 | 2017-11-01 | 公開日 | 2017-12-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.06 Å) | 主引用文献 | The role of conserved residues in Fdc decarboxylase in prenylated flavin mononucleotide oxidative maturation, cofactor isomerization, and catalysis. J. Biol. Chem., 293, 2018
|
|
2AH0
| Crystal structure of the carbinolamine intermediate in the reductive half-reaction of aromatic amine dehydrogenase (AADH) with tryptamine. Monoclinic form | 分子名称: | (1S)-1-AMINO-2-(1H-INDOL-3-YL)ETHANOL, 2-(1H-INDOL-3-YL)ETHANIMINE, Aromatic amine dehydrogenase | 著者 | Masgrau, L, Roujeinikova, A, Johannissen, L.O, Hothi, P, Basran, J, Ranaghan, K.E, Mulholland, A.J, Sutcliffe, M.J, Scrutton, N.S, Leys, D. | 登録日 | 2005-07-27 | 公開日 | 2006-04-25 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Atomic description of an enzyme reaction dominated by proton tunneling Science, 312, 2006
|
|
6FYJ
| Cytochrome P450 peroxygenase CYP152K6 in complex with Myristic Acid | 分子名称: | DI(HYDROXYETHYL)ETHER, Fatty-acid peroxygenase, MYRISTIC ACID, ... | 著者 | Girvan, H.M, Poddar, H, Mclean, K.J, Leys, D, Munro, A.W. | 登録日 | 2018-03-12 | 公開日 | 2018-08-22 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Structural and catalytic properties of the peroxygenase P450 enzyme CYP152K6 from Bacillus methanolicus. J. Inorg. Biochem., 188, 2018
|
|
5L4S
| Isopiperitenone reductase from Mentha piperita in complex with NADP and beta-Cyclocitral | 分子名称: | (-)-isopiperitenone reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, beta-cyclocitral | 著者 | Karuppiah, V, Toogood, H.S, Leys, D, Scrutton, N.S. | 登録日 | 2016-05-26 | 公開日 | 2016-08-31 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | 主引用文献 | Pinpointing a Mechanistic Switch Between Ketoreduction and "Ene" Reduction in Short-Chain Dehydrogenases/Reductases. Angew.Chem.Int.Ed.Engl., 55, 2016
|
|
5LIE
| |
5LDG
| Isopiperitenone reductase from Mentha piperita in complex with Isopiperitenone and NADP | 分子名称: | (-)-Isopiperitenone, (-)-isopiperitenone reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Karuppiah, V, Toogood, H.S, Leys, D, Scrutton, N.S. | 登録日 | 2016-06-26 | 公開日 | 2016-08-31 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Pinpointing a Mechanistic Switch Between Ketoreduction and "Ene" Reduction in Short-Chain Dehydrogenases/Reductases. Angew.Chem.Int.Ed.Engl., 55, 2016
|
|
5LCX
| Isopiperitenone reductase from Mentha piperita in complex with NADP | 分子名称: | (-)-isopiperitenone reductase, (4S)-2-METHYL-2,4-PENTANEDIOL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Karuppiah, V, Toogood, H.S, Leys, D, Scrutton, N.S. | 登録日 | 2016-06-22 | 公開日 | 2016-08-31 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.709 Å) | 主引用文献 | Pinpointing a Mechanistic Switch Between Ketoreduction and "Ene" Reduction in Short-Chain Dehydrogenases/Reductases. Angew.Chem.Int.Ed.Engl., 55, 2016
|
|
5LTM
| |